{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T15:18:09Z","timestamp":1785251889057,"version":"3.55.0"},"reference-count":40,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2021,6,30]],"date-time":"2021-06-30T00:00:00Z","timestamp":1625011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,6,30]],"date-time":"2021-06-30T00:00:00Z","timestamp":1625011200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100010909","name":"Young Scientists Fund","doi-asserted-by":"publisher","award":["81701593"],"award-info":[{"award-number":["81701593"]}],"id":[{"id":"10.13039\/501100010909","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Exp Med"],"published-print":{"date-parts":[[2022,5]]},"DOI":"10.1007\/s10238-021-00737-5","type":"journal-article","created":{"date-parts":[[2021,6,30]],"date-time":"2021-06-30T14:03:02Z","timestamp":1625061782000},"page":"277-283","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Associations between sarcoidosis, autoimmune diseases, and autoantibodies: a single-center retrospective study in China"],"prefix":"10.1007","volume":"22","author":[{"given":"Tian-Yan","family":"Shi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Hong","family":"Wen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xu-Hua","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9748-0068","authenticated-orcid":false,"given":"Yue-Wu","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,6,30]]},"reference":[{"key":"737_CR1","doi-asserted-by":"crossref","unstructured":"Jain R, Yadav D, Puranik N, Guleria R, Jin JO. Sarcoidosis: causes, diagnosis, clinical features, and treatments. J Clin Med. 2020;9(4).","DOI":"10.3390\/jcm9041081"},{"key":"737_CR2","doi-asserted-by":"publisher","first-page":"l5553","DOI":"10.1136\/bmj.l5553","volume":"367","author":"DA Culver","year":"2019","unstructured":"Culver DA, Judson MA. New advances in the management of pulmonary sarcoidosis. BMJ. 2019;367:l5553.","journal-title":"BMJ"},{"key":"737_CR3","doi-asserted-by":"crossref","unstructured":"Kaiser Y, Eklund A, Grunewald J. Moving target: shifting the focus to pulmonary sarcoidosis as an autoimmune spectrum disorder. Eur Respir J. 2019;54(1).","DOI":"10.1183\/13993003.021532018"},{"issue":"1","key":"737_CR4","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1093\/rheumatology\/36.1.117","volume":"36","author":"M De Bandt","year":"1997","unstructured":"De Bandt M, Perrot S, Masson C, Meyer O. Systemic sclerosis and sarcoidosis, a report of five cases. Br J Rheumatol. 1997;36(1):117\u20139.","journal-title":"Br J Rheumatol"},{"issue":"5","key":"737_CR5","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1097\/MCP.0000000000000500","volume":"24","author":"P Korsten","year":"2018","unstructured":"Korsten P, Tampe B, Konig MF, Nikiphorou E. Sarcoidosis and autoimmune diseases: differences, similarities and overlaps. Curr Opin Pulm Med. 2018;24(5):504\u201312.","journal-title":"Curr Opin Pulm Med"},{"issue":"1","key":"737_CR6","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1136\/annrheumdis-2016-210571","volume":"76","author":"CH Shiboski","year":"2017","unstructured":"Shiboski CH, Shiboski SC, Seror R, Criswell LA, Labetoulle M, Lietman TM, Rasmussen A, Scofield H, Vitali C, Bowman SJ, et al. 2016 American College of Rheumatology\/European League Against Rheumatism classification criteria for primary Sj\u00f6gren\u2019s syndrome: a consensus and data-driven methodology involving three international patient cohorts. Ann Rheum Dis. 2017;76(1):9\u201316.","journal-title":"Ann Rheum Dis"},{"issue":"4","key":"737_CR7","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1002\/acr.21591","volume":"64","author":"SC Shiboski","year":"2012","unstructured":"Shiboski SC, Shiboski CH, Criswell L, Baer A, Challacombe S, Lanfranchi H, Schi\u00f8dt M, Umehara H, Vivino F, Zhao Y, et al. American College of Rheumatology classification criteria for Sj\u00f6gren\u2019s syndrome: a data-driven, expert consensus approach in the Sj\u00f6gren\u2019s International Collaborative Clinical Alliance cohort. Arthritis Care Res (Hoboken). 2012;64(4):475\u201387.","journal-title":"Arthritis Care Res (Hoboken)"},{"issue":"8","key":"737_CR8","doi-asserted-by":"publisher","first-page":"2677","DOI":"10.1002\/art.34473","volume":"64","author":"M Petri","year":"2012","unstructured":"Petri M, Orbai AM, Alarc\u00f3n GS, Gordon C, Merrill JT, Fortin PR, Bruce IN, Isenberg D, Wallace DJ, Nived O, et al. Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus. Arthritis Rheum. 2012;64(8):2677\u201386.","journal-title":"Arthritis Rheum"},{"issue":"9","key":"737_CR9","doi-asserted-by":"publisher","first-page":"2569","DOI":"10.1002\/art.27584","volume":"62","author":"D Aletaha","year":"2010","unstructured":"Aletaha D, Neogi T, Silman AJ, Funovits J, Felson DT, Bingham CO 3rd, Birnbaum NS, Burmester GR, Bykerk VP, Cohen MD, et al. 2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology\/European League Against Rheumatism collaborative initiative. Arthritis Rheum. 2010;62(9):2569\u201381.","journal-title":"Arthritis Rheum"},{"issue":"2","key":"737_CR10","first-page":"118","volume":"9","author":"J Ma\u00f1\u00e1","year":"1992","unstructured":"Ma\u00f1\u00e1 J, Badrinas F, Morera J, Fit\u00e9 E, Manresa F, Fern\u00e1ndez-Nogu\u00e9s F. Sarcoidosis in Spain. Sarcoidosis. 1992;9(2):118\u201322.","journal-title":"Sarcoidosis"},{"issue":"12","key":"737_CR11","first-page":"617","volume":"20","author":"M Alcoba Leza","year":"2003","unstructured":"Alcoba Leza M, P\u00e9rez-Sim\u00f3n MR, Guerra Laso JM, Carro Fern\u00e1ndez JA, Alonso Fern\u00e1ndez MA, Blanco Iglesias B, Bueno Su\u00e1rez P, Muinelo Voces I. Sarcoidosis in a sanitary area at Leon (Spain). Epidemiology and clinical features. An Med Int. 2003;20(12):617\u201320.","journal-title":"An Med Int"},{"issue":"33\u201334","key":"737_CR12","first-page":"565","volume":"113","author":"A Prasse","year":"2016","unstructured":"Prasse A. The diagnosis, differential diagnosis, and treatment of Sarcoidosis. Dtsch Arztebl Int. 2016;113(33\u201334):565\u201374.","journal-title":"Dtsch Arztebl Int"},{"issue":"1","key":"737_CR13","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1172\/JCI110036","volume":"67","author":"GW Hunninghake","year":"1981","unstructured":"Hunninghake GW, Crystal RG. Mechanisms of hypergammaglobulinemia in pulmonary sarcoidosis. Site of increased antibody production and role of T lymphocytes. J Clin Invest. 1981;67(1):86\u201392.","journal-title":"J Clin Invest"},{"issue":"5","key":"737_CR14","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1097\/MCP.0000000000000715","volume":"26","author":"EV Arkema","year":"2020","unstructured":"Arkema EV, Cozier YC. Sarcoidosis epidemiology: recent estimates of incidence, prevalence and risk factors. Curr Opin Pulm Med. 2020;26(5):527\u201334.","journal-title":"Curr Opin Pulm Med"},{"issue":"4","key":"737_CR15","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1111\/joim.12395","volume":"278","author":"L Wang","year":"2015","unstructured":"Wang L, Wang FS, Gershwin ME. Human autoimmune diseases: a comprehensive update. J Int Med. 2015;278(4):369\u201395.","journal-title":"J Int Med"},{"issue":"1","key":"737_CR16","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jaut.2007.05.002","volume":"29","author":"WW Eaton","year":"2007","unstructured":"Eaton WW, Rose NR, Kalaydjian A, Pedersen MG, Mortensen PB. Epidemiology of autoimmune diseases in Denmark. J Autoimmun. 2007;29(1):1\u20139.","journal-title":"J Autoimmun"},{"issue":"3","key":"737_CR17","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1006\/clin.1997.4412","volume":"84","author":"DL Jacobson","year":"1997","unstructured":"Jacobson DL, Gange SJ, Rose NR, Graham NM. Epidemiology and estimated population burden of selected autoimmune diseases in the United States. Clin Immunol Immunopathol. 1997;84(3):223\u201343.","journal-title":"Clin Immunol Immunopathol"},{"issue":"6","key":"737_CR18","first-page":"1052","volume":"37","author":"P Brito-Zer\u00f3n","year":"2019","unstructured":"Brito-Zer\u00f3n P, Kostov B, Superville D, Baughman RP, Ramos-Casals M. Geoepidemiological big data approach to sarcoidosis: geographical and ethnic determinants. Clin Exp Rheumatol. 2019;37(6):1052\u201364.","journal-title":"Clin Exp Rheumatol"},{"issue":"2","key":"737_CR19","first-page":"112","volume":"33","author":"M Sawahata","year":"2016","unstructured":"Sawahata M, Sugiyama Y. An epidemiological perspective of the pathology and etiology of sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis. 2016;33(2):112\u20136.","journal-title":"Sarcoidosis Vasc Diffuse Lung Dis"},{"issue":"4","key":"737_CR20","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1111\/1346-8138.13654","volume":"44","author":"CH Wu","year":"2017","unstructured":"Wu CH, Chung PI, Wu CY, Chen YT, Chiu YW, Chang YT, Liu HN. Comorbid autoimmune diseases in patients with sarcoidosis: a nationwide case-control study in Taiwan. J Dermatol. 2017;44(4):423\u201330.","journal-title":"J Dermatol"},{"issue":"2","key":"737_CR21","doi-asserted-by":"publisher","first-page":"106","DOI":"10.4081\/reumatismo.2018.1017","volume":"70","author":"H Semiz","year":"2018","unstructured":"Semiz H, Yalcin M, Kobak S. Coexistence of sarcoidosis and Hashimoto thyroiditis. Reumatismo. 2018;70(2):106\u201310.","journal-title":"Reumatismo"},{"issue":"4","key":"737_CR22","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1046\/j.1365-2265.1997.1630976.x","volume":"46","author":"H Nakamura","year":"1997","unstructured":"Nakamura H, Genma R, Mikami T, Kitahara A, Natsume H, Andoh S, Nagasawa S, Nishiyama K, Chida K, Sato A, et al. High incidence of positive autoantibodies against thyroid peroxidase and thyroglobulin in patients with sarcoidosis. Clin Endocrinol (Oxf). 1997;46(4):467\u201372.","journal-title":"Clin Endocrinol (Oxf)"},{"key":"737_CR23","doi-asserted-by":"publisher","first-page":"177","DOI":"10.3389\/fendo.2017.00177","volume":"8","author":"P Fazzi","year":"2017","unstructured":"Fazzi P, Fallahi P, Ferrari SM. Sarcoidosis and thyroid autoimmunity. Front Endocrinol (Lausanne). 2017;8:177.","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"2","key":"737_CR24","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1097\/01.md.0000121237.98962.1e","volume":"83","author":"M Ramos-Casals","year":"2004","unstructured":"Ramos-Casals M, Brito-Zer\u00f3n P, Garc\u00eda-Carrasco M, Font J. Sarcoidosis or Sj\u00f6gren syndrome? Clues to defining mimicry or coexistence in 59 cases. Medicine (Baltimore). 2004;83(2):85\u201395.","journal-title":"Medicine (Baltimore)"},{"issue":"2","key":"737_CR25","doi-asserted-by":"publisher","first-page":"259","DOI":"10.46497\/ArchRheumatol.2020.7649","volume":"35","author":"F Yildiz","year":"2020","unstructured":"Yildiz F, Kobak \u015e, Sem\u0130z H, Orman M. Concomitant autoimmune diseases in patients with Sarcoidosis in Turkey. Arch Rheumatol. 2020;35(2):259\u201363.","journal-title":"Arch Rheumatol"},{"issue":"1","key":"737_CR26","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1186\/s12891-017-1525-1","volume":"18","author":"MJ Antonelli","year":"2017","unstructured":"Antonelli MJ, Magrey M. Sacroiliitis mimics: a case report and review of the literature. BMC Musculoskelet Disord. 2017;18(1):170.","journal-title":"BMC Musculoskelet Disord"},{"issue":"10","key":"737_CR27","doi-asserted-by":"publisher","first-page":"e109632","DOI":"10.1371\/journal.pone.0109632","volume":"9","author":"U Khalid","year":"2014","unstructured":"Khalid U, Gislason GH, Hansen PR. Sarcoidosis in patients with psoriasis: a population-based cohort study. PLoS ONE. 2014;9(10):e109632.","journal-title":"PLoS ONE"},{"issue":"1003","key":"737_CR28","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1136\/pgmj.2008.067769","volume":"85","author":"N Rajoriya","year":"2009","unstructured":"Rajoriya N, Wotton CJ, Yeates DG, Travis SP, Goldacre MJ. Immune-mediated and chronic inflammatory disease in people with sarcoidosis: disease associations in a large UK database. Postgrad Med J. 2009;85(1003):233\u20137.","journal-title":"Postgrad Med J"},{"issue":"11","key":"737_CR29","doi-asserted-by":"publisher","first-page":"21463","DOI":"10.3390\/ijms141121463","volume":"14","author":"H Huang","year":"2013","unstructured":"Huang H, Lu Z, Jiang C, Liu J, Wang Y, Xu Z. Imbalance between Th17 and regulatory T-Cells in sarcoidosis. Int J Mol Sci. 2013;14(11):21463\u201373.","journal-title":"Int J Mol Sci"},{"key":"737_CR30","doi-asserted-by":"publisher","first-page":"2933","DOI":"10.3389\/fimmu.2019.02933","volume":"10","author":"AA Starshinova","year":"2019","unstructured":"Starshinova AA, Malkova AM, Basantsova NY, Zinchenko YS, Kudryavtsev IV, Ershov GA, Soprun LA, Mayevskaya VA, Churilov LP, Yablonskiy PK. Sarcoidosis as an autoimmune disease. Front Immunol. 2019;10:2933.","journal-title":"Front Immunol"},{"issue":"1","key":"737_CR31","doi-asserted-by":"publisher","first-page":"1059","DOI":"10.1038\/s41598-020-57741-0","volume":"10","author":"I Kudryavtsev","year":"2020","unstructured":"Kudryavtsev I, Serebriakova M, Starshinova A, Zinchenko Y, Basantsova N, Malkova A, Soprun L, Churilov LP, Toubi E, Yablonskiy P, et al. Imbalance in B cell and T follicular helper cell subsets in pulmonary Sarcoidosis. Sci Rep. 2020;10(1):1059.","journal-title":"Sci Rep"},{"issue":"10","key":"737_CR32","doi-asserted-by":"publisher","first-page":"2833","DOI":"10.1007\/s10067-018-4183-2","volume":"37","author":"M Ando","year":"2018","unstructured":"Ando M, Goto A, Takeno Y, Yamasue M, Komiya K, Umeki K, Nureki SI, Miyazaki E, Kadota JI. Significant elevation of the levels of B-cell activating factor (BAFF) in patients with sarcoidosis. Clin Rheumatol. 2018;37(10):2833\u20138.","journal-title":"Clin Rheumatol"},{"issue":"6","key":"737_CR33","first-page":"317","volume":"115","author":"C Bray","year":"2016","unstructured":"Bray C, Bell LN, Liang H, Haykal R, Kaiksow F, Mazza JJ, Yale SH. Erythrocyte sedimentation rate and C-reactive protein measurements and their relevance in clinical medicine. WMJ. 2016;115(6):317\u201321.","journal-title":"WMJ"},{"issue":"4","key":"737_CR34","doi-asserted-by":"publisher","first-page":"e0193122","DOI":"10.1371\/journal.pone.0193122","volume":"13","author":"N Belhomme","year":"2018","unstructured":"Belhomme N, Jouneau S, Bouzill\u00e9 G, Decaux O, Lederlin M, Guillot S, Perlat A, J\u00e9go P. Role of serum immunoglobulins for predicting sarcoidosis outcome: A cohort study. PLoS ONE. 2018;13(4):e0193122.","journal-title":"PLoS ONE"},{"issue":"5\u20136","key":"737_CR35","first-page":"99","volume":"49","author":"T Cagatay","year":"2003","unstructured":"Cagatay T, Bilir M, Gulbaran M, Papila C, Cagatay P. The immunoglobulin and complement levels in the active pulmonary sarcoidosis. Kobe J Med Sci. 2003;49(5\u20136):99\u2013106.","journal-title":"Kobe J Med Sci"},{"key":"737_CR36","doi-asserted-by":"publisher","first-page":"1516","DOI":"10.3389\/fimmu.2018.01516","volume":"9","author":"AJ Kinloch","year":"2018","unstructured":"Kinloch AJ, Kaiser Y, Wolfgeher D, Ai J, Eklund A, Clark MR, Grunewald J. In situ humoral immunity to Vimentin in HLA-DRB1*03(+) patients with pulmonary Sarcoidosis. Front Immunol. 2018;9:1516.","journal-title":"Front Immunol"},{"issue":"5","key":"737_CR37","doi-asserted-by":"publisher","first-page":"977","DOI":"10.1016\/0002-9343(87)90664-4","volume":"83","author":"EB Keeffe","year":"1987","unstructured":"Keeffe EB. Sarcoidosis and primary biliary cirrhosis. Literature review and illustrative case. Am J Med. 1987;83(5):977\u201380.","journal-title":"Am J Med"},{"key":"737_CR38","first-page":"351852","volume":"2014","author":"S Kobak","year":"2014","unstructured":"Kobak S, Yilmaz H, Sever F, Duran A, Sen N, Karaarslan A. The prevalence of antinuclear antibodies in patients with sarcoidosis. Autoimmune Dis. 2014;2014:351852.","journal-title":"Autoimmune Dis"},{"issue":"5","key":"737_CR39","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1016\/S0049-0172(00)80019-0","volume":"29","author":"I Weinberg","year":"2000","unstructured":"Weinberg I, Vasiliev L, Gotsman I. Anti-dsDNA antibodies in sarcoidosis. Semin Arthritis Rheum. 2000;29(5):328\u201331.","journal-title":"Semin Arthritis Rheum"},{"issue":"3","key":"737_CR40","first-page":"206","volume":"31","author":"S Kobak","year":"2014","unstructured":"Kobak S, Ylmaz H, Sever F, Duran A, Sen N. Anti-cyclic citrullinated peptide antibodies in patients with sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis. 2014;31(3):206\u201310.","journal-title":"Sarcoidosis Vasc Diffuse Lung Dis"}],"container-title":["Clinical and Experimental Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10238-021-00737-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10238-021-00737-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10238-021-00737-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,16]],"date-time":"2022-05-16T16:15:43Z","timestamp":1652717743000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10238-021-00737-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,30]]},"references-count":40,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["737"],"URL":"https:\/\/doi.org\/10.1007\/s10238-021-00737-5","relation":{},"ISSN":["1591-9528"],"issn-type":[{"value":"1591-9528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,30]]},"assertion":[{"value":"10 March 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 June 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 June 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}