{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T14:10:49Z","timestamp":1768486249739,"version":"3.49.0"},"reference-count":26,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2004,1,1]],"date-time":"2004-01-01T00:00:00Z","timestamp":1072915200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2004,1,1]],"date-time":"2004-01-01T00:00:00Z","timestamp":1072915200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jiac-j.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Infection and Chemotherapy"],"published-print":{"date-parts":[[2004]]},"DOI":"10.1007\/s10156-004-0326-2","type":"journal-article","created":{"date-parts":[[2004,9,8]],"date-time":"2004-09-08T10:53:49Z","timestamp":1094640829000},"page":"212-215","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Changes of antimicrobial resistance and extended-spectrum \u03b2-lactamase production in Klebsiella spp. strains"],"prefix":"10.1016","volume":"10","author":[{"given":"Jaroslav","family":"Timko","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1007\/s10156-004-0326-2_bib0005","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1128\/AAC.39.6.1211","article-title":"Afunctional classification scheme for \u03b2-lactamases and its correlation with molecular structures","volume":"39","author":"Bush","year":"1995","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1007\/s10156-004-0326-2_bib0010","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1128\/CMR.8.4.557","article-title":"\u03b2-Lactamases in laboratory and clinical resistance","volume":"8","author":"Livermore","year":"1995","journal-title":"Clin Microbiol Rev"},{"issue":"Suppl D","key":"10.1007\/s10156-004-0326-2_bib0015","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1093\/jac\/41.suppl_4.25","article-title":"\u03b2-Lactamase-mediated resistance and opportunities for its control","volume":"41","author":"Livermore","year":"1998","journal-title":"J Antimicrob Chemother"},{"key":"10.1007\/s10156-004-0326-2_bib0020","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1128\/JCM.38.2.542-546.2000","article-title":"Detection of extended-spectrum \u03b2-lactamases in clinical isolates of Enterobacter cloacae and Enterobacter aerogenes","volume":"38","author":"Tzelepi","year":"2000","journal-title":"J Clin Microbiol"},{"issue":"Suppl 2","key":"10.1007\/s10156-004-0326-2_bib0025","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1046\/j.1469-0691.2000.00002.x","article-title":"Extended-spectrum \u03b2-lactamases: how big is the problem?","volume":"6","author":"Rahal","year":"2000","journal-title":"Clin Microbiol Infect"},{"key":"10.1007\/s10156-004-0326-2_bib0030","doi-asserted-by":"crossref","first-page":"1936","DOI":"10.1128\/AAC.44.7.1936-1942.2000","article-title":"A novel CTX-M \u03b2-lactamase (CTX-M-8) in cefotaximeresistant Enterobacteriaceae isolated in Brazil","volume":"44","author":"Bonnet","year":"2000","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1007\/s10156-004-0326-2_bib0035","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1093\/jac\/45.2.183","article-title":"Antimicrobial resistance amongst Klebsiella spp. from intensive care units in southern and western Europe in 1997-1998","volume":"45","author":"Babini","year":"2000","journal-title":"J Antimicrob Chemother"},{"key":"10.1007\/s10156-004-0326-2_bib0040","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/S0891-5520(05)70249-X","article-title":"Pathogens resistant to antimicrobial agents Epidemiology, molecular mechanisms, and clinical management","volume":"14","author":"Kaye","year":"2000","journal-title":"Infect Dis Clin N Am"},{"issue":"1","key":"10.1007\/s10156-004-0326-2_bib0045","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1179\/joc.2002.14.1.25","article-title":"Antimicrobial resistance in gram-negative isolates from European intensive care units: data from the Meropenem Yearly Susceptibility Test Information Collection (MYSTIC) programme","volume":"14","author":"Garcia-Rodriguez","year":"2002","journal-title":"J Chemother"},{"key":"10.1007\/s10156-004-0326-2_bib0050","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1093\/jac\/46.suppl_2.9","article-title":"MYSTIC (Meropenem yearly susceptibility test information collection): a global overview","volume":"42","author":"Turner","year":"2000","journal-title":"J Antimicrob Chemother"},{"issue":"Suppl 2","key":"10.1007\/s10156-004-0326-2_bib0055","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1086\/320181","article-title":"Worldwide prevalence of antimicrobial resistance in Streptococcus pneumoniae Haemophilus influenzae and Moraxella catarrhalis in the SENTRY Antimicrobial Resistance Surveillance Program, 1997-99","volume":"32","author":"Hoban","year":"2001","journal-title":"Clin Infect Dis"},{"key":"10.1007\/s10156-004-0326-2_bib0060","doi-asserted-by":"crossref","first-page":"1762","DOI":"10.1128\/AAC.42.7.1762","article-title":"Bacterial pathogens isolated from patients with bloodstream infections: frequency of occurrence and antimicrobial susceptibility patterns from the SENTRY antimicrobial surveillance program (United States and Canada 1997)","volume":"42","author":"Pfaller","year":"1998","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1007\/s10156-004-0326-2_bib0065","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1086\/514953","article-title":"Prevalence of antimicrobial resistance among respiratory tract isolates of S. pneumoniae in North America: 1997 results from the SENTRY antimicrobial surveillance program","volume":"27","author":"Doern","year":"1998","journal-title":"Clin Infect Dis"},{"key":"10.1007\/s10156-004-0326-2_bib0070","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1093\/jac\/38.3.409","article-title":"Antibiotic resistance and production of extended-spectrum beta-lactamases amongst Klebsiella spp. from intensive care units in Europe","volume":"38","author":"Livermore","year":"1996","journal-title":"J Antimicrob Chemother"},{"issue":"4","key":"10.1007\/s10156-004-0326-2_bib0075","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1093\/jac\/49.4.651","article-title":"Evaluation of MIDITECH automated colorimetric MIC reading for antimicrobial susceptibility testing","volume":"49","author":"Gattringer","year":"2002","journal-title":"J Antimicrob Chemother"},{"issue":"4","key":"10.1007\/s10156-004-0326-2_bib0080","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1093\/clinids\/10.4.867","article-title":"Extended broadspectrum beta-lactamases conferring transferable resistance to newer beta-lactam agents in Enterobacteriaceae: hospital prevalence and susceptibility patterns","volume":"10","author":"Jarlier","year":"1988","journal-title":"Rev Infect Dis"},{"key":"10.1007\/s10156-004-0326-2_bib0085","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/S0749-0704(05)70392-4","article-title":"Antibiotic resistance problems in the critical care unit","volume":"14","author":"Mainardi","year":"1998","journal-title":"Crit Care Clin"},{"issue":"4","key":"10.1007\/s10156-004-0326-2_bib0090","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1128\/CMR.11.4.589","article-title":"Klebsiella spp. as nosocomial pathogens: epidemiology, taxonomy, typing methods, and pathogenicity factors","volume":"11","author":"Podschun","year":"1998","journal-title":"Clin Microbiol Rev"},{"issue":"1","key":"10.1007\/s10156-004-0326-2_bib0095","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1055\/s-2003-37923","article-title":"Global epidemiology of antimicrobial resistance among community-acquired and nosocomial pathogens: afive-year summary from the SENTRY antimicrobial surveillance program (1997-2001)","volume":"24","author":"Jones","year":"2003","journal-title":"Semin Respir Crit Care Med"},{"key":"10.1007\/s10156-004-0326-2_bib0100","first-page":"98","article-title":"\u010cerm\u00e1k P. Klinicko-mikrobiologick\u00e9 podklady racion\u00e1ln\u00ed antibiotick\u00e9 l\u00e9\u010dby","author":"Kol\u00e1\u017e","year":"2002","journal-title":"Prague: Trios"},{"key":"10.1007\/s10156-004-0326-2_bib0105","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/S0140-6736(05)79618-5","article-title":"Local surveillance of antimicrobial resistance","volume":"352","author":"Wise","year":"1998","journal-title":"Lancet"},{"issue":"6","key":"10.1007\/s10156-004-0326-2_bib0110","doi-asserted-by":"crossref","first-page":"2206","DOI":"10.1128\/JCM.39.6.2206-2212.2001","article-title":"Outcome of cephalosporin treatment for serious infections due to apparently susceptible organisms producing extended-spectrum beta-lactamases: implications for the clinical microbiology laboratory","volume":"39","author":"Paterson","year":"2001","journal-title":"J Clin Microbiol"},{"key":"10.1007\/s10156-004-0326-2_bib0115","article-title":"The problem of ESBL producers \u2013 a worldwide survey into physician awareness and perception. Program and abstracts of the 42nd Interscience Conference on Antimicrobial Agents and Chemotherapy September 27-30","author":"Goossens","year":"2002","journal-title":"San Diego CA"},{"issue":"suppl 2","key":"10.1007\/s10156-004-0326-2_bib0120","doi-asserted-by":"crossref","first-page":"S94","DOI":"10.1086\/320182","article-title":"Variations in the prevalence of strains expressing an extended-spectrum betalactamase phenotype and characterization of isolates from Europe, the Americas, and the Western Pacific region","volume":"15","author":"Winokur","year":"2001","journal-title":"Clin Infect Dis"},{"key":"10.1007\/s10156-004-0326-2_bib0125","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1128\/AAC.42.1.53","article-title":"Epidemiology and successful control of a large outbreak due to Klebsiella pneumoniae isolates producing extended-spectrum betalactamases","volume":"42","author":"Pena","year":"1998","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1007\/s10156-004-0326-2_bib0130","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1164\/ajrccm.162.3.9905050","article-title":"Rotation and restricted use of antibiotics in a medical intensive care unit: impact on the incidence of ventilator-associated pneumonia caused by antibioticresistant gram-negative bacteria","volume":"162","author":"Gruson","year":"2000","journal-title":"Am J Respir Crit Care Med"}],"container-title":["Journal of Infection and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1341321X04710521?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1341321X04710521?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.springerlink.com\/index\/pdf\/10.1007\/s10156-004-0326-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T18:43:44Z","timestamp":1761158624000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1341321X04710521"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004]]},"references-count":26,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2004]]}},"alternative-id":["S1341321X04710521"],"URL":"https:\/\/doi.org\/10.1007\/s10156-004-0326-2","relation":{},"ISSN":["1341-321X"],"issn-type":[{"value":"1341-321X","type":"print"}],"subject":[],"published":{"date-parts":[[2004]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Changes of antimicrobial resistance and extended-spectrum \u03b2-lactamase production in Klebsiella spp. strains","name":"articletitle","label":"Article Title"},{"value":"Journal of Infection and Chemotherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1007\/s10156-004-0326-2","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2004 Japanese Society of Chemotherapy and the Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}