{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T00:32:30Z","timestamp":1790037150605,"version":"4.0.1"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2023,1,13]],"date-time":"2023-01-13T00:00:00Z","timestamp":1673568000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,1,13]],"date-time":"2023-01-13T00:00:00Z","timestamp":1673568000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J Clin Oncol"],"published-print":{"date-parts":[[2023,3]]},"DOI":"10.1007\/s10147-023-02293-2","type":"journal-article","created":{"date-parts":[[2023,1,13]],"date-time":"2023-01-13T11:07:23Z","timestamp":1673608043000},"page":"400-408","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["The impact of the advanced lung cancer inflammation index on the outcomes of patients with metastatic colorectal cancer who receive chemotherapy"],"prefix":"10.1007","volume":"28","author":[{"given":"Taichi","family":"Horino","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryuma","family":"Tokunaga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuji","family":"Miyamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukiharu","family":"Hiyoshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiko","family":"Akiyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuya","family":"Daitoku","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuki","family":"Sakamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoya","family":"Yoshida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideo","family":"Baba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,1,13]]},"reference":[{"issue":"2","key":"2293_CR1","first-page":"89","volume":"14","author":"P Rawla","year":"2019","unstructured":"Rawla P, Sunkara T, Barsouk A (2019) Epidemiology of colorectal cancer: incidence, mortality, survival, and risk factors. Prz Gastroenterol 14(2):89\u2013103","journal-title":"Prz Gastroenterol"},{"issue":"13","key":"2293_CR2","doi-asserted-by":"publisher","first-page":"1177","DOI":"10.1056\/NEJMoa1713709","volume":"378","author":"A Grothey","year":"2018","unstructured":"Grothey A et al (2018) Duration of adjuvant chemotherapy for stage III colon cancer. N Engl J Med 378(13):1177\u20131188","journal-title":"N Engl J Med"},{"issue":"7","key":"2293_CR3","doi-asserted-by":"publisher","first-page":"1110","DOI":"10.1002\/bjs.7032","volume":"97","author":"EJ Morris","year":"2010","unstructured":"Morris EJ et al (2010) Surgical management and outcomes of colorectal cancer liver metastases. Br J Surg 97(7):1110\u20131118","journal-title":"Br J Surg"},{"issue":"11","key":"2293_CR4","doi-asserted-by":"publisher","first-page":"1490","DOI":"10.1001\/jamaoncol.2016.2214","volume":"2","author":"KK Dijkstra","year":"2016","unstructured":"Dijkstra KK et al (2016) Genomics- and transcriptomics-based patient selection for cancer treatment with immune checkpoint inhibitors: a review. JAMA Oncol 2(11):1490\u20131495","journal-title":"JAMA Oncol"},{"issue":"9","key":"2293_CR5","doi-asserted-by":"publisher","first-page":"1182","DOI":"10.1016\/S1470-2045(17)30422-9","volume":"18","author":"MJ Overman","year":"2017","unstructured":"Overman MJ et al (2017) Nivolumab in patients with metastatic DNA mismatch repair-deficient or microsatellite instability-high colorectal cancer (CheckMate 142): an open-label, multicentre, phase 2 study. Lancet Oncol 18(9):1182\u20131191","journal-title":"Lancet Oncol"},{"issue":"2","key":"2293_CR6","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1002\/jso.25961","volume":"122","author":"Y Miyamoto","year":"2020","unstructured":"Miyamoto Y et al (2020) Postoperative complications are associated with poor survival outcome after curative resection for colorectal cancer: a propensity-score analysis. J Surg Oncol 122(2):344\u2013349","journal-title":"J Surg Oncol"},{"issue":"5","key":"2293_CR7","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1097\/00000658-200211000-00015","volume":"236","author":"DW Wilmore","year":"2002","unstructured":"Wilmore DW (2002) From cuthbertson to fast-track surgery: 70 years of progress in reducing stress in surgical patients. Ann Surg 236(5):643\u2013648","journal-title":"Ann Surg"},{"issue":"Suppl 2","key":"2293_CR8","doi-asserted-by":"publisher","first-page":"S257","DOI":"10.1245\/s10434-015-4466-7","volume":"23","author":"Y Matsumoto","year":"2016","unstructured":"Matsumoto Y et al (2016) Abdominal infection suppresses the number and activity of intrahepatic natural killer cells and promotes tumor growth in a murine liver metastasis model. Ann Surg Oncol 23(Suppl 2):S257\u2013S265","journal-title":"Ann Surg Oncol"},{"key":"2293_CR9","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1186\/1471-2407-13-158","volume":"13","author":"SH Jafri","year":"2013","unstructured":"Jafri SH, Shi R, Mills G (2013) Advance lung cancer inflammation index (ALI) at diagnosis is a prognostic marker in patients with metastatic non-small cell lung cancer (NSCLC): a retrospective review. BMC Cancer 13:158","journal-title":"BMC Cancer"},{"issue":"2","key":"2293_CR10","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1159\/000452991","volume":"137","author":"YH Park","year":"2017","unstructured":"Park YH et al (2017) Prognostic value of the pretreatment advanced lung cancer inflammation index (ALI) in diffuse large B cell lymphoma patients treated with R-CHOP chemotherapy. Acta Haematol 137(2):76\u201385","journal-title":"Acta Haematol"},{"key":"2293_CR11","doi-asserted-by":"publisher","first-page":"8807","DOI":"10.2147\/CMAR.S222297","volume":"11","author":"E Topkan","year":"2019","unstructured":"Topkan E et al (2019) Prognostic usefulness of advanced lung cancer inflammation index in locally-advanced pancreatic carcinoma patients treated with radical chemoradiotherapy. Cancer Manag Res 11:8807\u20138815","journal-title":"Cancer Manag Res"},{"key":"2293_CR12","doi-asserted-by":"publisher","first-page":"2513026","DOI":"10.1155\/2019\/2513026","volume":"2019","author":"Y Zhang","year":"2019","unstructured":"Zhang Y, Chen B (2019) Prognostic value of the advanced lung cancer inflammation index in patients with lung cancer: a meta-analysis. Dis Markers 2019:2513026","journal-title":"Dis Markers"},{"key":"2293_CR13","doi-asserted-by":"publisher","first-page":"3127275","DOI":"10.1155\/2020\/3127275","volume":"2020","author":"E Topkan","year":"2020","unstructured":"Topkan E et al (2020) Low advanced lung cancer inflammation index predicts poor prognosis in locally advanced nasopharyngeal carcinoma patients treated with definitive concurrent chemoradiotherapy. J Oncol 2020:3127275","journal-title":"J Oncol"},{"issue":"2","key":"2293_CR14","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1200\/JCO.2015.61.6441","volume":"34","author":"LA Renfro","year":"2016","unstructured":"Renfro LA et al (2016) Body mass index is prognostic in metastatic colorectal cancer: pooled analysis of patients from first-line clinical trials in the ARCAD database. J Clin Oncol 34(2):144\u2013150","journal-title":"J Clin Oncol"},{"issue":"3","key":"2293_CR15","doi-asserted-by":"publisher","first-page":"684","DOI":"10.1007\/s00268-010-0891-8","volume":"35","author":"AP Stillwell","year":"2011","unstructured":"Stillwell AP, Ho YH, Veitch C (2011) Systematic review of prognostic factors related to overall survival in patients with stage IV colorectal cancer and unresectable metastases. World J Surg 35(3):684\u2013692","journal-title":"World J Surg"},{"issue":"4","key":"2293_CR16","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1002\/jso.24523","volume":"115","author":"A Haram","year":"2017","unstructured":"Haram A et al (2017) The prognostic value of neutrophil-to-lymphocyte ratio in colorectal cancer: a systematic review. J Surg Oncol 115(4):470\u2013479","journal-title":"J Surg Oncol"},{"issue":"1","key":"2293_CR17","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1186\/s12885-019-5468-9","volume":"19","author":"M Shibutani","year":"2019","unstructured":"Shibutani M et al (2019) The prognostic significance of the advanced lung cancer inflammation index in patients with unresectable metastatic colorectal cancer: a retrospective study. BMC Cancer 19(1):241","journal-title":"BMC Cancer"},{"issue":"11","key":"2293_CR18","first-page":"3403","volume":"5","author":"KR Hess","year":"1999","unstructured":"Hess KR et al (1999) Classification and regression tree analysis of 1000 consecutive patients with unknown primary carcinoma. Clin Cancer Res 5(11):3403\u20133410","journal-title":"Clin Cancer Res"},{"issue":"5","key":"2293_CR19","doi-asserted-by":"publisher","first-page":"1082","DOI":"10.1002\/ijc.30527","volume":"140","author":"A Buron Pust","year":"2017","unstructured":"Buron Pust A et al (2017) Heterogeneity of colorectal cancer risk by tumour characteristics: large prospective study of UK women. Int J Cancer 140(5):1082\u20131090","journal-title":"Int J Cancer"},{"issue":"1","key":"2293_CR20","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1111\/codi.14793","volume":"22","author":"R Tokunaga","year":"2020","unstructured":"Tokunaga R et al (2020) The clinical impact of preoperative body composition differs between male and female colorectal cancer patients. Colorectal Dis 22(1):62\u201370","journal-title":"Colorectal Dis"},{"issue":"11","key":"2293_CR21","doi-asserted-by":"publisher","first-page":"e493","DOI":"10.1016\/S1470-2045(14)70263-3","volume":"15","author":"CI Diakos","year":"2014","unstructured":"Diakos CI et al (2014) Cancer-related inflammation and treatment effectiveness. Lancet Oncol 15(11):e493-503","journal-title":"Lancet Oncol"},{"issue":"4","key":"2293_CR22","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1158\/1541-7786.MCR-05-0261","volume":"4","author":"H Lu","year":"2006","unstructured":"Lu H, Ouyang W, Huang C (2006) Inflammation, a key event in cancer development. Mol Cancer Res 4(4):221\u2013233","journal-title":"Mol Cancer Res"},{"issue":"3","key":"2293_CR23","doi-asserted-by":"publisher","first-page":"529","DOI":"10.3390\/ijms20030529","volume":"20","author":"R Mizuno","year":"2019","unstructured":"Mizuno R et al (2019) The role of tumor-associated neutrophils in colorectal cancer. Int J Mol Sci 20(3):529","journal-title":"Int J Mol Sci"},{"key":"2293_CR24","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1016\/j.cyto.2017.05.024","volume":"97","author":"A Showalter","year":"2017","unstructured":"Showalter A et al (2017) Cytokines in immunogenic cell death: applications for cancer immunotherapy. Cytokine 97:123\u2013132","journal-title":"Cytokine"},{"issue":"7","key":"2293_CR25","doi-asserted-by":"publisher","first-page":"784","DOI":"10.1002\/bjs.10682","volume":"105","author":"U Nitsche","year":"2018","unstructured":"Nitsche U et al (2018) Meta-analysis of outcomes following resection of the primary tumour in patients presenting with metastatic colorectal cancer. Br J Surg 105(7):784\u2013796","journal-title":"Br J Surg"},{"issue":"1","key":"2293_CR26","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1093\/jjco\/hyz173","volume":"50","author":"K Moritani","year":"2020","unstructured":"Moritani K et al (2020) A randomized controlled trial comparing primary tumour resection plus chemotherapy with chemotherapy alone in incurable stage IV colorectal cancer: JCOG1007 (iPACS study). Jpn J Clin Oncol 50(1):89\u201393","journal-title":"Jpn J Clin Oncol"},{"key":"2293_CR27","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.ejca.2017.03.009","volume":"78","author":"R Adam","year":"2017","unstructured":"Adam R et al (2017) Resection of colorectal liver metastases after second-line chemotherapy: is it worthwhile? A LiverMetSurvey analysis of 6415 patients. Eur J Cancer 78:7\u201315","journal-title":"Eur J Cancer"},{"issue":"6","key":"2293_CR28","doi-asserted-by":"publisher","first-page":"1027","DOI":"10.1097\/01.sla.0000146145.69835.c5","volume":"240","author":"M Selzner","year":"2004","unstructured":"Selzner M et al (2004) Does the novel PET\/CT imaging modality impact on the treatment of patients with metastatic colorectal cancer of the liver? Ann Surg 240(6):1027\u201334 (discussion 1035\u20136)","journal-title":"Ann Surg"},{"key":"2293_CR29","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.suronc.2019.02.005","volume":"29","author":"DI Tsilimigras","year":"2019","unstructured":"Tsilimigras DI et al (2019) Disappearing liver metastases: a systematic review of the current evidence. Surg Oncol 29:7\u201313","journal-title":"Surg Oncol"},{"issue":"23","key":"2293_CR30","doi-asserted-by":"publisher","first-page":"4139","DOI":"10.1002\/cncr.32163","volume":"125","author":"S Piawah","year":"2019","unstructured":"Piawah S, Venook AP (2019) Targeted therapy for colorectal cancer metastases: a review of current methods of molecularly targeted therapy and the use of tumor biomarkers in the treatment of metastatic colorectal cancer. Cancer 125(23):4139\u20134147","journal-title":"Cancer"},{"key":"2293_CR31","doi-asserted-by":"publisher","first-page":"e10100","DOI":"10.7717\/peerj.10100","volume":"8","author":"H Xie","year":"2020","unstructured":"Xie H et al (2020) The advanced lung cancer inflammation index predicts short and long-term outcomes in patients with colorectal cancer following surgical resection: a retrospective study. PeerJ 8:e10100","journal-title":"PeerJ"},{"issue":"8","key":"2293_CR32","doi-asserted-by":"publisher","first-page":"1151","DOI":"10.1080\/01635581.2017.1367947","volume":"69","author":"M Mantzorou","year":"2017","unstructured":"Mantzorou M et al (2017) Clinical value of nutritional status in cancer: what is its impact and how it affects disease progression and prognosis? Nutr Cancer 69(8):1151\u20131176","journal-title":"Nutr Cancer"},{"issue":"3","key":"2293_CR33","doi-asserted-by":"publisher","first-page":"pkaa024","DOI":"10.1093\/jncics\/pkaa024","volume":"4","author":"BJ Guercio","year":"2020","unstructured":"Guercio BJ et al (2020) Body mass index and weight loss in metastatic colorectal cancer in CALGB (Alliance)\/SWOG 80405. JNCI Cancer Spectr 4(3):pkaa024","journal-title":"JNCI Cancer Spectr"},{"issue":"10","key":"2293_CR34","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1007\/s11912-016-0546-5","volume":"18","author":"IP Carneiro","year":"2016","unstructured":"Carneiro IP, Mazurak VC, Prado CM (2016) Clinical implications of sarcopenic obesity in cancer. Curr Oncol Rep 18(10):62","journal-title":"Curr Oncol Rep"},{"issue":"10","key":"2293_CR35","doi-asserted-by":"publisher","first-page":"e0164056","DOI":"10.1371\/journal.pone.0164056","volume":"11","author":"EY Kim","year":"2016","unstructured":"Kim EY et al (2016) Prognostic significance of modified advanced lung cancer inflammation index (ALI) in patients with small cell lung cancer_ comparison with original ALI. PLoS ONE 11(10):e0164056","journal-title":"PLoS ONE"},{"key":"2293_CR36","doi-asserted-by":"publisher","first-page":"8657","DOI":"10.2147\/CMAR.S211089","volume":"11","author":"J Jiang","year":"2019","unstructured":"Jiang J et al (2019) Pre-treatment inflammatory biomarkers predict early treatment response and favorable survival in patients with metastatic colorectal cancer who underwent first line cetuximab plus chemotherapy. Cancer Manag Res 11:8657\u20138668","journal-title":"Cancer Manag Res"}],"container-title":["International Journal of Clinical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10147-023-02293-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10147-023-02293-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10147-023-02293-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,6]],"date-time":"2023-03-06T06:09:45Z","timestamp":1678082985000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10147-023-02293-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,13]]},"references-count":36,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,3]]}},"alternative-id":["2293"],"URL":"https:\/\/doi.org\/10.1007\/s10147-023-02293-2","relation":{},"ISSN":["1341-9625","1437-7772"],"issn-type":[{"value":"1341-9625","type":"print"},{"value":"1437-7772","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1,13]]},"assertion":[{"value":"24 February 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 January 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 January 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no conflicts of interest to report.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}