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He has also received research funding from Kyowa Kirin and subsidies or donations from Chugai Pharmaceutical, Ono Pharmaceutical, Kyowa Kirin, and Bayer Pharmaceuticals. Dr. Yamagata has received lecture fees from Kyowa Kirin, Tanabe Mitsubishi, Mochida, Astellas, AstraZeneca, and Otsuka. He has also received research funding from Kyowa Kirin, Tanabe Mitsubishi, and Kaneka as well as subsidies or donations from Kyowa Kirin, Tanabe Mitsubishi, Astellas, and Chugai. The remaining authors have no conflicts of interest to declare.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The study protocol was approved by the Tsukuba Institutional Review Board (IRB) (H27-199), the review board of the Japanese Society of Nephrology (no. 29), and the IRBs of each participating facility. Informed consent was obtained from all individual participants included in the study. 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