{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T05:32:41Z","timestamp":1771565561936,"version":"3.50.1"},"reference-count":46,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2024,12,26]],"date-time":"2024-12-26T00:00:00Z","timestamp":1735171200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,12,26]],"date-time":"2024-12-26T00:00:00Z","timestamp":1735171200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100004204","name":"Tongji University","doi-asserted-by":"publisher","award":["1500219128"],"award-info":[{"award-number":["1500219128"]}],"id":[{"id":"10.13039\/501100004204","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Biomech Model Mechanobiol"],"published-print":{"date-parts":[[2025,4]]},"DOI":"10.1007\/s10237-024-01917-4","type":"journal-article","created":{"date-parts":[[2024,12,26]],"date-time":"2024-12-26T10:50:36Z","timestamp":1735210236000},"page":"441-454","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Region-specific biomechanical characterization of ascending thoracic aortic aneurysm of hypertensive patients with bicuspid aortic valves"],"prefix":"10.1007","volume":"24","author":[{"given":"Xiaojuan","family":"Xu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fan","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yue","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuan-Feng","family":"Xin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianhua","family":"Tong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,12,26]]},"reference":[{"key":"1917_CR1","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.jmbbm.2019.06.001","volume":"98","author":"DC Angouras","year":"2019","unstructured":"Angouras DC, Kritharis EP, Sokolis DP (2019) Regional distribution of delamination strength in ascending thoracic aortic aneurysms. J Mech Behav Biomed Mater 98:58\u201370. https:\/\/doi.org\/10.1016\/j.jmbbm.2019.06.001","journal-title":"J Mech Behav Biomed Mater"},{"key":"1917_CR2","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1016\/j.athoracsur.2013.03.094","volume":"96","author":"AN Azadani","year":"2013","unstructured":"Azadani AN et al (2013) Biomechanical properties of human ascending thoracic aortic aneurysms. Ann Thorac Surg 96:50\u201358. https:\/\/doi.org\/10.1016\/j.athoracsur.2013.03.094","journal-title":"Ann Thorac Surg"},{"key":"1917_CR3","doi-asserted-by":"publisher","first-page":"2112","DOI":"10.1016\/j.jtcvs.2018.05.095","volume":"156","author":"E Bollache","year":"2018","unstructured":"Bollache E et al (2018) Aortic valve-mediated wall shear stress is heterogeneous and predicts regional aortic elastic fiber thinning in bicuspid aortic valve-associated aortopathy. J Thorac Cardiovasc Surg 156:2112\u20132120. https:\/\/doi.org\/10.1016\/j.jtcvs.2018.05.095","journal-title":"J Thorac Cardiovasc Surg"},{"key":"1917_CR4","doi-asserted-by":"publisher","first-page":"864","DOI":"10.1161\/circresaha.121.318061","volume":"128","author":"P Boutouyrie","year":"2021","unstructured":"Boutouyrie P, Chowienczyk P, Humphrey JD, Mitchell GF (2021) Arterial stiffness and cardiovascular risk in hypertension. Circ Res 128:864\u2013886. https:\/\/doi.org\/10.1161\/circresaha.121.318061","journal-title":"Circ Res"},{"key":"1917_CR5","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1053\/ejvs.2002.1620","volume":"23","author":"M Carmo","year":"2002","unstructured":"Carmo M et al (2002) Alteration of elastin, collagen and their crosslinks in abdominal aortic aneurysms. Eur J Vasc Endovasc Surg 23:543\u2013549. https:\/\/doi.org\/10.1053\/ejvs.2002.1620","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"1917_CR6","doi-asserted-by":"publisher","DOI":"10.1161\/jaha.120.016715","volume":"9","author":"JC Chung","year":"2020","unstructured":"Chung JC et al (2020) Biomechanics of aortic dissection: a comparison of aortas associated with bicuspid and tricuspid aortic valves. J Am Heart Assoc 9:e016715. https:\/\/doi.org\/10.1161\/jaha.120.016715","journal-title":"J Am Heart Assoc"},{"key":"1917_CR7","doi-asserted-by":"publisher","first-page":"949","DOI":"10.1109\/tbme.2019.2924955","volume":"67","author":"F Condemi","year":"2020","unstructured":"Condemi F, Campisi S, Viallon M, Croisille P, Avril S (2020) Relationship between ascending thoracic aortic aneurysms hemodynamics and biomechanical properties. IEEE Trans Biomed Eng 67:949\u2013956. https:\/\/doi.org\/10.1109\/tbme.2019.2924955","journal-title":"IEEE Trans Biomed Eng"},{"key":"1917_CR8","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1016\/j.actbio.2023.08.016","volume":"169","author":"F Consentino","year":"2023","unstructured":"Consentino F et al (2023) Regional biomechanical characterization of human ascending aortic aneurysm: microstructure and biaxial mechanical response. Acta Biomater 169:107\u2013117. https:\/\/doi.org\/10.1016\/j.actbio.2023.08.016","journal-title":"Acta Biomater"},{"key":"1917_CR9","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/s0003-4975(01)03236-2","volume":"73","author":"RR Davies","year":"2002","unstructured":"Davies RR et al (2002) Yearly rupture or dissection rates for thoracic aortic aneurysms: simple prediction based on size. Ann Thorac Surg 73:17\u201327. https:\/\/doi.org\/10.1016\/s0003-4975(01)03236-2","journal-title":"Ann Thorac Surg"},{"key":"1917_CR10","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/j.medengphy.2020.07.003","volume":"82","author":"G De Nisco","year":"2020","unstructured":"De Nisco G et al (2020) Deciphering ascending thoracic aortic aneurysms hemodynamics in relation to biomechanical properties. Med Eng Phys 82:119\u2013129. https:\/\/doi.org\/10.1016\/j.medengphy.2020.07.003","journal-title":"Med Eng Phys"},{"key":"1917_CR11","doi-asserted-by":"publisher","first-page":"1692","DOI":"10.1016\/j.athoracsur.2018.05.071","volume":"106","author":"RP Deveja","year":"2018","unstructured":"Deveja RP et al (2018) Effect of aneurysm and bicuspid aortic valve on layer-specific ascending aorta mechanics. Ann Thorac Surg 106:1692\u20131701. https:\/\/doi.org\/10.1016\/j.athoracsur.2018.05.071","journal-title":"Ann Thorac Surg"},{"key":"1917_CR12","doi-asserted-by":"publisher","first-page":"700","DOI":"10.1016\/j.ejvs.2010.02.015","volume":"39","author":"A Duprey","year":"2010","unstructured":"Duprey A, Khanafe K, Schlicht M, Avril S, Williams D, Berguer R (2010) In vitro characterisation of physiological and maximum elastic modulus of ascending thoracic aortic aneurysms using uniaxial tensile testing. Eur J Vasc Endovasc Surg 39:700\u2013707. https:\/\/doi.org\/10.1016\/j.ejvs.2010.02.015","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"1917_CR13","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1016\/j.actbio.2016.06.028","volume":"42","author":"A Duprey","year":"2016","unstructured":"Duprey A, Trabelsi O, Vola M, Favre JP, Avril S (2016) Biaxial rupture properties of ascending thoracic aortic aneurysms. Acta Biomater 42:273\u2013285. https:\/\/doi.org\/10.1016\/j.actbio.2016.06.028","journal-title":"Acta Biomater"},{"key":"1917_CR14","doi-asserted-by":"publisher","DOI":"10.1136\/openhrt-2014-000169","volume":"2","author":"JA Elefteriades","year":"2015","unstructured":"Elefteriades JA, Sang A, Kuzmik G, Hornick M (2015) Guilt by association: paradigm for detecting a silent killer (thoracic aortic aneurysm). Open Heart 2:e000169. https:\/\/doi.org\/10.1136\/openhrt-2014-000169","journal-title":"Open Heart"},{"key":"1917_CR15","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jmbbm.2017.08.032","volume":"77","author":"A Ferrara","year":"2018","unstructured":"Ferrara A, Totaro P, Morganti S, Auricchio F (2018) Effects of clinico-pathological risk factors on in-vitro mechanical properties of human dilated ascending aorta. J Mech Behav Biomed Mater 77:1\u201311. https:\/\/doi.org\/10.1016\/j.jmbbm.2017.08.032","journal-title":"J Mech Behav Biomed Mater"},{"key":"1917_CR16","doi-asserted-by":"publisher","first-page":"807","DOI":"10.1016\/j.athoracsur.2019.12.035","volume":"110","author":"A Gomez","year":"2020","unstructured":"Gomez A et al (2020) Wall stress distribution in bicuspid aortic valve-associated ascending thoracic aortic aneurysms. Ann Thorac Surg 110:807\u2013814. https:\/\/doi.org\/10.1016\/j.athoracsur.2019.12.035","journal-title":"Ann Thorac Surg"},{"key":"1917_CR17","doi-asserted-by":"publisher","first-page":"892","DOI":"10.1016\/j.jacc.2015.06.1310","volume":"66","author":"DG Guzzardi","year":"2015","unstructured":"Guzzardi DG et al (2015) Valve-related hemodynamics mediate human bicuspid aortopathy: insights from wall shear stress mapping. J Am Coll Cardiol 66:892\u2013900. https:\/\/doi.org\/10.1016\/j.jacc.2015.06.1310","journal-title":"J Am Coll Cardiol"},{"key":"1917_CR18","volume-title":"Nonlinear solid mechanics: a continuum approach for engineering","author":"GA Holzapfel","year":"2000","unstructured":"Holzapfel GA (2000) Nonlinear solid mechanics: a continuum approach for engineering. John Wiley & Sons, Chichester, UK"},{"key":"1917_CR19","doi-asserted-by":"publisher","first-page":"H2048","DOI":"10.1152\/ajpheart.00934.2004","volume":"289","author":"GA Holzapfel","year":"2005","unstructured":"Holzapfel GA, Sommer G, Gasser TC, Regitnig P (2005) Determination of layer-specific mechanical properties of human coronary arteries with nonatherosclerotic intimal thickening and related constitutive modeling. Am J Physiol Heart Circ Physiol 289:H2048-2058. https:\/\/doi.org\/10.1152\/ajpheart.00934.2004","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"1917_CR20","doi-asserted-by":"publisher","first-page":"2031","DOI":"10.1161\/circulationaha.112.000483","volume":"127","author":"DP Howard","year":"2013","unstructured":"Howard DP et al (2013) Population-based study of incidence and outcome of acute aortic dissection and premorbid risk factor control: 10-year results from the Oxford Vascular Study. Circulation 127:2031\u20132037. https:\/\/doi.org\/10.1161\/circulationaha.112.000483","journal-title":"Circulation"},{"key":"1917_CR21","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/j.jtcvs.2008.07.023","volume":"137","author":"DC Iliopoulos","year":"2009","unstructured":"Iliopoulos DC, Kritharis EP, Giagini AT, Papadodima SA, Sokolis DP (2009) Ascending thoracic aortic aneurysms are associated with compositional remodeling and vessel stiffening but not weakening in age-matched subjects. J Thorac Cardiovasc Surg 137:101\u2013109. https:\/\/doi.org\/10.1016\/j.jtcvs.2008.07.023","journal-title":"J Thorac Cardiovasc Surg"},{"key":"1917_CR22","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2022.111133","volume":"138","author":"E Kefalidi","year":"2022","unstructured":"Kefalidi E, Angouras DC, Sokolis DP (2022) Regional and directional variations in the layer-specific resistance to tear propagation in ascending thoracic aortic aneurysms. J Biomech 138:111133. https:\/\/doi.org\/10.1016\/j.jbiomech.2022.111133","journal-title":"J Biomech"},{"key":"1917_CR23","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1016\/j.actbio.2022.06.019","volume":"149","author":"S Lin","year":"2022","unstructured":"Lin S, Morgant MC, Mar\u00edn-Castrill\u00f3n DM, Walker PM, Gl\u00e9l\u00e9 LSA, Boucher A, Presles B, Bouchot O, Lalande A (2022) Aortic local biomechanical properties in ascending aortic aneurysms. Acta Biomater 149:40\u201350. https:\/\/doi.org\/10.1016\/j.actbio.2022.06.019","journal-title":"Acta Biomater"},{"key":"1917_CR24","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1161\/circulationaha.113.003026","volume":"100","author":"R Mahadevia","year":"2014","unstructured":"Mahadevia R et al (2014) Bicuspid aortic cusp fusion morphology alters aortic three-dimensional outflow patterns, wall shear stress, and expression of aortopathy. Circulation 100:673\u2013682. https:\/\/doi.org\/10.1161\/circulationaha.113.003026","journal-title":"Circulation"},{"key":"1917_CR25","doi-asserted-by":"publisher","first-page":"9392","DOI":"10.1016\/j.actbio.2013.07.044","volume":"9","author":"C Martin","year":"2013","unstructured":"Martin C, Sun W, Pham T, Elefteriades J (2013) Predictive biomechanical analysis of ascending aortic aneurysm rupture potential. Acta Biomater 9:9392\u20139400. https:\/\/doi.org\/10.1016\/j.actbio.2013.07.044","journal-title":"Acta Biomater"},{"key":"1917_CR26","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1016\/j.athoracsur.2015.07.028","volume":"101","author":"G Martufi","year":"2016","unstructured":"Martufi G, Forneris A, Appoo JJ, Di Martino ES (2016) Is there a role for biomechanical engineering in helping to elucidate the risk profile of the thoracic aorta? Ann Thorac Surg 101:390\u2013398. https:\/\/doi.org\/10.1016\/j.athoracsur.2015.07.028","journal-title":"Ann Thorac Surg"},{"key":"1917_CR27","doi-asserted-by":"publisher","first-page":"e383","DOI":"10.1016\/j.jtcvs.2021.06.019","volume":"162","author":"HI Michelena","year":"2021","unstructured":"Michelena HI et al (2021) International consensus statement on nomenclature and classification of the congenital bicuspid aortic valve and its aortopathy, for clinical, surgical, interventional and research purposes. J Thorac Cardiovasc Surg 162:e383\u2013e414. https:\/\/doi.org\/10.1016\/j.jtcvs.2021.06.019","journal-title":"J Thorac Cardiovasc Surg"},{"key":"1917_CR28","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2021.110297","volume":"119","author":"SI Murtada","year":"2021","unstructured":"Murtada SI, Kawamura Y, Weiss D, Humphrey JD (2021) Differential biomehcanical responses of elastic and muscular arteries to angiotensin II-induced hypertension. J Biomech 119:110297. https:\/\/doi.org\/10.1016\/j.jbiomech.2021.110297","journal-title":"J Biomech"},{"key":"1917_CR29","doi-asserted-by":"publisher","first-page":"7927","DOI":"10.1016\/j.actbio.2013.04.021","volume":"9","author":"T Pham","year":"2013","unstructured":"Pham T, Martin C, Elefteriades J, Sun W (2013) Biomechanical characterization of ascending aortic aneurysm with concomitant bicuspid aortic valve and bovine aortic arch. Acta Biomater 9:7927\u20137936. https:\/\/doi.org\/10.1016\/j.actbio.2013.04.021","journal-title":"Acta Biomater"},{"key":"1917_CR30","doi-asserted-by":"publisher","first-page":"2147","DOI":"10.1016\/j.athoracsur.2013.07.001","volume":"96","author":"JE Pichamuthu","year":"2013","unstructured":"Pichamuthu JE et al (2013) Differential tensile strength and collagen composition in ascending aortic aneurysms by aortic valve phenotype. Ann Thorac Surg 96:2147\u20132154. https:\/\/doi.org\/10.1016\/j.athoracsur.2013.07.001","journal-title":"Ann Thorac Surg"},{"key":"1917_CR31","doi-asserted-by":"publisher","first-page":"2586","DOI":"10.1016\/j.ajpath.2014.05.014","volume":"184","author":"DL Rateri","year":"2014","unstructured":"Rateri DL et al (2014) Angiotensin II induces region-specific medial disruption during evolution of ascending aortic aneurysms. Am J Pathol 184:2586\u20132595. https:\/\/doi.org\/10.1016\/j.ajpath.2014.05.014","journal-title":"Am J Pathol"},{"key":"1917_CR32","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2021.750656","volume":"9","author":"MY Salmasi","year":"2021","unstructured":"Salmasi MY et al (2021) High wall shear stress can predict wall degradation in ascending aortic aneurysms: an integrated biomehcanics study. Front Bioeng Biotechnol 9:750656. https:\/\/doi.org\/10.3389\/fbioe.2021.750656","journal-title":"Front Bioeng Biotechnol"},{"key":"1917_CR33","doi-asserted-by":"publisher","first-page":"3757","DOI":"10.1016\/j.jbiomech.2015.08.028","volume":"48","author":"SG Sassani","year":"2015","unstructured":"Sassani SG, Tsangaris S, Sokolis DP (2015) Layer- and region-specific material characterization of ascending thoracic aortic aneurysms by microstructure-based models. J Biomech 48:3757\u20133765. https:\/\/doi.org\/10.1016\/j.jbiomech.2015.08.028","journal-title":"J Biomech"},{"key":"1917_CR34","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1016\/j.jmbbm.2016.08.006","volume":"64","author":"N Shahmansouri","year":"2016","unstructured":"Shahmansouri N et al (2016) Evaluating ascending aortic aneurysm tissue toughness: Dependence on collagen and elastin contents. J Mech Behav Biomed Mater 64:262\u2013271. https:\/\/doi.org\/10.1016\/j.jmbbm.2016.08.006","journal-title":"J Mech Behav Biomed Mater"},{"key":"1917_CR35","doi-asserted-by":"publisher","first-page":"534","DOI":"10.1093\/ejcts\/ezy308","volume":"55","author":"Y Shan","year":"2019","unstructured":"Shan Y et al (2019) Aortic stenosis exacerbates flow aberrations related to the bicuspid aortic valve fusion pattern and the aortopathy phenotype. Eur J Cardiothorac Surg 55:534\u2013542. https:\/\/doi.org\/10.1093\/ejcts\/ezy308","journal-title":"Eur J Cardiothorac Surg"},{"key":"1917_CR36","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2021.110542","volume":"125","author":"T Sigaeva","year":"2021","unstructured":"Sigaeva T, Sattari S, Polzer S, Appoo JJ, Di Martino ES (2021) Biomechanical properties of ascending aortic aneurysms: Quantification of inter- and intra-patient variability. J Biomech 125:110542. https:\/\/doi.org\/10.1016\/j.jbiomech.2021.110542","journal-title":"J Biomech"},{"key":"1917_CR37","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1007\/s10237-016-0848-4","volume":"16","author":"M Smoljki\u0107","year":"2017","unstructured":"Smoljki\u0107 M et al (2017) Biomechanical characterization of ascending aortic aneurysms. Biomech Model Mechanobiol 16:705\u2013720. https:\/\/doi.org\/10.1007\/s10237-016-0848-4","journal-title":"Biomech Model Mechanobiol"},{"key":"1917_CR38","doi-asserted-by":"publisher","first-page":"1227","DOI":"10.1007\/s11517-012-0949-x","volume":"50","author":"DP Sokolis","year":"2012","unstructured":"Sokolis DP, Kritharis EP, Iliopoulos DC, Kritharis EP (2012) Effect of layer heterogeneity on the biomechanical properties of ascending thoracic aortic aneurysms. Med Biol Eng Comput 50:1227\u20131237. https:\/\/doi.org\/10.1007\/s11517-012-0949-x","journal-title":"Med Biol Eng Comput"},{"key":"1917_CR39","doi-asserted-by":"publisher","first-page":"021007\u20131","DOI":"10.1115\/1.2898733","volume":"130","author":"G Sommer","year":"2008","unstructured":"Sommer G, Gasser TC, Regitnig P, Auer M, Holzapfel GA (2008) Dissection properties of the human aortic media: an experimental study. J Biomech Eng 130:021007-1\u201321012. https:\/\/doi.org\/10.1115\/1.2898733","journal-title":"J Biomech Eng"},{"key":"1917_CR40","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1016\/j.ejvs.2011.02.017","volume":"42","author":"J Tong","year":"2011","unstructured":"Tong J, Cohnert T, Regitnig P, Holzapfel GA (2011) Effects of age on the elastic properties of the intraluminal thrombus and the thrombus-covered wall in abdominal aortic aneurysms: biaxial extension behavior and material modeling. Eur J Vasc Endovasc Surg 42:207\u2013219. https:\/\/doi.org\/10.1016\/j.ejvs.2011.02.017","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"1917_CR41","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1007\/s10439-017-1955-9","volume":"46","author":"J Tong","year":"2018","unstructured":"Tong J, Yang F, Li X, Xu X, Wang GX (2018) Mechanical characterization and material modeling of diabetic aortas in a rabbit model. Ann Biomed Eng 46:429\u2013442. https:\/\/doi.org\/10.1007\/s10439-017-1955-9","journal-title":"Ann Biomed Eng"},{"key":"1917_CR42","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2023.111615","volume":"154","author":"J Tong","year":"2023","unstructured":"Tong J, Xin YF, Zhang Z, Xu X, Li T (2023) Effect of hypertension on the delamination and tensile strength of ascending thoracic aortic aneurysm with a focus on right lateral region. J Biomech 154:111615. https:\/\/doi.org\/10.1016\/j.jbiomech.2023.111615","journal-title":"J Biomech"},{"key":"1917_CR43","doi-asserted-by":"publisher","first-page":"1920","DOI":"10.1056\/NEJMra1207059","volume":"370","author":"S Verma","year":"2014","unstructured":"Verma S, Siu SC (2014) Aortic dilatation in patients with bicuspid aortic valve. N Engl J Med 370:1920\u20131929. https:\/\/doi.org\/10.1056\/NEJMra1207059","journal-title":"N Engl J Med"},{"key":"1917_CR44","first-page":"275","volume":"27","author":"Z Wang","year":"2018","unstructured":"Wang Z, Xuan Y, Guccione JM, Tseng EE, Ge L (2018) Impact of patient-specific material properties on aneurysm wall stress: finite element study. J Heart Valve Dis 27:275\u2013284","journal-title":"J Heart Valve Dis"},{"key":"1917_CR45","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmbbm.2022.105295","volume":"132","author":"X Xu","year":"2022","unstructured":"Xu X et al (2022) Mechanical characterization and material modleing of ascending aortic aneurysm with different bicuspid aortic cusp fusion morphologies. J Mech Behav Biomed Mater 132:105295. https:\/\/doi.org\/10.1016\/j.jmbbm.2022.105295","journal-title":"J Mech Behav Biomed Mater"},{"key":"1917_CR46","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.jtcvs.2016.09.040","volume":"153","author":"P Youssefi","year":"2017","unstructured":"Youssefi P et al (2017) Patient-specific computational fluid dynamics-assessment of aortic hemodynamics in a spectrum of aortic valve pathologies. J Thorac Cardiovasc Surg 153:8\u201320. https:\/\/doi.org\/10.1016\/j.jtcvs.2016.09.040","journal-title":"J Thorac Cardiovasc Surg"}],"container-title":["Biomechanics and Modeling in Mechanobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10237-024-01917-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10237-024-01917-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10237-024-01917-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T12:19:01Z","timestamp":1746533941000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10237-024-01917-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,26]]},"references-count":46,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["1917"],"URL":"https:\/\/doi.org\/10.1007\/s10237-024-01917-4","relation":{},"ISSN":["1617-7959","1617-7940"],"issn-type":[{"value":"1617-7959","type":"print"},{"value":"1617-7940","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,26]]},"assertion":[{"value":"12 September 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 December 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 December 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This study was approved by Ethics Committee of Shanghai East Hospital, Tongji University School of Medicine, in accordance with the Helsinki Declaration (Ref. 2019-TJDX-125), and all participants provided written informed consent.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}}]}}