{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T00:04:45Z","timestamp":1789603485085,"version":"build-2803163510"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2015,8,23]],"date-time":"2015-08-23T00:00:00Z","timestamp":1440288000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2015,8,23]],"date-time":"2015-08-23T00:00:00Z","timestamp":1440288000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["HL108272"],"award-info":[{"award-number":["HL108272"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["1354541"],"award-info":[{"award-number":["1354541"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Biomech Model Mechanobiol"],"published-print":{"date-parts":[[2016,6]]},"DOI":"10.1007\/s10237-015-0719-4","type":"journal-article","created":{"date-parts":[[2015,8,22]],"date-time":"2015-08-22T09:57:03Z","timestamp":1440237423000},"page":"713-722","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["A reduced-dimensional model for near-wall transport in cardiovascular flows"],"prefix":"10.1007","volume":"15","author":[{"given":"Kirk B.","family":"Hansen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shawn C.","family":"Shadden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,8,23]]},"reference":[{"issue":"12","key":"719_CR1","doi-asserted-by":"publisher","first-page":"H1786","DOI":"10.1152\/ajpheart.00461.2014","volume":"307","author":"A Arzani","year":"2014","unstructured":"Arzani A, Suh GY, Dalman RL, Shadden SC (2014) A longitudinal comparison of hemodynamics and intraluminal thrombus deposition in abdominal aortic aneurysms. Am J Physiol Heart Circ Physiol 307(12):H1786\u2013H1795","journal-title":"Am J Physiol Heart Circ Physiol"},{"issue":"6\u20138","key":"719_CR2","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1002\/fld.1484","volume":"54","author":"Y Bazilevs","year":"2007","unstructured":"Bazilevs Y, Calo VM, Tezduyar TE, Hughes TJR (2007) YZ$$\\beta $$ discontinuity capturing for advection-dominated processes with application to arterial drug delivery. Int J Numer Methods Fluids 54(6\u20138):593\u2013608","journal-title":"Int J Numer Methods Fluids"},{"issue":"2","key":"719_CR3","doi-asserted-by":"publisher","first-page":"380","DOI":"10.1007\/s10439-009-9843-6","volume":"38","author":"J Biasetti","year":"2009","unstructured":"Biasetti J, Gasser TC, Auer M, Hedin U, Labruto F (2009) Hemodynamics of the normal aorta compared to fusiform and saccular abdominal aortic aneurysms with emphasis on a potential thrombus formation mechanism. Ann Biomed Eng 38(2):380\u2013390","journal-title":"Ann Biomed Eng"},{"key":"719_CR4","doi-asserted-by":"publisher","first-page":"266","DOI":"10.3389\/fphys.2012.00266","volume":"3","author":"J Biasetti","year":"2012","unstructured":"Biasetti J, Spazzini PG, Swedenborg J, Gasser TC (2012) An integrated fluid-chemical model toward modeling the formation of intra-luminal thrombus in abdominal aortic aneurysms. Front Phys 3:266","journal-title":"Front Phys"},{"issue":"10","key":"719_CR5","doi-asserted-by":"publisher","first-page":"1038","DOI":"10.1002\/cnm.2581","volume":"29","author":"E Boileau","year":"2013","unstructured":"Boileau E, Bevan R, Sazonov I, Rees M, Nithiarasu P (2013) Flow-induced ATP release in patient-specific arterial geometries\u2014a comparative study of computational models. Int J Numer Methods Biomed Eng 29(10):1038\u20131056","journal-title":"Int J Numer Methods Biomed Eng"},{"issue":"1\u20133","key":"719_CR6","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/0045-7825(82)90071-8","volume":"32","author":"AN Brooks","year":"1982","unstructured":"Brooks AN, Hughes TJ (1982) Streamline upwind\/Petrov\u2013Galerkin formulations for convection dominated flows with particular emphasis on the incompressible Navier\u2013Stokes equations. Comput Methods Appl Mech Eng 32(1\u20133):199\u2013259","journal-title":"Comput Methods Appl Mech Eng"},{"issue":"3","key":"719_CR7","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1161\/01.RES.58.3.319","volume":"58","author":"G Burnstock","year":"1986","unstructured":"Burnstock G, Kennedy C (1986) A dual function for adenosine 5\u2019-triphosphate in the regulation of vascular tone: Excitatory cotransmitter with noradrenaline from perivascular nerves and locally released inhibitory intravascular agent. Circ Res 58(3):319\u2013330","journal-title":"Circ Res"},{"issue":"1","key":"719_CR8","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1067\/mva.2002.107","volume":"37","author":"CP Cheng","year":"2003","unstructured":"Cheng CP, Herfkens RJ, Taylor CA (2003) Comparison of abdominal aortic hemodynamics between men and women at rest and during lower limb exercise. J Vasc Surg 37(1):118\u2013123","journal-title":"J Vasc Surg"},{"issue":"10","key":"719_CR9","doi-asserted-by":"publisher","first-page":"1231","DOI":"10.1114\/1.1615574","volume":"31","author":"T David","year":"2003","unstructured":"David T (2003) Wall shear stress modulation of ATP\/ADP concentration at the endothelium. Ann Biomed Eng 31(10):1231\u20131237","journal-title":"Ann Biomed Eng"},{"issue":"4","key":"719_CR10","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1114\/1.1468890","volume":"30","author":"CR Ethier","year":"2002","unstructured":"Ethier CR (2002) Computational modeling of mass transfer and links to atherosclerosis. Ann Biomed Eng 30(4):461\u2013471","journal-title":"Ann Biomed Eng"},{"issue":"1","key":"719_CR11","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/j.jbiomech.2010.08.025","volume":"44","author":"S Fazli","year":"2011","unstructured":"Fazli S, Shirani E, Sadeghi M (2011) Numerical simulation of LDL mass transfer in a common carotid artery under pulsatile flows. J Biomech 44(1):68\u201376","journal-title":"J Biomech"},{"issue":"6","key":"719_CR12","doi-asserted-by":"publisher","first-page":"1121","DOI":"10.1016\/S0006-3495(89)82760-2","volume":"56","author":"BJ Folie","year":"1989","unstructured":"Folie BJ, McIntire LV (1989) Mathematical analysis of mural thrombogenesis. Concentration profiles of platelet-activating agents and effects of viscous shear flow. Biophys J 56(6):1121\u20131141","journal-title":"Biophys J"},{"key":"719_CR13","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4757-2696-1","volume-title":"Biomechanics","author":"YC Fung","year":"1997","unstructured":"Fung YC (1997) Biomechanics. Springer, New York"},{"issue":"11","key":"719_CR14","doi-asserted-by":"publisher","first-page":"1309","DOI":"10.1002\/nme.2579","volume":"79","author":"C Geuzaine","year":"2009","unstructured":"Geuzaine C, Remacle JF (2009) Gmsh: A 3-D finite element mesh generator with built-in pre- and post-processing facilities. Int J Numer Methods Eng 79(11):1309\u20131331","journal-title":"Int J Numer Methods Eng"},{"issue":"6","key":"719_CR15","doi-asserted-by":"publisher","first-page":"745","DOI":"10.1016\/0017-9310(78)90036-4","volume":"21","author":"R Ghez","year":"1978","unstructured":"Ghez R (1978) Mass transport and surface reactions in L\u00e9v\u00eaque\u2019s approximation. Int J Heat Mass Transp 21(6):745\u2013750","journal-title":"Int J Heat Mass Transp"},{"issue":"3","key":"719_CR16","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1055\/s-0038-1661576","volume":"55","author":"HL Goldsmith","year":"1986","unstructured":"Goldsmith HL, Turrito VT (1986) Rheological aspects of thrombosis and haemostasis: basic principles and applications. ICTH-Report-Subcommittee on Rheology of the International Committee on Thrombosis and Haemostasis. Thromb Haemost 55(3):415\u2013435","journal-title":"Thromb Haemost"},{"issue":"8","key":"719_CR17","doi-asserted-by":"publisher","first-page":"1729","DOI":"10.1161\/01.ATV.0000229658.76797.30","volume":"26","author":"JJ Hathcock","year":"2006","unstructured":"Hathcock JJ (2006) Flow effects on coagulation and thrombosis. Arter Thromb Vasc Biol 26(8):1729\u20131737","journal-title":"Arter Thromb Vasc Biol"},{"issue":"3","key":"719_CR18","doi-asserted-by":"publisher","first-page":"031,903","DOI":"10.1063\/1.4913754","volume":"27","author":"F Iori","year":"2015","unstructured":"Iori F, Grechy L, Corbett RW, Gedroyc W, Duncan N, Caro CG, Vincent PE (2015) The effect of in-plane arterial curvature on blood flow and oxygen transport in arterio-venous fistulae. Phys Fluids 27(3):031,903","journal-title":"Phys Fluids"},{"issue":"9","key":"719_CR19","doi-asserted-by":"publisher","first-page":"740","DOI":"10.1114\/1.1397792","volume":"29","author":"K John","year":"2001","unstructured":"John K, Barakat AI (2001) Modulation of ATP\/ADP concentration at the endothelial surface by shear stress: effect of flow-induced ATP release. Ann Biomed Eng 29(9):740\u2013751","journal-title":"Ann Biomed Eng"},{"issue":"21\u201322","key":"719_CR20","doi-asserted-by":"publisher","first-page":"4510","DOI":"10.1016\/j.ijheatmasstransfer.2005.05.004","volume":"48","author":"M Kaazempur-Mofrad","year":"2005","unstructured":"Kaazempur-Mofrad M, Wada S, Myers J, Ethier C (2005) Mass transport and fluid flow in stenotic arteries: axisymmetric and asymmetric models. Int J Heat Mass Transp 48(21\u201322):4510\u20134517","journal-title":"Int J Heat Mass Transp"},{"issue":"4","key":"719_CR21","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1002\/zamm.19210010401","volume":"1","author":"T von K\u00e1rm\u00e1n","year":"1921","unstructured":"von K\u00e1rm\u00e1n T (1921) \u00dcber laminare und turbulente Reibung. Z Angew Math Mech 1(4):233\u2013252","journal-title":"Z Angew Math Mech"},{"issue":"12","key":"719_CR22","doi-asserted-by":"publisher","first-page":"1820","DOI":"10.1007\/s10439-006-9188-3","volume":"34","author":"MK Kolandavel","year":"2006","unstructured":"Kolandavel MK, Fruend ET, Ringgaard S, Walker PG (2006) The effects of time varying curvature on species transport in coronary arteries. Ann Biomed Eng 34(12):1820\u20131832","journal-title":"Ann Biomed Eng"},{"issue":"3","key":"719_CR23","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1016\/j.jbiomech.2011.11.039","volume":"45","author":"J Lantz","year":"2012","unstructured":"Lantz J, Karlsson M (2012) Large eddy simulation of LDL surface concentration in a subject specific human aorta. J Biomech 45(3):537\u2013542","journal-title":"J Biomech"},{"issue":"1","key":"719_CR24","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1093\/imammb\/dqq005","volume":"28","author":"K Leiderman","year":"2010","unstructured":"Leiderman K, Fogelson AL (2010) Grow with the flow: a spatial-temporal model of platelet deposition and blood coagulation under flow. Math Med Biol 28(1):47\u201384","journal-title":"Math Med Biol"},{"key":"719_CR25","first-page":"201","volume":"13","author":"M L\u00e9v\u00eaque","year":"1928","unstructured":"L\u00e9v\u00eaque M (1928) Les lois de la transmission de chaleur par convection. Ann Mines 13:201\u2013239","journal-title":"Ann Mines"},{"key":"719_CR26","doi-asserted-by":"crossref","unstructured":"Logg A, Mardal KA, Wells G (eds) (2012) Automated solution of differential equations by the finite element method, Lecture Notes in Computational Science and Engineering, vol 84. Springer, Berlin, Heidelberg","DOI":"10.1007\/978-3-642-23099-8"},{"issue":"17","key":"719_CR27","doi-asserted-by":"publisher","first-page":"2723","DOI":"10.1016\/0017-9310(94)90389-1","volume":"37","author":"P Ma","year":"1994","unstructured":"Ma P, Li X, Ku DN (1994) Heat and mass transfer in a separated flow region for high Prandtl and Schmidt numbers under pulsatile conditions. Int J Heat Mass Transp 37(17):2723\u20132736","journal-title":"Int J Heat Mass Transp"},{"issue":"2","key":"719_CR28","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1016\/j.medengphy.2013.10.012","volume":"36","author":"KP Papadopoulos","year":"2014","unstructured":"Papadopoulos KP, Gavaises M, Atkin C (2014) A simplified mathematical model for thrombin generation. Med Eng Phys 36(2):196\u2013204","journal-title":"Med Eng Phys"},{"key":"719_CR29","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1093\/cvr\/cvt044","volume":"99","author":"V Peiffer","year":"2013","unstructured":"Peiffer V, Sherwin SJ, Weinberg PD (2013) Does low and oscillatory wall shear stress correlate spatially with early atherosclerosis? a systematic review. Cardiovasc Res 99:242\u2013250","journal-title":"Cardiovasc Res"},{"issue":"2066","key":"719_CR30","doi-asserted-by":"publisher","first-page":"671","DOI":"10.1098\/rspa.2005.1591","volume":"462","author":"M Plank","year":"2006","unstructured":"Plank M, Comerford A, David T, Wall D (2006) Concentration of blood-borne agonists at the endothelium. Proc R Soc A Math Phys Eng Sci 462(2066):671\u2013688","journal-title":"Proc R Soc A Math Phys Eng Sci"},{"issue":"6","key":"719_CR31","doi-asserted-by":"publisher","first-page":"2099","DOI":"10.5194\/gmd-6-2099-2013","volume":"6","author":"ME Rognes","year":"2013","unstructured":"Rognes ME, Ham DA, Cotter CJ, McRae ATT (2013) Automating the solution of PDEs on the sphere and other manifolds in FEniCS 1.2. Geosci Model Dev 6(6):2099\u20132119","journal-title":"Geosci Model Dev"},{"issue":"4","key":"719_CR32","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1114\/1.200","volume":"27","author":"EN Sorensen","year":"1999","unstructured":"Sorensen EN, Burgreen GW, Wagner WR, Antaki JF (1999) Computational simulation of platelet deposition and activation: I. Model development and properties. Ann Biomed Eng 27(4):436\u2013448","journal-title":"Ann Biomed Eng"},{"key":"719_CR33","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1017\/S0022112006001200","volume":"564","author":"A Surana","year":"2006","unstructured":"Surana A, Grunberg O, Haller G (2006) Exact theory of three-dimensional flow separation. Part 1. Steady separation. J Fluid Mech 564:57\u2013103","journal-title":"J Fluid Mech"},{"issue":"1","key":"719_CR34","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1146\/annurev.bioeng.5.040202.121529","volume":"5","author":"JM Tarbell","year":"2003","unstructured":"Tarbell JM (2003) Mass transport in arteries and the localization of atherosclerosis. Annu Rev Biomed Eng 5(1):79\u2013118","journal-title":"Annu Rev Biomed Eng"},{"key":"719_CR35","volume-title":"Transport phenomena in biological systems","author":"GA Truskey","year":"2004","unstructured":"Truskey GA, Yuan F, Katz DF (2004) Transport phenomena in biological systems. Pearson\/Prentice Hall, Upper Saddle River"},{"issue":"6","key":"719_CR36","doi-asserted-by":"publisher","first-page":"1331","DOI":"10.1111\/j.1538-7836.2006.01967.x","volume":"4","author":"R Wagenvoord","year":"2006","unstructured":"Wagenvoord R, Hemker PW, Hemker HC (2006) The limits of simulation of the clotting system. J Thromb Haemost 4(6):1331\u20131338","journal-title":"J Thromb Haemost"}],"container-title":["Biomechanics and Modeling in Mechanobiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10237-015-0719-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10237-015-0719-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10237-015-0719-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10237-015-0719-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,16]],"date-time":"2020-05-16T16:51:35Z","timestamp":1589647895000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10237-015-0719-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,8,23]]},"references-count":36,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,6]]}},"alternative-id":["719"],"URL":"https:\/\/doi.org\/10.1007\/s10237-015-0719-4","relation":{},"ISSN":["1617-7959","1617-7940"],"issn-type":[{"value":"1617-7959","type":"print"},{"value":"1617-7940","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,8,23]]},"assertion":[{"value":"12 May 2015","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 August 2015","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 August 2015","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}