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However, variable EEA is an overlooked characteristic that likely plays a role in individual noise-induced hearing loss (NIHL) susceptibility. A noise exposure varying 5\u201319\u00a0dB-A translates to high-EEA individuals theoretically experiencing 3\u20134 times greater NIHL risk than low-EEA individuals.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Objective<\/jats:title>\n                <jats:p>The purpose of this preliminary analysis was to test the hypothesis that higher EEA is correlated with increased\u00a0noise-induced threshold shift susceptibility.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Design<\/jats:title>\n                <jats:p>Nine chinchillas were exposed to 4-kHz octave-band noise at 89\u00a0dB-SPL for 24\u00a0h. Auditory brainstem response thresholds were obtained pre-exposure, 24-h post-exposure, and 4-week post-exposure. Relationships between EEA and threshold shift were analyzed.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Open-ear EEA ranged 11\u201319\u00a0dB-SPL, and occluded-ear EEA ranged 10\u201321\u00a0dB-SPL. Higher occluded-ear EEA was correlated with increased NIHL susceptibility (<jats:italic>p<\/jats:italic>\u2009=\u20090.04), as was lower body weight (<jats:italic>p<\/jats:italic>\u2009=\u20090.01). Male animals exhibited more threshold shift than female animals (<jats:italic>p<\/jats:italic>\u2009=\u20090.02), lower body weight than female animals (<jats:italic>p<\/jats:italic>\u2009=\u20090.02), and higher occluded-ear EEA (male mean\u2009=\u200918\u00a0dB; female mean\u2009=\u200915\u00a0dB).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Taken together, increased threshold shift susceptibility was observed in the smallest animals, animals with the highest occluded-ear EEA, and in male animals (which tended to have higher occluded-ear EEA). Given the established relationship between smaller body size and higher occluded-ear EEA, these preliminary results suggest that body size (and occluded-ear EEA; a function of body size) could be a potential, underlying driver of NIHL susceptibility differences, rather than true sex differences.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s10162-023-00913-2","type":"journal-article","created":{"date-parts":[[2023,11,27]],"date-time":"2023-11-27T15:03:08Z","timestamp":1701097388000},"page":"563-574","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Noise-Induced Hearing Threshold Shift Correlated with Body Weight and External-Ear Amplification in Chinchilla: a Preliminary Analysis"],"prefix":"10.1007","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6491-5857","authenticated-orcid":false,"given":"Sarah K.","family":"Grinn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica","family":"Trevino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward","family":"Lobarinas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,11,27]]},"reference":[{"key":"913_CR1","doi-asserted-by":"crossref","unstructured":"Burns W, Robinson DW (1970) An investigation of the effects of occupational noise on hearing. 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