{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T04:30:35Z","timestamp":1779165035710,"version":"3.51.4"},"reference-count":80,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2022,1,27]],"date-time":"2022-01-27T00:00:00Z","timestamp":1643241600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,1,27]],"date-time":"2022-01-27T00:00:00Z","timestamp":1643241600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["JARO"],"published-print":{"date-parts":[[2022,4]]},"DOI":"10.1007\/s10162-022-00835-5","type":"journal-article","created":{"date-parts":[[2022,1,27]],"date-time":"2022-01-27T16:27:47Z","timestamp":1643300867000},"page":"225-239","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Auditory Behavior in Adult-Blinded Mice"],"prefix":"10.1007","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2769-2604","authenticated-orcid":false,"given":"Ye-Hyun","family":"Kim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9963-9642","authenticated-orcid":false,"given":"Katrina M.","family":"Schrode","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Engel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergio","family":"Vicencio-Jimenez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriela","family":"Rodriguez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5554-983X","authenticated-orcid":false,"given":"Hey-Kyoung","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4184-7374","authenticated-orcid":false,"given":"Amanda M.","family":"Lauer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,1,27]]},"reference":[{"key":"835_CR1","doi-asserted-by":"crossref","unstructured":"Aedo C, Terreros G, Le\u00f3n A, Delano PH (2016) The corticofugal effects of auditory cortex microstimulation on auditory nerve and superior olivary complex responses are mediated via alpha-9 nicotinic receptor subunit. PloS One 11(5):e01555991","DOI":"10.1371\/journal.pone.0155991"},{"key":"835_CR2","doi-asserted-by":"crossref","unstructured":"Aizenberg M, Mwilambwe-Tshilobo L, Briguglio JJ, Natan RG, Geffen MN (2015) Bidirectional regulation of innate and learned behaviors that rely on frequency discrimination by cortical inhibitory neurons. Plos Biol 13(12):e1002308.","DOI":"10.1371\/journal.pbio.1002308"},{"key":"835_CR3","doi-asserted-by":"crossref","unstructured":"Asilador A, Llano DA (2021) Top-down inference in the auditory system: potential roles for corticofugal projections. Front Neural Circuits 14:615259.","DOI":"10.3389\/fncir.2020.615259"},{"key":"835_CR4","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1038\/nrn848","volume":"3","author":"D Bavelier","year":"2002","unstructured":"Bavelier D, Neville HJ (2002) Cross-modal plasticity: where and how? Nat Rev Neurosci 3:443\u2013452. https:\/\/doi.org\/10.1038\/nrn848","journal-title":"Nat Rev Neurosci"},{"key":"835_CR5","doi-asserted-by":"publisher","first-page":"1905","DOI":"10.1121\/1.5101911","volume":"145","author":"KM Bieszczad","year":"2019","unstructured":"Bieszczad KM (2019) Neural correlates of sound-learning experiences in the auditory system: translational candidates for hearing rehabilitation. J Acoust Soc Am 145:1905. https:\/\/doi.org\/10.1121\/1.5101911","journal-title":"J Acoust Soc Am"},{"key":"835_CR6","doi-asserted-by":"publisher","unstructured":"Blackwell JM, Lesicko AM, Rao W, De Biasi M, Geffen MN (2020) Auditory cortex shapes sound responses in the inferior colliculus. eLife 9:e51890. https:\/\/doi.org\/10.7554\/eLife.51890","DOI":"10.7554\/eLife.51890"},{"key":"835_CR7","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1093\/cercor\/13.8.815","volume":"13","author":"GP Bowen","year":"2003","unstructured":"Bowen GP, Lin D, Taylor MK, Ison JR (2003) Auditory cortex lesions in the rat impair both temporal acuity and noise increment thresholds, revealing a common neural substrate. Cereb Cortex 13:815\u2013822. https:\/\/doi.org\/10.1093\/cercor\/13.8.815","journal-title":"Cereb Cortex"},{"issue":"4","key":"835_CR8","doi-asserted-by":"publisher","first-page":"867","DOI":"10.1016\/j.neuron.2015.12.041","volume":"89","author":"AR Chambers","year":"2016","unstructured":"Chambers AR, Resnik J, Yuan Y, Whitton JP, Edge AS, Liberman MC, Polley DB (2016) Central gain restores auditory processing following near-complete cochlear denervation. Neuron 89(4):867\u2013879. https:\/\/doi.org\/10.1016\/j.neuron.2015.12.041","journal-title":"Neuron"},{"key":"835_CR9","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1007\/s10548-013-0323-9","volume":"27","author":"B Chandrasekaran","year":"2014","unstructured":"Chandrasekaran B, Skoe E, Kraus N (2014) An integrative model of subcortical auditory plasticity. Brain Topogr 27:539\u2013552. https:\/\/doi.org\/10.1007\/s10548-013-0323-9","journal-title":"Brain Topogr"},{"key":"835_CR10","doi-asserted-by":"publisher","first-page":"4412","DOI":"10.1210\/en.2012-1416","volume":"153","author":"K Charitidi","year":"2012","unstructured":"Charitidi K, Meltser I, Canlon B (2012) Estradiol treatment and hormonal fluctuations during the estrous cycle modulate the expression of estrogen receptors in the auditory system and the prepulse inhibition of acoustic startle response. Endocrinology 153:4412\u20134421. https:\/\/doi.org\/10.1210\/en.2012-1416","journal-title":"Endocrinology"},{"key":"835_CR11","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fncel.2017.00167","volume":"11","author":"A Clause","year":"2017","unstructured":"Clause A, Lauer AM, Kandler K (2017) Mice lacking the alpha9 subunit of the nicotinic acetylcholine receptor exhibit deficits in frequency difference limens and sound localization. Front Cell Neurosci 11:1\u201312. https:\/\/doi.org\/10.3389\/fncel.2017.00167","journal-title":"Front Cell Neurosci"},{"key":"835_CR12","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1016\/j.jneumeth.2011.05.027","volume":"200","author":"A Clause","year":"2011","unstructured":"Clause A, Nguyen T, Kandler K (2011) An acoustic startle-based method of assessing frequency discrimination in mice. J Neurosci Methods 200:63\u201367. https:\/\/doi.org\/10.1016\/j.jneumeth.2011.05.027","journal-title":"J Neurosci Methods"},{"issue":"3","key":"835_CR13","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1037\/h0077345","volume":"91","author":"M Davis","year":"1977","unstructured":"Davis M, Gendelman PM (1977) Plasticity of the acoustic startle response in the acutely decerebrate rat. J Comp Physiol Psychol 91(3):549\u2013563. https:\/\/doi.org\/10.1037\/h0077345","journal-title":"J Comp Physiol Psychol"},{"key":"835_CR14","doi-asserted-by":"publisher","unstructured":"Dent ML, Screven LA, Kobrina A (2018) Hearing in rodents. In Rodent bioacoustics ML, Dent RR, Fay AN, Popper (Eds.) Springer International Publishing, Cham. pp 71\u2013105. https:\/\/doi.org\/10.1007\/978-3-319-92495-3_4","DOI":"10.1007\/978-3-319-92495-3_4"},{"key":"835_CR15","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1007\/s00221-005-2329-3","volume":"165","author":"A Dufour","year":"2005","unstructured":"Dufour A, Despr\u00e9s O, Candas V (2005) Enhanced sensitivity to echo cues in blind subjects. Exp Brain Res 165:515\u2013519. https:\/\/doi.org\/10.1007\/s00221-005-2329-3","journal-title":"Exp Brain Res"},{"key":"835_CR16","doi-asserted-by":"publisher","unstructured":"Ewall G, Parkins S, Lin A, Jaoui Y, Lee H (2021) Cortical and subcortical circuits for cross-modal plasticity induced by loss of vision. Front. Neural Circuits 15:665009. https:\/\/doi.org\/10.3389\/fncir.2021.665009","DOI":"10.3389\/fncir.2021.665009"},{"key":"835_CR17","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1162\/jocn.2006.18.2.149","volume":"18","author":"A Fieger","year":"2006","unstructured":"Fieger A, R\u00f6der B, Teder-S\u00e4lej\u00e4rvi W, Hillyard SA, Neville HJ (2006) Auditory spatial tuning in late-onset blindness in humans. J Cogn Neurosci 18:149\u2013157. https:\/\/doi.org\/10.1162\/jocn.2006.18.2.149","journal-title":"J Cogn Neurosci"},{"key":"835_CR18","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1016\/j.heares.2005.01.015","volume":"206","author":"J Fritz","year":"2005","unstructured":"Fritz J, Elhilali M, Shamma S (2005) Active listening: task-dependent plasticity of spectrotemporal receptive fields in primary auditory cortex. Hear Res 206:159\u2013176. https:\/\/doi.org\/10.1016\/j.heares.2005.01.015","journal-title":"Hear Res"},{"key":"835_CR19","doi-asserted-by":"publisher","first-page":"1216","DOI":"10.1038\/nn1141","volume":"6","author":"J Fritz","year":"2003","unstructured":"Fritz J, Shamma S, Elhilali M, Klein D (2003) Rapid task-related plasticity of spectrotemporal receptive fields in primary auditory cortex. Nat Neurosci 6:1216\u20131223. https:\/\/doi.org\/10.1038\/nn1141","journal-title":"Nat Neurosci"},{"key":"835_CR20","doi-asserted-by":"publisher","first-page":"2337","DOI":"10.1152\/jn.00552.2007","volume":"98","author":"JB Fritz","year":"2007","unstructured":"Fritz JB, Elhilali M, Shamma SA (2007) Adaptive changes in cortical receptive fields induced by attention to complex sounds. J Neurophysiol 98:2337\u20132346. https:\/\/doi.org\/10.1152\/jn.00552.2007","journal-title":"J Neurophysiol"},{"key":"835_CR21","doi-asserted-by":"publisher","first-page":"622","DOI":"10.1044\/1092-4388(2010\/10-0052)","volume":"54","author":"S Gordon-Salant","year":"2011","unstructured":"Gordon-Salant S, Friedman SA (2011) Recognition of rapid speech by blind and sighted older adults. J Speech Lang Hear Res 54:622\u2013631. https:\/\/doi.org\/10.1044\/1092-4388(2010\/10-0052)","journal-title":"J Speech Lang Hear Res"},{"issue":"4","key":"835_CR22","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1016\/s0091-6773(74)91975-0","volume":"10","author":"PM Groves","year":"1974","unstructured":"Groves PM, Wilson CJ, Boyle RD (1974) Brain stem pathways, cortical modulation, and habituation of the acoustic startle response. Behav Biol 10(4):391\u2013418. https:\/\/doi.org\/10.1016\/s0091-6773(74)91975-0","journal-title":"Behav Biol"},{"key":"835_CR23","doi-asserted-by":"publisher","unstructured":"He K, Petrus E, Gammon N, Lee HK (2012) Distinct sensory requirements for unimodal and cross-modal homeostatic synaptic plasticity. J Neurosci 32:8469-74. https:\/\/doi.org\/10.1523\/JNEUROSCI.1424-12.2012","DOI":"10.1523\/JNEUROSCI.1424-12.2012"},{"key":"835_CR24","doi-asserted-by":"publisher","first-page":"552","DOI":"10.1152\/jn.00184.2013","volume":"111","author":"AE Hickox","year":"2013","unstructured":"Hickox AE, Liberman MC (2013) Is noise-induced cochlear neuropathy key to the generation of hyperacusis or tinnitus? J Neurophysiol 111:552\u2013564. https:\/\/doi.org\/10.1152\/jn.00184.2013","journal-title":"J Neurophysiol"},{"key":"835_CR25","doi-asserted-by":"publisher","unstructured":"Hoffman HS, Fleshler M (1963) Startle reaction: modification by background acoustic stimulation. Science (80) 141:928-930. https:\/\/doi.org\/10.1126\/science.141.3584.928","DOI":"10.1126\/science.141.3584.928"},{"key":"835_CR26","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1037\/h0022325","volume":"60","author":"HS Hoffman","year":"1965","unstructured":"Hoffman HS, Searle JL (1965) Acoustic variables in the modification of startle reaction in the rat. J Comp Physiol Psychol 60:53\u201358. https:\/\/doi.org\/10.1037\/h0022325","journal-title":"J Comp Physiol Psychol"},{"key":"835_CR27","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1121\/1.1910776","volume":"43","author":"HS Hoffman","year":"1968","unstructured":"Hoffman HS, Searle JL (1968) Acoustic and temporal factors in the evocation of startle. J Acoust Soc Am 43:269\u2013282. https:\/\/doi.org\/10.1121\/1.1910776","journal-title":"J Acoust Soc Am"},{"key":"835_CR28","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1016\/j.cogbrainres.2003.10.015","volume":"19","author":"K Hugdahl","year":"2004","unstructured":"Hugdahl K, Ek M, Takio F, Rintee T, Tuomainen J, Haarala C, H\u00e4m\u00e4l\u00e4inen H (2004) Blind individuals show enhanced perceptual and attentional sensitivity for identification of speech sounds. Cogn Brain Res 19:28\u201332. https:\/\/doi.org\/10.1016\/j.cogbrainres.2003.10.015","journal-title":"Cogn Brain Res"},{"issue":"6","key":"835_CR29","doi-asserted-by":"publisher","first-page":"1133","DOI":"10.1016\/0031-9384(93)90337-f","volume":"54","author":"KP Hunter","year":"1993","unstructured":"Hunter KP, Willott JF (1993) Effects of bilateral lesions of auditory cortex in mice on the acoustic startle response. Physiol Behav 54(6):1133\u20131139. https:\/\/doi.org\/10.1016\/0031-9384(93)90337-f","journal-title":"Physiol Behav"},{"key":"835_CR30","doi-asserted-by":"publisher","unstructured":"Ison JR (1982) Temporal acuity in auditory function in the rat: reflex inhibition by brief gaps in noise. J Comp Physiol Psychol. 96:945-54. https:\/\/doi.org\/10.1037\/0735-7036.96.6.945","DOI":"10.1037\/0735-7036.96.6.945"},{"key":"835_CR31","doi-asserted-by":"crossref","unstructured":"Ison JR (2001) The acoustic startle response: reflex elicitation and reflex modification by preliminary stimuli. In Handbook of Mouse Auditory Research: from Behavior to Molecular Biology (1st ed.), edited by James F. Willott. 59\u201382. CRC Press","DOI":"10.1201\/9781420038736.ch5"},{"key":"835_CR32","doi-asserted-by":"publisher","first-page":"1696","DOI":"10.1121\/1.424382","volume":"104","author":"JR Ison","year":"1998","unstructured":"Ison JR, Agrawal P, Pak J, Vaughn WJ (1998) Changes in temporal acuity with age and with hearing impairment in the mouse: a study of the acoustic startle reflex and its inhibition by brief decrements in noise level. J Acoust Soc Am 104:1696\u20131704. https:\/\/doi.org\/10.1121\/1.424382","journal-title":"J Acoust Soc Am"},{"key":"835_CR33","doi-asserted-by":"publisher","first-page":"522","DOI":"10.1121\/1.1577553","volume":"114","author":"JR Ison","year":"2003","unstructured":"Ison JR, Allen P (2003) A diminished rate of \u2018physiological decay\u2019 at noise offset contributes to age-related changes in temporal acuity in the CBA mouse model of presbycusis. J Acoust Soc Am 114:522\u2013528. https:\/\/doi.org\/10.1121\/1.1577553","journal-title":"J Acoust Soc Am"},{"key":"835_CR34","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1016\/j.bbr.2007.07.014","volume":"185","author":"JR Ison","year":"2007","unstructured":"Ison JR, Allen PD (2007) Pre- but not post-menopausal female CBA\/CaJ mice show less prepulse inhibition than male mice of the same age. Behav Brain Res 185:76\u201381. https:\/\/doi.org\/10.1016\/j.bbr.2007.07.014","journal-title":"Behav Brain Res"},{"issue":"2","key":"835_CR35","doi-asserted-by":"publisher","first-page":"245","DOI":"10.3758\/BF03326721","volume":"6","author":"JR Ison","year":"1978","unstructured":"Ison JR, Silverstein L (1978) Acoustic startle reactions, activity, and background noise intensity, before and after lesions of medial cortex in the rat. Physiol Psychol 6(2):245\u2013248. https:\/\/doi.org\/10.3758\/BF03326721","journal-title":"Physiol Psychol"},{"key":"835_CR36","doi-asserted-by":"publisher","first-page":"3945","DOI":"10.1046\/j.1460-9568.1999.00821.x","volume":"11","author":"AJ King","year":"1999","unstructured":"King AJ, Parsons CH (1999) Improved auditory spatial acuity in visually deprived ferrets. Eur J Neurosci 11:3945\u20133956. https:\/\/doi.org\/10.1046\/j.1460-9568.1999.00821.x","journal-title":"Eur J Neurosci"},{"key":"835_CR37","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3758\/BF03192744","volume":"38","author":"KB Klink","year":"2006","unstructured":"Klink KB, Bendig G, Klump GM (2006) Operant methods for mouse psychoacoustics. Behav Res Methods 38:1\u20137. https:\/\/doi.org\/10.3758\/BF03192744","journal-title":"Behav Res Methods"},{"key":"835_CR38","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1016\/j.neurobiolaging.2020.08.012","volume":"96","author":"A Kobrina","year":"2020","unstructured":"Kobrina A, Schrode KM, Screven LA, Javaid H, Weinberg MM, Brown G, Board R et al (2020) Linking anatomical and physiological markers of auditory system degeneration with behavioral hearing assessments in a mouse (Mus musculus) model of age-related hearing loss. Neurobiol Aging 96:87\u2013103. https:\/\/doi.org\/10.1016\/j.neurobiolaging.2020.08.012","journal-title":"Neurobiol Aging"},{"key":"835_CR39","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/s0166-4328(97)02296-1","volume":"89","author":"M Koch","year":"1997","unstructured":"Koch M, Schnitzler HU (1997) The acoustic startle response in rats\u2014circuits mediating evocation, inhibition and potentiation. Behav Brain Res 89:35\u201349. https:\/\/doi.org\/10.1016\/s0166-4328(97)02296-1","journal-title":"Behav Brain Res"},{"key":"835_CR40","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1016\/j.heares.2014.01.010","volume":"310","author":"AJ Kolarik","year":"2014","unstructured":"Kolarik AJ, Cirstea S, Pardhan S, Moore BCJ (2014) A summary of research investigating echolocation abilities of blind and sighted humans. Hear Res 310:60\u201368. https:\/\/doi.org\/10.1016\/j.heares.2014.01.010","journal-title":"Hear Res"},{"key":"835_CR41","doi-asserted-by":"publisher","first-page":"2098","DOI":"10.1093\/cercor\/bhm233","volume":"18","author":"VC Kotak","year":"2008","unstructured":"Kotak VC, Takesian AE, Sanes DH (2008) Hearing loss prevents the maturation of GABAergic transmission in the auditory cortex. Cereb Cortex 18:2098\u20132108. https:\/\/doi.org\/10.1093\/cercor\/bhm233","journal-title":"Cereb Cortex"},{"issue":"9","key":"835_CR42","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1080\/14992020701383027","volume":"46","author":"A Kral","year":"2007","unstructured":"Kral A (2007) Unimodal and cross-modal plasticity in the \u2018deaf\u2019 auditory cortex. Int J Audiol 46(9):479\u2013493. https:\/\/doi.org\/10.1080\/14992020701383027","journal-title":"Int J Audiol"},{"key":"835_CR43","doi-asserted-by":"publisher","unstructured":"Kupers R, Ptito M (2014) Compensatory plasticity and cross-modal reorganization following early visual deprivation. Neurosci Biobehav Rev 41:36\u201352. https:\/\/doi.org\/10.1016\/j.neubiorev.2013.08.001","DOI":"10.1016\/j.neubiorev.2013.08.001"},{"key":"835_CR44","doi-asserted-by":"crossref","unstructured":"Lamas V, Alvarado JC, Carro J, Merch\u00e1n MA (2013) Long-term evolution of brainstem electrical evoked responses to sound after restricted ablation of the auditory cortex. PLoS One 8(9):e73585.","DOI":"10.1371\/journal.pone.0073585"},{"key":"835_CR45","doi-asserted-by":"publisher","unstructured":"Lauer AM (2017) Minimal effects of age and exposure to a noisy environment on hearing in alpha9 nicotinic receptor knockout mice. Front Neurosci. 11:304. https:\/\/doi.org\/10.3389\/fnins.2017.00304","DOI":"10.3389\/fnins.2017.00304"},{"key":"835_CR46","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1016\/j.neubiorev.2017.03.009","volume":"77","author":"AM Lauer","year":"2017","unstructured":"Lauer AM, Behrens D, Klump G (2017) Acoustic startle modification as a tool for evaluating auditory function of the mouse: progress, pitfalls, and potential. Neurosci Biobehav Rev 77:194\u2013208. https:\/\/doi.org\/10.1016\/j.neubiorev.2017.03.009","journal-title":"Neurosci Biobehav Rev"},{"key":"835_CR47","doi-asserted-by":"crossref","unstructured":"Lauer AM, Dent ML, Sun W, Xu-Friedman MA (2019) Effects of non-traumatic noise and conductive hearing loss on auditory system function. Neurosci 407:182\u2013191. https:\/\/doi.org\/10.1016\/j.neuroscience.2019.01.020","DOI":"10.1016\/j.neuroscience.2019.01.020"},{"key":"835_CR48","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1007\/s10162-011-0262-7","volume":"12","author":"AM Lauer","year":"2011","unstructured":"Lauer AM, May BJ (2011) The medial olivocochlear system attenuates the developmental impact of early noise exposure. J Assoc Res Otolaryngol 12:329\u2013343. https:\/\/doi.org\/10.1007\/s10162-011-0262-7","journal-title":"J Assoc Res Otolaryngol"},{"issue":"5","key":"835_CR49","doi-asserted-by":"publisher","first-page":"901","DOI":"10.1037\/\/0735-7044.99.5.901","volume":"99","author":"RN Leaton","year":"1985","unstructured":"Leaton RN, Cassella JV, Borszcz GS (1985) Short-term and long-term habituation of the acoustic startle response in chronic decerebrate rats. Behav Neurosci 99(5):901\u2013912. https:\/\/doi.org\/10.1037\/\/0735-7044.99.5.901","journal-title":"Behav Neurosci"},{"key":"835_CR50","doi-asserted-by":"publisher","unstructured":"Leaton RN, Supple WF Jr (1986) Cerebellar vermis: essential for long-term habituation of the acoustic startle response. Science (New York, N.Y.), 232(4749):513\u2013515. https:\/\/doi.org\/10.1126\/science.3961494","DOI":"10.1126\/science.3961494"},{"key":"835_CR51","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/j.conb.2015.08.002","volume":"35","author":"H-K Lee","year":"2015","unstructured":"Lee H-K, Whitt JL (2015) Cross-modal synaptic plasticity in adult primary sensory cortices. Curr Opin Neurobiol 35:119\u2013126. https:\/\/doi.org\/10.1016\/j.conb.2015.08.002","journal-title":"Curr Opin Neurobiol"},{"key":"835_CR52","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/j.heares.2018.03.013","volume":"363","author":"RJ Longenecker","year":"2018","unstructured":"Longenecker RJ, Kristaponyte I, Nelson GL, Young JW, Galazyuk AV (2018) Addressing variability in the acoustic startle reflex for accurate gap detection assessment. Hear Res 363:119\u2013135. https:\/\/doi.org\/10.1016\/j.heares.2018.03.013","journal-title":"Hear Res"},{"key":"835_CR53","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1016\/j.brainres.2015.02.012","volume":"1605","author":"B McGuire","year":"2015","unstructured":"McGuire B, Fiorillo B, Ryugo DK, Lauer AM (2015) Auditory nerve synapses persist in ventral cochlear nucleus long after loss of acoustic input in mice with early-onset progressive hearing loss. Brain Res 1605:22\u201330. https:\/\/doi.org\/10.1016\/j.brainres.2015.02.012","journal-title":"Brain Res"},{"key":"835_CR54","doi-asserted-by":"publisher","unstructured":"Meng X, Kao JPY, Lee H-K, Kanold PO (2017) Intracortical circuits in thalamorecipient layers of auditory cortex refine after visual deprivation. Eneuro 4:ENEURO.0092\u20130117. https:\/\/doi.org\/10.1523\/ENEURO.0092-17.2017","DOI":"10.1523\/ENEURO.0092-17.2017"},{"key":"835_CR55","doi-asserted-by":"publisher","first-page":"955","DOI":"10.1016\/j.celrep.2015.07.018","volume":"12","author":"X Meng","year":"2015","unstructured":"Meng X, Kao JPY, Lee H-K, Kanold PO (2015) Visual deprivation causes refinement of intracortical circuits in the auditory cortex. Cell Rep 12:955\u2013964. https:\/\/doi.org\/10.1016\/j.celrep.2015.07.018","journal-title":"Cell Rep"},{"key":"835_CR56","doi-asserted-by":"crossref","unstructured":"Merabet LB, Hamilton R, Schlaug G, Swisher JD, Kiriakopoulos ET, Pitskel NB, Kauffman T et al (2008) Rapid and reversible recruitment of early visual cortex for touch. PLoS One 3:e3046.","DOI":"10.1371\/journal.pone.0003046"},{"key":"835_CR57","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1038\/nrn2758","volume":"11","author":"LB Merabet","year":"2010","unstructured":"Merabet LB, Pascual-Leone A (2010) Neural reorganization following sensory loss: the opportunity of change. Nat Rev Neurosci 11:44\u201352. https:\/\/doi.org\/10.1038\/nrn2758","journal-title":"Nat Rev Neurosci"},{"key":"835_CR58","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1016\/j.neuron.2013.11.023","volume":"81","author":"E Petrus","year":"2014","unstructured":"Petrus E, Isaiah A, Jones AP, Li D, Wang H, Lee H-K, Kanold PO (2014) Crossmodal induction of thalamocortical potentiation leads to enhanced information processing in the auditory cortex. Neuron 81:664\u2013673. https:\/\/doi.org\/10.1016\/j.neuron.2013.11.023","journal-title":"Neuron"},{"key":"835_CR59","doi-asserted-by":"publisher","unstructured":"Petrus E, Rodriguez G, Patterson R, Connor B, Kanold PO, Lee H-K (2015) Vision loss shifts the balance of feedforward and intracortical circuits in opposite directions in mouse primary auditory and visual cortices. J Neurosci 35:8790-8801. https:\/\/doi.org\/10.1523\/JNEUROSCI.4975-14.2015","DOI":"10.1523\/JNEUROSCI.4975-14.2015"},{"key":"835_CR60","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1006\/nlme.1996.0044","volume":"66","author":"PKD Pilz","year":"1996","unstructured":"Pilz PKD, Schnitzler H-U (1996) Habituation and sensitization of the acoustic startle response in rats: amplitude, threshold, and latency measures. Neurobiol Learn Mem 66:67\u201379. https:\/\/doi.org\/10.1006\/nlme.1996.0044","journal-title":"Neurobiol Learn Mem"},{"key":"835_CR61","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1016\/j.bbr.2005.03.022","volume":"162","author":"CF Plappert","year":"2005","unstructured":"Plappert CF, Pilz PKD (2005) Long-term habituation of the startle response in mice evoked by acoustic and tactile stimuli. Behav Brain Res 162:307\u2013310. https:\/\/doi.org\/10.1016\/j.bbr.2005.03.022","journal-title":"Behav Brain Res"},{"key":"835_CR62","unstructured":"R Core Team (2014) R: A language and environment for statistical computing. R foundation for statistical computing, Vienna, Austria. http:\/\/www.R-project.org\/"},{"key":"835_CR63","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1016\/j.beproc.2014.04.016","volume":"106","author":"KE Radziwon","year":"2014","unstructured":"Radziwon KE, Dent ML (2014) Frequency difference limens and auditory cue trading in CBA\/CaJ mice (Mus musculus). Behav Processes 106:74\u201376. https:\/\/doi.org\/10.1016\/j.beproc.2014.04.016","journal-title":"Behav Processes"},{"key":"835_CR64","doi-asserted-by":"publisher","first-page":"961","DOI":"10.1007\/s00359-009-0472-1","volume":"195","author":"KE Radziwon","year":"2009","unstructured":"Radziwon KE, June KM, Stolzberg DJ, Xu-Friedman MA, Salvi RJ, Dent ML (2009) Behaviorally measured audiograms and gap detection thresholds in CBA\/CaJ mice. J Comp Physiol A Neuroethol. sensory, neural. J Comp Physiol A Neuroethol sensory neural Behav Physiol 195:961\u2013969. https:\/\/doi.org\/10.1007\/s00359-009-0472-1","journal-title":"J Comp Physiol A Neuroethol sensory neural Behav Physiol"},{"key":"835_CR65","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1007\/s00221-006-0616-2","volume":"176","author":"A Rao","year":"2007","unstructured":"Rao A, Nobre AC, Alexander I, Cowey A (2007) Auditory evoked visual awareness following sudden ocular blindness: an EEG and TMS investigation. Exp Brain Res 176:288\u2013298. https:\/\/doi.org\/10.1007\/s00221-006-0616-2","journal-title":"Exp Brain Res"},{"key":"835_CR66","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1016\/0166-2236(95)93948-W","volume":"18","author":"JP Rauschecker","year":"1995","unstructured":"Rauschecker JP (1995) Compensatory plasticity and sensory substitution in the cerebral cortex. Trends Neurosci 18:36\u201343. https:\/\/doi.org\/10.1016\/0166-2236(95)93948-W","journal-title":"Trends Neurosci"},{"key":"835_CR67","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1111\/j.1460-9568.1994.tb00256.x","volume":"6","author":"JP Rauschecker","year":"1994","unstructured":"Rauschecker JP, Kniepert U (1994) Auditory localization behaviour in visually deprived cats. Eur J Neurosci 6:149\u2013160. https:\/\/doi.org\/10.1111\/j.1460-9568.1994.tb00256.x","journal-title":"Eur J Neurosci"},{"key":"835_CR68","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1101\/lm.051318.119","volume":"27","author":"EK Rotondo","year":"2020","unstructured":"Rotondo EK, Bieszczad KM (2020) Precise memory for pure tones is predicted by measures of learning-induced sensory system neurophysiological plasticity at cortical and subcortical levels. Learn Mem 27:328\u2013339. https:\/\/doi.org\/10.1101\/lm.051318.119","journal-title":"Learn Mem"},{"key":"835_CR69","doi-asserted-by":"crossref","unstructured":"Sanes DH, Woolley SM (2011) A behavioral framework to guide research on central auditory development and plasticity. Neuron 72(6):912\u2013929. https:\/\/doi.org\/10.1016\/j.neuron.2011.12.005","DOI":"10.1016\/j.neuron.2011.12.005"},{"key":"835_CR70","doi-asserted-by":"crossref","unstructured":"Salloum RH, Yurosko C, Santiago L, Sandridge SA, Kaltenbach JA (2014) Induction of enhanced acoustic startle response by noise exposure: dependence on exposure conditions and testing parameters and possible relevance to hyperacusis. PLoS One 9:e111747.","DOI":"10.1371\/journal.pone.0111747"},{"key":"835_CR71","doi-asserted-by":"publisher","DOI":"10.1111\/desc.13001","volume":"24","author":"M Scheller","year":"2021","unstructured":"Scheller M, Proulx MJ, de Haan M, Dahlmann-Noor A, Petrini K (2021) Late- but not early-onset blindness impairs the development of audio-haptic multisensory integration. Dev Sci 24:e13001. https:\/\/doi.org\/10.1111\/desc.13001","journal-title":"Dev Sci"},{"key":"835_CR72","doi-asserted-by":"publisher","unstructured":"Schrode KM, Muniak MA, Kim Y-H, Lauer AM (2018) Central compensation in auditory brainstem after damaging noise exposure. ENeuro 5:ENEURO.0250\u2013318.\u00a0https:\/\/doi.org\/10.1523\/ENEURO.0250-18.2018","DOI":"10.1523\/ENEURO.0250-18.2018"},{"key":"835_CR73","doi-asserted-by":"publisher","unstructured":"Solarana K, Liu J, Bowen Z, Lee HK, Kanold PO (2019) Temporary visual deprivation causes decorrelation of spatiotemporal population responses in adult mouse auditory cortex. Eneuro 6:ENEURO.0269\u20130319.\u00a0https:\/\/doi.org\/10.1523\/ENEURO.0269-19.2019","DOI":"10.1523\/ENEURO.0269-19.2019"},{"key":"835_CR74","doi-asserted-by":"publisher","unstructured":"Stitt CL, Hoffman HS, Marsh R, Boskoff KJ (1974) Modification of the rat\u2019s startle reaction by an antecedent change in the acoustic environment. J Comp Physiol Psychol. 86:826-36. https:\/\/doi.org\/10.1037\/h0036419","DOI":"10.1037\/h0036419"},{"key":"835_CR75","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1016\/j.heares.2011.08.004","volume":"282","author":"W Sun","year":"2011","unstructured":"Sun W, Manohar S, Jayaram A, Kumaraguru A, Fu Q, Li J, Allman B (2011) Early age conductive hearing loss causes audiogenic seizure and hyperacusis behavior. Hear Res 282:178\u2013183. https:\/\/doi.org\/10.1016\/j.heares.2011.08.004","journal-title":"Hear Res"},{"key":"835_CR76","doi-asserted-by":"publisher","first-page":"134","DOI":"10.3389\/fnsys.2015.00134","volume":"9","author":"G Terreros","year":"2015","unstructured":"Terreros G, Delano PH (2015) Corticofugal modulation of peripheral auditory responses. Front Syst Neurosci 9:134. https:\/\/doi.org\/10.3389\/fnsys.2015.00134","journal-title":"Front Syst Neurosci"},{"key":"835_CR77","doi-asserted-by":"publisher","first-page":"1734","DOI":"10.1016\/j.cub.2004.09.051","volume":"14","author":"P Voss","year":"2004","unstructured":"Voss P, Lassonde M, Gougoux F, Fortin M, Guillemot J-P, Lepore F (2004) Early- and late-onset blind individuals show supra-normal auditory abilities in far-space. Curr Biol 14:1734\u20131738. https:\/\/doi.org\/10.1016\/j.cub.2004.09.051","journal-title":"Curr Biol"},{"key":"835_CR78","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1016\/j.neuropsychologia.2009.08.016","volume":"48","author":"CY Wan","year":"2010","unstructured":"Wan CY, Wood AG, Reutens DC, Wilson SJ (2010) Early but not late-blindness leads to enhanced auditory perception. Neuropsychologia 48:344\u2013348. https:\/\/doi.org\/10.1016\/j.neuropsychologia.2009.08.016","journal-title":"Neuropsychologia"},{"issue":"7","key":"835_CR79","doi-asserted-by":"publisher","first-page":"1325","DOI":"10.1046\/j.1460-9568.2002.02194.x","volume":"16","author":"M Weber","year":"2002","unstructured":"Weber M, Schnitzler HU, Schmid S (2002) Synaptic plasticity in the acoustic startle pathway: the neuronal basis for short-term habituation? Eur J Neurosci 16(7):1325\u20131332. https:\/\/doi.org\/10.1046\/j.1460-9568.2002.02194.x","journal-title":"Eur J Neurosci"},{"key":"835_CR80","doi-asserted-by":"publisher","unstructured":"Wu JS, Yi E, Manca M, Javaid H, Lauer AM, Glowatzki E (2020) Sound exposure dynamically induces dopamine synthesis in cholinergic LOC efferents for feedback to auditory nerve fibers. Elife 9:e52419. https:\/\/doi.org\/10.7554\/eLife.52419","DOI":"10.7554\/eLife.52419"}],"container-title":["Journal of the Association for Research in Otolaryngology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10162-022-00835-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10162-022-00835-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10162-022-00835-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T19:22:43Z","timestamp":1648581763000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10162-022-00835-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,27]]},"references-count":80,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,4]]}},"alternative-id":["835"],"URL":"https:\/\/doi.org\/10.1007\/s10162-022-00835-5","relation":{},"ISSN":["1525-3961","1438-7573"],"issn-type":[{"value":"1525-3961","type":"print"},{"value":"1438-7573","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1,27]]},"assertion":[{"value":"13 August 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 December 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 January 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All experiments were approved by the Johns Hopkins University Animal Care and Use Committee.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}}]}}