{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T01:27:20Z","timestamp":1761182840355,"version":"build-2065373602"},"reference-count":22,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jiac-j.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Infection and Chemotherapy"],"published-print":{"date-parts":[[2009]]},"DOI":"10.1007\/s10156-008-0656-6","type":"journal-article","created":{"date-parts":[[2009,3,11]],"date-time":"2009-03-11T06:23:06Z","timestamp":1236752586000},"page":"13-17","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Monte Carlo simulation for evaluation of the efficacy of carbapenems and new quinolones against ESBL-producing Escherichia coli"],"prefix":"10.1016","volume":"15","author":[{"given":"Tatsuya","family":"Nakamura","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hakuo","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chihiro","family":"Shimizu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mayumi","family":"Kasahara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuyuki","family":"Okuda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiyo","family":"Nakata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroko","family":"Fujimoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroe","family":"Okura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatsuya","family":"Nakamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaru","family":"Komatsu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kouichi","family":"Shimakawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noriyuki","family":"Sueyoshi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshiro","family":"Ura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaori","family":"Satoh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiro","family":"Toyokawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasunao","family":"Wada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamaki","family":"Orita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomomi","family":"Kofuku","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsutoshi","family":"Yamasaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masako","family":"Sakamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hisaaki","family":"Nishio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shohiro","family":"Kinoshita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1007\/s10156-008-0656-6_bib0005","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1128\/AAC.39.6.1211","article-title":"A functional classification scheme for beta-lactamases and its correlation with molecular structure","volume":"39","author":"Bush","year":"1995","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1007\/s10156-008-0656-6_bib0010","doi-asserted-by":"crossref","first-page":"26","DOI":"10.7326\/0003-4819-140-1-200401060-00008","article-title":"International prospective study of Klebsiella pneumoniae bacteremia: implications of extended-spectrum betalactamase production in nosocomial infections","volume":"140","author":"Paterson","year":"2004","journal-title":"Ann Intern Med"},{"key":"10.1007\/s10156-008-0656-6_bib0015","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1086\/320182","article-title":"Variations in the prevalence of strains expressing an extended-spectrum betalactamase phenotype and characterization of isolates from Europe, the Americas, and the Western Pacific region","volume":"32","author":"Winokur","year":"2001","journal-title":"Clin Infect Dis"},{"key":"10.1007\/s10156-008-0656-6_bib0020","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1001\/jama.281.6.517","article-title":"Multiple antibiotic-resistant Klebsiella and Escherichia coli in nursing homes","volume":"281","author":"Wiener","year":"1999","journal-title":"JAMA"},{"key":"10.1007\/s10156-008-0656-6_bib0025","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s10096-003-1084-2","article-title":"Risk factors for the development of extended-spectrum betalactamase-producing bacteria in nonhospitalized patients","volume":"23","author":"Colodner","year":"2004","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1007\/s10156-008-0656-6_bib0030","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1086\/421094","article-title":"Populationbased laboratory surveillance for Escherichia coli-producing extended-spectrum beta-lactamases: importance of community isolates with blaCTX-M genes","volume":"38","author":"Pitout","year":"2004","journal-title":"Clin Infect Dis"},{"key":"10.1007\/s10156-008-0656-6_bib0035","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1086\/516284","article-title":"Pharmacokinetic\/pharmacodynamic parameters: rationale for antibacterial dosing of mice and men","volume":"26","author":"Craig","year":"1998","journal-title":"Clin Infect Dis"},{"key":"10.1007\/s10156-008-0656-6_bib0040","first-page":"104","article-title":"Phase I study of doripenem, a new carbapenem antibiotic for injection in healthy volunteers","volume":"53","author":"Nakashima","year":"2005","journal-title":"Chemotherapy"},{"issue":"S-4","key":"10.1007\/s10156-008-0656-6_bib0045","first-page":"277","article-title":"Pharmacokinetic study on biapenem","volume":"42","author":"Saito","year":"1994","journal-title":"Chemotherapy"},{"issue":"S-4","key":"10.1007\/s10156-008-0656-6_bib0050","first-page":"379","article-title":"Studies on imipenem\/cilastatin sodium (MK-0787\/MK-0791)","volume":"33","author":"Saito","year":"1985","journal-title":"Chemotherapy"},{"issue":"S-1","key":"10.1007\/s10156-008-0656-6_bib0055","first-page":"276","article-title":"Pharmacokinetic study on meropenem","volume":"40","author":"Saito","year":"1992","journal-title":"Chemotherapy"},{"issue":"S-7","key":"10.1007\/s10156-008-0656-6_bib0060","first-page":"140","article-title":"Phase I study with BAY o 9867(cipro-floxacin)","volume":"33","author":"Kobayashi","year":"1985","journal-title":"Chemotherapy"},{"key":"10.1007\/s10156-008-0656-6_bib0065","first-page":"175","article-title":"Phase 1 study of gatifloxacin, new quinolone","volume":"48","author":"Nakajima","year":"1999","journal-title":"Chemotherapy"},{"key":"10.1007\/s10156-008-0656-6_bib0070","first-page":"175","article-title":"Phase 1 clinical study of pasufloxacin mesilate","volume":"47","author":"Nakajima","year":"1999","journal-title":"Jpn J Chemotherapy"},{"key":"10.1007\/s10156-008-0656-6_bib0075","first-page":"276","article-title":"Pharmacokinetics of prulifloxacin. First communication: absorption, distribution and excretion in rats, dogs and monkeys after a single administration","volume":"47","author":"Okuyama","year":"1997","journal-title":"Arzneimittelforschung"},{"key":"10.1007\/s10156-008-0656-6_bib0080","doi-asserted-by":"crossref","first-page":"2106","DOI":"10.1128\/AAC.35.10.2106","article-title":"Enantioselective disposition of ofloxacin in humans. Antimicrob","volume":"35","author":"Okazaki","year":"1991","journal-title":"Agents Chemother"},{"year":"2005","series-title":"Performance standards for antimicrobial susceptibility testing: 15th informational supplement. M100-S15","key":"10.1007\/s10156-008-0656-6_bib0085"},{"key":"10.1007\/s10156-008-0656-6_bib0090","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1086\/420816","article-title":"Antibiotic therapy for Klebsiella pneumoniae bacteremia: implications of production of extended-spectrum beta-lactamases","volume":"39","author":"Paterson","year":"2004","journal-title":"Clin Infect Dis"},{"key":"10.1007\/s10156-008-0656-6_bib0095","doi-asserted-by":"crossref","first-page":"2464","DOI":"10.1128\/AAC.48.7.2464-2470.2004","article-title":"Optimizing pharmacodynamic target attainment using the MYSTIC antibiogram: data collected in North America in 2002","volume":"48","author":"Kuti","year":"2004","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1007\/s10156-008-0656-6_bib0100","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1086\/321854","article-title":"Does the dose matter?","volume":"33","author":"Craig","year":"2001","journal-title":"Clin Infect Dis"},{"key":"10.1007\/s10156-008-0656-6_bib0105","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1128\/AAC.37.5.1073","article-title":"Pharmacodynamics of intravenous ciprofloxacin in seriously ill patients. Antimicrob","volume":"37","author":"Forrest","year":"1993","journal-title":"Agents Chemother"},{"key":"10.1007\/s10156-008-0656-6_bib0110","doi-asserted-by":"crossref","first-page":"1800","DOI":"10.1016\/j.clinthera.2004.11.009","article-title":"Pharmacodynamic modeling of carbapenems and fluoroquinolones against bacteria that produce extended-spectrum beta-lactamases","volume":"26","author":"Moczygemba","year":"2004","journal-title":"Clin Ther"}],"container-title":["Journal of Infection and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1341321X09707135?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1341321X09707135?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.springerlink.com\/index\/pdf\/10.1007\/s10156-008-0656-6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T18:46:37Z","timestamp":1761158797000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1341321X09707135"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009]]}},"alternative-id":["S1341321X09707135"],"URL":"https:\/\/doi.org\/10.1007\/s10156-008-0656-6","relation":{},"ISSN":["1341-321X"],"issn-type":[{"type":"print","value":"1341-321X"}],"subject":[],"published":{"date-parts":[[2009]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Monte Carlo simulation for evaluation of the efficacy of carbapenems and new quinolones against ESBL-producing Escherichia coli","name":"articletitle","label":"Article Title"},{"value":"Journal of Infection and Chemotherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1007\/s10156-008-0656-6","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 Japanese Society of Chemotherapy and the Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}