{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T17:16:58Z","timestamp":1769966218759,"version":"3.49.0"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2015,12,12]],"date-time":"2015-12-12T00:00:00Z","timestamp":1449878400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2015,12,12]],"date-time":"2015-12-12T00:00:00Z","timestamp":1449878400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Tech Coloproctol"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Introduction<\/jats:title>\n            <jats:p>A new artificial anal sphincter, SphinKeeper<jats:sup>TM<\/jats:sup>, was devised with the aim to treat fecal incontinence (FI) by implanting specifically designed self-expandable prostheses into the intersphincteric space. Preliminary data concerning the procedure feasibility and prosthesis localization at 3\u00a0months are presented.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>SphinKeeper<jats:sup>TM<\/jats:sup> prostheses in the native state are dehydrated, thin, solid cylinder (length 29\u00a0mm, diameter 3\u00a0mm), changing their state (shorter\u2014length 23\u00a0mm, thicker\u2014diameter 7\u00a0mm\u2014and softer, with shape memory) within 48\u00a0h of contact with fluids. In this study, 10 prostheses were implanted in each patient with FI under local anesthesia and under endoanal ultrasound (EAUS) guidance, into the upper-middle intersphincteric space of the anal canal by a specifically designed delivery system. EAUS was used postoperatively to assess prostheses dislocation.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Ten patients (5 females; median age 58\u00a0years, range 20\u201375) were enrolled and treated with SphinKeeper<jats:sup>TM<\/jats:sup> implantation. Median duration of procedure (performed by endoanal ultrasound guidance) was 40\u00a0min (range 30\u201345). Neither intraoperative nor postoperative complications were reported after a 3-month follow-up. In one patient, a partial dislocation of a single prosthesis was documented by EAUS, causing anal discomfort which resolved after 1\u00a0week.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>SphinKeeper<jats:sup>TM<\/jats:sup> can be safely implanted in patients with FI of different etiology. Implantation was well tolerated with no dislodgment of implants at 3-month follow-up.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s10151-015-1396-0","type":"journal-article","created":{"date-parts":[[2015,12,12]],"date-time":"2015-12-12T03:58:25Z","timestamp":1449892705000},"page":"59-66","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":50,"title":["Implantation of SphinKeeperTM: a new artificial anal sphincter"],"prefix":"10.1007","volume":"20","author":[{"given":"C.","family":"Ratto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Donisi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Litta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Campenn\u00ec","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Parello","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2015,12,12]]},"reference":[{"key":"1396_CR1","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1097\/DCR.0000000000000397","volume":"58","author":"IM Paquette","year":"2015","unstructured":"Paquette IM, Varma MG, Kaiser AM, Steele SR, Rafferty JF (2015) The American Society of Colon and Rectal Surgeons\u2019 clinical practice guideline for the treatment of fecal incontinence. 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