{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T22:27:43Z","timestamp":1791930463489,"version":"4.3.4"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2014,12,13]],"date-time":"2014-12-13T00:00:00Z","timestamp":1418428800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Exp Nephrol"],"published-print":{"date-parts":[[2015,10]]},"DOI":"10.1007\/s10157-014-1067-x","type":"journal-article","created":{"date-parts":[[2014,12,12]],"date-time":"2014-12-12T13:49:57Z","timestamp":1418392197000},"page":"804-814","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Clinical significance of serum and urinary soluble urokinase receptor (suPAR) in primary nephrotic syndrome and MPO-ANCA-associated glomerulonephritis in Japanese"],"prefix":"10.1007","volume":"19","author":[{"given":"Keiji","family":"Fujimoto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junko","family":"Imura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirokatsu","family":"Atsumi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuki","family":"Matsui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroki","family":"Adachi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Okuyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideki","family":"Yamaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hitoshi","family":"Yokoyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2014,12,13]]},"reference":[{"key":"1067_CR1","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1038\/nm.2411","volume":"17","author":"C Wei","year":"2011","unstructured":"Wei C, El Hindi S, Li J, Fornoni A, Goes N, Sageshima J, et al. Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis. Nat Med. 2011;17:952\u201360.","journal-title":"Nat Med"},{"key":"1067_CR2","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1038\/nm1696","volume":"14","author":"C Wei","year":"2008","unstructured":"Wei C, Moller CC, Altintas MM, Li J, Schwarz K, Zacchigna S, et al. Modification of kidney barrier function by the urokinase receptor. Nat Med. 2008;14:55\u201363.","journal-title":"Nat Med"},{"key":"1067_CR3","doi-asserted-by":"crossref","first-page":"2051","DOI":"10.1681\/ASN.2012030302","volume":"23","author":"C Wei","year":"2012","unstructured":"Wei C, Trachtman H, Li J, Dong C, Friedman AL, Gassman JJ, et al. Circulating suPAR in two cohorts of primary FSGS. J Am Soc Nephrol. 2012;23:2051\u20139.","journal-title":"J Am Soc Nephrol"},{"key":"1067_CR4","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1038\/ki.2013.55","volume":"84","author":"J Huang","year":"2013","unstructured":"Huang J, Liu G, Zhang YM, Cui Z, Wang F, Liu XJ, et al. Plasma soluble urokinase receptor levels are increased but do not distinguish primary from secondary focal segmental glomerulosclerosis. Kidney Int. 2013;84:366\u201372.","journal-title":"Kidney Int"},{"key":"1067_CR5","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1186\/1741-7015-12-81","volume":"12","author":"J Huang","year":"2014","unstructured":"Huang J, Liu G, Zhang YM, Cui Z, Wang F, Liu XJ, et al. Urinary soluble urokinase receptor levels are elevated and pathogenic in patients with primary focal segmental glomerulosclerosis. BMC Med. 2014;12:81. doi: 10.1186\/1741-7015-12-81 .","journal-title":"BMC Med"},{"issue":"3","key":"1067_CR6","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1038\/ki.2013.546","volume":"85","author":"A Sinha","year":"2014","unstructured":"Sinha A, Bajpai J, Saini S, Bhatia D, Gupta A, Puraswani M, et al. Serum-soluble urokinase receptor levels do not distinguish focal segmental glomerulosclerosis from other causes of nephrotic syndrome in children. Kidney Int. 2014;85(3):649\u201358.","journal-title":"Kidney Int"},{"key":"1067_CR7","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1038\/ki.2013.505","volume":"85","author":"B Meijers","year":"2014","unstructured":"Meijers B, Maas RJH, Sprangers B, Claes K, Poesen R, Bammens B, et al. The soluble urokinase receptor is not a clinical marker for focal segmental glomerulosclerosis. Kidney Int. 2014;85:636\u201340.","journal-title":"Kidney Int"},{"key":"1067_CR8","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1038\/ki.2013.544","volume":"85","author":"T Wada","year":"2014","unstructured":"Wada T, Nangaku M, Maruyama S, Imai E, Shoji K, Kato S, et al. A multicenter cross-sectional study of circulating soluble urokinase receptor in Japanese patients with glomerular disease. Kidney Int. 2014;85:641\u20138.","journal-title":"Kidney Int"},{"key":"1067_CR9","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1053\/j.ajkd.2008.12.034","volume":"53","author":"S Matsuo","year":"2009","unstructured":"Matsuo S, Imai E, Horio M, Yasuda Y, Tomita K, Nitta K, et al. Revised equations for estimated GFR from serum creatinine in Japan. Am J Kidney Dis. 2009;53:982\u201392.","journal-title":"Am J Kidney Dis"},{"key":"1067_CR10","first-page":"78","volume":"53","author":"The Japanese Society of Nephrology","year":"2011","unstructured":"The Japanese Society of Nephrology. Guidelines for the treatment of nephrotic syndrome. Nihon Jinzo Gakkai Shi. 2011;53:78\u2013122.","journal-title":"Nihon Jinzo Gakkai Shi"},{"key":"1067_CR11","first-page":"509","volume":"53","author":"The Japanese Society of Nephrology","year":"2011","unstructured":"The Japanese Society of Nephrology. Guidelines for the treatment of rapidly progressive glomerulonephritis. Nihon Jinzo Gakkai Shi. 2011;53:509\u201355.","journal-title":"Nihon Jinzo Gakkai Shi"},{"key":"1067_CR12","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1038\/ki.2012.32","volume":"81","author":"RJ Maas","year":"2012","unstructured":"Maas RJ, Wetzels JF, Deegens JK. Serum-soluble urokinase receptor concentration in primary FSGS. Kidney Int. 2012;81:1043\u20134.","journal-title":"Kidney Int"},{"key":"1067_CR13","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1007\/s00467-013-2452-5","volume":"28","author":"RJ Maas","year":"2013","unstructured":"Maas RJ, Deegens JK, Wetzels JF. Serum suPAR in patients with FSGS: trash or treasure? Prediatr Nephrol. 2013;28:1041\u20138.","journal-title":"Prediatr Nephrol"},{"key":"1067_CR14","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1007\/s00109-012-0960-6","volume":"90","author":"B Zang","year":"2012","unstructured":"Zang B, Shi W, Ma J, Sloan A, Faul C, Wei C, et al. The calcineurin-NFAT pathway allows for urokinase receptor-mediated \u03b23 integrin signaling to cause podocyte injury. J. Mol. Med. (Berl.). 2012;90:1407\u201320.","journal-title":"J. Mol. Med. (Berl.)"},{"key":"1067_CR15","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.2215\/CJN.07680712","volume":"8","author":"ME Bock","year":"2013","unstructured":"Bock ME, Price H, Gallon L, Langman CB. Serum soluble urokinase-type plasminogen activator receptor levels and idiopathic FSGS in children: A single-center reports. Clin Am Soc Nephrol. 2013;8:1304\u201311.","journal-title":"Clin Am Soc Nephrol"},{"key":"1067_CR16","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.1007\/s00134-012-2613-1","volume":"38","author":"Y Backes","year":"2012","unstructured":"Backes Y, van der Sluijs KF, Mackie DP, Tacke F, Koch A, Tenhunen JJ, et al. Usefulness of suPAR as a biological marker in patients with systemic inflammation or infection: a systematic review. Intensive Care Med. 2012;38:1418\u201328.","journal-title":"Intensive Care Med"},{"key":"1067_CR17","doi-asserted-by":"crossref","first-page":"R63","DOI":"10.1186\/cc10037","volume":"15","author":"A Koch","year":"2011","unstructured":"Koch A, Voigt S, Kruschinski C, Sanson E, Duckers H, Horn A, et al. Circulating soluble urokinase plasminogen activator receptor is stably elevated during the first week of treatment in the intensive care unit and predicts mortality in critically ill patients. Crit Care. 2011;15:R63.","journal-title":"Crit Care"},{"key":"1067_CR18","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1016\/j.clinbiochem.2011.07.006","volume":"44","author":"G Yilmaz","year":"2011","unstructured":"Yilmaz G, Koksal I, Karahan SC, Mentese A. The diagnostic and prognostic significance of soluble urokinase plasminogen activator receptor in systematic inflammatory response syndrome. Clin Biochem. 2011;44:1227\u201330.","journal-title":"Clin Biochem"},{"key":"1067_CR19","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1093\/ndt\/10.7.1155","volume":"10","author":"A Baraldi","year":"1995","unstructured":"Baraldi A, Zambruno G, Furci L, Ballestri M, Tombesi A, Ottani D, et al. \u03b21 and \u03b23 integrin upregulation in rapidly progressive glomerulonephritis. Nephrol Dial Transplant. 1995;10:1155\u201361.","journal-title":"Nephrol Dial Transplant"}],"container-title":["Clinical and Experimental Nephrology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10157-014-1067-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10157-014-1067-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10157-014-1067-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,18]],"date-time":"2019-08-18T11:32:19Z","timestamp":1566127939000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10157-014-1067-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,12,13]]},"references-count":19,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2015,10]]}},"alternative-id":["1067"],"URL":"https:\/\/doi.org\/10.1007\/s10157-014-1067-x","relation":{},"ISSN":["1342-1751","1437-7799"],"issn-type":[{"value":"1342-1751","type":"print"},{"value":"1437-7799","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,12,13]]}}}