{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T10:17:22Z","timestamp":1787912242665,"version":"build-2784847793"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2020,8,17]],"date-time":"2020-08-17T00:00:00Z","timestamp":1597622400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,8,17]],"date-time":"2020-08-17T00:00:00Z","timestamp":1597622400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/100000055","name":"National Institute on Deafness and Other Communication Disorders","doi-asserted-by":"publisher","award":["R03DC11612-4"],"award-info":[{"award-number":["R03DC11612-4"]}],"id":[{"id":"10.13039\/100000055","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["JARO"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1007\/s10162-020-00744-5","type":"journal-article","created":{"date-parts":[[2020,8,17]],"date-time":"2020-08-17T14:12:09Z","timestamp":1597673529000},"page":"475-483","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Gap Detection Deficits in Chinchillas with Selective Carboplatin-Induced Inner Hair Cell Loss"],"prefix":"10.1007","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6782-8142","authenticated-orcid":false,"given":"Edward","family":"Lobarinas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Salvi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dalian","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,8,17]]},"reference":[{"key":"744_CR1","doi-asserted-by":"crossref","first-page":"1660","DOI":"10.1121\/1.385198","volume":"68","author":"JB Allen","year":"1980","unstructured":"Allen JB (1980) Cochlear micromechanics--a physical model of transduction. J Acoust Soc Am 68:1660\u20131670","journal-title":"J Acoust Soc Am"},{"key":"744_CR2","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1121\/1.381767","volume":"63","author":"EA Blakeslee","year":"1978","unstructured":"Blakeslee EA, Hynson K, Hamernik RP, Henderson D (1978) Asymptotic threshold shift in chinchillas exposed to impulse noise. J Acoust Soc Am 63:876\u2013882","journal-title":"J Acoust Soc Am"},{"key":"744_CR3","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/0378-5955(87)90129-8","volume":"30","author":"E Borg","year":"1987","unstructured":"Borg E (1987) Loss of hair cells and threshold sensitivity during prolonged noise exposure in normotensive albino rats. Hear Res 30:119\u2013126","journal-title":"Hear Res"},{"key":"744_CR4","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1038\/315662a0","volume":"315","author":"AR Cody","year":"1985","unstructured":"Cody AR, Russell IJ (1985) Outer hair cells in the mammalian cochlea and noise-induced hearing loss. Nature 315:662\u2013665","journal-title":"Nature"},{"key":"744_CR5","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1152\/jn.1978.41.2.365","volume":"41","author":"P Dallos","year":"1978","unstructured":"Dallos P, Harris D (1978) Properties of auditory nerve responses in absence of outer hair cells. J Neurophysiol 41:365\u2013383","journal-title":"J Neurophysiol"},{"key":"744_CR6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0378-5955(89)90173-1","volume":"41","author":"RI Davis","year":"1989","unstructured":"Davis RI, Ahroon WA, Hamernik RP (1989) The relation among hearing loss, sensory cell loss and tuning characteristics in the chinchilla. Hear Res 41:1\u201314","journal-title":"Hear Res"},{"key":"744_CR7","doi-asserted-by":"crossref","first-page":"69","DOI":"10.3766\/jaaa.16.2.2","volume":"16","author":"B Davis","year":"2005","unstructured":"Davis B, Qiu W, Hamernik RP (2005) Sensitivity of distortion product otoacoustic emissions in noise-exposed chinchillas. J Am Acad Audiol 16:69\u201378","journal-title":"J Am Acad Audiol"},{"key":"744_CR8","unstructured":"Ding D, Li M, Zheng X, Wang J, Salvi RJ (1999a) Cochleogram for assessing hair cells and efferent fibers in carboplatin-treated ear. Lin Chuang Er Bi Yan Hou Ke Za Zhi J Clin Otorhinolaryngol 13:510-512"},{"key":"744_CR9","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1111\/j.1749-6632.1999.tb08640.x","volume":"884","author":"DL Ding","year":"1999","unstructured":"Ding DL, Wang J, Salvi R, Henderson D, Hu BH, McFadden SL, Mueller M (1999b) Selective loss of inner hair cells and type-I ganglion neurons in carboplatin-treated chinchillas. Mechanisms of damage and protection. Ann N Y Acad Sci 884:152\u2013170","journal-title":"Ann N Y Acad Sci"},{"key":"744_CR10","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.heares.2009.06.003","volume":"255","author":"MM El-Badry","year":"2009","unstructured":"El-Badry MM, McFadden SL (2009) Evaluation of inner hair cell and nerve fiber loss as sufficient pathologies underlying auditory neuropathy. Hear Res 255:84\u201390","journal-title":"Hear Res"},{"key":"744_CR11","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1121\/1.384818","volume":"68","author":"D Giraudi","year":"1980","unstructured":"Giraudi D, Salvi R, Henderson D, Hamernik R (1980) Gap detection by the chinchilla. J Acoust Soc Am 68:802\u2013806","journal-title":"J Acoust Soc Am"},{"key":"744_CR12","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1121\/1.388444","volume":"72","author":"DM Giraudi-Perry","year":"1982","unstructured":"Giraudi-Perry DM, Salvi RJ, Henderson D (1982) Gap detection in hearing-impaired chinchillas. J Acoust Soc Am 72:1387\u20131393","journal-title":"J Acoust Soc Am"},{"key":"744_CR13","doi-asserted-by":"crossref","first-page":"2592","DOI":"10.1121\/1.399052","volume":"87","author":"DD Greenwood","year":"1990","unstructured":"Greenwood DD (1990) A cochlear frequency-position function for several species--29 years later. J Acoust Soc Am 87:2592\u20132605","journal-title":"J Acoust Soc Am"},{"key":"744_CR14","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/0378-5955(89)90065-8","volume":"38","author":"RP Hamernik","year":"1989","unstructured":"Hamernik RP, Patterson JH, Turrentine GA, Ahroon WA (1989) The quantitative relation between sensory cell loss and hearing thresholds. Hear Res 38:199\u2013211","journal-title":"Hear Res"},{"key":"744_CR15","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/0378-5955(91)90183-A","volume":"52","author":"RS Heffner","year":"1991","unstructured":"Heffner RS, Heffner HE (1991) Behavioral hearing range of the chinchilla. Hear Res 52:13\u201316","journal-title":"Hear Res"},{"key":"744_CR16","doi-asserted-by":"crossref","first-page":"301","DOI":"10.3109\/00206099709071981","volume":"36","author":"P Hofstetter","year":"1997","unstructured":"Hofstetter P, Ding D, Salvi R (1997a) Magnitude and pattern of inner and outer hair cell loss in chinchilla as a function of carboplatin dose. Audiology 36:301\u2013311","journal-title":"Audiology"},{"key":"744_CR17","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/S0378-5955(97)00123-8","volume":"112","author":"P Hofstetter","year":"1997","unstructured":"Hofstetter P, Ding D, Powers N, Salvi RJ (1997b) Quantitative relationship of carboplatin dose to magnitude of inner and outer hair cell loss and the reduction in distortion product otoacoustic emission amplitude in chinchillas. Hear Res 112:199\u2013215","journal-title":"Hear Res"},{"key":"744_CR18","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/0378-5955(86)90090-0","volume":"22","author":"BM Johnstone","year":"1986","unstructured":"Johnstone BM, Patuzzi R, Yates GK (1986) Basilar membrane measurements and the travelling wave. Hear Res 22:147\u2013153","journal-title":"Hear Res"},{"key":"744_CR19","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.heares.2013.03.012","volume":"302","author":"E Lobarinas","year":"2013","unstructured":"Lobarinas E, Salvi R, Ding D (2013) Insensitivity of the audiogram to carboplatin induced inner hair cell loss in chinchillas. Hear Res 302:113\u2013120","journal-title":"Hear Res"},{"key":"744_CR20","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1007\/s10162-015-0550-8","volume":"17","author":"E Lobarinas","year":"2016","unstructured":"Lobarinas E, Salvi R, Ding D (2016) Selective inner hair cell dysfunction in chinchillas impairs hearing-in-noise in the absence of outer hair cell loss. J Assoc Res Otolaryngol 17:89\u2013101","journal-title":"J Assoc Res Otolaryngol"},{"key":"744_CR21","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/S0378-5955(02)00697-4","volume":"174","author":"SL McFadden","year":"2002","unstructured":"McFadden SL, Ding D, Jiang H, Woo JM, Salvi RJ (2002) Chinchilla models of selective cochlear hair cell loss. Hear Res 174:230\u2013238","journal-title":"Hear Res"},{"key":"744_CR22","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1288\/00005537-197609000-00001","volume":"86","author":"TJ McGill","year":"1976","unstructured":"McGill TJ, Schuknecht HF (1976) Human cochlear changes in noise induced hearing loss. Laryngoscope 86:1293\u20131302","journal-title":"Laryngoscope"},{"key":"744_CR23","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1121\/1.1912166","volume":"48","author":"JD Miller","year":"1970","unstructured":"Miller JD (1970) Audibility curve of the chinchilla. J Acoust Soc Am 48:513\u2013523","journal-title":"J Acoust Soc Am"},{"key":"744_CR24","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1177\/019459989110400203","volume":"104","author":"LA Ohlms","year":"1991","unstructured":"Ohlms LA, Lonsbury-Martin BL, Martin GK (1991) Acoustic-distortion products: separation of sensory from neural dysfunction in sensorineural hearing loss in human beings and rabbits. Otolaryngol Head Neck Surg 104:159\u2013174","journal-title":"Otolaryngol Head Neck Surg"},{"key":"744_CR25","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/0378-5955(89)90117-2","volume":"42","author":"RB Patuzzi","year":"1989","unstructured":"Patuzzi RB, Yates GK, Johnstone BM (1989) Outer hair cell receptor current and sensorineural hearing loss. Hear Res 42:47\u201372","journal-title":"Hear Res"},{"key":"744_CR26","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1159\/000259185","volume":"1","author":"S Preyer","year":"1996","unstructured":"Preyer S, Gummer AW (1996) Nonlinearity of mechanoelectrical transduction of outer hair cells as the source of nonlinear basilar-membrane motion and loudness recruitment. Audiol Neuro-otol 1:3\u201311","journal-title":"Audiol Neuro-otol"},{"key":"744_CR27","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S0378-5955(99)00171-9","volume":"139","author":"C Qiu","year":"2000","unstructured":"Qiu C, Salvi R, Ding D, Burkard R (2000) Inner hair cell loss leads to enhanced response amplitudes in auditory cortex of unanesthetized chinchillas: evidence for increased system gain. Hear Res 139:153\u2013171","journal-title":"Hear Res"},{"key":"744_CR28","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1121\/1.392181","volume":"77","author":"RJ Salvi","year":"1985","unstructured":"Salvi RJ, Arehole S (1985) Gap detection in chinchillas with temporary high-frequency hearing loss. J Acoust Soc Am 77:1173\u20131177","journal-title":"J Acoust Soc Am"},{"key":"744_CR29","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1007\/BF00238704","volume":"32","author":"RJ Salvi","year":"1978","unstructured":"Salvi RJ, Hamernik RP, Henderson D (1978) Discharge patterns in the cochlear nucleus of the chinchilla following noise induced asymptotic threshold shift. Exp Brain Res 32:301\u2013320","journal-title":"Exp Brain Res"},{"key":"744_CR30","doi-asserted-by":"crossref","first-page":"383","DOI":"10.3109\/00206097509071752","volume":"14","author":"H Spoendlin","year":"1975","unstructured":"Spoendlin H (1975) Neuroanatomical basis of cochlear coding mechanisms. Audiology 14:383\u2013407","journal-title":"Audiology"},{"key":"744_CR31","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S0196-0709(79)80004-6","volume":"1","author":"WC Stebbins","year":"1979","unstructured":"Stebbins WC, Hawkins JE Jr, Johnson LG, Moody DB (1979) Hearing thresholds with outer and inner hair cell loss. Am J Otolaryngol 1:15\u201327","journal-title":"Am J Otolaryngol"},{"key":"744_CR32","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/0378-5955(96)00040-8","volume":"96","author":"P Trautwein","year":"1996","unstructured":"Trautwein P, Hofstetter P, Wang J, Salvi R, Nostrant A (1996) Selective inner hair cell loss does not alter distortion product otoacoustic emissions. Hear Res 96:71\u201382","journal-title":"Hear Res"},{"key":"744_CR33","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0378-5955(97)00020-8","volume":"107","author":"J Wang","year":"1997","unstructured":"Wang J, Powers NL, Hofstetter P, Trautwein P, Ding D, Salvi R (1997) Effects of selective inner hair cell loss on auditory nerve fiber threshold, tuning and spontaneous and driven discharge rate. Hear Res 107:67\u201382","journal-title":"Hear Res"}],"container-title":["Journal of the Association for Research in Otolaryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10162-020-00744-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10162-020-00744-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10162-020-00744-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,17]],"date-time":"2021-08-17T00:09:43Z","timestamp":1629158983000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10162-020-00744-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,17]]},"references-count":33,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["744"],"URL":"https:\/\/doi.org\/10.1007\/s10162-020-00744-5","relation":{},"ISSN":["1525-3961","1438-7573"],"issn-type":[{"value":"1525-3961","type":"print"},{"value":"1438-7573","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,17]]},"assertion":[{"value":"4 October 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 February 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 August 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}