{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T10:11:56Z","timestamp":1774260716691,"version":"3.50.1"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T00:00:00Z","timestamp":1770768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T00:00:00Z","timestamp":1770768000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Exp Nephrol"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1007\/s10157-026-02826-9","type":"journal-article","created":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T07:16:12Z","timestamp":1770794172000},"page":"604-614","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Associations between cardiovascular health metrics and mortality among adults with chronic kidney disease"],"prefix":"10.1007","volume":"30","author":[{"given":"Bin","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dongxi","family":"Hong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiaping","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guifen","family":"Guan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junnan","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yingyong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,2,11]]},"reference":[{"issue":"11","key":"2826_CR1","doi-asserted-by":"publisher","DOI":"10.7326\/AITC201506020","volume":"162","author":"P Drawz","year":"2015","unstructured":"Drawz P, Rahman M. Chronic kidney disease. Ann Intern Med. 2015;162(11):Itc1\u201316.","journal-title":"Ann Intern Med"},{"issue":"10225","key":"2826_CR2","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1016\/S0140-6736(20)30045-3","volume":"395","author":"B Bikbov","year":"2020","unstructured":"Bikbov B, Purcell CA, Levey AS, Smith M, Abdoli A, Abebe M, et al. Global, regional, and national burden of chronic kidney disease, 1990\u20132017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2020;395(10225):709\u201333.","journal-title":"Lancet"},{"issue":"11","key":"2826_CR3","doi-asserted-by":"publisher","first-page":"808","DOI":"10.1161\/CIRCULATIONAHA.121.053730","volume":"145","author":"NR Hasbani","year":"2022","unstructured":"Hasbani NR, Ligthart S, Brown MR, Heath AS, Bebo A, Ashley KE, et al. American Heart Association\u2019s Life\u2019s Simple 7: lifestyle recommendations, polygenic risk, and lifetime risk of coronary heart disease. Circulation. 2022;145(11):808\u201318.","journal-title":"Circulation"},{"issue":"20","key":"2826_CR4","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.124.036669","volume":"13","author":"J Ge","year":"2024","unstructured":"Ge J, Peng W, Lu J. Predictive value of Life\u2019s Crucial 9 for cardiovascular and all-cause mortality: a prospective cohort study from the NHANES 2007 to 2018. J Am Heart Assoc. 2024;13(20):e036669.","journal-title":"J Am Heart Assoc"},{"issue":"4","key":"2826_CR5","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.116.003192","volume":"5","author":"CM Rebholz","year":"2016","unstructured":"Rebholz CM, Anderson CA, Grams ME, Bazzano LA, Crews DC, Chang AR, et al. Relationship of the American Heart Association\u2019s impact goals (Life\u2019s Simple 7) with risk of chronic kidney disease: results from the Atherosclerosis Risk in Communities (ARIC) cohort study. J Am Heart Assoc. 2016;5(4):e003192.","journal-title":"J Am Heart Assoc"},{"issue":"7","key":"2826_CR6","doi-asserted-by":"publisher","first-page":"1159","DOI":"10.1681\/ASN.2012070642","volume":"24","author":"P Muntner","year":"2013","unstructured":"Muntner P, Judd SE, Gao L, Guti\u00e9rrez OM, Rizk DV, McClellan W, et al. Cardiovascular risk factors in CKD associate with both ESRD and mortality. J Am Soc Nephrol. 2013;24(7):1159\u201365.","journal-title":"J Am Soc Nephrol"},{"issue":"6","key":"2826_CR7","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1515\/jtim-2023-0119","volume":"12","author":"W Chen","year":"2024","unstructured":"Chen W, Tang Y, Si Y, Tu B, Xiao F, Bian X, et al. Association of life\u2019s essential 8 with prevalence and all-cause mortality of chronic kidney disease among US adults: results from the National Health and Nutrition Examination Survey (2015\u20132018). J Transl Int Med. 2024;12(6):581\u201391.","journal-title":"J Transl Int Med"},{"issue":"12","key":"2826_CR8","doi-asserted-by":"publisher","first-page":"905","DOI":"10.1161\/CIRCULATIONAHA.123.065472","volume":"149","author":"G Howard","year":"2024","unstructured":"Howard G, Cushman M, Blair J, Wilson NR, Yuan Y, Safford MM, et al. Comparative discrimination of Life\u2019s Simple 7 and Life\u2019s Essential 8 to stratify cardiovascular risk: is the added complexity worth it? Circulation. 2024;149(12):905\u201313.","journal-title":"Circulation"},{"key":"2826_CR9","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2023.107147","volume":"209","author":"W Gu","year":"2023","unstructured":"Gu W, Tian Z, Tian W, Song Y, Qi G, Qi J, et al. Association of rest-activity circadian rhythm with chronic respiratory diseases, a cross-section survey from NHANES 2011\u20132014. Respir Med. 2023;209:107147.","journal-title":"Respir Med"},{"issue":"4","key":"2826_CR10","first-page":"1","volume":"100","author":"K Disease","year":"2021","unstructured":"Disease K, Work IG KDIGO 2021. Clinical Practice Guideline for the Management of Glomerular Diseases. Kidney Int. 2021;100(4):1\u2013276.","journal-title":"Kidney Int."},{"issue":"4","key":"2826_CR11","doi-asserted-by":"publisher","first-page":"586","DOI":"10.1161\/CIRCULATIONAHA.109.192703","volume":"121","author":"DM Lloyd-Jones","year":"2010","unstructured":"Lloyd-Jones DM, Hong Y, Labarthe D, Mozaffarian D, Appel LJ, Van Horn L, et al. Defining and setting national goals for cardiovascular health promotion and disease reduction: the American Heart Association\u2019s strategic impact goal through 2020 and beyond. Circulation. 2010;121(4):586\u2013613.","journal-title":"Circulation"},{"issue":"5","key":"2826_CR12","doi-asserted-by":"publisher","first-page":"e18","DOI":"10.1161\/CIR.0000000000001078","volume":"146","author":"DM Lloyd-Jones","year":"2022","unstructured":"Lloyd-Jones DM, Allen NB, Anderson CAM, Black T, Brewer LC, Foraker RE, et al. Life\u2019s Essential 8: updating and enhancing the American Heart Association\u2019s construct of cardiovascular health: a presidential advisory from the American Heart Association. Circulation. 2022;146(5):e18\u201343.","journal-title":"Circulation"},{"issue":"9","key":"2826_CR13","doi-asserted-by":"publisher","first-page":"641","DOI":"10.1161\/CIRCULATIONAHA.123.066132","volume":"149","author":"AE Gaffey","year":"2024","unstructured":"Gaffey AE, Rollman BL, Burg MM. Strengthening the pillars of cardiovascular health: psychological health is a crucial component. Circulation. 2024;149(9):641\u20133.","journal-title":"Circulation"},{"issue":"6","key":"2826_CR14","doi-asserted-by":"publisher","first-page":"1453","DOI":"10.2337\/dc21-2371","volume":"45","author":"Z Qiu","year":"2022","unstructured":"Qiu Z, Chen X, Geng T, Wan Z, Lu Q, Li L, et al. Associations of serum carotenoids with risk of cardiovascular mortality among individuals with type 2 diabetes: results from NHANES. Diabetes Care. 2022;45(6):1453\u201361.","journal-title":"Diabetes Care"},{"issue":"4","key":"2826_CR15","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.122.027568","volume":"12","author":"X Zhu","year":"2023","unstructured":"Zhu X, Cheang I, Tang Y, Shi M, Zhu Q, Gao R, et al. Associations of serum carotenoids with risk of all-cause and cardiovascular mortality in hypertensive adults. J Am Heart Assoc. 2023;12(4):e027568.","journal-title":"J Am Heart Assoc"},{"issue":"11","key":"2826_CR16","doi-asserted-by":"publisher","first-page":"5126","DOI":"10.1111\/dom.15854","volume":"26","author":"G Ni","year":"2024","unstructured":"Ni G, Jia Q, Li Y, Cheang I, Zhu X, Zhang H, et al. Association of life\u2019s essential 8 with abdominal aortic calcification and mortality among middle-aged and older individuals. Diabetes Obes Metab. 2024;26(11):5126\u201337.","journal-title":"Diabetes Obes Metab"},{"issue":"1","key":"2826_CR17","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-023-02824-8","volume":"21","author":"J Sun","year":"2023","unstructured":"Sun J, Li Y, Zhao M, Yu X, Zhang C, Magnussen CG, et al. Association of the American Heart Association\u2019s new \u201cLife\u2019s Essential 8\u201d with all-cause and cardiovascular disease-specific mortality: prospective cohort study. BMC Med. 2023;21(1):116.","journal-title":"BMC Med"},{"issue":"8","key":"2826_CR18","doi-asserted-by":"publisher","first-page":"1837","DOI":"10.1016\/j.numecd.2024.03.024","volume":"34","author":"S Zhang","year":"2024","unstructured":"Zhang S, Xue Q, Li D, Xu Y, Zhang YB, Peng J, et al. Association of cardiovascular health metrics with all-cause and cardiovascular disease mortality in chronic kidney disease: a cohort study. Nutr Metab Cardiovasc Dis. 2024;34(8):1837\u201345.","journal-title":"Nutr Metab Cardiovasc Dis"},{"issue":"4","key":"2826_CR19","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpcardiol.2022.101540","volume":"48","author":"F Petermann-Rocha","year":"2023","unstructured":"Petermann-Rocha F, Deo S, Celis-Morales C, Ho FK, Bahuguna P, McAllister D, et al. An opportunity for prevention: associations between the life\u2019s essential 8 score and cardiovascular incidence using prospective data from UK Biobank. Curr Probl Cardiol. 2023;48(4):101540.","journal-title":"Curr Probl Cardiol"},{"issue":"11\u201312","key":"2826_CR20","doi-asserted-by":"publisher","first-page":"516","DOI":"10.1159\/000533257","volume":"54","author":"H Chen","year":"2023","unstructured":"Chen H, Tang H, Huang J, Luo N, Zhang X, Wang X. Life\u2019s essential 8 and mortality in US adults with chronic kidney disease. Am J Nephrol. 2023;54(11\u201312):516\u201327.","journal-title":"Am J Nephrol"},{"issue":"7","key":"2826_CR21","doi-asserted-by":"publisher","first-page":"824","DOI":"10.1093\/eurjpc\/zwad398","volume":"31","author":"Z Huo","year":"2024","unstructured":"Huo Z, Huang Z, Feng J, Li J, Chen S, Wang G, et al. Life\u2019s essential 8 and heart failure among patients with chronic kidney disease: the Kailuan Cohort Study. Eur J Prev Cardiol. 2024;31(7):824\u201331.","journal-title":"Eur J Prev Cardiol"},{"issue":"3","key":"2826_CR22","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1053\/j.ajkd.2013.02.369","volume":"62","author":"SC Palmer","year":"2013","unstructured":"Palmer SC, Vecchio M, Craig JC, Tonelli M, Johnson DW, Nicolucci A, et al. Association between depression and death in people with CKD: a meta-analysis of cohort studies. Am J Kidney Dis. 2013;62(3):493\u2013505.","journal-title":"Am J Kidney Dis"},{"key":"2826_CR23","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2020.112802","volume":"285","author":"M Shao","year":"2020","unstructured":"Shao M, Lin X, Jiang D, Tian H, Xu Y, Wang L, et al. Depression and cardiovascular disease: shared molecular mechanisms and clinical implications. Psychiatry Res. 2020;285:112802.","journal-title":"Psychiatry Res"},{"issue":"2","key":"2826_CR24","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1016\/j.ekir.2018.11.013","volume":"4","author":"S Shirazian","year":"2019","unstructured":"Shirazian S. Depression in CKD: understanding the mechanisms of disease. Kidney Int Rep. 2019;4(2):189\u201390.","journal-title":"Kidney Int Rep"},{"issue":"23","key":"2826_CR25","doi-asserted-by":"publisher","first-page":"2148","DOI":"10.1093\/eurheartj\/ehaf167","volume":"46","author":"K Marx-Sch\u00fctt","year":"2025","unstructured":"Marx-Sch\u00fctt K, Cherney DZI, Jankowski J, Matsushita K, Nardone M, Marx N. Cardiovascular disease in chronic kidney disease. Eur Heart J. 2025;46(23):2148\u201360.","journal-title":"Eur Heart J"},{"issue":"9","key":"2826_CR26","doi-asserted-by":"publisher","first-page":"1210","DOI":"10.5551\/jat.63891","volume":"30","author":"H Kitamura","year":"2023","unstructured":"Kitamura H, Tanaka S, Hiyamuta H, Shimamoto S, Tsuruya K, Nakano T, et al. Cardiovascular risk factor burden and treatment control in patients with chronic kidney disease: a cross-sectional study. J Atheroscler Thromb. 2023;30(9):1210\u201388.","journal-title":"J Atheroscler Thromb"},{"issue":"12","key":"2826_CR27","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2023-074025","volume":"13","author":"OA Adejumo","year":"2023","unstructured":"Adejumo OA, Edeki IR, Mamven M, Oguntola OS, Okoye OC, Akinbodewa AA, et al. Sleep quality and associated factors among patients with chronic kidney disease in Nigeria: a cross-sectional study. BMJ Open. 2023;13(12):e074025.","journal-title":"BMJ Open"},{"issue":"10","key":"2826_CR28","doi-asserted-by":"publisher","DOI":"10.1016\/j.xkme.2023.100712","volume":"5","author":"CK Cardol","year":"2023","unstructured":"Cardol CK, Meuleman Y, van Middendorp H, van der Boog PJM, Hilbrands LB, Navis G, et al. Psychological distress and self-management in CKD: a cross-sectional study. Kidney Med. 2023;5(10):100712.","journal-title":"Kidney Med"},{"key":"2826_CR29","doi-asserted-by":"publisher","DOI":"10.3389\/fneph.2025.1600296","volume":"5","author":"RA Nablawi","year":"2025","unstructured":"Nablawi RA, Alghamdi LS, Alshaikh AE, Alagha AM, Alharbi NT, Ali AH, et al. Quality of life and depression among chronic kidney disease patients: a tertiary care center cross-sectional study. Front Nephrol. 2025;5:1600296.","journal-title":"Front Nephrol"},{"key":"2826_CR30","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2022.880276","volume":"10","author":"Q Jin","year":"2022","unstructured":"Jin Q, Yang N, Dai J, Zhao Y, Zhang X, Yin J, et al. Association of sleep duration with all-cause and cardiovascular mortality: a prospective cohort study. Front Public Health. 2022;10:880276.","journal-title":"Front Public Health"},{"key":"2826_CR31","doi-asserted-by":"publisher","first-page":"1072238","DOI":"10.3389\/fpubh.2022.1072238","volume":"10","author":"S Xu","year":"2022","unstructured":"Xu S, Jin J, Dong Q, Gu C, Wu Y, Zhang H, et al. Association between sleep duration and quality with rapid kidney function decline and development of chronic kidney diseases in adults with normal kidney function: The China health and retirement longitudinal study. Front Public Heal. 2022;10:1072238.","journal-title":"Front Public Heal"},{"issue":"1","key":"2826_CR32","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-025-04116-9","volume":"23","author":"X Zhu","year":"2025","unstructured":"Zhu X, Cheang I, Fu Y, Chen S, Liang G, Yuan H, et al. Comparative Discrimination of Life\u2019s Simple 7, Life\u2019s Essential 8, and Life\u2019s Crucial 9: evaluating the impact of added complexity on mortality prediction. BMC Med. 2025;23(1):265.","journal-title":"BMC Med"}],"container-title":["Clinical and Experimental Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10157-026-02826-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10157-026-02826-9","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10157-026-02826-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T09:28:24Z","timestamp":1774258104000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10157-026-02826-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,11]]},"references-count":32,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["2826"],"URL":"https:\/\/doi.org\/10.1007\/s10157-026-02826-9","relation":{},"ISSN":["1342-1751","1437-7799"],"issn-type":[{"value":"1342-1751","type":"print"},{"value":"1437-7799","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,11]]},"assertion":[{"value":"20 October 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 January 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 February 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no competing interests to declare.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All participants provided written informed consent and study procedures were approved by the National Center for Health Statistics Research Ethics Review Board (Protocol Number: Protocol #2005\u201306 and Protocol #2011\u201317).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to publish"}},{"value":"Not applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable. This study was not a clinical trial.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Clinical trial registration"}}]}}