{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T10:54:11Z","timestamp":1789469651109,"version":"build-2803163510"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2024,2,25]],"date-time":"2024-02-25T00:00:00Z","timestamp":1708819200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,2,25]],"date-time":"2024-02-25T00:00:00Z","timestamp":1708819200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100009324","name":"Tommy's","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009324","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eur J Health Econ"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Policymakers use clinical and cost-effectiveness evidence to support decisions about health service commissioning. In England, the National Institute for Health and Care Excellence (NICE) recommend that in cost-effectiveness analyses \u201ceffectiveness\u201d is measured as quality-adjusted life years (QALYs), derived from health utility values. The impact of perinatal death (stillbirth\/neonatal death) on parents\u2019 health utility is currently unknown. This knowledge would improve the robustness of cost-effectiveness evidence for policymakers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to estimate the impact of perinatal death on parents\u2019 health utility.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>An online survey conducted with mothers and fathers in England who experienced a perinatal death. Participants reported how long ago their baby died and whether they\/their partner subsequently became pregnant again. They were asked to rate their health on the EQ-5D-5L instrument (generic health measure). EQ-5D-5L responses were used to calculate health utility values. These were compared with age-matched values for the general population to estimate a utility shortfall (i.e. health loss) associated with perinatal death.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There were 256 survey respondents with a median age of 40\u00a0years (IQR 26\u201340). Median time since death was 27\u00a0months (IQR 8\u201371). The mean utility value of the sample was 0.774 (95% CI 0.752\u20130.796). Utility values in the sample were 13% lower than general population values (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). Over 10\u00a0years, this equated to a loss of 1.1 QALYs. This reduction in health utility was driven by anxiety and depression.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Perinatal death has important and long-lasting health impacts on parents. Mental health support following perinatal bereavement is especially important.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s10198-024-01677-z","type":"journal-article","created":{"date-parts":[[2024,2,25]],"date-time":"2024-02-25T15:01:57Z","timestamp":1708873317000},"page":"1383-1391","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Measuring EQ-5D-5L utility values in parents who have experienced perinatal death"],"prefix":"10.1007","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9574-7710","authenticated-orcid":false,"given":"Elizabeth M.","family":"Camacho","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine J.","family":"Gold","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9979-9462","authenticated-orcid":false,"given":"Margaret","family":"Murphy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Storey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4303-7845","authenticated-orcid":false,"given":"Alexander E. 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