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Sweden has LTBI-screening policies for migrants that have not been previously evaluated. This study aimed to assess the cost-effectiveness of the current screening strategy in Stockholm.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A Markov model was developed to predict the costs and effects of the current LTBI-screening program compared to a scenario of no LTBI screening over a 50-year time horizon. Epidemiological and cost data were obtained from local sources when available. The primary outcomes were incremental cost-effectiveness ratio (ICER) in terms of societal cost per quality-adjusted life year (QALY).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Screening migrants in the age group 13\u201319\u00a0years had the lowest ICER, 300,082 Swedish Kronor (SEK)\/QALY, which is considered cost-effective in Sweden. In the age group 20\u201334, ICER was 714,527 SEK\/QALY (moderately cost-effectives) and in all age groups above 34 ICERs were above 1,000,000 SEK\/QALY (not cost-effective). ICER decreased with increasing TB incidence in country of origin.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Screening is cost-effective for young cohorts, mainly between 13 and 19, while cost-effectiveness in age group 20\u201334\u00a0years could be enhanced by focusing on migrants from highest incidence countries and\/or by increasing the LTBI treatment initiation rate. Screening is not cost-effective in older cohorts regardless of the country of origin.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s10198-021-01265-5","type":"journal-article","created":{"date-parts":[[2021,2,10]],"date-time":"2021-02-10T03:24:35Z","timestamp":1612927475000},"page":"445-454","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Cost-effectiveness of the latent tuberculosis screening program for migrants in Stockholm Region"],"prefix":"10.1007","volume":"22","author":[{"given":"Jad","family":"Shedrawy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte","family":"Deogan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanna Nederby","family":"\u00d6hd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria-Pia","family":"Hergens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith","family":"Bruchfeld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerker","family":"Jonsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Siroka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Knut","family":"L\u00f6nnroth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,2,9]]},"reference":[{"key":"1265_CR1","volume-title":"Global tuberculosis report 2019","author":"World Health Organisation","year":"2019","unstructured":"World Health Organisation: Global tuberculosis report 2019. 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