{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T22:15:25Z","timestamp":1777500925867,"version":"3.51.4"},"reference-count":19,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jiac-j.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Infection and Chemotherapy"],"published-print":{"date-parts":[[2013]]},"DOI":"10.1007\/s10156-013-0627-4","type":"journal-article","created":{"date-parts":[[2013,6,8]],"date-time":"2013-06-08T07:42:12Z","timestamp":1370677332000},"page":"1080-1086","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Intravenous itraconazole against experimental neutropenic Candida parapsilosis infection: efficacy after suppression of bacterial translocation"],"prefix":"10.1016","volume":"19","author":[{"given":"Dionyssia-Pinelopi","family":"Carrer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dionyssia-Irini","family":"Droggiti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Tsaganos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aikaterini","family":"Pistiki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Samonis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evangelos J.","family":"Giamarellos-Bourboulis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1007\/s10156-013-0627-4_bib0005","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/S1473-3099(03)00801-6","article-title":"Epidemiology of Candida species infections in critically ill non-immunosuppressed patients","volume":"3","author":"Eggimann","year":"2003","journal-title":"Lancet Infect Dis"},{"key":"10.1007\/s10156-013-0627-4_bib0010","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1111\/j.1469-0691.2005.01310.x","article-title":"Epidemiology of candidemia and antifungal susceptibility patterns in an Italian tertiary-care hospital","volume":"12","author":"Bedini","year":"2006","journal-title":"Clin Microbiol Infect"},{"key":"10.1007\/s10156-013-0627-4_bib0015","first-page":"4158","article-title":"Epidemiology and antifungal susceptibility of bloodstream fungal isolates in pediatric patients: a Spanish multicenter prospective survey","volume":"49","author":"Pem\u00e1n","year":"2011","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1007\/s10156-013-0627-4_bib0020","doi-asserted-by":"crossref","first-page":"839","DOI":"10.3109\/13693780903580121","article-title":"Five-year evaluation of bloodstream yeast infections in a tertiary hospital: the predominance of non-C. albicans Candida species","volume":"48","author":"Pereira","year":"2010","journal-title":"Med Mycol"},{"key":"10.1007\/s10156-013-0627-4_bib0025","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1080\/00365540701765657","article-title":"Candida albicans versus non-albicans bloodstream infection in patients in a tertiary hospital: an analysis of microbiological data","volume":"40","author":"Samonis","year":"2008","journal-title":"Scand J Infect Dis"},{"key":"10.1007\/s10156-013-0627-4_bib0030","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1093\/jac\/dkm145","article-title":"Epidemiology and antifungal susceptibilities of Candida spp. to six antifungal agents: results from a surveillance study of fungaemia in Germany from July 2004 to August 2005","volume":"60","author":"von Zepelin","year":"2007","journal-title":"J Antimicrob Chemother"},{"key":"10.1007\/s10156-013-0627-4_bib0035","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1007\/s10096-011-1242-x","article-title":"Characterization of Candida parapsilosis complex strains isolated from invasive fungal infections","volume":"30","author":"Borghi","year":"2011","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1007\/s10156-013-0627-4_bib0040","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1099\/jmm.0.037812-0","article-title":"Prevalence, distribution and antifungal susceptibility profiles of Candida parapsilosis, Candida orthopsilosis and Candida metapsilosis bloodstream isolates","volume":"61","author":"Bonfierri","year":"2012","journal-title":"J Med Microbiol"},{"key":"10.1007\/s10156-013-0627-4_bib0045","doi-asserted-by":"crossref","first-page":"5590","DOI":"10.1128\/AAC.00466-11","article-title":"Prospective multicenter study of the epidemiology, molecular identification, and antifungal susceptibility of Candida paraspilosis, Candida orthopsilosis and Candida metapsilosis isolated from patients with candidemia","volume":"55","author":"Cant\u00f3n","year":"2011","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1007\/s10156-013-0627-4_bib0050","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.ijantimicag.2006.09.009","article-title":"Colistin offers prolonged survival in experimental infection by multidrug-resistant Acinetobacter baumannii: the significance of co-administration of rifampicin","volume":"29","author":"Pantopoulou","year":"2007","journal-title":"Int J Antimicrob Agents"},{"key":"10.1007\/s10156-013-0627-4_bib0055","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1128\/AAC.01145-09","article-title":"Pharmacokinetics of itraconazole in diabetic rats","volume":"54","author":"Lee","year":"2010","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1007\/s10156-013-0627-4_bib0060","doi-asserted-by":"crossref","first-page":"1756","DOI":"10.1128\/AAC.48.5.1756-1762.2004","article-title":"Dose-dependent pharmacokinetics of itraconazole after intravenous or oral administration to rats: intestinal first-pass effect","volume":"48","author":"Shin","year":"2004","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1007\/s10156-013-0627-4_bib0065","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/S0378-5173(02)00272-7","article-title":"Hepatobiliary excretion of fluconazole and its interaction with cyclosporine A in rat blood and bile using microdialysis","volume":"241","author":"Lee","year":"2002","journal-title":"Int J Pharm"},{"key":"10.1007\/s10156-013-0627-4_bib0070","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1097\/00003246-199701000-00020","article-title":"A comparison of bactericidal\/permeability-increasing protein variant versus recombinant endotoxin-neutralizing protein for the treatment of Escherichia coli sepsis in rats","volume":"25","author":"Stack","year":"1997","journal-title":"Crit Care Med"},{"key":"10.1007\/s10156-013-0627-4_bib0075","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1111\/j.1440-1746.2007.04933.x","article-title":"Bacterial translocation: overview of mechanisms and clinical impact","volume":"22","author":"Balzan","year":"2007","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1007\/s10156-013-0627-4_bib0080","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1093\/jac\/dkq475","article-title":"Correlation of in vitro activity and in vivo efficacy of itraconazole intravenous and oral solubilized formulations by testing Candida strains with various itraconazole susceptibilities in a murine infection model","volume":"66","author":"Uchida","year":"2011","journal-title":"J Antimicrob Chemother"},{"key":"10.1007\/s10156-013-0627-4_bib0085","doi-asserted-by":"crossref","first-page":"2009","DOI":"10.1128\/AAC.00163-06","article-title":"In vitro activities of posaconazole, fluconazole, intraconazole, voriconazole, and amphotericin B against a large collection of clinically important molds and yeasts","volume":"50","author":"Sabatelli","year":"2006","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1007\/s10156-013-0627-4_bib0090","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1159\/000337088","article-title":"Comparisons of the kidney fungal burden in experimental disseminated candidiasis by species of the Candida parapsilosis complex treated with fluconazole, amphotericin B and caspofungin in a temporarily neutropenic murine model","volume":"58","author":"Szil\u00e1gyi","year":"2012","journal-title":"Chemotherapy"},{"key":"10.1007\/s10156-013-0627-4_bib0095","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1007\/s10156-012-0371-1","article-title":"Clinical efficacy and safety of intravenous itraconazole in the management of invasive candidiasis in patients of surgery and critical care","volume":"18","author":"Takesue","year":"2012","journal-title":"J Infect Chemother"}],"container-title":["Journal of Infection and Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1341321X13700102?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1341321X13700102?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10156-013-0627-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T18:49:34Z","timestamp":1761158974000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1341321X13700102"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":19,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013]]}},"alternative-id":["S1341321X13700102"],"URL":"https:\/\/doi.org\/10.1007\/s10156-013-0627-4","relation":{},"ISSN":["1341-321X"],"issn-type":[{"value":"1341-321X","type":"print"}],"subject":[],"published":{"date-parts":[[2013]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Intravenous itraconazole against experimental neutropenic Candida parapsilosis infection: efficacy after suppression of bacterial translocation","name":"articletitle","label":"Article Title"},{"value":"Journal of Infection and Chemotherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1007\/s10156-013-0627-4","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Japanese Society of Chemotherapy and the Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}