{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T04:38:22Z","timestamp":1785731902341,"version":"3.56.0"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2017,6,5]],"date-time":"2017-06-05T00:00:00Z","timestamp":1496620800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100004963","name":"Seventh Framework Programme","doi-asserted-by":"publisher","award":["Grant Agreement n. 600376"],"award-info":[{"award-number":["Grant Agreement n. 600376"]}],"id":[{"id":"10.13039\/501100004963","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Biomech Model Mechanobiol"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1007\/s10237-017-0922-6","type":"journal-article","created":{"date-parts":[[2017,6,5]],"date-time":"2017-06-05T07:15:00Z","timestamp":1496646900000},"page":"1833-1843","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["From single muscle fiber to whole muscle mechanics: a finite element model of a muscle bundle with fast and slow fibers"],"prefix":"10.1007","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9542-4417","authenticated-orcid":false,"given":"Lorenzo","family":"Marcucci","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Reggiani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arturo N.","family":"Natali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piero G.","family":"Pavan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,6,5]]},"reference":[{"key":"922_CR1","doi-asserted-by":"publisher","first-page":"1072","DOI":"10.1093\/icb\/icu070","volume":"54","author":"AA Biewener","year":"2014","unstructured":"Biewener AA, Wakeling JM, Lee SS, Arnold AS (2014) Validation of hill-type muscle models in relation to neuromuscular recruitment and force\u2013velocity properties: predicting patterns of in vivo muscle force. Integr Comp Biol 54:1072\u20131083. doi: 10.1093\/icb\/icu070","journal-title":"Integr Comp Biol"},{"key":"922_CR2","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1113\/jphysiol.1996.sp021617","volume":"495","author":"R Bottinelli","year":"1996","unstructured":"Bottinelli R, Canepari M, Pellegrino MA, Reggiani C (1996) Force\u2013velocity properties of human skeletal muscle fibres: myosin heavy chain isoform and temperature dependence. J Physiol 495:573","journal-title":"J Physiol"},{"key":"922_CR3","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1016\/S0079-6107(00)00006-7","volume":"73","author":"R Bottinelli","year":"2000","unstructured":"Bottinelli R, Reggiani C (2000) Human skeletal muscle fibres: molecular and functional diversity. Prog Biophys Mol Biol 73:195\u2013262. doi: 10.1016\/S0079-6107(00)00006-7","journal-title":"Prog Biophys Mol Biol"},{"key":"922_CR4","doi-asserted-by":"publisher","first-page":"1013","DOI":"10.1038\/nmeth.2152","volume":"9","author":"M Capitanio","year":"2012","unstructured":"Capitanio M, Canepari M, Maffei M et al (2012) Ultrafast force-clamp spectroscopy of single molecules reveals load dependence of myosin working stroke. Nat Methods 9:1013\u20131019. doi: 10.1038\/nmeth.2152","journal-title":"Nat Methods"},{"key":"922_CR5","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1113\/jphysiol.1972.sp010016","volume":"227","author":"DR Cleworth","year":"1972","unstructured":"Cleworth DR, Edman KaP (1972) Changes in sarcomere length during isometric tension development in frog skeletal muscle. J Physiol 227:1\u201317. doi: 10.1113\/jphysiol.1972.sp010016","journal-title":"J Physiol"},{"key":"922_CR6","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1113\/jphysiol.1979.sp012804","volume":"291","author":"KA Edman","year":"1979","unstructured":"Edman KA (1979) The velocity of unloaded shortening and its relation to sarcomere length and isometric force in vertebrate muscle fibres. J Physiol 291:143\u2013159","journal-title":"J Physiol"},{"key":"922_CR7","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1016\/j.jmps.2010.12.008","volume":"59","author":"AE Ehret","year":"2011","unstructured":"Ehret AE, B\u00f6l M, Itskov M (2011) A continuum constitutive model for the active behaviour of skeletal muscle. J Mech Phys Solids 59:625\u2013636. doi: 10.1016\/j.jmps.2010.12.008","journal-title":"J Mech Phys Solids"},{"key":"922_CR8","doi-asserted-by":"publisher","first-page":"13591","DOI":"10.1074\/jbc.R200021200","volume":"278","author":"JM Ervasti","year":"2003","unstructured":"Ervasti JM (2003) Costameres: the Achilles\u2019 Heel of Herculean muscle. J Biol Chem 278:13591\u201313594. doi: 10.1074\/jbc.R200021200","journal-title":"J Biol Chem"},{"key":"922_CR9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2016.08.030","author":"A Hamouda","year":"2016","unstructured":"Hamouda A, Kenney L, Howard D (2016) Dealing with time-varying recruitment and length in Hill-type muscle models. J Biomech. doi: 10.1016\/j.jbiomech.2016.08.030","journal-title":"J Biomech"},{"key":"922_CR10","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00542.2015","author":"H Hauraix","year":"2015","unstructured":"Hauraix H, Nordez A, Guilhem G et al (2015) In vivo maximal fascicle-shortening velocity during plantar flexion in human. J Appl Physiol. doi: 10.1152\/japplphysiol.00542.2015","journal-title":"J Appl Physiol"},{"key":"922_CR11","doi-asserted-by":"publisher","first-page":"945","DOI":"10.1016\/S0006-3495(00)76349-1","volume":"79","author":"ZH He","year":"2000","unstructured":"He ZH, Bottinelli R, Pellegrino MA et al (2000) ATP consumption and efficiency of human single muscle fibers with different myosin isoform composition. Biophys J 79:945. doi: 10.1016\/S0006-3495(00)76349-1","journal-title":"Biophys J"},{"key":"922_CR12","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1098\/rspb.1938.0050","volume":"126","author":"AV Hill","year":"1938","unstructured":"Hill AV (1938) The heat of shortening and the dynamic constants of muscle. Proc R Soc Lond B Biol Sci 126:136\u2013195. doi: 10.1098\/rspb.1938.0050","journal-title":"Proc R Soc Lond B Biol Sci"},{"key":"922_CR13","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.2014.0002","author":"NC Holt","year":"2014","unstructured":"Holt NC, Wakeling JM, Biewener AA (2014) The effect of fast and slow motor unit activation on whole-muscle mechanical performance: the size principle may not pose a mechanical paradox. Proc R Soc B Biol Sci. doi: 10.1098\/rspb.2014.0002","journal-title":"Proc R Soc B Biol Sci"},{"key":"922_CR14","doi-asserted-by":"publisher","first-page":"1126","DOI":"10.1164\/rccm.201412-2214OC","volume":"191","author":"PE Hooijman","year":"2015","unstructured":"Hooijman PE, Beishuizen A, Witt CC et al (2015) Diaphragm muscle fiber weakness and ubiquitin\u2013proteasome activation in critically Ill patients. Am J Respir Crit Care Med 191:1126\u20131138. doi: 10.1164\/rccm.201412-2214OC","journal-title":"Am J Respir Crit Care Med"},{"key":"922_CR15","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1006\/jtbi.2000.2109","volume":"206","author":"T Johansson","year":"2000","unstructured":"Johansson T, Meier P, Blickhan R (2000) A finite-element model for the mechanical analysis of skeletal muscles. J Theor Biol 206:131\u2013149. doi: 10.1006\/jtbi.2000.2109","journal-title":"J Theor Biol"},{"key":"922_CR16","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1111\/j.1748-1716.1988.tb08338.x","volume":"132","author":"RK Josephson","year":"1988","unstructured":"Josephson RK, Edman KAP (1988) The consequences of fibre heterogeneity on the force-velocity relation of skeletal muscle. Acta Physiol Scand 132:341\u2013352. doi: 10.1111\/j.1748-1716.1988.tb08338.x","journal-title":"Acta Physiol Scand"},{"key":"922_CR17","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1038\/16403","volume":"397","author":"K Kitamura","year":"1999","unstructured":"Kitamura K, Tokunaga M, Iwane AH, Yanagida T (1999) A single myosin head moves along an actin filament with regular steps of 5.3 nanometres. Nature 397:129\u2013134. doi: 10.1038\/16403","journal-title":"Nature"},{"key":"922_CR18","doi-asserted-by":"publisher","first-page":"941","DOI":"10.1002\/(SICI)1097-0207(19981115)43:5<d941::AID-NME435>3.0.CO;2-3","volume":"43","author":"M Kojic","year":"1998","unstructured":"Kojic M, Mijailovic S, Zdravkovic N (1998) Modelling of muscle behaviour by the finite element method using Hill\u2019s three-element model. Int J Numer Methods Eng 43:941\u2013953. doi: 10.1002\/(SICI)1097-0207(19981115)43:5<d941::AID-NME435>3.0.CO;2-3","journal-title":"Int J Numer Methods Eng"},{"key":"922_CR19","doi-asserted-by":"publisher","first-page":"2288","DOI":"10.1016\/j.jbiomech.2013.06.001","volume":"46","author":"SSM Lee","year":"2013","unstructured":"Lee SSM, Arnold AS, Miara M de B et al (2013) Accuracy of gastrocnemius muscles forces in walking and running goats predicted by one-element and two-element Hill-type models. J Biomech 46:2288\u20132295. doi: 10.1016\/j.jbiomech.2013.06.001","journal-title":"J Biomech"},{"key":"922_CR20","doi-asserted-by":"publisher","first-page":"1235","DOI":"10.1152\/japplphysiol.01121.2012","volume":"114","author":"S Levine","year":"2013","unstructured":"Levine S, Bashir MH, Clanton TL et al (2013) COPD elicits remodeling of the diaphragm and vastus lateralis muscles in humans. J Appl Physiol 114:1235\u20131245. doi: 10.1152\/japplphysiol.01121.2012","journal-title":"J Appl Physiol"},{"key":"922_CR21","doi-asserted-by":"publisher","first-page":"1466","DOI":"10.1098\/rstb.2010.0316","volume":"366","author":"RL Lieber","year":"2011","unstructured":"Lieber RL, Ward SR (2011) Skeletal muscle design to meet functional demands. Philos Trans R Soc B Biol Sci 366:1466. doi: 10.1098\/rstb.2010.0316","journal-title":"Philos Trans R Soc B Biol Sci"},{"key":"922_CR22","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1242\/jeb.126.1.63","volume":"126","author":"RL Marsh","year":"1986","unstructured":"Marsh RL, Bennett AF (1986) Thermal dependence of contractile properties of skeletal muscle from the lizard Sceloporus occidentalis with comments on methods for fitting and comparing force\u2013velocity curves. J Exp Biol 126:63","journal-title":"J Exp Biol"},{"key":"922_CR23","doi-asserted-by":"publisher","first-page":"1109","DOI":"10.1016\/j.neuron.2015.11.022","volume":"88","author":"GN Sanchez","year":"2015","unstructured":"Sanchez GN, Sinha S, Liske H et al (2015) In vivo imaging of human sarcomere twitch dynamics in individual motor units. Neuron 88:1109\u20131120. doi: 10.1016\/j.neuron.2015.11.022","journal-title":"Neuron"},{"key":"922_CR24","doi-asserted-by":"publisher","first-page":"3207","DOI":"10.1016\/j.jbiomech.2010.07.020","volume":"43","author":"B Sharafi","year":"2010","unstructured":"Sharafi B, Blemker SS (2010) A micromechanical model of skeletal muscle to explore the effects of fiber and fascicle geometry. J Biomech 43:3207\u20133213. doi: 10.1016\/j.jbiomech.2010.07.020","journal-title":"J Biomech"},{"key":"922_CR25","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1038\/372515a0","volume":"372","author":"JA Spudich","year":"1994","unstructured":"Spudich JA (1994) How molecular motors work. Nature 372:515\u2013518. doi: 10.1038\/372515a0","journal-title":"Nature"},{"key":"922_CR26","doi-asserted-by":"publisher","first-page":"865","DOI":"10.1016\/j.jbiomech.2009.01.021","volume":"42","author":"CY Tang","year":"2009","unstructured":"Tang CY, Zhang G, Tsui CP (2009) A 3D skeletal muscle model coupled with active contraction of muscle fibres and hyperelastic behaviour. J Biomech 42:865\u2013872. doi: 10.1016\/j.jbiomech.2009.01.021","journal-title":"J Biomech"},{"key":"922_CR27","doi-asserted-by":"publisher","first-page":"20140080","DOI":"10.1098\/rsfs.2014.0080","volume":"5","author":"KM Virgilio","year":"2015","unstructured":"Virgilio KM, Martin KS, Peirce SM, Blemker SS (2015) Multiscale models of skeletal muscle reveal the complex effects of muscular dystrophy on tissue mechanics and damage susceptibility. Interface Focus 5:20140080. doi: 10.1098\/rsfs.2014.0080","journal-title":"Interface Focus"},{"key":"922_CR28","doi-asserted-by":"publisher","first-page":"1708","DOI":"10.1007\/s10439-012-0531-6","volume":"40","author":"JM Wakeling","year":"2012","unstructured":"Wakeling JM, Lee SSM, Arnold AS et al (2012) A muscle\u2019s force depends on the recruitment patterns of its fibers. Ann Biomed Eng 40:1708\u20131720. doi: 10.1007\/s10439-012-0531-6","journal-title":"Ann Biomed Eng"}],"container-title":["Biomechanics and Modeling in Mechanobiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10237-017-0922-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10237-017-0922-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10237-017-0922-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,29]],"date-time":"2022-07-29T04:20:04Z","timestamp":1659068404000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10237-017-0922-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,5]]},"references-count":28,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["922"],"URL":"https:\/\/doi.org\/10.1007\/s10237-017-0922-6","relation":{},"ISSN":["1617-7959","1617-7940"],"issn-type":[{"value":"1617-7959","type":"print"},{"value":"1617-7940","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,6,5]]}}}