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The study protocol was approved by the Institutional Review Board of Yamanashi Central Hospital for genetic analysis (approval no. G2018-1) and cancer registry research (approval no. C29-19).","order":2,"name":"Ethics","label":"Ethics approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Written informed consent for genetic analysis and use of biospecimens was obtained from all participants included in the molecular cohort. For the retrospective cancer registry analysis, information about the study was disclosed in an opt-out format in accordance with institutional guidelines.","order":3,"name":"Ethics","label":"Consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":4,"name":"Ethics","label":"Consent to publish","group":{"name":"EthicsHeading","label":"Declarations"}}]}}