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The interventions included: (1) anticipatory guidance provided by oral health therapists via 1a) home visits or 1b) telehealth consultations; (2) school-based dental screening and fluoride varnish program delivered by 2a) dental practitioners or 2b) non-dental health professionals (no screening); and (3) school-based fissure sealant program. The base-case scenario included intervention and dental treatment costs, with six-year (1a and 1b) and two-year (2a, 2b and 3) time horizons. Sensitivity analysis included other healthcare costs (e.g. pulp therapy, extractions, etc.). Additionally, extrapolation modelling extended the 12-year time horizon (all interventions). Probability for cost-effectiveness applied AUD$50,000 per disability-adjusted life year (DALY) averted, and AUD$28,033 per quality-adjusted life year (QALY) gained willingness-to-pay thresholds. Under the base-case scenario, none of the interventions were cost-effective. Cost-effectiveness results were sensitive when including other healthcare costs and the 12-year time horizon. Probability for cost-effectiveness (DALYs averted\/QALYs gained) with extrapolation modelling in order of ranking were: (1) 91.5%\/94.7% for fluoride varnish, (2) 43.9%\/48.6% for dental screening and fluoride varnish, (3) 28.7%\/29.8% for anticipatory guidance via telehealth, (4) 17.1%\/20.0% for fissure sealant, and (5) 2.2%\/2.2% for anticipatory guidance via home visits.<\/jats:p>","DOI":"10.1007\/s10198-025-01787-2","type":"journal-article","created":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T23:19:22Z","timestamp":1745968762000},"page":"1525-1537","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Economic evaluation on dental caries preventive interventions for Australian children using a priority-setting approach"],"prefix":"10.1007","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9986-7629","authenticated-orcid":false,"given":"Tan Minh","family":"Nguyen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9442-6824","authenticated-orcid":false,"given":"Long Khanh-Dao","family":"Le","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1613-0585","authenticated-orcid":false,"given":"Hanny","family":"Calache","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7127-9462","authenticated-orcid":false,"given":"Cathrine","family":"Mihalopoulos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,4,30]]},"reference":[{"key":"1787_CR1","doi-asserted-by":"publisher","unstructured":"Ahovuo-Saloranta, A., Forss, H., Walsh, T., Nordblad, A., M\u00e4kel\u00e4, M., Worthington, H.V.: Pit and fissure sealants for preventing dental decay in permanent teeth. 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