{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T20:42:20Z","timestamp":1792269740319,"version":"4.4.0"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T00:00:00Z","timestamp":1792195200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T00:00:00Z","timestamp":1792195200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Takeda Pharmaceutical Company Limited","award":["Takeda Pharmaceutical Company Limited"],"award-info":[{"award-number":["Takeda Pharmaceutical Company Limited"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J Clin Oncol"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Long waiting times on chemotherapy days increase patient burden. Pre-visit blood sampling may streamline workflows; however, its real-world impact remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This prospective study collected data on waiting times for pre-visit vs same-day blood sampling in 50 cancer patients receiving chemotherapy between October 2024 and February 2025 at St. Marianna University Hospital. Pre\u2011visit and same\u2011day blood sampling was compared in the same patients across four waiting times: (i) check-in to consultation, (ii) check-in to check-out, and (iii\u2013iv) extended measures incorporating travel time. For times (iii) and (iv), travel time during pre-visit was also included. Patient and physician satisfaction and indirect costs were also evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The median waiting time from check-in to consultation was 1.8 and 2.2\u00a0h for pre-visit and same-day sampling, respectively; when chemotherapy and check-out were included (ii), total duration was similar (6.3 vs 6.3\u00a0h). Extended measures (iii\u2013iv) tended to be longer with pre-visit sampling. After excluding the two outliers, waiting time from check-in to chemotherapy was significantly shorter for pre-visit vs same-day sampling (3.3 vs 3.9\u00a0h,\n                      <jats:italic>p<\/jats:italic>\n                      =0.025). Patient satisfaction was favorable, and 24.0% of patients reported reduced burden. Indirect costs improved by approximately 1198 Japanese yen per patient, with benefits reported in approximately half of the cases. Subgroup analyses suggested greater benefits for patients living within 30\u00a0min of both pre-visit blood sampling and chemotherapy facilities.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Pre-visit blood sampling may reduce waiting time and perceived burden for selected patients, although overall time savings were modest.<\/jats:p>\n                    <jats:p>\n                      <jats:italic>Trial registration<\/jats:italic>\n                      University Hospital Medical Information Network (UMIN) Clinical Trials Registry: UMIN000055757.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s10147-026-03197-7","type":"journal-article","created":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T19:57:41Z","timestamp":1792267061000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A prospective study evaluating the impact of waiting time on blood testing and clinical workflows in cancer patients"],"prefix":"10.1007","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0163-7543","authenticated-orcid":false,"given":"Yu","family":"Sunakawa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Arai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yohei","family":"Kubota","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Nagata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Takeda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kumiko","family":"Umemoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiki","family":"Horie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoki","family":"Izawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Ogura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiyoshi","family":"Okazuka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuta","family":"Okamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshihide","family":"Hosoyamada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yumi","family":"Izumaru","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukiko","family":"Sakakibara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junpei","family":"Soeda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reo","family":"Takaku","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,10,17]]},"reference":[{"issue":"5","key":"3197_CR1","first-page":"393","volume":"20","author":"C Bleustein","year":"2014","unstructured":"Bleustein C, Rothschild DB, Valen A et al (2014) Wait times, patient satisfaction scores, and the perception of care. 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Y.K. reports research funding to institution from Astellas Pharma Inc. and lecture honoraria from Astellas Pharma Inc., Bristol\u2011Myers Squibb K.K., MSD K.K., and Taiho Pharmaceutical Co., Ltd. H.T. reports personal payment or honoraria for lectures, presentations, speakers bureaus, manuscript writing, or educational events from Bristol-Myers Squibb Japan, Guardant Health, and Daiichi Sankyo. R.T. reports consulting fees from Takeda Pharmaceutical Company Limited. K.O., Y.O., T.H., Y.I., Y.S., and J.S. are employees of Takeda Pharmaceutical Company Limited. H.A., Y.N., K.U., Y.H., N.I., and T.O. have no competing interests to declare.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study protocol was approved by the Institutional Review Board of St. Marianna University School of Medicine. The study was conducted in accordance with the study protocol, the ethical principles of the Declaration of Helsinki, and applicable ethical guidelines, with due consideration for the rights and welfare of individual participants. The study is registered in the University Hospital Medical Information Network (UMIN) Clinical Trials Registry (UMIN000055757).","order":2,"name":"Ethics","label":"Ethical approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All patients provided informed consent prior to participation in this study.","order":3,"name":"Ethics","label":"Consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":4,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}}]}}