{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T22:02:47Z","timestamp":1790373767346,"version":"4.1.0"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T00:00:00Z","timestamp":1765152000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T00:00:00Z","timestamp":1765152000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Tech Coloproctol"],"published-print":{"date-parts":[[2026,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Limited data exists in literature regarding concomitant ventral rectopexy (VRP) and sacrocolpo\/hysteropexy (SCP\/SHP), with existing studies being predominantly retrospective. The aim of this meta-analysis is to assess the anatomical and functional outcomes of combined VRP and SCP\/SHP for the treatment of multicompartmental pelvic organ prolapse (POP).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We performed systematic research and meta-analysis from PubMed\/MEDLINE and EMBASE, according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines, until 15 January 2025. Women submitted to VRP with SCP\/SHP were included. Improvement of anorectal symptoms were evaluated. Postoperative anatomical relapse was reported. Re-operation rates were evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Six articles were included. Constipation\/obstructed defecation syndrome (ODS) [odds ratio (OR) 0.26, 95% CI 0.10\u20130.68;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.006 (\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      test 81%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.56)] and of anal\/fecal incontinence (AI\/FI) rates [OR 0.09, 95% CI 0.03\u20130.30;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.0001 (\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      test 70%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.04)] significantly improved after combined VRP and SCP\/SHP. The proportion metanalysis of four included studies reported a subjective POP recurrence rate of 7% (95% CI 1\u201313%;\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      test 82.9%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). The proportion metanalysis of five included studies for objective POP recurrence was 5% (95% CI 1\u20139%;\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      test 56.9%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.041). No serious adverse events were reported.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>VRP combined with SCP\/SHP has been shown to be safe and effective for women with multicompartment POP, providing optimal anatomical and functional outcomes. Larger, long-term, prospective-controlled studies are needed to confirm these results.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s10151-025-03236-x","type":"journal-article","created":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T12:14:39Z","timestamp":1765196079000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Anatomical and functional outcomes of combined ventral rectopexy and sacrocolpo\/hysteropexy for multicompartment pelvic organ prolapse: a systematic review and meta-analysis"],"prefix":"10.1007","volume":"30","author":[{"given":"Alessandro Ferdinando","family":"Ruffolo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomaso","family":"Melocchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chryst\u00e8le","family":"Rubod","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yohan","family":"Kerbage","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Campagna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Mastrovito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfredo","family":"Ercoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Panico","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Cosson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marine","family":"Lallemant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,12,8]]},"reference":[{"issue":"5","key":"3236_CR1","doi-asserted-by":"publisher","first-page":"1488","DOI":"10.1016\/j.ajog.2005.02.028","volume":"192","author":"JO DeLancey","year":"2005","unstructured":"DeLancey JO (2005) The hidden epidemic of pelvic floor dysfunction: achievable goals for improved prevention and treatment. 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