{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T11:37:06Z","timestamp":1787312226903,"version":"build-2736575974"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2023,4,22]],"date-time":"2023-04-22T00:00:00Z","timestamp":1682121600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,4,22]],"date-time":"2023-04-22T00:00:00Z","timestamp":1682121600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100004593","name":"Universidad Aut\u00f3noma de Madrid","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100004593","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Tech Coloproctol"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The current monkeypox (MP) virus outbreak was declared an international emergency in July 2022. The aim of this report is to describe our initial experience with patients with MP, focusing on proctitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted an observational study between 20 May and 31 July 2022, on patients with MP at a reference tertiary center in Madrid, Spain. A descriptive analysis on MP was performed, focusing on its characteristics, symptoms, diagnosis, and outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 143 positive MP cases were diagnosed in our center; 42 of them [all male, median age 39\u00a0years (range: 22\u201357\u00a0years)] had proctitis (29.37%), and 3 patients (2.09%\/MP total cases and 7.14%\/MP proctitis) required surgical drainage of a perianal abscess.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>General and digestive surgeons must be aware of the presence of proctological impairment and complications due to MP virus.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s10151-023-02782-6","type":"journal-article","created":{"date-parts":[[2023,4,22]],"date-time":"2023-04-22T03:02:14Z","timestamp":1682132534000},"page":"1211-1218","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Proctitis in patients with monkeypox infection: a single-center analysis of 42 consecutive cases from a multidisciplinary observational study on monkeypox proctitis"],"prefix":"10.1007","volume":"27","author":[{"given":"J.","family":"Guevara-Mart\u00ednez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F. Prieto","family":"La-Noire","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Arteaga-Asensio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Pascual-Miguela\u00f1ez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Moraes Souza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Quiles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Montes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Fondevila","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8356-4658","authenticated-orcid":false,"given":"M.","family":"\u00c1lvarez-Gallego","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Monkeypox multidisciplinary collaboration group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Sendagorta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia","family":"Gonzalez-Alcolea","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camilo","family":"Zapata-Syro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfredo","family":"Maldonado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia Sanz","family":"Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. L.","family":"Marijuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,4,22]]},"reference":[{"issue":"23","key":"2782_CR1","doi-asserted-by":"publisher","first-page":"2278","DOI":"10.1001\/jama.2022.9499","volume":"327","author":"E Harris","year":"2022","unstructured":"Harris E (2022) What to know about monkeypox. JAMA 327(23):2278\u20132279. https:\/\/doi.org\/10.1001\/jama.2022.9499","journal-title":"JAMA"},{"issue":"377","key":"2782_CR2","doi-asserted-by":"publisher","first-page":"o1321","DOI":"10.1136\/bmj.o1321","volume":"25","author":"E Nakoune","year":"2022","unstructured":"Nakoune E, Olliaro P (2022) Waking up to monkeypox. BMJ. 25(377):o1321. https:\/\/doi.org\/10.1136\/bmj.o1321","journal-title":"BMJ."},{"issue":"8","key":"2782_CR3","doi-asserted-by":"publisher","first-page":"1153","DOI":"10.1016\/S1473-3099(22)00228-6","volume":"22","author":"H Adler","year":"2022","unstructured":"Adler H, Gould S, Hine P, Snell LB, Wong W, Houlihan CF, Osborne JC, Rampling T, Beadsworth MB, Duncan CJ, Dunning J, Fletcher TE, Hunter ER, Jacobs M, Khoo SH, Newsholme W, Porter D, Porter RJ, Ratcliffe L, Schmid ML, Semple MG, Tunbridge AJ, Wingfield T, Price NM (2022) NHS England high consequence infectious diseases (Airborne) network clinical features and management of human monkeypox: a retrospective observational study in the UK. Lancet Infect Dis. 22(8):1153\u20131162. https:\/\/doi.org\/10.1016\/S1473-3099(22)00228-6. (Epub 2022 May 24. Erratum in: Lancet Infect Dis. 2022 Jul;22(7):e177. Erratum in: Lancet Infect Dis. 2022 Jul;22(7):e177. PMID: 35623380; PMCID: PMC9300470)","journal-title":"Lancet Infect Dis."},{"key":"2782_CR4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2207323","author":"JP Thornhill","year":"2022","unstructured":"Thornhill JP, Barkati S, Walmsley S, Rockstroh J, Antinori A, Harrison LB, Palich R, Nori A, Reeves I, Habibi MS, Apea V, Boesecke C, Vandekerckhove L, Yakubovsky M, Sendagorta E, Blanco JL, Florence E, Moschese D, Maltez FM, Goorhuis A, Pourcher V, Migaud P, Noe S, Pintado C, Maggi F, Hansen AE, Hoffmann C, Lezama JI, Mussini C, Cattelan A, Makofane K, Tan D, Nozza S, Nemeth J, Klein MB, Orkin CM, SHARE-net Clinical Group (2022) Monkeypox virus infection in humans across 16 countries - April-June 2022. N Engl J Med. https:\/\/doi.org\/10.1056\/NEJMoa2207323. (Epub ahead of print. PMID: 35866746)","journal-title":"N Engl J Med"},{"key":"2782_CR5","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.21790","author":"A Catal\u00e0","year":"2022","unstructured":"Catal\u00e0 A, Clavo Escribano P, Riera J, Mart\u00edn-Ezquerra G, Fernandez-Gonzalez P, Revelles Pe\u00f1as L, Sim\u00f3n Gozalbo A, Rodr\u00edguez-Cuadrado FJ, Guilera Castells V, De la Torre Gomar FJ, Comuni\u00f3n Artieda A, Fuertes de Vega L, Blanco JL, Puig S, Garc\u00eda Mi\u00f1arro \u00c1M, Fiz Benito E, Mu\u00f1oz-Santos C, Repiso-Jim\u00e9nez JB, Ceballos-Rodriguez C, Garc\u00eda Rodr\u00edguez V, Casta\u00f1o Fern\u00e1ndez JL, S\u00e1nchez-Guti\u00e9rrez I, Calvo L\u00f3pez R, Berna-Rico E, de Nicol\u00e1s-Ruanes B, Corella Vicente F, Tar\u00edn Vicente EJ, De Fern\u00e1ndez Fuente L, Riera-Mart\u00ed N, Descalzo-Gallego MA, Grau-Perez M, Garc\u00eda-Doval I, Fuertes I (2022) Monkeypox outbreak in Spain: clinical and epidemiological findings in a prospective cross-sectional study of 185 cases. Br J Dermatol. https:\/\/doi.org\/10.1111\/bjd.21790","journal-title":"Br J Dermatol"},{"key":"2782_CR6","volume-title":"In: StatPearls [Internet]","author":"MJ Moore","year":"2022","unstructured":"Moore MJ, Rathish B, Monkeypox Zahra F (2022) In: StatPearls [Internet]. StatPearls Publishing, Treasure Island (FL)"},{"key":"2782_CR7","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1111\/j.1600-065X.2008.00691.x.","volume":"225","author":"JR Weaver","year":"2008","unstructured":"Weaver JR, Isaacs SN (2008) Monkeypox virus and insights into its immunomodulatory proteins. Immunol Rev 225:96\u2013113. https:\/\/doi.org\/10.1111\/j.1600-065X.2008.00691.x. (PMID:18837778;PMCID:PMC2567051)","journal-title":"Immunol Rev"},{"issue":"7","key":"2782_CR8","doi-asserted-by":"publisher","first-page":"1434","DOI":"10.1111\/jdv.17269","volume":"35","author":"HJC de Vries","year":"2021","unstructured":"de Vries HJC, Nori AV, Kiellberg Larsen H, Kreuter A, Padovese V, Pallawela S, Vall-Mayans M, Ross J (2021) 2021 European Guideline on the management of proctitis, proctocolitis and enteritis caused by sexually transmissible pathogens. J Eur Acad Dermatol Venereol 35(7):1434\u20131443. https:\/\/doi.org\/10.1111\/jdv.17269. (Epub 2021 May 31 PMID: 34057249)","journal-title":"J Eur Acad Dermatol Venereol"},{"issue":"7","key":"2782_CR9","first-page":"e26531","volume":"14","author":"J Kaler","year":"2022","unstructured":"Kaler J, Hussain A, Flores G, Kheiri S, Desrosiers D (2022) Monkeypox: a comprehensive review of transmission, pathogenesis, and manifestation. Cureus 14(7):e26531","journal-title":"Cureus"},{"key":"2782_CR10","unstructured":"Informe de situaci\u00f3n de Monkeypox en Espa\u00f1a y otros pa\u00edses no end\u00e9micos 05.08.2022."},{"key":"2782_CR11","unstructured":"https:\/\/www.sanidad.gob.es\/profesionales\/saludPublica\/ccayes\/alertasActual\/alertaMonkeypox\/docs\/Informe_de_situacion_MPX_20220805.pdf."},{"key":"2782_CR12","doi-asserted-by":"publisher","unstructured":"Yakubovsky M, Shasha D, Reich S, et\u00a0al. (2022) Monkeypox presenting as proctitis in men who have sex with men [published online ahead of print]. Clin Infect Dis. https:\/\/doi.org\/10.1093\/cid\/ciac737","DOI":"10.1093\/cid\/ciac737"},{"key":"2782_CR13","doi-asserted-by":"publisher","unstructured":"Ramai D, Dubroff J, Walker MJ, (2022) Severe proctitis associated with monkeypox virus [published online ahead of print 2022 Nov 11]. Am J Gastroenterol. https:\/\/doi.org\/10.14309\/ajg.0000000000002069","DOI":"10.14309\/ajg.0000000000002069"},{"key":"2782_CR14","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.27931","author":"NL Bragazzi","year":"2022","unstructured":"Bragazzi NL, Kong JD, Mahroum N, Tsigalou C, Khamisy-Farah R, Converti M, Wu J (2022) Epidemiological trends and clinical features of the ongoing monkeypox epidemic: a preliminary pooled data analysis and literature review. J Med Virol. https:\/\/doi.org\/10.1002\/jmv.27931. (Epub ahead of print. PMID: 35692117)","journal-title":"J Med Virol"},{"key":"2782_CR15","doi-asserted-by":"publisher","DOI":"10.3701\/req\/059.2022","author":"MC Mart\u00edn-Delgado","year":"2022","unstructured":"Mart\u00edn-Delgado MC, Mart\u00edn S\u00e1nchez FJ, Mart\u00ednez-Sell\u00e9s M, Molero Garc\u00eda JM, Moreno Guill\u00e9n S, Rodr\u00edguez-Artalejo FJ, Ruiz-Galiana J, Cant\u00f3n R, De Lucas Ramos P, Garc\u00eda-Botella A, Garc\u00eda-Lled\u00f3 A, Hern\u00e1ndez-Sampelayo T, G\u00f3mez-Pav\u00f3n J, Gonz\u00e1lez Del Castillo J, Mu\u00f1oz P, Valerio M, Catal\u00e1n P, Burillo A, Cobo A, Alcam\u00ed A, Bouza E (2022) Monkeypox in humans: a new outbreak. Rev Esp Quimioter. https:\/\/doi.org\/10.3701\/req\/059.2022. (Epub ahead of print. PMID: 35785957)","journal-title":"Rev Esp Quimioter"},{"key":"2782_CR16","doi-asserted-by":"publisher","unstructured":"Dom\u00ednguez Alvarado GA, Rativa Hern\u00e1ndez JA, Hortua Moreno AF, et\u00a0al. (2022) Monkeypox outbreak, will it affect surgery services? - Correspondence [published online ahead of print 2022 Aug 2]. Int J Surg https:\/\/doi.org\/10.1016\/j.ijsu.2022.106809","DOI":"10.1016\/j.ijsu.2022.106809"},{"key":"2782_CR17","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2022.27.26.2200477","author":"D N\u00f6rz","year":"2022","unstructured":"N\u00f6rz D, Pfefferle S, Brehm TT, Franke G, Grewe I, Knobling B, Aepfelbacher M, Huber S, Klupp EM, Jordan S, Addo MM, Schulze Zur Wiesch J, Schmiedel S, L\u00fctgehetmann M, Knobloch JK (2022) Evidence of surface contamination in hospital rooms occupied by patients infected with monkeypox. Germany, Euro Surveill. https:\/\/doi.org\/10.2807\/1560-7917.ES.2022.27.26.2200477","journal-title":"Germany, Euro Surveill"},{"key":"2782_CR18","doi-asserted-by":"publisher","unstructured":"Eloy Jos\u00e9 Tar\u00edn-Vicente, Andrea Alemany, Manuel Agud-Dios, Maria Ubals, Clara Su\u00f1er, Andr\u00e9s Ant\u00f3n, Maider Arando, Jorge Arroyo-Andr\u00e9s, Lorena Calder\u00f3n-Lozano, Cristina Casa\u00f1, Jos\u00e9 Miguel Cabrera, Pep Coll, Vicente Descalzo, Mar\u00eda Dolores Folgueira, Jorge N Garc\u00eda-P\u00e9rez, Elena Gil-Cruz, Borja Gonz\u00e1lez-Rodr\u00edguez, Christian Guti\u00e9rrez-Collar, \u00c1gueda Hern\u00e1ndez-Rodr\u00edguez, Paula L\u00f3pez-Roa, Mar\u00eda de los \u00c1ngeles Mel\u00e9ndez, Julia Montero-Men\u00e1rguez, Irene Mu\u00f1oz-Gallego, Sara Isabel Palencia-P\u00e9rez, Roger Paredes, Alfredo P\u00e9rez-Rivilla, Mar\u00eda Pi\u00f1ana, Nuria Prat, A\u00edda Ramirez, \u00c1ngel Rivero, Carmen Alejandra Rubio-Mu\u00f1iz, Mart\u00ed Vall, Kevin Stephen Acosta-Vel\u00e1squez, An Wang, Cristina Galv\u00e1n-Casas*, Michael Marks*, Pablo L Ortiz-Romero*, Oriol Mitj\u00e0. (2022) Clinical presentation and virological assessment of confirmed human monkeypox virus cases in Spain: a prospective observational cohort study. Lancet https:\/\/doi.org\/10.1016\/S0140-6736(22)01436-2.","DOI":"10.1016\/S0140-6736(22)01436-2"},{"issue":"22","key":"2782_CR19","doi-asserted-by":"publisher","first-page":"2200421","DOI":"10.2807\/1560-7917.ES.2022.27.22.2200421","volume":"27","author":"A Antinori","year":"2022","unstructured":"Antinori A, Mazzotta V, Vita S et\u00a0al. (2022) Epidemiological, clinical and virological characteristics of four cases of monkeypox support transmission through sexual contact, Italy, May 2022. Euro Surveill 27(22):2200421. https:\/\/doi.org\/10.2807\/1560-7917.ES.2022.27.22.2200421","journal-title":"Euro Surveill"},{"key":"2782_CR20","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/j.clinimag.2022.10.008","volume":"92","author":"MD Messina","year":"2022","unstructured":"Messina MD, Wolf EL, Kanmaniraja D, Alpert PL, Ricci ZJ (2022) Imaging features of anorectal proctitis in monkeypox infection. Clin Imaging 92:109\u2013111. https:\/\/doi.org\/10.1016\/j.clinimag.2022.10.008","journal-title":"Clin Imaging"},{"key":"2782_CR21","doi-asserted-by":"publisher","DOI":"10.1177\/09564624221114191","author":"Y Ortiz-Mart\u00ednez","year":"2022","unstructured":"Ortiz-Mart\u00ednez Y, Zambrano-Sanchez G, Rodr\u00edguez-Morales AJ (2022) Monkeypox and HIV\/AIDS: when the outbreak faces the epidemic. Int J STD AIDS. https:\/\/doi.org\/10.1177\/09564624221114191","journal-title":"Int J STD AIDS"},{"key":"2782_CR22","unstructured":"WHO. Disease outbreak news; multi-country monkeypox outbreak in non-endemic countries. World Health Organization; 2022."},{"key":"2782_CR23","unstructured":"https:\/\/ www.who.int\/emergencies\/disease-outbreak-news\/item\/2022-DON385"},{"issue":"7","key":"2782_CR24","doi-asserted-by":"publisher","first-page":"604","DOI":"10.1111\/tmi.13785","volume":"27","author":"TP Velavan","year":"2022","unstructured":"Velavan TP, Meyer CG (2022) Monkeypox 2022 outbreak: an update. Trop Med Int Health 27(7):604\u2013605. https:\/\/doi.org\/10.1111\/tmi.13785","journal-title":"Trop Med Int Health"},{"key":"2782_CR25","unstructured":"Actualizaci\u00f3n de recomendaciones de vacunaci\u00f3n en el brote actual de viruela del mono. 12 de julio 2022. https:\/\/www.sanidad.gob.es\/profesionales\/saludPublica\/prevPromocion\/vacunaciones\/MonkeyPox\/docs\/Actualizacion_Propuesta_vacunacion_Monkeypox.pdf"},{"issue":"9","key":"2782_CR26","doi-asserted-by":"publisher","first-page":"957","DOI":"10.1007\/s40265-022-01742-y","volume":"82","author":"JG Rizk","year":"2022","unstructured":"Rizk JG, Lippi G, Henry BM, Forthal DN, Rizk Y (2022) Prevention and treatment of monkeypox. Drugs 82(9):957\u2013963. https:\/\/doi.org\/10.1007\/s40265-022-01742-y","journal-title":"Drugs"},{"key":"2782_CR27","doi-asserted-by":"publisher","unstructured":"Siegrist EA, Sassine J, (2022) Antivirals with activity against monkeypox: a clinically oriented review [published online ahead of print, 2022 Jul 29]. Clin Infect Dis https:\/\/doi.org\/10.1093\/cid\/ciac622","DOI":"10.1093\/cid\/ciac622"}],"container-title":["Techniques in Coloproctology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10151-023-02782-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10151-023-02782-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10151-023-02782-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,10]],"date-time":"2023-11-10T06:06:44Z","timestamp":1699596404000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10151-023-02782-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,22]]},"references-count":27,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2023,12]]}},"alternative-id":["2782"],"URL":"https:\/\/doi.org\/10.1007\/s10151-023-02782-6","relation":{},"ISSN":["1123-6337","1128-045X"],"issn-type":[{"value":"1123-6337","type":"print"},{"value":"1128-045X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,22]]},"assertion":[{"value":"19 November 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 March 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 April 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have declared no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Approved by the ethical committee of Hospital Universitario La Paz (Internal 2022.185, HULP: PI 5296). Patients were included in compliance with the ethical committee regulations of the Hospital Universitario La Paz (Internal 2022.185, HULP: PI 5296), providing informed consent to include their data in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval and Informed Consent"}}]}}