{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T05:17:07Z","timestamp":1783487827643,"version":"3.55.0"},"reference-count":54,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2008,10,25]],"date-time":"2008-10-25T00:00:00Z","timestamp":1224892800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/2.0"},{"start":{"date-parts":[[2008,10,25]],"date-time":"2008-10-25T00:00:00Z","timestamp":1224892800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/2.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Orthopaed Traumatol"],"published-print":{"date-parts":[[2008,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Osteolytic lesions are common radiological findings behind acetabular prosthetic cups. If the cup is well-fixed, the management is quite controversial. Although implant exchange is the most reliable procedure, in most cases it could be considered overtreatment, with the potential for further morbidity and bone loss. Liner exchange associated with lesion debridement and grafting represents an alternative option that is less invasive. Here we present our experiences from a small pilot study of minimally invasive osteolysis treatment without bearings exchange in patients with no evidence of liner wear.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>Inclusion criteria: retroacetabular osteolytic lesions in ceramic-on-polyethylene or metal-on-polyethylene cementless total hip arthroplasties, affecting more than 50% of the bone\u2013prosthesis interface on anteroposterior radiography. Exclusion criteria: head penetration into the liner, suspected loosening or infection. Six patients were selected, two asymptomatic and four symptomatic. Only the symptomatic patients accepted the proposed treatment (performed between June 2004 and March 2006). All of them received fluoroscopy-assisted lesion debridement through an iliac cortical window, morcellized bone allograft mixed with autologous platelet-rich plasma, joint exploration for culture and lavage through a small capsular window. Patients were followed up clinically and radiologically at six\u00a0months, 12\u00a0months, and then yearly.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Three patients out of four showed clinical and radiological improvement. One showed radiological improvement only, and recently underwent cup exchange for subsequent loosening. The visual analog scale (VAS) values for pain decreased on average, but not significantly. No major complications occurred. No recurrence was noted at 2.25-\u00a0years-follow-up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Although the small series does not allow any absolute conclusions to be drawn, the reported results seem to justify further, wider studies. It is still unclear if osteolytic lesions associated with no wear of the poly liner would progress to implant failure if left untreated. Until the problem is better understood, this procedure might represent an interesting way to prevent potential loosening and severe bone loss in intact sockets.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s10195-008-0031-5","type":"journal-article","created":{"date-parts":[[2008,10,24]],"date-time":"2008-10-24T13:36:17Z","timestamp":1224855377000},"page":"225-231","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Retroacetabular osteolytic lesions behind well-fixed prosthetic cups: pilot study of bearings-retaining surgery"],"prefix":"10.1007","volume":"9","author":[{"given":"Luca","family":"Pierannunzii","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florian","family":"Fischer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"d\u2019Imporzano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2008,10,25]]},"reference":[{"issue":"Suppl","key":"31_CR1","doi-asserted-by":"crossref","first-page":"116","DOI":"10.2106\/00004623-200200002-00016","volume":"84A","author":"SD Stulberg","year":"2002","unstructured":"Stulberg SD, Wixson RL, Adams AD, Hendrix RW, Bernfield JB (2002) Monitoring pelvic osteolysis following total hip replacement surgery: an algorithm for surveillance. J Bone Joint Surg 84A(Suppl):116\u2013122","journal-title":"J Bone Joint Surg"},{"key":"31_CR2","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1097\/00003086-200112000-00007","volume":"393","author":"WH Harris","year":"2001","unstructured":"Harris WH (2001) Wear and periprosthetic osteolysis: the problem. Clin Orthop 393:66\u201370","journal-title":"Clin Orthop"},{"key":"31_CR3","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1097\/00003086-200112000-00008","volume":"393","author":"JJ Jacobs","year":"2001","unstructured":"Jacobs JJ, Roebuck KA, Archibeck M, Hallab NJ, Glant TT (2001) Osteolysis: basic science. Clin Orthop 393:71\u201377","journal-title":"Clin Orthop"},{"key":"31_CR4","first-page":"307","volume":"47","author":"RK Sinha","year":"1998","unstructured":"Sinha RK, Shanbhag AS, Maloney WJ, Hasselman CT, Rubash HE (1998) Osteolysis: cause and effect. Instr Course Lect 47:307\u2013320","journal-title":"Instr Course Lect"},{"key":"31_CR5","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/0267-6605(91)90057-M","volume":"7","author":"A Pizzoferrato","year":"1991","unstructured":"Pizzoferrato A, Ciapetti G, Stea S, Toni A (1991) Cellular events in the mechanisms of prosthesis loosening. Clin Mater 7:51\u201381","journal-title":"Clin Mater"},{"key":"31_CR6","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1302\/0301-620X.72B6.2246301","volume":"72","author":"S Santavirta","year":"1990","unstructured":"Santavirta S, Holkka V, Eskola A, Kontinen YT, Paavilainen T, Tallroth K (1990) Aggressive granulomatous lesions in cementless total hip arthroplasty. J Bone Joint Surg Br 72:980\u2013984","journal-title":"J Bone Joint Surg Br"},{"key":"31_CR7","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1016\/S0142-9612(02)00510-0","volume":"24","author":"A Hatton","year":"2003","unstructured":"Hatton A, Nevelos JE, Matthews JB, Fisher J, Ingham E (2003) Effects of clinically relevant alumina ceramic wear particles on TNF-a production by human peripheral blood mononuclear cells. Biomaterials 24:1193\u20131204","journal-title":"Biomaterials"},{"key":"31_CR8","doi-asserted-by":"crossref","first-page":"2499","DOI":"10.2106\/00004623-200711000-00025","volume":"89","author":"KW Nam","year":"2007","unstructured":"Nam KW, Yoo JJ, Kim YL, Kim YM, Lee MH, Kim HJ (2007) Alumina-debris-induced osteolysis in contemporary alumina-on-alumina total hip arthroplasty: a case report. J Bone Joint Surg Am 89:2499\u20132503","journal-title":"J Bone Joint Surg Am"},{"key":"31_CR9","first-page":"1171","volume":"88","author":"JJ Jacobs","year":"2006","unstructured":"Jacobs JJ, Hallab NJ (2006) Loosening and osteolysis associated with metal-on-metal bearings: a local effect of metal hypersensitivity? J Bone Joint Surg Am 88:1171\u20131172","journal-title":"J Bone Joint Surg Am"},{"key":"31_CR10","first-page":"171","volume":"45","author":"WJ Maloney","year":"1996","unstructured":"Maloney WJ, Smith RL (1996) Periprosthetic osteolysis in total hip arthroplasty: the role of particulate wear debris. Instr Course Lect 45:171\u2013182","journal-title":"Instr Course Lect"},{"key":"31_CR11","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.2106\/00004623-199509000-00002","volume":"77","author":"WJ Maloney","year":"1994","unstructured":"Maloney WJ, Smith RL, Hvene D, Schmalzried TP, Rubash H (1994) Isolation and characterization of wear debris generated in patients who have had failure of a hip arthroplasty without cement. J Bone Joint Surg Am 77:1301\u20131310","journal-title":"J Bone Joint Surg Am"},{"key":"31_CR12","doi-asserted-by":"crossref","first-page":"3540","DOI":"10.1073\/pnas.96.7.3540","volume":"96","author":"H Hsu","year":"1999","unstructured":"Hsu H, Lacey DL, Dunstan CR et al (1999) Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand. Proc Natl Acad Sci USA 96:3540\u20133545","journal-title":"Proc Natl Acad Sci USA"},{"key":"31_CR13","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1083\/jcb.145.3.527","volume":"145","author":"TL Burgess","year":"1999","unstructured":"Burgess TL, Qian Y, Kaufman S et al (1999) The ligand for osteoprotegerin (OPGL) directly activates mature osteoclasts. J Cell Biol 145:527\u2013538","journal-title":"J Cell Biol"},{"key":"31_CR14","doi-asserted-by":"crossref","first-page":"3597","DOI":"10.1073\/pnas.95.7.3597","volume":"95","author":"H Yasuda","year":"1998","unstructured":"Yasuda H, Shima N, Nakagawa N, Yamaguchi K, Kinosaki M, Mochizuki SI (1998) Osteoclast differentiation factor is a ligand for osteoprotegerin\/osteoclastogenesis-inhibitory factor and is identical to TRANCE\/RANKL. Proc Natl Acad Sci USA 95:3597\u20133602","journal-title":"Proc Natl Acad Sci USA"},{"key":"31_CR15","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1097\/BLO.0b013e31804b4147","volume":"460","author":"G Holt","year":"2007","unstructured":"Holt G, Murnaghan C, Reilly J, Meek RMD (2007) The biology of aseptic osteolysis. Clin Orthop 460:240\u2013252","journal-title":"Clin Orthop"},{"key":"31_CR16","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.2106\/00004623-200306000-00018","volume":"85","author":"KF Orishimo","year":"2003","unstructured":"Orishimo KF, Claus AM, Sychterz CJ, Engh CA (2003) Relationship between polyethylene wear and osteolysis in hips with a second generation porous-coated cementless cup after seven years of follow-up. J Bone Joint Surg Am 85:1095\u20131099","journal-title":"J Bone Joint Surg Am"},{"key":"31_CR17","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1054\/arth.2002.33664","volume":"17","author":"JH Dumbleton","year":"2002","unstructured":"Dumbleton JH, Manley MT, Edidin AA (2002) A literature review of the association between wear rate and osteolysis in total hip arthroplasty. J Arthroplasty 17:649\u2013661","journal-title":"J Arthroplasty"},{"key":"31_CR18","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1097\/00003086-199906000-00018","volume":"363","author":"DH Sochart","year":"1999","unstructured":"Sochart DH (1999) Relationship of acetabular wear to osteolysis and loosening in total hip arthroplasty. Clin Orthop 363:135\u2013150","journal-title":"Clin Orthop"},{"key":"31_CR19","doi-asserted-by":"crossref","unstructured":"Olyslaegers C, Defoort K, Simon JP, Vandenberghe L (2008) Wear in conventional and highly cross-linked polyethylene cups: a 5-year follow-up study. J Arthroplasty 23(4):489\u2013494","DOI":"10.1016\/j.arth.2007.02.013"},{"issue":"4","key":"31_CR20","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/j.arth.2004.09.058","volume":"20","author":"WY Shon","year":"2005","unstructured":"Shon WY, Baldini T, Peterson MG, Wright TM, Salvati EA (2005) Impingement in total hip arthroplasty: a study of retrieved acetabular components. J Arthroplasty 20(4):427\u2013435","journal-title":"J Arthroplasty"},{"issue":"4","key":"31_CR21","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.arth.2004.02.019","volume":"19","author":"DDR Naudie","year":"2004","unstructured":"Naudie DDR, Engh CA (2004) Surgical management of polyethylene wear and pelvic osteolysis with modular uncemented acetabular components. J Arthroplasty 19(4):124\u2013129","journal-title":"J Arthroplasty"},{"key":"31_CR22","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1097\/01.blo.0000096816.78689.e5","volume":"417","author":"PP Chiang","year":"2003","unstructured":"Chiang PP, Burke DW, Freiberg AA, Rubash HE (2003) Osteolysis of the pelvis: evaluation and treatment. Clin Orthop 417:164\u2013174","journal-title":"Clin Orthop"},{"issue":"7","key":"31_CR23","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1016\/j.arth.2007.05.049","volume":"22","author":"JD Chang","year":"2007","unstructured":"Chang JD, Yoo JH, Hur M, Lee SS, Chung YK, Lee CJ (2007) Revision total hip arthroplasty for pelvic osteolysis with well-fixed cementless cup. J Arthroplasty 22(7):987\u2013992","journal-title":"J Arthroplasty"},{"key":"31_CR24","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1016\/S0883-5403(96)80175-6","volume":"11","author":"WJ Hozack","year":"1996","unstructured":"Hozack WJ, Mesa JJ, Carey C, Rothman RH (1996) Relationship between polyethylene wear, pelvic osteolysis, and clinical symptomatology in patients with cementless acetabular components: a framework for decision making. J Arthroplasty 11:769\u2013772","journal-title":"J Arthroplasty"},{"key":"31_CR25","doi-asserted-by":"crossref","first-page":"159","DOI":"10.3928\/0147-7447-19960201-11","volume":"19","author":"BF Kavanagh","year":"1996","unstructured":"Kavanagh BF, Callaghan JJ, Leggon R, Heekin RD, Wold L (1996) Pelvic osteolysis associated with an uncemented acetabular component in total hip arthroplasty. Orthopedics 19:159\u2013163","journal-title":"Orthopedics"},{"key":"31_CR26","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1097\/BLO.0b013e3181576097","volume":"465","author":"CA Engh Jr","year":"2007","unstructured":"Engh CA Jr, Egawa H, Beykirch SE, Hopper RH Jr, Engh CA (2007) The quality of osteolysis grafting with cementless acetabular component retention. Clin Orthop 465:150\u2013154","journal-title":"Clin Orthop"},{"key":"31_CR27","doi-asserted-by":"crossref","first-page":"1628","DOI":"10.2106\/00004623-199711000-00003","volume":"79","author":"WJ Maloney","year":"1997","unstructured":"Maloney WJ, Herzwurm P, Paprosky W, Rubash HE, Engh CA (1997) Treatment of pelvic osteolysis associated with a stable acetabular component inserted without cement as part of a total hip replacement. J Bone Joint Surg Am 79:1628\u20131634","journal-title":"J Bone Joint Surg Am"},{"key":"31_CR28","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1097\/00003086-199805000-00018","volume":"350","author":"TP Schmalzried","year":"1998","unstructured":"Schmalzried TP, Fowble VA, Amstutz HC (1998) The fate of pelvic osteolysis after reoperation: no recurrence with lesional treatment. Clin Orthop 350:128\u2013137","journal-title":"Clin Orthop"},{"key":"31_CR29","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1097\/00003086-200112000-00009","volume":"393","author":"WJ Maloney","year":"2001","unstructured":"Maloney WJ, Paprosky W, Engh CA, Rubash H (2001) Surgical treatment of pelvic osteolysis. Clin Orthop 393:78\u201384","journal-title":"Clin Orthop"},{"key":"31_CR30","doi-asserted-by":"crossref","first-page":"1803","DOI":"10.2106\/00004623-200112000-00006","volume":"83","author":"D Pollock","year":"2001","unstructured":"Pollock D, Sychterz CJ, Engh CA (2001) A clinically practical method of manually assessing polyethylene liner thickness. J Bone Joint Surg Am 83:1803\u20131809","journal-title":"J Bone Joint Surg Am"},{"key":"31_CR31","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1302\/0301-620X.81B2.9334","volume":"81","author":"DG Southwell","year":"1999","unstructured":"Southwell DG, Bechtold JE, Lew WD, Schmidt AH (1999) Improving the detection of acetabular osteolysis using oblique radiographs. J Bone Joint Surg Br 81:289\u2013295","journal-title":"J Bone Joint Surg Br"},{"key":"31_CR32","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1054\/arth.2000.4330","volume":"15","author":"RH Zimlich","year":"2000","unstructured":"Zimlich RH, Fehring TK (2000) Underestimation of pelvic osteolysis: the value of an iliac oblique radiograph. J Arthroplasty 15:796\u2013801","journal-title":"J Arthroplasty"},{"key":"31_CR33","doi-asserted-by":"crossref","unstructured":"Claus AM, Engh CA Jr, Sychterz CJ et al (2003) Radiographic definition of pelvic osteolysis following total hip arthroplasty. J Bone Joint Surg Am 85:1519\u20131526","DOI":"10.2106\/00004623-200308000-00013"},{"key":"31_CR34","doi-asserted-by":"crossref","first-page":"40","DOI":"10.2106\/00004623-194931010-00003","volume":"31","author":"MN Smith-Petersen","year":"1949","unstructured":"Smith-Petersen MN (1949) Approach to and exposure of the hip joint for mold arthroplasty. J Bone Joint Surg Am 31:40\u201346","journal-title":"J Bone Joint Surg Am"},{"issue":"6","key":"31_CR35","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1016\/S1079-2104(98)90029-4","volume":"85","author":"RE Marx","year":"1998","unstructured":"Marx RE, Carlson ER, Eichstaedt RM, Schimmele SR, Strauss JE, Georgeff KR (1998) Platelet-rich plasma: growth factor enhancement for bone grafts. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 85(6):638\u2013646","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"issue":"5","key":"31_CR36","doi-asserted-by":"crossref","first-page":"509","DOI":"10.3727\/000000003108747073","volume":"12","author":"M Yazawa","year":"2003","unstructured":"Yazawa M, Ogata H, Nakajima T, Mori T, Watanabe N, Handa M (2003) Basic studies on the clinical applications of platelet-rich plasma. Cell Transplant 12(5):509\u2013518","journal-title":"Cell Transplant"},{"key":"31_CR37","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1080\/000164700317362154","volume":"71","author":"L Linder","year":"2000","unstructured":"Linder L (2000) Cancellous impaction grafting in the human femur: histological and radiographic observations in 6 autopsy femurs and 8 biopsies. Acta Orthop Scand 71:543\u2013552","journal-title":"Acta Orthop Scand"},{"issue":"5","key":"31_CR38","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1302\/0301-620X.90B5.20545","volume":"90","author":"S Glyn-Jones","year":"2008","unstructured":"Glyn-Jones S, McLardy-Smith P, Gill HS, Murray DW (2008) The creep and wear of highly cross-linked polyethylene: a three-year randomised, controlled trial using radiostereometric analysis. J Bone Joint Surg Br 90(5):556\u2013561","journal-title":"J Bone Joint Surg Br"},{"issue":"3","key":"31_CR39","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1002\/jor.20042","volume":"24","author":"JR Penmetsa","year":"2006","unstructured":"Penmetsa JR, Laz PJ, Petrella AJ, Rullkoetter PJ (2006) Influence of polyethylene creep behavior on wear in total hip arthroplasty. J Orthop Res 24(3):422\u2013427","journal-title":"J Orthop Res"},{"key":"31_CR40","doi-asserted-by":"crossref","first-page":"821","DOI":"10.2106\/00004623-199906000-00009","volume":"81","author":"CJ Sychterz","year":"1999","unstructured":"Sychterz CJ, Engh A Jr, Yang A, Engh CA (1999) Analysis of temporal wear patterns of porous-coated acetabular components: distinguishing between true wear and so-called bedding-in. J Bone Joint Surg Am 81:821\u2013830","journal-title":"J Bone Joint Surg Am"},{"issue":"2","key":"31_CR41","first-page":"145","volume":"14","author":"XQ Hu","year":"2004","unstructured":"Hu XQ, Isaac GH, Fisher J (2004) Changes in the contact area during the bedding-in wear of different sizes of metal on metal hip prosthesis. Biomed Mater Eng 14(2):145\u2013149","journal-title":"Biomed Mater Eng"},{"issue":"6","key":"31_CR42","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1080\/17453670710014518","volume":"78","author":"G Digas","year":"2007","unstructured":"Digas G, K\u00e4rrholm J, Thanner J, Herberts P (2007) 5-year experience of highly crosslinked polyethylene in cemented and uncemented sockets: two randomized studies using radiostereometric analysis. Acta Orthopaedica 78(6):746\u2013754","journal-title":"Acta Orthopaedica"},{"issue":"6","key":"31_CR43","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.arth.2007.03.009","volume":"22","author":"C Bragdon","year":"2007","unstructured":"Bragdon C, Greene M, Freiberg A, Harris W, Malchau H (2007) Radiostereometric analysis comparison of wear of highly cross-linked polyethylene against 36- vs 28-mm femoral heads. J Arthroplasty 22(6):125\u2013129","journal-title":"J Arthroplasty"},{"key":"31_CR44","first-page":"1816","volume":"87","author":"LD Dorr","year":"2005","unstructured":"Dorr LD, Wan Z, Shahrdar C, Sirianni L, Boutary M, Yun A (2005) Clinical performance of a Durasul highly cross-linked polyethylene acetabular liner for total hip arthroplasty at five years. J Bone Joint Surg Am 87:1816\u20131821","journal-title":"J Bone Joint Surg Am"},{"key":"31_CR45","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.arth.2006.05.002","volume":"21","author":"CA Engh Jr","year":"2006","unstructured":"Engh CA Jr, Stepniewski AS, Ginn SD, Beykirch SE, Sychterz-Terefenko CJ, Hopper RH Jr, Engh CA (2006) A randomized prospective evaluation of outcomes after total hip arthroplasty using cross-linked Marathon and noncross-linked Enduron polyethylene liners. J Arthroplasty 21:17\u201325","journal-title":"J Arthroplasty"},{"key":"31_CR46","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1097\/00003086-200512000-00024","volume":"441","author":"JA D\u2019Antonio","year":"2005","unstructured":"D\u2019Antonio JA, Manley MT, Capello WN, Bierbaum BE, Ramakrishnan R, Naughton M, Sutton K (2005) Five-year experience with crossfire highly cross-linked polyethylene. Clin Orthop 441:143\u2013150","journal-title":"Clin Orthop"},{"key":"31_CR47","doi-asserted-by":"crossref","unstructured":"Usrey MM, Noble PC, Rudner LJ, Conditt MA et al (2006) Does neck\/liner impingement increase wear of ultrahigh-molecular-weight polyethylene liners? J Arthroplasty 21(6 Suppl 2):65\u201371","DOI":"10.1016\/j.arth.2006.05.013"},{"issue":"2","key":"31_CR48","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.arth.2005.01.025","volume":"22","author":"M Kigman","year":"2007","unstructured":"Kigman M, Furman BD, Padgett DE, Wright TM (2007) Impingement contributes to backside wear and screw-metallic shell fretting in modular acetabular cups. J Arthroplasty 22(2):258\u2013264","journal-title":"J Arthroplasty"},{"key":"31_CR49","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1097\/01.blo.0000177719.16146.33","volume":"440","author":"AG Della Valle","year":"2005","unstructured":"Della Valle AG, Rana A, Furman B, Sculco TP, Salvati EA (2005) Backside wear is low in retrieved modern, modular, and nonmodular acetabular liners. Clin Orthop 440:184\u2013191","journal-title":"Clin Orthop"},{"issue":"2","key":"31_CR50","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1054\/jcms.2002.0285","volume":"30","author":"G Weibrich","year":"2002","unstructured":"Weibrich G, Kleis WKG, Hafner G, Hitzler WE (2002) Growth factor levels in platelet-rich plasma and correlations with donor age, sex, and platelet count. J Craniomaxillofac Surg 30(2):97\u2013102","journal-title":"J Craniomaxillofac Surg"},{"issue":"2","key":"31_CR51","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1080\/08977190290031950","volume":"20","author":"G Weibrich","year":"2002","unstructured":"Weibrich G, Buch RS, Kleis WK, Hafner G, Hitzler WE, Wagner W (2002) Quantification of thrombocyte growth factors in platelet concentrates produced by discontinuous cell separation. Growth Factors 20(2):93\u201397","journal-title":"Growth Factors"},{"issue":"6","key":"31_CR52","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1902\/jop.2003.74.6.849","volume":"74","author":"K Okuda","year":"2003","unstructured":"Okuda K, Kawase T, Momose M, Murata M, Saito Y, Suzuki H, Wolff LF, Yoshie H (2003) Platelet-rich plasma contains high levels of platelet-derived growth factor and transforming growth factor-beta and modulates the proliferation of periodontally related cells in vitro. J Periodontol 74(6):849\u2013857","journal-title":"J Periodontol"},{"issue":"3","key":"31_CR53","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1080\/17453670710015364","volume":"79","author":"O Wahlstr\u00f6m","year":"2008","unstructured":"Wahlstr\u00f6m O, Linder C, Kal\u00e9n A, Magnusson P (2008) Acidic preparations of platelet concentrates release bone morphogenetic protein-2. Acta Orthop 79(3):433\u2013437","journal-title":"Acta Orthop"},{"key":"31_CR54","doi-asserted-by":"crossref","unstructured":"Kal\u00e9n A, Wahlstr\u00f6m O, Linder CH, Magnusson P (2008) The content of bone morphogenetic proteins in platelets varies greatly between different platelet donors. Biochem Biophys Res Commun 375(2):261\u2013264","DOI":"10.1016\/j.bbrc.2008.08.014"}],"container-title":["Journal of Orthopaedics and Traumatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10195-008-0031-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10195-008-0031-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10195-008-0031-5","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10195-008-0031-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,20]],"date-time":"2023-05-20T17:48:35Z","timestamp":1684604915000},"score":1,"resource":{"primary":{"URL":"https:\/\/jorthoptraumatol.springeropen.com\/articles\/10.1007\/s10195-008-0031-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,10,25]]},"references-count":54,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2008,12]]}},"alternative-id":["31"],"URL":"https:\/\/doi.org\/10.1007\/s10195-008-0031-5","relation":{},"ISSN":["1590-9921","1590-9999"],"issn-type":[{"value":"1590-9921","type":"print"},{"value":"1590-9999","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,10,25]]},"assertion":[{"value":"10 July 2008","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 September 2008","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 October 2008","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}