{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T19:14:08Z","timestamp":1757618048724,"version":"3.44.0"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2025,5,12]],"date-time":"2025-05-12T00:00:00Z","timestamp":1747008000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,5,12]],"date-time":"2025-05-12T00:00:00Z","timestamp":1747008000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J Clin Oncol"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1007\/s10147-025-02787-1","type":"journal-article","created":{"date-parts":[[2025,5,12]],"date-time":"2025-05-12T13:34:03Z","timestamp":1747056843000},"page":"1545-1552","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of body mass index on D-dimer diagnostic utility for deep vein thrombosis in patients with cancer: a single-center retrospective analysis"],"prefix":"10.1007","volume":"30","author":[{"given":"Yuya","family":"Masuda","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6203-9435","authenticated-orcid":false,"given":"Tatsuya","family":"Konishi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshihiro","family":"Yakushijin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shintaro","family":"Yamanaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinji","family":"Hasebe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Yamanouchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsuto","family":"Takenaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,5,12]]},"reference":[{"key":"2787_CR1","doi-asserted-by":"publisher","first-page":"458","DOI":"10.3390\/cancers16020458","volume":"16","author":"A Dr\u0103gan","year":"2024","unstructured":"Dr\u0103gan A, Dr\u0103gan A\u015e (2024) Novel insights in venous thromboembolism risk assessment methods in ambulatory cancer patients: From the guidelines to clinical practice. Cancers (Basel) 16:458","journal-title":"Cancers (Basel)"},{"key":"2787_CR2","doi-asserted-by":"publisher","DOI":"10.1183\/16000617.0119-2018","volume":"28","author":"CJ Fernandes","year":"2019","unstructured":"Fernandes CJ, Morinaga LTK, Alves JLJ et al (2019) Cancer-associated thrombosis: the when, how and why. Eur Respir Rev 28:180119","journal-title":"Eur Respir Rev"},{"key":"2787_CR3","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2021.669288","volume":"8","author":"LH Lee","year":"2021","unstructured":"Lee LH, Nagarajan C, Tan CW et al (2021) Epidemiology of cancer-associated thrombosis in Asia: a systematic review. Front Cardiovasc Med 8:669288","journal-title":"Front Cardiovasc Med"},{"key":"2787_CR4","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1038\/s41572-022-00336-y","volume":"8","author":"AA Khorana","year":"2022","unstructured":"Khorana AA, Mackman N, Falanga A et al (2022) Cancer-associated venous thromboembolism. Nat Rev Dis Primers 8:11","journal-title":"Nat Rev Dis Primers"},{"key":"2787_CR5","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1016\/j.annonc.2022.12.014","volume":"34","author":"A Falanga","year":"2023","unstructured":"Falanga A, Ay C, Di Nisio M et al (2023) Venous thromboembolism in cancer patients: ESMO clinical practice guideline. Ann Oncol 34:452","journal-title":"Ann Oncol"},{"key":"2787_CR6","doi-asserted-by":"publisher","first-page":"684","DOI":"10.1182\/asheducation-2013.1.684","volume":"2013","author":"GC Connolly","year":"2013","unstructured":"Connolly GC, Francis CW (2013) Cancer-associated thrombosis. Hematol Am Soc Hematol Educ Program 2013:684","journal-title":"Hematol Am Soc Hematol Educ Program"},{"key":"2787_CR7","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1200\/JCO.19.01461","volume":"38","author":"NS Key","year":"2020","unstructured":"Key NS, Khorana AA, Kuderer NM et al (2020) Venous thromboembolism prophylaxis and treatment in patients with cancer: ASCO clinical practice guideline update. J Clin Oncol 38:496","journal-title":"J Clin Oncol"},{"key":"2787_CR8","doi-asserted-by":"publisher","first-page":"2926","DOI":"10.1200\/JCO.22.01542","volume":"41","author":"A Li","year":"2023","unstructured":"Li A, La J, May SB et al (2023) Derivation and validation of a clinical risk assessment model for cancer-associated thrombosis in two unique US health care systems. J Clin Oncol 41:2926","journal-title":"J Clin Oncol"},{"key":"2787_CR9","doi-asserted-by":"publisher","first-page":"1712","DOI":"10.1182\/blood-2013-04-460121","volume":"122","author":"JF Timp","year":"2013","unstructured":"Timp JF, Braekkan SK, Versteeg HH et al (2013) Epidemiology of cancer-associated venous thrombosis. Blood 122:1712","journal-title":"Blood"},{"key":"2787_CR10","doi-asserted-by":"publisher","first-page":"354","DOI":"10.3892\/etm.2024.12643","volume":"28","author":"DM Nemtut","year":"2024","unstructured":"Nemtut DM, Petreanu CA, Ulmeanu R et al (2024) Life expectancy in cancer patients with pulmonary thromboembolism: from clinical prognostic biomarkers and paraclinical investigations to therapeutic approaches. Exp Ther Med 28:354","journal-title":"Exp Ther Med"},{"key":"2787_CR11","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1016\/bs.acc.2023.02.006","volume":"114","author":"L Wauthier","year":"2023","unstructured":"Wauthier L, Favresse J, Hardy M et al (2023) D-dimer testing: a narrative review. Adv Clin Chem 114:151","journal-title":"Adv Clin Chem"},{"key":"2787_CR12","doi-asserted-by":"publisher","first-page":"1117","DOI":"10.1001\/jama.2014.2135","volume":"311","author":"M Righini","year":"2014","unstructured":"Righini M, Van Es J, Den Exter PL et al (2014) Age-adjusted D-dimer cut-off levels to rule out pulmonary embolism: the ADJUST-PE study. JAMA 311:1117","journal-title":"JAMA"},{"key":"2787_CR13","doi-asserted-by":"publisher","first-page":"1158","DOI":"10.3324\/haematol.2011.054718","volume":"97","author":"C Ay","year":"2012","unstructured":"Ay C, Dunkler D, Pirker R et al (2012) High D-dimer levels are associated with poor prognosis in cancer patients. Haematologica 97:1158","journal-title":"Haematologica"},{"key":"2787_CR14","doi-asserted-by":"publisher","DOI":"10.1111\/eci.14060","volume":"53","author":"J Gotta","year":"2023","unstructured":"Gotta J, Gruenewald LD, Eichler K et al (2023) Unveiling the diagnostic enigma of D-dimer testing in cancer patients: current evidence and areas of application. Eur J Clin Investig 53:e14060","journal-title":"Eur J Clin Investig"},{"key":"2787_CR15","doi-asserted-by":"publisher","first-page":"614","DOI":"10.1160\/TH13-12-1024","volume":"112","author":"H Robert-Ebadi","year":"2014","unstructured":"Robert-Ebadi H, Bertoletti L, Combescure C et al (2014) Effects of impaired renal function on levels and performance of D-dimer in patients with suspected pulmonary embolism. Thromb Haemost 112:614","journal-title":"Thromb Haemost"},{"key":"2787_CR16","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2018.213322","volume":"104","author":"VT Cate","year":"2019","unstructured":"Cate VT, Nagler M, Panova-Noeva M et al (2019) The diagnostic performance of renal function-adjusted D-dimer testing in individuals suspected of having venous thromboembolism. Haematologica 104:e424","journal-title":"Haematologica"},{"key":"2787_CR17","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.3324\/haematol.2024.285769","volume":"109","author":"M Franchini","year":"2024","unstructured":"Franchini M, Focosi D, Pezzo MP et al (2024) How we manage a high D-dimer. Haematologica 109:1035","journal-title":"Haematologica"},{"key":"2787_CR18","doi-asserted-by":"publisher","first-page":"162","DOI":"10.15386\/mpr-1372","volume":"93","author":"C Hotoleanu","year":"2020","unstructured":"Hotoleanu C (2020) Association between obesity and venous thromboembolism. Med Pharm Rep 93:162","journal-title":"Med Pharm Rep"},{"key":"2787_CR19","doi-asserted-by":"publisher","first-page":"3031","DOI":"10.1111\/jth.15520","volume":"19","author":"JI Weitz","year":"2021","unstructured":"Weitz JI, Farjat AE, Ageno W et al (2021) Influence of body mass index on clinical outcomes in venous thromboembolism: insights from Garfield-VTE. J Thromb Haemost 19:3031","journal-title":"J Thromb Haemost"},{"key":"2787_CR20","doi-asserted-by":"publisher","first-page":"499","DOI":"10.4236\/ojpm.2012.24069","volume":"2","author":"G Yang","year":"2012","unstructured":"Yang G, De Staercke C, Hooper WC (2012) The effects of obesity on venous thromboembolism: a review. Open J Prev Med 2:499","journal-title":"Open J Prev Med"},{"key":"2787_CR21","doi-asserted-by":"publisher","first-page":"1290","DOI":"10.3390\/medicina58091290","volume":"58","author":"P Ntinopoulou","year":"2022","unstructured":"Ntinopoulou P, Ntinopoulou E, Papathanasiou IV et al (2022) Obesity as a risk factor for venous thromboembolism recurrence: a systematic review. Medicina (Kaunas) 58:1290","journal-title":"Medicina (Kaunas)"},{"key":"2787_CR22","doi-asserted-by":"publisher","first-page":"484","DOI":"10.1200\/JCO.2005.03.8877","volume":"24","author":"AA Khorana","year":"2006","unstructured":"Khorana AA, Francis CW, Culakova E et al (2006) Thromboembolism in hospitalized neutropenic cancer patients. J Clin Oncol 24:484","journal-title":"J Clin Oncol"},{"key":"2787_CR23","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1186\/s12959-022-00442-7","volume":"20","author":"Y Li","year":"2022","unstructured":"Li Y, Liu Z, Chen C et al (2022) Risk factors and potential predictors of pulmonary embolism in cancer patients undergoing thoracic and abdominopelvic surgery: a case control study. Thromb J 20:80","journal-title":"Thromb J"},{"key":"2787_CR24","first-page":"93","volume":"67","author":"MB Amin","year":"2017","unstructured":"Amin MB, Greene FL, Edge SB et al (2017) The eighth edition AJCC cancer staging manual: continuing to build a bridge from a population-based to a more \u201cpersonalized\u201d approach to cancer staging. CA Cancer J Clin 67:93","journal-title":"CA Cancer J Clin"},{"key":"2787_CR25","unstructured":"Obesity: preventing and managing the global epidemic. Report of a WHO consultation. World Health Organ Tech Rep Ser. (2000) 894:1."},{"key":"2787_CR26","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1038\/bmt.2012.244","volume":"48","author":"Y Kanda","year":"2013","unstructured":"Kanda Y (2013) Investigation of the freely available easy-to-use software \u2018EZR\u2019 for medical statistics. Bone Marrow Transplant 48:452","journal-title":"Bone Marrow Transplant"},{"key":"2787_CR27","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2022.910770","volume":"12","author":"P Bossi","year":"2022","unstructured":"Bossi P, De Luca R, Ciani O et al (2022) Malnutrition management in oncology: an expert view on controversial issues and future perspectives. Front Oncol 12:910770","journal-title":"Front Oncol"},{"key":"2787_CR28","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2023.107074","volume":"50","author":"J Arends","year":"2024","unstructured":"Arends J (2024) Malnutrition in cancer patients: causes, consequences and treatment options. Eur J Surg Oncol 50:107074","journal-title":"Eur J Surg Oncol"},{"key":"2787_CR29","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2023.103689","volume":"28","author":"K Nishie","year":"2023","unstructured":"Nishie K, Nishie T, Sato S et al (2023) Update on the treatment of cancer cachexia. Drug Discov Today 28:103689","journal-title":"Drug Discov Today"},{"key":"2787_CR30","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1016\/S0140-6736(03)15268-3","volume":"363","author":"WHO Expert Consultation","year":"2004","unstructured":"WHO Expert Consultation (2004) Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies. Lancet 363:157","journal-title":"Lancet"},{"key":"2787_CR31","doi-asserted-by":"publisher","first-page":"751","DOI":"10.1093\/ije\/dyh163","volume":"33","author":"C Ni Mhurchu","year":"2004","unstructured":"Ni Mhurchu C, Rodgers A, Pan WH et al (2004) Body mass index and cardiovascular disease in the Asia-Pacific region: an overview of 33 cohorts involving 310 000 participants. Int J Epidemiol 33:751","journal-title":"Int J Epidemiol"},{"key":"2787_CR32","doi-asserted-by":"publisher","first-page":"dyad45","DOI":"10.1093\/ije\/dyad145","volume":"53","author":"N Yamamoto","year":"2024","unstructured":"Yamamoto N, Ejima K, Mestre LM et al (2024) Body mass index trajectories and mortality risk in Japan using a population-based prospective cohort study: the Japan Public Health center-based prospective study. Int J Epidemiol 53:dyad45","journal-title":"Int J Epidemiol"},{"key":"2787_CR33","doi-asserted-by":"publisher","first-page":"987","DOI":"10.1253\/circj.66.987","volume":"66","author":"Examination Committee of Criteria for 'Obesity Disease' in Japan; Japan Society for the Study of Obesity","year":"2002","unstructured":"Examination Committee of Criteria for \u201cObesity Disease\u201d in Japan; Japan Society for the Study of Obesity (2002) New criteria for \u201cobesity disease\u201d in Japan. Circ J 66:987","journal-title":"Circ J"},{"key":"2787_CR34","doi-asserted-by":"publisher","first-page":"1795","DOI":"10.1016\/S0140-6736(97)08140-3","volume":"350","author":"PS Wells","year":"1997","unstructured":"Wells PS, Anderson DR, Bormanis J et al (1997) Value of assessment of pretest probability of deep-vein thrombosis in clinical management. Lancet 350:1795","journal-title":"Lancet"},{"key":"2787_CR35","doi-asserted-by":"publisher","first-page":"4902","DOI":"10.1182\/blood-2007-10-116327","volume":"111","author":"AA Khorana","year":"2008","unstructured":"Khorana AA, Kuderer NM, Culakova E et al (2008) Development and validation of a predictive model for chemotherapy-associated thrombosis. Blood 111:4902","journal-title":"Blood"}],"container-title":["International Journal of Clinical Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10147-025-02787-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10147-025-02787-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10147-025-02787-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,6]],"date-time":"2025-09-06T14:27:10Z","timestamp":1757168830000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10147-025-02787-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,12]]},"references-count":35,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["2787"],"URL":"https:\/\/doi.org\/10.1007\/s10147-025-02787-1","relation":{},"ISSN":["1341-9625","1437-7772"],"issn-type":[{"type":"print","value":"1341-9625"},{"type":"electronic","value":"1437-7772"}],"subject":[],"published":{"date-parts":[[2025,5,12]]},"assertion":[{"value":"12 February 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 May 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 May 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}