{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T03:17:25Z","timestamp":1740107845263,"version":"3.37.3"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2017,10,27]],"date-time":"2017-10-27T00:00:00Z","timestamp":1509062400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Exp Nephrol"],"published-print":{"date-parts":[[2018,6]]},"DOI":"10.1007\/s10157-017-1488-4","type":"journal-article","created":{"date-parts":[[2017,10,27]],"date-time":"2017-10-27T01:08:44Z","timestamp":1509066524000},"page":"591-596","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Rationale and study design of a clinical trial to assess the effects of LDL apheresis on proteinuria in diabetic patients with severe proteinuria and dyslipidemia"],"prefix":"10.1007","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0123-3645","authenticated-orcid":false,"given":"Takashi","family":"Wada","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eri","family":"Muso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shoichi","family":"Maruyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akinori","family":"Hara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kengo","family":"Furuichi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenichi","family":"Yoshimura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariko","family":"Miyazaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eiichi","family":"Sato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masanori","family":"Abe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yugo","family":"Shibagaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ichiei","family":"Narita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hitoshi","family":"Yokoyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noriko","family":"Mori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukio","family":"Yuzawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Matsubara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatsuo","family":"Tsukamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Wada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takafumi","family":"Ito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kosuke","family":"Masutani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuhiko","family":"Tsuruya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shoichi","family":"Fujimoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akihiro","family":"Tsuda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hitoshi","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenji","family":"Kasuno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshio","family":"Terada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Nakata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noriaki","family":"Iino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuzo","family":"Kobayashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,10,27]]},"reference":[{"key":"1488_CR1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000187881","volume":"67","author":"C Guijarro","year":"1994","unstructured":"Guijarro C, Kean WF. Lipid-induced glomerular injury. Nephron. 1994;67:1\u20136.","journal-title":"Nephron"},{"key":"1488_CR2","first-page":"s41","volume":"39","author":"WF Kean","year":"1991","unstructured":"Kean WF, Mulcahy WS, Kasiske BL, Kim Y, O\u2019Donnell MP. Hyper-lipidemia and progressive renal disease. Kidney Int. 1991;39:s41\u20138.","journal-title":"Kidney Int"},{"key":"1488_CR3","first-page":"91","volume":"37","author":"S Kondo","year":"1995","unstructured":"Kondo S, Yoshizawa N, Wakabayashi K. Natural history of renal lesions in spontaneously hypercholesterolemic (SHC) male rats. Jpn J Nephrol. 1995;37:91\u20139.","journal-title":"Jpn J Nephrol"},{"key":"1488_CR4","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1007\/s10157-014-0996-8","volume":"19","author":"E Muso","year":"2015","unstructured":"Muso E, Mune M, Hirano T, Hattori M, Kimura K, Watanabe T, Yokoyama H, Sato H, Uchida S, Wada T, Shoji T, Yuzawa Y, Takemura T, Sugiyama S, Nishizawa Y, Ogahara S, Yorioka N, Sakai S, Ogura Y, Yukawa S, Iino Y, Imai E, Matsuo S, Saito T. Immediate therapeutic efficacy of low-density lipoprotein apheresis for drug-resistant nephrotic syndrome: evidence from the short-term results from the POLARIS Study. Clin Exp Nephrol. 2015;19:379\u201386.","journal-title":"Clin Exp Nephrol"},{"key":"1488_CR5","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1159\/000437338","volume":"5","author":"E Muso","year":"2015","unstructured":"Muso E, Mune M, Hirano T, Hattori M, Kimura K, Watanabe T, Yokoyama H, Sato H, Uchida S, Wada T, Shoji T, Takemura T, Yuzawa Y, Ogahara S, Sugiyama S, Iino Y, Sakai S, Ogura Y, Yukawa S, Nishizawa Y, Yorioka N, Imai E, Matsuo S, Saito T. A prospective observational survey on the long-term effect of LDL apheresis on drug-resistant nephrotic syndrome. Nephron Extra. 2015;5:58\u201366.","journal-title":"Nephron Extra"},{"key":"1488_CR6","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1159\/000045113","volume":"79","author":"S Kobayashi","year":"1998","unstructured":"Kobayashi S. LDL-apheresis for diabetic nephropathy: a possible new tool. Nephron. 1998;79:505\u20136.","journal-title":"Nephron"},{"key":"1488_CR7","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1053\/j.ajkd.2004.09.013","volume":"45","author":"T Nakamura","year":"2005","unstructured":"Nakamura T, Kawagoe Y, Ogawa H, et al. Effect of low-density lipoprotein apheresis on urinary protein and podocyte excretion in patients with nephrotic syndrome due to diabetic nephropathy. Am J Kid Dis. 2005;45:48\u201353.","journal-title":"Am J Kid Dis."},{"key":"1488_CR8","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.diabres.2014.08.012","volume":"106","author":"E Sato","year":"2014","unstructured":"Sato E, Amaha M, Nomura M, Matsumura D, Ueda Y, Nakamura T. LDL-apheresis contributes to survival extension and renal function maintenance of severe diabetic nephropathy patients: a retrospective analysis. Diabetes Res Clin Pract. 2014;106:241\u20136.","journal-title":"Diabetes Res Clin Pract"},{"key":"1488_CR9","doi-asserted-by":"crossref","first-page":"2978","DOI":"10.1007\/s00125-011-2325-z","volume":"54","author":"E Imai","year":"2011","unstructured":"Imai E, Chan JC, Ito S, Yamasaki T, Kobayashi F, Haneda M, Makino H, ORIENT\u00a0study investigators. Effects of olmesartan on renal and cardiovascular outcomes in type 2 diabetes with overt nephropathy: a multicentre, randomised, placebo-controlled study. Diabetologia. 2011;54:2978\u201386.","journal-title":"Diabetologia"},{"key":"1488_CR10","doi-asserted-by":"crossref","first-page":"2309","DOI":"10.1111\/j.1523-1755.2004.00653.x","volume":"65","author":"D Zeeuw de","year":"2004","unstructured":"de Zeeuw D, Remuzzi G, Parving HH, Keane WF, Zhang Z, Shahinfar S, Snapinn S, Cooper ME, Mitch WE, Brenner BM. Proteinuria, a target for renoprotection in patients with type 2 diabetic nephropathy: lessons from RENAAL. Kidney Int. 2004;65:2309\u201320.","journal-title":"Kidney Int"},{"key":"1488_CR11","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1007\/s10157-013-0879-4","volume":"18","author":"T Wada","year":"2014","unstructured":"Wada T, Haneda M, Furuichi K, Babazono T, Yokoyama H, Iseki K, Araki S, Ninomiya T, Hara S, Suzuki Y, Iwano M, Kusano E, Moriya T, Satoh H, Nakamura H, Shimizu M, Toyama T, Hara A, Makino H, Research Group of Diabetic Nephropathy, Ministry of Health, Labour, and Welfare of Japan. Clinical impact of albuminuria and glomerular filtration rate on renal and cardiovascular events, and all-cause mortality in Japanese patients with type 2 diabetes. Clin Exp Nephrol. 2014;18:613\u201320.","journal-title":"Clin Exp Nephrol"},{"key":"1488_CR12","doi-asserted-by":"crossref","first-page":"3655","DOI":"10.2337\/dc13-0298","volume":"36","author":"M Shimizu","year":"2013","unstructured":"Shimizu M, Furuichi K, Toyama T, Kitajima S, Hara A, Kitagawa K, Iwata Y, Sakai N, Takamura T, Yoshimura M, Yokoyama H, Kaneko S, Wada T, Kanazawa Study Group for Renal Diseases and Hypertension. Long-term outcomes of Japanese type 2 diabetic patients with biopsy-proven diabetic nephropathy. Diabetes Care. 2013;36:3655\u201362.","journal-title":"Diabetes Care"},{"key":"1488_CR13","doi-asserted-by":"crossref","first-page":"e71810","DOI":"10.1371\/journal.pone.0071810","volume":"8","author":"T Toyama","year":"2013","unstructured":"Toyama T, Furuichi K, Ninomiya T, Shimizu M, Hara A, Iwata Y, Kaneko S, Wada T. The impacts of albuminuria and low eGFR on the risk of cardiovascular death, all-cause mortality, and renal events in diabetic patients: meta-analysis. PLoS One. 2013;8:e71810.","journal-title":"PLoS One"},{"key":"1488_CR14","doi-asserted-by":"crossref","first-page":"S206","DOI":"10.1046\/j.1523-1755.1999.07153.x","volume":"71","author":"T Nakao","year":"1999","unstructured":"Nakao T, Yoshino M, Matsumoto H, Okada T, Han M, Hidaka H, Shino T, Yamada C, Nagaoka Y, Miyahara T. Low-density lipoprotein apheresis retards the progression of hyperlipidemic overt diabetic nephropathy. Kidney Int Suppl. 1999;71:S206\u20139.","journal-title":"Kidney Int Suppl"},{"key":"1488_CR15","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/s10157-013-0898-1","volume":"18","author":"T Toyama","year":"2014","unstructured":"Toyama T, Shimizu M, Furuichi K, Kaneko S, Wada T. Treatment and impact of\u00a0dyslipidemia\u00a0in\u00a0diabetic nephropathy. Clin Exp Nephrol. 2014;18:201\u20135.","journal-title":"Clin Exp Nephrol"}],"container-title":["Clinical and Experimental Nephrology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10157-017-1488-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10157-017-1488-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10157-017-1488-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,5,16]],"date-time":"2018-05-16T14:01:19Z","timestamp":1526479279000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10157-017-1488-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10,27]]},"references-count":15,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,6]]}},"alternative-id":["1488"],"URL":"https:\/\/doi.org\/10.1007\/s10157-017-1488-4","relation":{},"ISSN":["1342-1751","1437-7799"],"issn-type":[{"type":"print","value":"1342-1751"},{"type":"electronic","value":"1437-7799"}],"subject":[],"published":{"date-parts":[[2017,10,27]]}}}