{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T16:23:50Z","timestamp":1762100630859},"reference-count":47,"publisher":"Oxford University Press (OUP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mod Rheumatol"],"published-print":{"date-parts":[[2007,2,20]]},"DOI":"10.1007\/s10165-006-0531-1","type":"journal-article","created":{"date-parts":[[2007,2,3]],"date-time":"2007-02-03T06:55:52Z","timestamp":1170485752000},"page":"17-23","source":"Crossref","is-referenced-by-count":14,"title":["Scientific basis for the efficacy of combined use of antirheumatic drugs against bone destruction in rheumatoid arthritis"],"prefix":"10.1093","volume":"17","author":[{"given":"Ayako","family":"Suematsu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuhito","family":"Tajiri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoki","family":"Nakashima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junko","family":"Taka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sae","family":"Ochi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiromi","family":"Oda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kozo","family":"Nakamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sakae","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Takayanagi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2007,2,20]]},"reference":[{"key":"531_CR1","doi-asserted-by":"crossref","first-page":"225","DOI":"10.3109\/s10165-005-0398-6","volume":"15","author":"H Takayanagi","year":"2005","journal-title":"Mod Rheumatol"},{"key":"531_CR2","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1038\/nature01661","volume":"423","author":"GS Firestein","year":"2003","journal-title":"Nature"},{"key":"531_CR3","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1097\/01.bor.0000231912.24740.a5","volume":"18","author":"K Sato","year":"2006","journal-title":"Curr Opin Rheumatol"},{"key":"531_CR4","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1111\/j.1600-0765.2005.00814.x","volume":"40","author":"H Takayanagi","year":"2005","journal-title":"J Periodontal Res"},{"key":"531_CR5","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1038\/nrd1109","volume":"2","author":"JS Smolen","year":"2003","journal-title":"Nat Rev Drug Discov"},{"key":"531_CR6","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1136\/ard.2005.035436","volume":"65","author":"X Le Loet","year":"2006","journal-title":"Ann Rheum Dis"},{"key":"531_CR7","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1136\/ard.58.4.220","volume":"58","author":"M Dougados","year":"1999","journal-title":"Ann Rheum Dis"},{"key":"531_CR8","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/S0140-6736(04)15640-7","volume":"363","author":"L Klareskog","year":"2004","journal-title":"Lancet"},{"issue":"8","key":"531_CR9","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1038\/nrg1122","volume":"4","author":"SL Teitelbaum","year":"2003","journal-title":"Nat Rev Genet"},{"key":"531_CR10","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1038\/nature01658","volume":"423","author":"WJ Boyle","year":"2003","journal-title":"Nature"},{"key":"531_CR11","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1210\/edrv.20.3.0367","volume":"20","author":"T Suda","year":"1999","journal-title":"Endocr Rev"},{"key":"531_CR12","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1146\/annurev.immunol.20.100301.064753","volume":"20","author":"LE Theill","year":"2002","journal-title":"Annu Rev Immunol"},{"key":"531_CR13","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1007\/s00109-004-0612-6","volume":"83","author":"H Takayanagi","year":"2005","journal-title":"J Mol Med"},{"key":"531_CR14","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1038\/nature02444","volume":"428","author":"T Koga","year":"2004","journal-title":"Nature"},{"key":"531_CR15","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1111\/j.0105-2896.2005.00331.x","volume":"208","author":"FP Ross","year":"2005","journal-title":"Immunol Rev"},{"key":"531_CR16","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1146\/annurev.immunol.24.021605.090646","volume":"24","author":"MC Walsh","year":"2006","journal-title":"Annu Rev Immunol"},{"key":"531_CR17","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1016\/S1534-5807(02)00369-6","volume":"3","author":"H Takayanagi","year":"2002","journal-title":"Dev Cell"},{"key":"531_CR18","doi-asserted-by":"crossref","first-page":"3597","DOI":"10.1073\/pnas.95.7.3597","volume":"95","author":"H Yasuda","year":"1998","journal-title":"Proc Natl Acad Sci USA"},{"key":"531_CR19","doi-asserted-by":"crossref","first-page":"2600","DOI":"10.1210\/endo-123-5-2600","volume":"123","author":"N Takahashi","year":"1988","journal-title":"Endocrinology"},{"key":"531_CR20","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1002\/art.20206","volume":"50","author":"M Urushibara","year":"2004","journal-title":"Arthritis Rheum"},{"key":"531_CR21","doi-asserted-by":"crossref","first-page":"2143","DOI":"10.1002\/1529-0131(200010)43:10<2143::AID-ANR1>3.0.CO;2-S","volume":"43","author":"EM Gravallese","year":"2000","journal-title":"Arthritis Rheum"},{"key":"531_CR22","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1002\/1529-0131(200002)43:2<259::AID-ANR4>3.0.CO;2-W","volume":"43","author":"H Takayanagi","year":"2000","journal-title":"Arthritis Rheum"},{"key":"531_CR23","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1006\/bbrc.1997.7404","volume":"240","author":"H Takayanagi","year":"1997","journal-title":"Biochem Biophys Res Commun"},{"key":"531_CR24","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.1016\/S0002-9440(10)63016-7","volume":"159","author":"AR Pettit","year":"2001","journal-title":"Am J Pathol"},{"key":"531_CR25","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1172\/JCI0215582","volume":"110","author":"K Redlich","year":"2002","journal-title":"J Clin Invest"},{"key":"531_CR26","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1172\/JCI6093","volume":"104","author":"H Takayanagi","year":"1999","journal-title":"J Clin Invest"},{"key":"531_CR27","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1038\/46303","volume":"402","author":"YY Kong","year":"1999","journal-title":"Nature"},{"key":"531_CR28","doi-asserted-by":"crossref","first-page":"1697","DOI":"10.1172\/JCI7739","volume":"105","author":"E Lubberts","year":"2000","journal-title":"J Clin Invest"},{"key":"531_CR29","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.1002\/art.21762","volume":"54","author":"P Ranganathan","year":"2006","journal-title":"Arthritis Rheum"},{"key":"531_CR30","doi-asserted-by":"crossref","first-page":"85","DOI":"10.3109\/s10165-005-0466-y","volume":"16","author":"N Sekiguchi","year":"2006","journal-title":"Mod Rheumatol"},{"key":"531_CR31","first-page":"27","volume":"23","author":"M Nagashima","year":"2005","journal-title":"Clin Exp Rheumatol"},{"key":"531_CR32","unstructured":"Tsuji F, Aono H, Okamoto M, Sasano M. Bucillamine, A unique anti-rheumatic drug. Curr Top Pharmacol [in press]"},{"key":"531_CR33","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1038\/35046102","volume":"408","author":"H Takayanagi","year":"2000","journal-title":"Nature"},{"key":"531_CR34","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1038\/nm1270","volume":"11","author":"T Koga","year":"2005","journal-title":"Nat Med"},{"key":"531_CR35","doi-asserted-by":"crossref","first-page":"3831","DOI":"10.1002\/art.20637","volume":"50","author":"CK Lee","year":"2004","journal-title":"Arthritis Rheum"},{"key":"531_CR36","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1084\/jem.20051150","volume":"202","author":"M Asagiri","year":"2005","journal-title":"J Exp Med"},{"key":"531_CR37","doi-asserted-by":"crossref","first-page":"2673","DOI":"10.1084\/jem.20061775","volume":"203","author":"K Sato","year":"2006","journal-title":"J Exp Med"},{"key":"531_CR38","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1002\/art.1780270902","volume":"27","author":"M Bromley","year":"1984","journal-title":"Arthritis Rheum"},{"key":"531_CR39","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1038\/ncprheum0036","volume":"1","author":"G Schett","year":"2005","journal-title":"Nat Clin Pract Rheumatol"},{"key":"531_CR40","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1038\/nri1807","volume":"6","author":"C Dong","year":"2006","journal-title":"Nat Rev Immunol"},{"key":"531_CR41","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1002\/1529-0131(200007)43:7<1616::AID-ANR27>3.0.CO;2-I","volume":"43","author":"Y Munakata","year":"2000","journal-title":"Arthritis Rheum"},{"key":"531_CR42","first-page":"65","volume":"23","author":"H Aono","year":"1996","journal-title":"J Rheumatol"},{"key":"531_CR43","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1038\/sj.bjp.0702937","volume":"128","author":"S Liptay","year":"1999","journal-title":"Br J Pharmacol"},{"key":"531_CR44","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1136\/ard.2003.013961","volume":"63","author":"FC Breedveld","year":"2004","journal-title":"Ann Rheum Dis"},{"key":"531_CR45","doi-asserted-by":"crossref","first-page":"323","DOI":"10.3109\/s10165-005-0420-z","volume":"15","author":"Y Ichikawa","year":"2005","journal-title":"Mod Rheumatol"},{"key":"531_CR46","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1056\/NEJM200103223441207","volume":"344","author":"EH Choy","year":"2001","journal-title":"N Engl J Med"},{"key":"531_CR47","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1146\/annurev.immunol.19.1.163","volume":"19","author":"M Feldmann","year":"2001","journal-title":"Annu Rev Immunol"}],"container-title":["Modern Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.springerlink.com\/index\/pdf\/10.1007\/s10165-006-0531-1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,9]],"date-time":"2022-03-09T16:24:50Z","timestamp":1646843090000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10165-006-0531-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,2,20]]},"references-count":47,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,2,20]]}},"alternative-id":["531"],"URL":"https:\/\/doi.org\/10.1007\/s10165-006-0531-1","relation":{},"ISSN":["1439-7595","1439-7609"],"issn-type":[{"value":"1439-7595","type":"print"},{"value":"1439-7609","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,2,20]]}}}