{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T11:41:58Z","timestamp":1793014918765,"version":"4.5.0"},"reference-count":171,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T00:00:00Z","timestamp":1756252800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T00:00:00Z","timestamp":1756252800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Exp Med"],"DOI":"10.1007\/s10238-025-01852-3","type":"journal-article","created":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T13:43:53Z","timestamp":1756302233000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Impact of exercise on immune cell infiltration in muscle tissue: implications for muscle repair and chronic disease"],"prefix":"10.1007","volume":"25","author":[{"given":"Yiping","family":"Su","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhanguo","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,8,27]]},"reference":[{"issue":"12","key":"1852_CR1","doi-asserted-by":"crossref","first-page":"210110","DOI":"10.1098\/rsob.210110","volume":"11","author":"T Molina","year":"2021","unstructured":"Molina T, Fabre P, Dumont NA. Fibro-adipogenic progenitors in skeletal muscle homeostasis, regeneration and diseases. Open Biol. 2021;11(12):210110.","journal-title":"Open Biol"},{"issue":"12","key":"1852_CR2","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1139\/apnm-2024-0128","volume":"49","author":"J Paquin","year":"2024","unstructured":"Paquin J, Tremblay R, Islam H, Riesco E, Marcotte-Ch\u00e9nard A, Dionne I. Resistance training, skeletal muscle hypertrophy, and glucose homeostasis: how related are they? A systematic review and meta-analysis. Appl Physiol Nutr Metab. 2024;49(12):1622\u201335.","journal-title":"Appl Physiol Nutr Metab"},{"issue":"8","key":"1852_CR3","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1111\/febs.16693","volume":"291","author":"N Caballero-S\u00e1nchez","year":"2024","unstructured":"Caballero-S\u00e1nchez N, Alonso-Alonso S, Nagy L. Regenerative inflammation: when immune cells help to re-build tissues. FEBS J. 2024;291(8):1597\u2013614.","journal-title":"FEBS J"},{"issue":"6","key":"1852_CR4","doi-asserted-by":"crossref","first-page":"3265","DOI":"10.3390\/ijms22063265","volume":"22","author":"N Ziemkiewicz","year":"2021","unstructured":"Ziemkiewicz N, Hilliard G, Pullen NA, Garg K. The role of innate and adaptive immune cells in skeletal muscle regeneration. Int J Mol Sci. 2021;22(6):3265.","journal-title":"Int J Mol Sci"},{"issue":"2","key":"1852_CR5","doi-asserted-by":"crossref","first-page":"e13312","DOI":"10.1111\/acel.13312","volume":"20","author":"SW Tobin","year":"2021","unstructured":"Tobin SW, Alibhai FJ, Wlodarek L, Yeganeh A, Millar S, Wu J, et al. Delineating the relationship between immune system aging and myogenesis in muscle repair. Aging Cell. 2021;20(2):e13312.","journal-title":"Aging Cell"},{"issue":"8","key":"1852_CR6","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/s41419-022-05142-8","volume":"13","author":"J Wu","year":"2022","unstructured":"Wu J, Ren B, Wang D, Lin H. Regulatory t cells in skeletal muscle repair and regeneration: recent insights. Cell Death Dis. 2022;13(8):680.","journal-title":"Cell Death Dis"},{"issue":"4","key":"1852_CR7","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1038\/s41577-023-00943-0","volume":"24","author":"C Fiuza-Luces","year":"2024","unstructured":"Fiuza-Luces C, Valenzuela PL, G\u00e1lvez BG, Ram\u00edrez M, L\u00f3pez-Soto A, Simpson RJ, et al. The effect of physical exercise on anticancer immunity. Nat Rev Immunol. 2024;24(4):282\u201393.","journal-title":"Nat Rev Immunol"},{"issue":"9","key":"1852_CR8","doi-asserted-by":"crossref","first-page":"2653","DOI":"10.1111\/all.15328","volume":"77","author":"M Kurowski","year":"2022","unstructured":"Kurowski M, Seys S, Bonini M, Del Giacco S, Delgado L, Diamant Z, et al. Physical exercise, immune response, and susceptibility to infections\u2014current knowledge and growing research areas. Allergy. 2022;77(9):2653\u201364.","journal-title":"Allergy"},{"key":"1852_CR9","doi-asserted-by":"crossref","first-page":"1133355","DOI":"10.3389\/fimmu.2023.1133355","volume":"14","author":"H Tu","year":"2023","unstructured":"Tu H, Li Y-L. Inflammation balance in skeletal muscle damage and repair. Front Immunol. 2023;14:1133355.","journal-title":"Front Immunol"},{"issue":"1","key":"1852_CR10","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1038\/s41572-023-00469-8","volume":"9","author":"P Edouard","year":"2023","unstructured":"Edouard P, Reurink G, Mackey AL, Lieber RL, Pizzari T, J\u00e4rvinen TA, et al. Traumatic muscle injury. Nat Rev Dis Primers. 2023;9(1):56.","journal-title":"Nat Rev Dis Primers"},{"issue":"1","key":"1852_CR11","doi-asserted-by":"crossref","first-page":"R41","DOI":"10.1152\/ajpregu.00038.2021","volume":"322","author":"ALA Minari","year":"2022","unstructured":"Minari ALA, Thomatieli-Santos RV. From skeletal muscle damage and regeneration to the hypertrophy induced by exercise: what is the role of different macrophage subsets? Am J Physiol-Regul Integr Comp Physiol. 2022;322(1):R41\u201354.","journal-title":"Am J Physiol-Regul Integr Comp Physiol"},{"key":"1852_CR12","doi-asserted-by":"crossref","first-page":"952249","DOI":"10.3389\/fcell.2022.952249","volume":"10","author":"X Wang","year":"2022","unstructured":"Wang X, Zhou L. The many roles of macrophages in skeletal muscle injury and repair. Front Cell Dev Biol. 2022;10:952249.","journal-title":"Front Cell Dev Biol"},{"key":"1852_CR13","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.actbio.2021.04.023","volume":"133","author":"KM Adusei","year":"2021","unstructured":"Adusei KM, Ngo TB, Sadtler K. T lymphocytes as critical mediators in tissue regeneration, fibrosis, and the foreign body response. Acta Biomater. 2021;133:17\u201333.","journal-title":"Acta Biomater"},{"key":"1852_CR14","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1007\/s00421-020-04566-4","volume":"121","author":"I Markus","year":"2021","unstructured":"Markus I, Constantini K, Hoffman J, Bartolomei S, Gepner Y. Exercise-induced muscle damage: mechanism, assessment and nutritional factors to accelerate recovery. Eur J Appl Physiol. 2021;121:969\u201392.","journal-title":"Eur J Appl Physiol"},{"key":"1852_CR15","doi-asserted-by":"crossref","first-page":"987545","DOI":"10.3389\/fnut.2022.987545","volume":"9","author":"F Jiang","year":"2022","unstructured":"Jiang F, Yang R, Xue D, Li R, Tan M, Zeng Z, et al. Effects of a natural nutritional supplement on immune cell infiltration and immune gene expression in exercise-induced injury. Front Nutr. 2022;9:987545.","journal-title":"Front Nutr"},{"issue":"4","key":"1852_CR16","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1007\/s10974-024-09668-6","volume":"45","author":"P Castrogiovanni","year":"2024","unstructured":"Castrogiovanni P, Sanfilippo C, Imbesi R, Lazzarino G, Li Volti G, Tibullo D, et al. Skeletal muscle of young females under resistance exercise exhibits a unique innate immune cell infiltration profile compared to males and elderly individuals. J Muscle Res Cell Motil. 2024;45(4):171\u201390.","journal-title":"J Muscle Res Cell Motil"},{"key":"1852_CR17","first-page":"405","volume-title":"Exercise, aging and frailty: guidelines for increasing function","author":"R Merchant","year":"2021","unstructured":"Merchant R, Morley J, Izquierdo M. Exercise, aging and frailty: guidelines for increasing function. New York: Springer; 2021. p. 405\u20139."},{"key":"1852_CR18","doi-asserted-by":"crossref","first-page":"101755","DOI":"10.1016\/j.molmet.2023.101755","volume":"74","author":"JJ Baechle","year":"2023","unstructured":"Baechle JJ, Chen N, Makhijani P, Winer S, Furman D, Winer DA. Chronic inflammation and the hallmarks of aging. Mol Metab. 2023;74:101755.","journal-title":"Mol Metab"},{"issue":"15","key":"1852_CR19","doi-asserted-by":"crossref","first-page":"8713","DOI":"10.3390\/ijms23158713","volume":"23","author":"M El Assar","year":"2022","unstructured":"El Assar M, \u00c1lvarez-Bustos A, Sosa P, Angulo J, Rodr\u00edguez-Ma\u00f1as L. Effect of physical activity\/exercise on oxidative stress and inflammation in muscle and vascular aging. Int J Mol Sci. 2022;23(15):8713.","journal-title":"Int J Mol Sci"},{"issue":"7","key":"1852_CR20","doi-asserted-by":"crossref","first-page":"65","DOI":"10.2174\/1573399819666221212145712","volume":"19","author":"H Hamasaki","year":"2023","unstructured":"Hamasaki H. Effects of exercise on circulating muscle-related cytokines in adults with type 2 diabetes and\/or obesity. Curr Diabetes Rev. 2023;19(7):65\u201375.","journal-title":"Curr Diabetes Rev"},{"issue":"7","key":"1852_CR21","doi-asserted-by":"crossref","first-page":"e23596","DOI":"10.1096\/fj.202301619R","volume":"38","author":"M Ringleb","year":"2024","unstructured":"Ringleb M, Javelle F, Haunhorst S, Bloch W, Fennen L, Baumgart S, et al. Beyond muscles: investigating immunoregulatory myokines in acute resistance exercise\u2013a systematic review and meta-analysis. FASEB J. 2024;38(7):e23596.","journal-title":"FASEB J"},{"key":"1852_CR22","doi-asserted-by":"crossref","first-page":"1288537","DOI":"10.3389\/fimmu.2023.1288537","volume":"14","author":"M Khalafi","year":"2024","unstructured":"Khalafi M, Maleki AH, Symonds ME, Sakhaei MH, Rosenkranz SK, Ehsanifar M, et al. Interleukin-15 responses to acute and chronic exercise in adults: a systematic review and meta-analysis. Front Immunol. 2024;14:1288537.","journal-title":"Front Immunol"},{"issue":"12","key":"1852_CR23","doi-asserted-by":"crossref","first-page":"5729","DOI":"10.52711\/0974-360X.2024.00872","volume":"17","author":"B Prabowo","year":"2024","unstructured":"Prabowo B, Maskoen AM, Budiarto A, Setiawatie E, Ira K, Harmaz Y, et al. Role of IL-1\u03b2, IL-6, IL-10, IgG, IgA, PMN, macrophage, and cortisol on psychological stress mechanisms in periodontal disorders. Res J Pharm Technol. 2024;17(12):5729\u201337.","journal-title":"Res J Pharm Technol"},{"issue":"1","key":"1852_CR24","doi-asserted-by":"crossref","first-page":"2535","DOI":"10.1038\/s41598-023-29406-1","volume":"13","author":"M Rahmati","year":"2023","unstructured":"Rahmati M, Shariatzadeh Joneydi M, Koyanagi A, Yang G, Ji B, Won Lee S, et al. Resistance training restores skeletal muscle atrophy and satellite cell content in an animal model of Alzheimer\u2019s disease. Sci Rep. 2023;13(1):2535.","journal-title":"Sci Rep"},{"issue":"9","key":"1852_CR25","doi-asserted-by":"crossref","first-page":"e22500","DOI":"10.1096\/fj.202200398RR","volume":"36","author":"AC Thomas","year":"2022","unstructured":"Thomas AC, Brown A, Hatt AA, Manta K, Costa-Parke A, Kamal M, et al. Short-term aerobic conditioning prior to resistance training augments muscle hypertrophy and satellite cell content in healthy young men and women. FASEB J. 2022;36(9):e22500.","journal-title":"FASEB J"},{"issue":"2","key":"1852_CR26","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1093\/cei\/uxac076","volume":"211","author":"BS Hanna","year":"2023","unstructured":"Hanna BS, Yaghi OK, Langston PK, Mathis D. The potential for Treg-enhancing therapies in tissue, in particular skeletal muscle, regeneration. Clin Exp Immunol. 2023;211(2):138\u201348.","journal-title":"Clin Exp Immunol"},{"issue":"10","key":"1852_CR27","doi-asserted-by":"crossref","first-page":"e74722","DOI":"10.1371\/journal.pone.0074722","volume":"8","author":"C Perry","year":"2013","unstructured":"Perry C, Pick M, Bdolach N, Hazan-Halevi I, Kay S, Berr I, et al. Endurance exercise diverts the balance between Th17 cells and regulatory T cells. PLoS ONE. 2013;8(10):e74722.","journal-title":"PLoS ONE"},{"key":"1852_CR28","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12885-019-5745-7","volume":"19","author":"A Hagar","year":"2019","unstructured":"Hagar A, Wang Z, Koyama S, Serrano JA, Melo L, Vargas S, et al. Endurance training slows breast tumor growth in mice by suppressing Treg cells recruitment to tumors. BMC Cancer. 2019;19:1\u201310.","journal-title":"BMC Cancer"},{"issue":"11","key":"1852_CR29","doi-asserted-by":"crossref","first-page":"2575","DOI":"10.1007\/s00421-023-05251-y","volume":"123","author":"S Proschinger","year":"2023","unstructured":"Proschinger S, Schenk A, We\u00dfels I, Donath L, Rappelt L, Metcalfe AJ, et al. Intensity-and time-matched acute interval and continuous endurance exercise similarly induce an anti-inflammatory environment in recreationally active runners: focus on PD-1 expression in Tregs and the IL-6\/IL-10 axis. Eur J Appl Physiol. 2023;123(11):2575\u201384.","journal-title":"Eur J Appl Physiol"},{"key":"1852_CR30","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1590\/S1517-86922012000300015","volume":"18","author":"R Terra","year":"2012","unstructured":"Terra R, Silva SAGd, Pinto VS, Dutra PML. Effect of exercise on immune system: response, adaptation and cell signaling. Rev Bras Med Esporte. 2012;18:208\u201314.","journal-title":"Rev Bras Med Esporte"},{"issue":"1","key":"1852_CR31","first-page":"107805","volume":"2013","author":"SM Reyna","year":"2013","unstructured":"Reyna SM, Tantiwong P, Cersosimo E, DeFronzo RA, Sriwijitkamol A, Musi N. Short-term exercise training improves insulin sensitivity but does not inhibit inflammatory pathways in immune cells from insulin-resistant subjects. J Diabetes Res. 2013;2013(1):107805.","journal-title":"J Diabetes Res"},{"key":"1852_CR32","doi-asserted-by":"crossref","first-page":"101611","DOI":"10.1016\/j.arr.2022.101611","volume":"77","author":"T Wang","year":"2022","unstructured":"Wang T. Searching for the link between inflammaging and sarcopenia. Ageing Res Rev. 2022;77:101611.","journal-title":"Ageing Res Rev"},{"key":"1852_CR33","doi-asserted-by":"crossref","first-page":"111931","DOI":"10.1016\/j.exger.2022.111931","volume":"168","author":"Z Liang","year":"2022","unstructured":"Liang Z, Zhang T, Liu H, Li Z, Peng L, Wang C, et al. Inflammaging: the ground for sarcopenia? Exp Gerontol. 2022;168:111931.","journal-title":"Exp Gerontol"},{"issue":"23","key":"1852_CR34","doi-asserted-by":"crossref","first-page":"15039","DOI":"10.3390\/ijms232315039","volume":"23","author":"E Antu\u00f1a","year":"2022","unstructured":"Antu\u00f1a E, Cach\u00e1n-Vega C, Bermejo-Millo JC, Potes Y, Caballero B, Vega-Naredo I, et al. Inflammaging: implications in sarcopenia. Int J Mol Sci. 2022;23(23):15039.","journal-title":"Int J Mol Sci"},{"issue":"2","key":"1852_CR35","doi-asserted-by":"crossref","first-page":"glad238","DOI":"10.1093\/gerona\/glad238","volume":"79","author":"R Pellegrino","year":"2024","unstructured":"Pellegrino R, Paganelli R, Di Iorio A, Bandinelli S, Moretti A, Iolascon G, et al. Beyond inflammaging: the impact of immune system aging on age-related muscle decline, results from the InCHIANTI study. J Gerontol Seri A. 2024;79(2):glad238.","journal-title":"J Gerontol Seri A"},{"issue":"10","key":"1852_CR36","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.3390\/biology10101056","volume":"10","author":"A Kaczmarek","year":"2021","unstructured":"Kaczmarek A, Kaczmarek M, Cia\u0142owicz M, Clemente FM, Wola\u0144ski P, Badicu G, et al. The role of satellite cells in skeletal muscle regeneration\u2014the effect of exercise and age. Biology. 2021;10(10):1056.","journal-title":"Biology"},{"issue":"24","key":"1852_CR37","doi-asserted-by":"crossref","first-page":"17168","DOI":"10.3390\/ijms242417168","volume":"24","author":"FA Monsalve","year":"2023","unstructured":"Monsalve FA, Delgado-L\u00f3pez F, Fern\u00e1ndez-Tapia B, Gonz\u00e1lez DR. Adipose tissue, non-communicable diseases, and physical exercise: an imperfect triangle. Int J Mol Sci. 2023;24(24):17168.","journal-title":"Int J Mol Sci"},{"issue":"1","key":"1852_CR38","first-page":"1","volume":"5","author":"M Chan","year":"2025","unstructured":"Chan M, Sardar S, Rahim M, Wang M, Nalapko Y. Neuromuscular and muscular-skeletal modulations as the antiaging strategy of physical adaptation in non-communicable diseases. J Neurol Sci Res. 2025;5(1):1\u201326.","journal-title":"J Neurol Sci Res"},{"issue":"4","key":"1852_CR39","doi-asserted-by":"crossref","first-page":"588","DOI":"10.3390\/antiox10040588","volume":"10","author":"HW Hyatt","year":"2021","unstructured":"Hyatt HW, Powers SK. Mitochondrial dysfunction is a common denominator linking skeletal muscle wasting due to disease, aging, and prolonged inactivity. Antioxidants. 2021;10(4):588.","journal-title":"Antioxidants"},{"issue":"19","key":"1852_CR40","doi-asserted-by":"crossref","first-page":"e15447","DOI":"10.14814\/phy2.15447","volume":"10","author":"M Kawanishi","year":"2022","unstructured":"Kawanishi M, Kami K, Nishimura Y, Minami K, Senba E, Umemoto Y, et al. Exercise-induced increase in M2 macrophages accelerates wound healing in young mice. Physiol Rep. 2022;10(19):e15447.","journal-title":"Physiol Rep"},{"key":"1852_CR41","doi-asserted-by":"crossref","first-page":"1061353","DOI":"10.3389\/fphys.2023.1061353","volume":"14","author":"IO Callegari","year":"2023","unstructured":"Callegari IO, Rocha GZ, Oliveira AG. Physical exercise, health, and disease treatment: the role of macrophages. Front Physiol. 2023;14:1061353.","journal-title":"Front Physiol"},{"key":"1852_CR42","unstructured":"Kawanishi N, Yano H, Yokogawa Y, Suzuki K. Exercise training inhibits inflammation in adipose tissue via both suppression of macrophage infiltration and acceleration of phenotypic switching from M1 to M2 macrophages in high-fat-diet-induced obese mice. Exerc Immunol Rev. 2010;16."},{"issue":"7","key":"1852_CR43","doi-asserted-by":"crossref","first-page":"3069","DOI":"10.3390\/ijms26073069","volume":"26","author":"X Wen","year":"2025","unstructured":"Wen X, Fan J, Duan X, Zhu X, Bai J, Zhang T. Mitochondrial DNA in exercise-mediated innate immune responses. Int J Mol Sci. 2025;26(7):3069.","journal-title":"Int J Mol Sci"},{"key":"1852_CR44","first-page":"1721727X2211349","volume":"20","author":"Z Ge","year":"2022","unstructured":"Ge Z, Zhang Z, Ding S. Effects of acute endurance exercise and exhaustive exercise on innate immune signals induced by mtDNA. Eur J Inflamm. 2022;20:1721727X221134942.","journal-title":"Eur J Inflamm"},{"issue":"8","key":"1852_CR45","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1007\/s40279-023-01839-8","volume":"53","author":"L Boyd","year":"2023","unstructured":"Boyd L, Deakin GB, Devantier-Thomas B, Singh U, Doma K. The effects of pre-conditioning on exercise-induced muscle damage: a systematic review and meta-analysis. Sports Med. 2023;53(8):1537\u201357.","journal-title":"Sports Med"},{"issue":"7","key":"1852_CR46","doi-asserted-by":"crossref","first-page":"2862","DOI":"10.1002\/jcp.30723","volume":"237","author":"P Baumert","year":"2022","unstructured":"Baumert P, Cocks M, Strauss JA, Shepherd SO, Drust B, Lake MJ, et al. Polygenic mechanisms underpinning the response to exercise-induced muscle damage in humans: in vivo and in vitro evidence. J Cell Physiol. 2022;237(7):2862\u201376.","journal-title":"J Cell Physiol"},{"key":"1852_CR47","doi-asserted-by":"crossref","first-page":"723931","DOI":"10.3389\/fphys.2021.723931","volume":"12","author":"Y Kyriakidou","year":"2021","unstructured":"Kyriakidou Y, Cooper I, Kraev I, Lange S, Elliott BT. Preliminary investigations into the effect of exercise-induced muscle damage on systemic extracellular vesicle release in trained younger and older men. Front Physiol. 2021;12:723931.","journal-title":"Front Physiol"},{"issue":"2","key":"1852_CR48","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1519\/JSC.0000000000003878","volume":"35","author":"N Romero-Parra","year":"2021","unstructured":"Romero-Parra N, Cupeiro R, Alfaro-Magallanes VM, Rael B, Rubio-Arias J\u00c1, Peinado AB, et al. Exercise-induced muscle damage during the menstrual cycle: a systematic review and meta-analysis. J Strength Cond Res. 2021;35(2):549\u201361.","journal-title":"J Strength Cond Res"},{"key":"1852_CR49","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22063265","author":"N Ziemkiewicz","year":"2021","unstructured":"Ziemkiewicz N, Hilliard G, Pullen NA, Garg K. The role of innate and adaptive immune cells in skeletal muscle regeneration. Int J Mol Sci. 2021. https:\/\/doi.org\/10.3390\/ijms22063265.","journal-title":"Int J Mol Sci"},{"issue":"2","key":"1852_CR50","doi-asserted-by":"crossref","first-page":"305","DOI":"10.3390\/physiologia3020022","volume":"3","author":"AG Gakis","year":"2023","unstructured":"Gakis AG, Nomikos T, Philippou A, Antonopoulou S. The involvement of lipid mediators in the mechanisms of exercise-induced muscle damage. Physiologia. 2023;3(2):305\u201328.","journal-title":"Physiologia"},{"issue":"1","key":"1852_CR51","doi-asserted-by":"crossref","first-page":"36","DOI":"10.3390\/biomedicines9010036","volume":"9","author":"S Methenitis","year":"2021","unstructured":"Methenitis S, Stergiou I, Antonopoulou S, Nomikos T. Can exercise-induced muscle damage be a good model for the investigation of the anti-inflammatory properties of diet in humans? Biomedicines. 2021;9(1):36.","journal-title":"Biomedicines"},{"key":"1852_CR52","unstructured":"Rawlins M. Pre-mobilisation of neutrophils from acute exercise-induced: Stellenbosch University; 2023."},{"key":"1852_CR53","first-page":"101699","volume":"38","author":"JY Park","year":"2024","unstructured":"Park JY, Kim TY, Woo SW, Moon HY. Effect of exercise-induced neutrophil maturation on skeletal muscle repair in vitro. Biochem Biophys Rep. 2024;38:101699.","journal-title":"Biochem Biophys Rep"},{"key":"1852_CR54","unstructured":"Rawlins M. Pre-mobilisation of neutrophils from acute exercise-induced muscle damage: potential implications for short-term vaccination responses, satellite cell dynamics and skeletal muscle recovery: Stellenbosch: Stellenbosch University; 2023."},{"issue":"10","key":"1852_CR55","doi-asserted-by":"crossref","first-page":"127","DOI":"10.3390\/antiox7100127","volume":"7","author":"T Kawamura","year":"2018","unstructured":"Kawamura T, Suzuki K, Takahashi M, Tomari M, Hara R, Gando Y, et al. Involvement of neutrophil dynamics and function in exercise-induced muscle damage and delayed-onset muscle soreness: effect of hydrogen bath. Antioxidants. 2018;7(10):127.","journal-title":"Antioxidants"},{"issue":"5","key":"1852_CR56","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1249\/01.MSS.0000161804.05399.3B","volume":"37","author":"JM Peake","year":"2005","unstructured":"Peake JM, Suzuki K, Wilson G, Hordern M, Nosaka K, Mackinnon L, et al. Exercise-induced muscle damage, plasma cytokines, and markers of neutrophil activation. Med Sci Sports Exerc. 2005;37(5):737\u201345.","journal-title":"Med Sci Sports Exerc"},{"key":"1852_CR57","unstructured":"Kanda K, Sugama K, Hayashida H, Sakuma J, Kawakami Y, Miura S, et al. Eccentric exercise-induced delayed-onset muscle soreness and changes in markers of muscle damage and inflammation. Exerc Immunol Rev. 2013;19."},{"issue":"2","key":"1852_CR58","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1038\/icb.2015.97","volume":"94","author":"B Chazaud","year":"2016","unstructured":"Chazaud B. Inflammation during skeletal muscle regeneration and tissue remodeling: application to exercise-induced muscle damage management. Immunol Cell Biol. 2016;94(2):140\u20135.","journal-title":"Immunol Cell Biol"},{"key":"1852_CR59","doi-asserted-by":"crossref","first-page":"1133355","DOI":"10.3389\/fimmu.2023.1133355","volume":"14","author":"H Tu","year":"2023","unstructured":"Tu H, Li Y-L. Inflammation balance in skeletal muscle damage and repair. Front Immunol. 2023;14:1133355.","journal-title":"Front Immunol"},{"issue":"4","key":"1852_CR60","doi-asserted-by":"crossref","first-page":"565","DOI":"10.33549\/physiolres.934371","volume":"69","author":"A Sto\u017eer","year":"2020","unstructured":"Sto\u017eer A, Vodopivc P, Bombek LK. Pathophysiology of exercise-induced muscle damage and its structural, functional, metabolic, and clinical consequences. Physiol Res. 2020;69(4):565.","journal-title":"Physiol Res"},{"key":"1852_CR61","doi-asserted-by":"publisher","DOI":"10.2147\/JIR.S114635","author":"IG Fatouros","year":"2016","unstructured":"Fatouros IG, Jamurtas AZ. Insights into the molecular etiology of exercise-induced inflammation: opportunities for optimizing performance. J Inflamm Res. 2016. https:\/\/doi.org\/10.2147\/JIR.S114635.","journal-title":"J Inflamm Res"},{"issue":"122","key":"1852_CR62","first-page":"10-23937","volume":"5","author":"K Suzuki","year":"2019","unstructured":"Suzuki K. Characterization of exercise-induced cytokine release, the impacts on the body, the mechanisms and modulations. Int J Sports Exerc Med. 2019;5(122):10\u201323937.","journal-title":"Int J Sports Exerc Med"},{"key":"1852_CR63","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines9010036","author":"S Methenitis","year":"2021","unstructured":"Methenitis S, Stergiou I, Antonopoulou S, Nomikos T. Can exercise-induced muscle damage be a good model for the investigation of the anti-inflammatory properties of diet in humans? Biomedicines. 2021. https:\/\/doi.org\/10.3390\/biomedicines9010036.","journal-title":"Biomedicines"},{"issue":"9","key":"1852_CR64","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.1007\/s00421-016-3411-1","volume":"116","author":"P Baumert","year":"2016","unstructured":"Baumert P, Lake MJ, Stewart CE, Drust B, Erskine RM. Genetic variation and exercise-induced muscle damage: implications for athletic performance, injury and ageing. Eur J Appl Physiol. 2016;116(9):1595\u2013625.","journal-title":"Eur J Appl Physiol"},{"issue":"1","key":"1852_CR65","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1186\/s13102-024-00890-w","volume":"16","author":"GL Allsopp","year":"2024","unstructured":"Allsopp GL, Addinsall AB, Stephenson G, Basheer F, Gatta PAD, Hoffmann SM, et al. The chronic leukocyte and inflammatory cytokine responses of older adults to resistance training in normobaric hypoxia; a randomized controlled trial. BMC Sports Sci Med Rehabil. 2024;16(1):102.","journal-title":"BMC Sports Sci Med Rehabil"},{"key":"1852_CR66","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.biomaterials.2016.11.021","volume":"117","author":"CL San Emeterio","year":"2017","unstructured":"San Emeterio CL, Olingy CE, Chu Y, Botchwey EA. Selective recruitment of non-classical monocytes promotes skeletal muscle repair. Biomaterials. 2017;117:32\u201343.","journal-title":"Biomaterials"},{"issue":"17","key":"1852_CR67","doi-asserted-by":"crossref","first-page":"4118","DOI":"10.1111\/febs.12166","volume":"280","author":"M Saclier","year":"2013","unstructured":"Saclier M, Cuvellier S, Magnan M, Mounier R, Chazaud B. Monocyte\/macrophage interactions with myogenic precursor cells during skeletal muscle regeneration. FEBS J. 2013;280(17):4118\u201330.","journal-title":"FEBS J"},{"issue":"11","key":"1852_CR68","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1093\/intimm\/dxy054","volume":"30","author":"Y Oishi","year":"2018","unstructured":"Oishi Y, Manabe I. Macrophages in inflammation, repair and regeneration. Int Immunol. 2018;30(11):511\u201328.","journal-title":"Int Immunol"},{"key":"1852_CR69","doi-asserted-by":"crossref","first-page":"e14053","DOI":"10.7717\/peerj.14053","volume":"10","author":"Y Yu","year":"2022","unstructured":"Yu Y, Yue Z, Xu M, Zhang M, Shen X, Ma Z, et al. Macrophages play a key role in tissue repair and regeneration. PeerJ. 2022;10:e14053.","journal-title":"PeerJ"},{"key":"1852_CR70","doi-asserted-by":"crossref","first-page":"1113214","DOI":"10.3389\/fimmu.2023.1113214","volume":"14","author":"J Torres-Ruiz","year":"2023","unstructured":"Torres-Ruiz J, Alcal\u00e1-Carmona B, Alejandre-Aguilar R, G\u00f3mez-Mart\u00edn D. Inflammatory myopathies and beyond: the dual role of neutrophils in muscle damage and regeneration. Front Immunol. 2023;14:1113214.","journal-title":"Front Immunol"},{"key":"1852_CR71","doi-asserted-by":"crossref","first-page":"1037090","DOI":"10.3389\/fphys.2022.1037090","volume":"13","author":"Y Dong","year":"2022","unstructured":"Dong Y, Zhang X, Miao R, Cao W, Wei H, Jiang W, et al. Branched-chain amino acids promotes the repair of exercise-induced muscle damage via enhancing macrophage polarization. Front Physiol. 2022;13:1037090.","journal-title":"Front Physiol"},{"key":"1852_CR72","doi-asserted-by":"publisher","DOI":"10.5960\/dzsm.2019.390","author":"S Gehlert","year":"2019","unstructured":"Gehlert S, Jacko D. The role of the immune system in response to muscle damage. Dtsch Z Sportmed. 2019. https:\/\/doi.org\/10.5960\/dzsm.2019.390.","journal-title":"Dtsch Z Sportmed"},{"issue":"3","key":"1852_CR73","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1101\/gad.294348.116","volume":"31","author":"X Guo","year":"2017","unstructured":"Guo X, Zhao Y, Yan H, Yang Y, Shen S, Dai X, et al. Single tumor-initiating cells evade immune clearance by recruiting type II macrophages. Genes Dev. 2017;31(3):247\u201359.","journal-title":"Genes Dev"},{"key":"1852_CR74","doi-asserted-by":"crossref","first-page":"173090","DOI":"10.1016\/j.ejphar.2020.173090","volume":"877","author":"C Yunna","year":"2020","unstructured":"Yunna C, Mengru H, Lei W, Weidong C. Macrophage M1\/M2 polarization. Eur J Pharmacol. 2020;877:173090.","journal-title":"Eur J Pharmacol"},{"issue":"1","key":"1852_CR75","doi-asserted-by":"crossref","first-page":"816460","DOI":"10.1155\/2015\/816460","volume":"2015","author":"T R\u0151szer","year":"2015","unstructured":"R\u0151szer T. Understanding the mysterious M2 macrophage through activation markers and effector mechanisms. Med Inflamm. 2015;2015(1):816460.","journal-title":"Med Inflamm"},{"issue":"11","key":"1852_CR76","doi-asserted-by":"crossref","first-page":"1762","DOI":"10.4252\/wjsc.v13.i11.1762","volume":"13","author":"Z-W Luo","year":"2021","unstructured":"Luo Z-W, Sun Y-Y, Lin J-R, Qi B-J, Chen J-W. Exosomes derived from inflammatory myoblasts promote M1 polarization and break the balance of myoblast proliferation\/differentiation. World J Stem Cells. 2021;13(11):1762.","journal-title":"World J Stem Cells"},{"issue":"34","key":"1852_CR77","doi-asserted-by":"crossref","first-page":"2201957","DOI":"10.1002\/smll.202201957","volume":"18","author":"Z Luo","year":"2022","unstructured":"Luo Z, Qi B, Sun Y, Chen Y, Lin J, Qin H, et al. Engineering bioactive M2 macrophage-polarized, anti-inflammatory, miRNA-based liposomes for functional muscle repair: from exosomal mechanisms to biomaterials. Small. 2022;18(34):2201957.","journal-title":"Small"},{"key":"1852_CR78","volume-title":"Macrophage regulation of angiogenesis in health and disease. Seminars in cell & developmental biology","year":"2021","unstructured":"Martin P, Gurevich DB, editors. Macrophage regulation of angiogenesis in health and disease. Seminars in cell & developmental biology. Amsterdam: Elsevier; 2021."},{"key":"1852_CR79","doi-asserted-by":"crossref","first-page":"120667","DOI":"10.1016\/j.biomaterials.2021.120667","volume":"269","author":"CE Witherel","year":"2021","unstructured":"Witherel CE, Sao K, Brisson BK, Han B, Volk SW, Petrie RJ, et al. Regulation of extracellular matrix assembly and structure by hybrid M1\/M2 macrophages. Biomaterials. 2021;269:120667.","journal-title":"Biomaterials"},{"issue":"46","key":"1852_CR80","doi-asserted-by":"crossref","first-page":"eabi8602","DOI":"10.1126\/sciadv.abi8602","volume":"7","author":"JT Noe","year":"2021","unstructured":"Noe JT, Rendon BE, Geller AE, Conroy LR, Morrissey SM, Young LE, et al. Lactate supports a metabolic-epigenetic link in macrophage polarization. Sci Adv. 2021;7(46):eabi8602.","journal-title":"Sci Adv"},{"issue":"1","key":"1852_CR81","first-page":"5530541","volume":"2021","author":"J Zhang","year":"2021","unstructured":"Zhang J, Huang F, Chen L, Li G, Lei W, Zhao J, et al. Sodium lactate accelerates M2 macrophage polarization and improves cardiac function after myocardial infarction in mice. Cardiovasc Ther. 2021;2021(1):5530541.","journal-title":"Cardiovasc Ther"},{"issue":"3","key":"1852_CR82","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1002\/path.4301","volume":"232","author":"ML Novak","year":"2014","unstructured":"Novak ML, Weinheimer-Haus EM, Koh TJ. Macrophage activation and skeletal muscle healing following traumatic injury. J Pathol. 2014;232(3):344\u201355.","journal-title":"J Pathol"},{"issue":"19","key":"1852_CR83","doi-asserted-by":"crossref","first-page":"e15480","DOI":"10.14814\/phy2.15480","volume":"10","author":"C Bernard","year":"2022","unstructured":"Bernard C, Zavoriti A, Pucelle Q, Chazaud B, Gondin J. Role of macrophages during skeletal muscle regeneration and hypertrophy\u2014implications for immunomodulatory strategies. Physiol Rep. 2022;10(19):e15480.","journal-title":"Physiol Rep"},{"issue":"1","key":"1852_CR84","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/s40141-023-00381-y","volume":"11","author":"LS Bateman","year":"2023","unstructured":"Bateman LS, McSwain RT, Lott T, Brown TM, Cemenja SL, Jenkins JM, et al. Effects of ibuprofen on muscle hypertrophy and inflammation: a review of literature. Curr Phys Med Rehabil Rep. 2023;11(1):43\u201350.","journal-title":"Curr Phys Med Rehabil Rep"},{"key":"1852_CR85","doi-asserted-by":"crossref","first-page":"1744","DOI":"10.1007\/s00586-018-5652-7","volume":"27","author":"G James","year":"2018","unstructured":"James G, Sluka KA, Blomster L, Hall L, Schmid AB, Shu CC, et al. Macrophage polarization contributes to local inflammation and structural change in the multifidus muscle after intervertebral disc injury. Eur Spine J. 2018;27:1744\u201356.","journal-title":"Eur Spine J"},{"issue":"6","key":"1852_CR86","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1111\/nan.12730","volume":"47","author":"H K\u00f6lbel","year":"2021","unstructured":"K\u00f6lbel H, Preu\u00dfe C, Brand L, von Moers A, Della Marina A, Schuelke M, et al. Inflammation, fibrosis and skeletal muscle regeneration in LGMDR9 are orchestrated by macrophages. Neuropathol Appl Neurobiol. 2021;47(6):856\u201366.","journal-title":"Neuropathol Appl Neurobiol"},{"key":"1852_CR87","doi-asserted-by":"crossref","unstructured":"Silveira LS, Antunes BdMM, Minari ALA, Dos Santos RVT, Neto JCR, Lira FS. Macrophage polarization: implications on metabolic diseases and the role of exercise. Crit Rev\u2122 Eukaryot Gene Expr. 2016;26(2).","DOI":"10.1615\/CritRevEukaryotGeneExpr.2016015920"},{"key":"1852_CR88","doi-asserted-by":"crossref","first-page":"1037090","DOI":"10.3389\/fphys.2022.1037090","volume":"13","author":"Y Dong","year":"2022","unstructured":"Dong Y, Zhang X, Miao R, Cao W, Wei H, Jiang W, et al. Branched-chain amino acids promotes the repair of exercise-induced muscle damage via enhancing macrophage polarization. Front Physiol. 2022;13:1037090.","journal-title":"Front Physiol"},{"issue":"5","key":"1852_CR89","doi-asserted-by":"crossref","first-page":"E453","DOI":"10.1152\/ajpendo.00553.2012","volume":"304","author":"NJ Pillon","year":"2013","unstructured":"Pillon NJ, Bilan PJ, Fink LN, Klip A. Cross-talk between skeletal muscle and immune cells: muscle-derived mediators and metabolic implications. Am J Physiol Endocrinol Metab. 2013;304(5):E453\u201365.","journal-title":"Am J Physiol Endocrinol Metab"},{"issue":"19","key":"1852_CR90","doi-asserted-by":"crossref","first-page":"10393","DOI":"10.3390\/ijms251910393","volume":"25","author":"F Hernandez-Torres","year":"2024","unstructured":"Hernandez-Torres F, Matias-Valiente L, Alzas-Gomez V, Aranega AE. Macrophages in the context of muscle regeneration and Duchenne muscular dystrophy. Int J Mol Sci. 2024;25(19):10393.","journal-title":"Int J Mol Sci"},{"key":"1852_CR91","doi-asserted-by":"crossref","first-page":"2993","DOI":"10.3389\/fimmu.2019.02993","volume":"10","author":"A Batista-Gonzalez","year":"2019","unstructured":"Batista-Gonzalez A, Vidal R, Criollo A, Carre\u00f1o LJ. New insights on the role of lipid metabolism in the metabolic reprogramming of macrophages. Front Immunol. 2019;10:2993.","journal-title":"Front Immunol"},{"key":"1852_CR92","doi-asserted-by":"crossref","first-page":"1462","DOI":"10.3389\/fimmu.2019.01462","volume":"10","author":"A Viola","year":"2019","unstructured":"Viola A, Munari F, S\u00e1nchez-Rodr\u00edguez R, Scolaro T, Castegna A. The metabolic signature of macrophage responses. Front Immunol. 2019;10:1462.","journal-title":"Front Immunol"},{"issue":"1","key":"1852_CR93","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1038\/s41392-023-01452-1","volume":"8","author":"S Chen","year":"2023","unstructured":"Chen S, Saeed AFUH, Liu Q, Jiang Q, Xu H, Xiao GG, et al. Macrophages in immunoregulation and therapeutics. Signal Transduct Target Ther. 2023;8(1):207.","journal-title":"Signal Transduct Target Ther"},{"issue":"1","key":"1852_CR94","doi-asserted-by":"crossref","first-page":"101348","DOI":"10.1016\/j.xcrm.2023.101348","volume":"5","author":"L Dollet","year":"2024","unstructured":"Dollet L, Lundell LS, Chibalin AV, Pendergrast LA, Pillon NJ, Lansbury EL, et al. Exercise-induced crosstalk between immune cells and adipocytes in humans: role of oncostatin-M. Cell Rep Med. 2024;5(1):101348.","journal-title":"Cell Rep Med"},{"issue":"4","key":"1852_CR95","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1111\/febs.13827","volume":"284","author":"S Schiaffino","year":"2017","unstructured":"Schiaffino S, Pereira MG, Ciciliot S, Rovere-Querini P. Regulatory t cells and skeletal muscle regeneration. FEBS J. 2017;284(4):517\u201324.","journal-title":"FEBS J"},{"issue":"10","key":"1852_CR96","doi-asserted-by":"crossref","first-page":"5149","DOI":"10.4049\/jimmunol.1303486","volume":"193","author":"J Zhang","year":"2014","unstructured":"Zhang J, Xiao Z, Qu C, Cui W, Wang X, Du J. CD8 T cells are involved in skeletal muscle regeneration through facilitating MCP-1 secretion and Gr1high macrophage infiltration. J Immunol. 2014;193(10):5149\u201360.","journal-title":"J Immunol"},{"issue":"6","key":"1852_CR97","doi-asserted-by":"crossref","first-page":"817","DOI":"10.3390\/biom12060817","volume":"12","author":"JF Gama","year":"2022","unstructured":"Gama JF, Romualdo RD, de Assis ML, de Oliveira LM, Qu\u00edrico-Santos T, Alves LA, et al. Role of regulatory T cells in skeletal muscle regeneration: a systematic review. Biomolecules. 2022;12(6):817.","journal-title":"Biomolecules"},{"key":"1852_CR98","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.freeradbiomed.2024.09.047","volume":"225","author":"M Calvo-Rubio","year":"2024","unstructured":"Calvo-Rubio M, Garcia-Dominguez E, Tamayo-Torres E, Soto-Rodr\u00edguez S, Olaso-Gonzalez G, Ferrucci L, et al. The repeated bout effect evokes the training-induced skeletal muscle cellular memory. Free Radic Biol Med. 2024;225:247\u201354.","journal-title":"Free Radic Biol Med"},{"issue":"258","key":"1852_CR99","doi-asserted-by":"crossref","first-page":"258ra142","DOI":"10.1126\/scitranslmed.3009925","volume":"6","author":"SA Villalta","year":"2014","unstructured":"Villalta SA, Rosenthal W, Martinez L, Kaur A, Sparwasser T, Tidball JG, et al. Regulatory T cells suppress muscle inflammation and injury in muscular dystrophy. Sci Transl Med. 2014;6(258):258ra142.","journal-title":"Sci Transl Med"},{"issue":"5","key":"1852_CR100","doi-asserted-by":"crossref","first-page":"R1173","DOI":"10.1152\/ajpregu.00735.2009","volume":"298","author":"JG Tidball","year":"2010","unstructured":"Tidball JG, Villalta SA. Regulatory interactions between muscle and the immune system during muscle regeneration. Am J Physiol-Regul Integr Comp Physiol. 2010;298(5):R1173\u201387.","journal-title":"Am J Physiol-Regul Integr Comp Physiol"},{"issue":"10","key":"1852_CR101","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1016\/j.cmet.2023.08.010","volume":"35","author":"M Becker","year":"2023","unstructured":"Becker M, Joseph SS, Garcia-Carrizo F, Tom RZ, Opaleva D, Serr I, et al. Regulatory T cells require IL6 receptor alpha signaling to control skeletal muscle function and regeneration. Cell Metab. 2023;35(10):1736\u201351.","journal-title":"Cell Metab"},{"key":"1852_CR102","doi-asserted-by":"crossref","unstructured":"Jones B, Hoyne G. The role of the innate and adaptive immunity in exercise induced muscle damage and repair. J Clin Cell Immunol. 2017;8(1).","DOI":"10.4172\/2155-9899.1000482"},{"issue":"1","key":"1852_CR103","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1249\/JES.0000000000000095","volume":"45","author":"RD Hyldahl","year":"2017","unstructured":"Hyldahl RD, Chen TC, Nosaka K. Mechanisms and mediators of the skeletal muscle repeated bout effect. Exerc Sport Sci Rev. 2017;45(1):24\u201333.","journal-title":"Exerc Sport Sci Rev"},{"issue":"6","key":"1852_CR104","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1249\/MSS.0000000000002256","volume":"52","author":"MR Deyhle","year":"2020","unstructured":"Deyhle MR, Carlisle M, Sorensen JR, Hafen PS, Jesperson K, Ahmadi M, et al. Accumulation of skeletal muscle T cells and the repeated bout effect in rats. Med Sci Sports Exerc. 2020;52(6):1280\u201393.","journal-title":"Med Sci Sports Exerc"},{"issue":"1","key":"1852_CR105","doi-asserted-by":"crossref","first-page":"R222","DOI":"10.1152\/ajpregu.1996.271.1.R222","volume":"271","author":"HB Nielsen","year":"1996","unstructured":"Nielsen HB, Secher NH, Christensen NJ, Pedersen BK. Lymphocytes and NK cell activity during repeated bouts of maximal exercise. Am J Physiol-Regul Integr Comp Physiol. 1996;271(1):R222\u20137.","journal-title":"Am J Physiol-Regul Integr Comp Physiol"},{"issue":"2","key":"1852_CR106","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1615\/CritRevEukaryotGeneExpr.2016015920","volume":"26","author":"LS Silveira","year":"2016","unstructured":"Silveira LS, Antunes Bde M, Minari AL, Dos Santos RV, Neto JC, Lira FS. Macrophage polarization: implications on metabolic diseases and the role of exercise. Crit Rev Eukaryot Gene Expr. 2016;26(2):115\u201332.","journal-title":"Crit Rev Eukaryot Gene Expr"},{"issue":"9","key":"1852_CR107","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1038\/s41585-021-00476-y","volume":"18","author":"J-S Kim","year":"2021","unstructured":"Kim J-S, Galv\u00e3o DA, Newton RU, Gray E, Taaffe DR. Exercise-induced myokines and their effect on prostate cancer. Nat Rev Urol. 2021;18(9):519\u201342.","journal-title":"Nat Rev Urol"},{"key":"1852_CR108","doi-asserted-by":"crossref","first-page":"981577","DOI":"10.3389\/fphys.2022.981577","volume":"13","author":"C Qi","year":"2022","unstructured":"Qi C, Song X, Wang H, Yan Y, Liu B. The role of exercise-induced myokines in promoting angiogenesis. Front Physiol. 2022;13:981577.","journal-title":"Front Physiol"},{"issue":"3","key":"1852_CR109","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1152\/japplphysiol.00971.2016","volume":"122","author":"JM Peake","year":"2017","unstructured":"Peake JM, Neubauer O, Della Gatta PA, Nosaka K. Muscle damage and inflammation during recovery from exercise. J Appl Physiol. 2017;122(3):559\u201370.","journal-title":"J Appl Physiol"},{"issue":"1","key":"1852_CR110","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1186\/s13075-022-02846-2","volume":"24","author":"T Yamada","year":"2022","unstructured":"Yamada T, Ashida Y, Tamai K, Kimura I, Yamauchi N, Naito A, et al. Improved skeletal muscle fatigue resistance in experimental autoimmune myositis mice following high-intensity interval training. Arthritis Res Ther. 2022;24(1):156.","journal-title":"Arthritis Res Ther"},{"key":"1852_CR111","unstructured":"Gazzerro E. Role of extracellular ATP in the progression of muscle damage in sarcoglycanopathies; 2021."},{"issue":"1","key":"1852_CR112","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1146\/annurev-physiol-060721-095517","volume":"84","author":"HR Spaulding","year":"2022","unstructured":"Spaulding HR, Yan Z. AMPK and the adaptation to exercise. Annu Rev Physiol. 2022;84(1):209\u201327.","journal-title":"Annu Rev Physiol"},{"issue":"1","key":"1852_CR113","volume":"7","author":"H Chen","year":"2022","unstructured":"Chen H, Chen C, Spanos M, Li G, Lu R, Bei Y, et al. Exercise training maintains cardiovascular health: signaling pathways involved and potential therapeutics. Signal Transduct Target Ther. 2022;7(1): 306.","journal-title":"Signal Transduct Target Ther"},{"issue":"25","key":"1852_CR114","doi-asserted-by":"crossref","first-page":"20773","DOI":"10.18632\/oncotarget.4770","volume":"6","author":"L Tao","year":"2015","unstructured":"Tao L, Bei Y, Zhang H, Xiao J, Li X. Exercise for the heart: signaling pathways. Oncotarget. 2015;6(25):20773.","journal-title":"Oncotarget"},{"issue":"1","key":"1852_CR115","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1002\/cbf.1365","volume":"25","author":"EM Silveira","year":"2007","unstructured":"Silveira EM, Rodrigues MF, Krause MS, Vianna DR, Almeida BS, Rossato JS, et al. Acute exercise stimulates macrophage function: possible role of NF-\u03baB pathways. Cell Biochem Funct. 2007;25(1):63\u201373.","journal-title":"Cell Biochem Funct"},{"issue":"2","key":"1852_CR116","doi-asserted-by":"crossref","first-page":"e0318107","DOI":"10.1371\/journal.pone.0318107","volume":"20","author":"G de Azambuja","year":"2025","unstructured":"de Azambuja G, Moreira Simabuco F, Gon\u00e7alves de Oliveira MC. Macrophage-P2X4 receptors pathway is essential to persistent inflammatory muscle hyperalgesia onset, and is prevented by physical exercise. PLOS ONE. 2025;20(2):e0318107.","journal-title":"PLOS ONE"},{"key":"1852_CR117","doi-asserted-by":"crossref","first-page":"40789","DOI":"10.1038\/srep40789","volume":"7","author":"R Furrer","year":"2017","unstructured":"Furrer R, Eisele PS, Schmidt A, Beer M, Handschin C. Paracrine cross-talk between skeletal muscle and macrophages in exercise by PGC-1\u03b1-controlled BNP. Sci Rep. 2017;7:40789.","journal-title":"Sci Rep"},{"issue":"3","key":"1852_CR118","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1016\/j.bbrc.2015.06.166","volume":"464","author":"PS Eisele","year":"2015","unstructured":"Eisele PS, Furrer R, Beer M, Handschin C. The PGC-1 coactivators promote an anti-inflammatory environment in skeletal muscle in vivo. Biochem Biophys Res Commun. 2015;464(3):692\u20137.","journal-title":"Biochem Biophys Res Commun"},{"issue":"7203","key":"1852_CR119","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1038\/nature07206","volume":"454","author":"C Handschin","year":"2008","unstructured":"Handschin C, Spiegelman BM. The role of exercise and PGC1alpha in inflammation and chronic disease. Nature. 2008;454(7203):463\u20139.","journal-title":"Nature"},{"issue":"1","key":"1852_CR120","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1111\/sms.14241","volume":"33","author":"D Nash","year":"2023","unstructured":"Nash D, Hughes MG, Butcher L, Aicheler R, Smith P, Cullen T, et al. IL-6 signaling in acute exercise and chronic training: potential consequences for health and athletic performance. Scand J Med Sci Sports. 2023;33(1):4\u201319.","journal-title":"Scand J Med Sci Sports"},{"issue":"18","key":"1852_CR121","doi-asserted-by":"crossref","first-page":"2419","DOI":"10.2174\/1389557522666220309161245","volume":"22","author":"\u00c1N de Melo Madureira","year":"2022","unstructured":"de Melo Madureira \u00c1N, de Oliveira JRS, de Menezes Lima VL. The role of IL-6 released during exercise to insulin sensitivity and muscle hypertrophy. Mini Rev Med Chem. 2022;22(18):2419\u201328.","journal-title":"Mini Rev Med Chem"},{"issue":"2","key":"1852_CR122","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1038\/s42255-022-00538-4","volume":"4","author":"TM Kistner","year":"2022","unstructured":"Kistner TM, Pedersen BK, Lieberman DE. Interleukin 6 as an energy allocator in muscle tissue. Nat Metab. 2022;4(2):170\u20139.","journal-title":"Nat Metab"},{"key":"1852_CR123","doi-asserted-by":"crossref","first-page":"1117092","DOI":"10.3389\/fimmu.2023.1117092","volume":"14","author":"J Lee","year":"2023","unstructured":"Lee J, Lee K, Bae H, Lee K, Lee S, Ma J, et al. IL-15 promotes self-renewal of progenitor exhausted CD8 T cells during persistent antigenic stimulation. Front Immunol. 2023;14:1117092.","journal-title":"Front Immunol"},{"key":"1852_CR124","doi-asserted-by":"crossref","first-page":"e12296","DOI":"10.1590\/1414-431x2023e12296","volume":"56","author":"Z Wang","year":"2023","unstructured":"Wang Z, Cui Y, Zhang Y, Wang X, Li J, Li J, et al. Twelve-week treadmill endurance training in mice is associated with upregulation of interleukin-15 and natural killer cell activation and increases apoptosis rate in Hepa1-6 cell-derived mouse hepatomas. Braz J Med Biol Res. 2023;56:e12296.","journal-title":"Braz J Med Biol Res"},{"issue":"7","key":"1852_CR125","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1016\/j.ccell.2022.05.006","volume":"40","author":"E Kurz","year":"2022","unstructured":"Kurz E, Hirsch CA, Dalton T, Shadaloey SA, Khodadadi-Jamayran A, Miller G, et al. Exercise-induced engagement of the IL-15\/IL-15R\u03b1 axis promotes anti-tumor immunity in pancreatic cancer. Cancer Cell. 2022;40(7):720\u201337.","journal-title":"Cancer Cell"},{"key":"1852_CR126","doi-asserted-by":"crossref","unstructured":"Ringleb M, Javelle F, Haunhorst S, Bloch W, Fennen L, Baumgart S, et al. Acute resistance exercise-induced changes in IL-6, IL-10, and IL-1ra in healthy adults: a systematic review and meta-analysis. medRxiv. 2023:2023.05. 10.23289790.","DOI":"10.1101\/2023.05.10.23289790"},{"issue":"1","key":"1852_CR127","doi-asserted-by":"crossref","first-page":"160","DOI":"10.3390\/cells11010160","volume":"11","author":"J Bilski","year":"2022","unstructured":"Bilski J, Pierzchalski P, Szczepanik M, Bonior J, Zoladz JA. Multifactorial mechanism of sarcopenia and sarcopenic obesity. Role of physical exercise, microbiota and myokines. Cells. 2022;11(1):160.","journal-title":"Cells"},{"issue":"1","key":"1852_CR128","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1186\/s12979-024-00458-9","volume":"21","author":"N Zhang","year":"2024","unstructured":"Zhang N, Zhai L, Wong RMY, Cui C, Law SW, Chow SK, et al. Harnessing immunomodulation to combat sarcopenia: current insights and possible approaches. Immun Ageing. 2024;21(1):55.","journal-title":"Immun Ageing"},{"issue":"299","key":"1852_CR129","doi-asserted-by":"crossref","first-page":"299rv4","DOI":"10.1126\/scitranslmed.aaa7322","volume":"7","author":"AS Rosenberg","year":"2015","unstructured":"Rosenberg AS, Puig M, Nagaraju K, Hoffman EP, Villalta SA, Rao VA, et al. Immune-mediated pathology in Duchenne muscular dystrophy. Sci Transl Med. 2015;7(299):299rv4-rv4.","journal-title":"Sci Transl Med"},{"issue":"10","key":"1852_CR130","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.3390\/biomedicines9101447","volume":"9","author":"L Tripodi","year":"2021","unstructured":"Tripodi L, Villa C, Molinaro D, Torrente Y, Farini A. The immune system in Duchenne muscular dystrophy pathogenesis. Biomedicines. 2021;9(10):1447.","journal-title":"Biomedicines"},{"key":"1852_CR131","unstructured":"Proschinger S, Winker M, Joisten N, Bloch W, Palmowski J, Zimmer P. The effect of exercise on regulatory T cells: a systematic review of human and animal studies with future perspectives and methodological recommendations. Exerc Immunol Rev. 2021;27."},{"key":"1852_CR132","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1007\/s12265-018-9794-0","volume":"11","author":"Z Chen","year":"2018","unstructured":"Chen Z, Yan W, Mao Y, Ni Y, Zhou L, Song H, et al. Effect of aerobic exercise on Treg and Th17 of rats with ischemic cardiomyopathy. J Cardiovasc Transl Res. 2018;11:230\u20135.","journal-title":"J Cardiovasc Transl Res"},{"issue":"1","key":"1852_CR133","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1038\/s41572-021-00321-x","volume":"7","author":"IE Lundberg","year":"2021","unstructured":"Lundberg IE, Fujimoto M, Vencovsky J, Aggarwal R, Holmqvist M, Christopher-Stine L, et al. Idiopathic inflammatory myopathies. Nat Rev Dis Primers. 2021;7(1):86.","journal-title":"Nat Rev Dis Primers"},{"key":"1852_CR134","doi-asserted-by":"crossref","first-page":"666879","DOI":"10.3389\/fimmu.2021.666879","volume":"12","author":"A Farini","year":"2021","unstructured":"Farini A, Villa C, Tripodi L, Legato M, Torrente Y. Role of immunoglobulins in muscular dystrophies and inflammatory myopathies. Front Immunol. 2021;12:666879.","journal-title":"Front Immunol"},{"issue":"5","key":"1852_CR135","doi-asserted-by":"crossref","first-page":"103308","DOI":"10.1016\/j.autrev.2023.103308","volume":"22","author":"MG Danieli","year":"2023","unstructured":"Danieli MG, Antonelli E, Piga MA, Cozzi MF, Allegra A, Gangemi S. Oxidative stress, mitochondrial dysfunction, and respiratory chain enzyme defects in inflammatory myopathies. Autoimmun Rev. 2023;22(5):103308.","journal-title":"Autoimmun Rev"},{"key":"1852_CR136","doi-asserted-by":"publisher","DOI":"10.2147\/JIR.S377102","author":"K Lodin","year":"2024","unstructured":"Lodin K, Espinosa-Ortega F, Lundberg IE, Alexanderson H. The role of exercise to improve physiological, physical and psychological health outcome in idiopathic inflammatory myopathies (IIM). J Inflamm Res. 2024. https:\/\/doi.org\/10.2147\/JIR.S377102.","journal-title":"J Inflamm Res"},{"issue":"7","key":"1852_CR137","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1111\/1756-185X.14104","volume":"24","author":"I Coskun Benlidayi","year":"2021","unstructured":"Coskun Benlidayi I, Gupta L. The pathophysiological effects of exercise in the management of idiopathic inflammatory myopathies: a scoping review. Int J Rheum Dis. 2021;24(7):896\u2013903.","journal-title":"Int J Rheum Dis"},{"issue":"36","key":"1852_CR138","doi-asserted-by":"crossref","first-page":"eabo3192","DOI":"10.1126\/sciadv.abo3192","volume":"8","author":"NJ Pillon","year":"2022","unstructured":"Pillon NJ, Smith JA, Alm PS, Chibalin AV, Alhusen J, Arner E, et al. Distinctive exercise-induced inflammatory response and exerkine induction in skeletal muscle of people with type 2 diabetes. Sci Adv. 2022;8(36):eabo3192.","journal-title":"Sci Adv"},{"issue":"24","key":"1852_CR139","doi-asserted-by":"crossref","first-page":"13258","DOI":"10.3390\/ijerph182413258","volume":"18","author":"P Gonzalo-Encabo","year":"2021","unstructured":"Gonzalo-Encabo P, Maldonado G, Valad\u00e9s D, Ferragut C, P\u00e9rez-L\u00f3pez A. The role of exercise training on low-grade systemic inflammation in adults with overweight and obesity: a systematic review. Int J Environ Res Public Health. 2021;18(24):13258.","journal-title":"Int J Environ Res Public Health"},{"issue":"2","key":"1852_CR140","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1038\/s41366-024-01649-6","volume":"49","author":"C Chen","year":"2025","unstructured":"Chen C, Zhang D, Ye M, You Y, Song Y, Chen X. Effects of various exercise types on inflammatory response in individuals with overweight and obesity: a systematic review and network meta-analysis of randomized controlled trials. Int J Obes. 2025;49(2):214\u201325.","journal-title":"Int J Obes"},{"issue":"2","key":"1852_CR141","doi-asserted-by":"crossref","first-page":"350","DOI":"10.3390\/antiox11020350","volume":"11","author":"M Daniela","year":"2022","unstructured":"Daniela M, Catalina L, Ilie O, Paula M, Daniel-Andrei I, Ioana B. Effects of exercise training on the autonomic nervous system with a focus on anti-inflammatory and antioxidants effects. Antioxidants. 2022;11(2):350.","journal-title":"Antioxidants"},{"issue":"4","key":"1852_CR142","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.jsams.2020.10.004","volume":"24","author":"GL Rose","year":"2021","unstructured":"Rose GL, Skinner TL, Mielke GI, Schaumberg MA. The effect of exercise intensity on chronic inflammation: a systematic review and meta-analysis. J Sci Med Sport. 2021;24(4):345\u201351.","journal-title":"J Sci Med Sport"},{"issue":"10","key":"1852_CR143","doi-asserted-by":"crossref","first-page":"250","DOI":"10.5960\/dzsm.2019.391","volume":"70","author":"K Alack","year":"2019","unstructured":"Alack K, Pilat C, Kr\u00fcger K. Current knowledge and new challenges in exercise immunology. Dtsch Z Sportmed. 2019;70(10):250\u201360.","journal-title":"Dtsch Z Sportmed"},{"issue":"12","key":"1852_CR144","doi-asserted-by":"crossref","first-page":"2395","DOI":"10.1097\/HJH.0000000000002962","volume":"39","author":"MN Moore","year":"2021","unstructured":"Moore MN, Climie RE, Otahal P, Schultz MG. Exercise blood pressure and cardiovascular disease risk: a systematic review and meta-analysis of cross-sectional studies. J Hypertens. 2021;39(12):2395\u2013402.","journal-title":"J Hypertens"},{"issue":"3","key":"1852_CR145","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.jshs.2018.09.009","volume":"8","author":"DC Nieman","year":"2019","unstructured":"Nieman DC, Wentz LM. The compelling link between physical activity and the body\u2019s defense system. J Sport Health Sci. 2019;8(3):201\u201317.","journal-title":"J Sport Health Sci"},{"issue":"4","key":"1852_CR146","doi-asserted-by":"crossref","first-page":"907","DOI":"10.4161\/hv.23365","volume":"9","author":"KM Edwards","year":"2013","unstructured":"Edwards KM, Booy R. Effects of exercise on vaccine-induced immune responses. Hum Vaccin Immunother. 2013;9(4):907\u201310.","journal-title":"Hum Vaccin Immunother"},{"issue":"1","key":"1852_CR147","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/s10238-020-00650-3","volume":"21","author":"MP da Silveira","year":"2021","unstructured":"da Silveira MP, da Silva Fagundes KK, Bizuti MR, Starck \u00c9, Rossi RC, de Resende ESDT. Physical exercise as a tool to help the immune system against COVID-19: an integrative review of the current literature. Clin Exp Med. 2021;21(1):15\u201328.","journal-title":"Clin Exp Med"},{"issue":"1","key":"1852_CR148","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/s13102-022-00397-2","volume":"14","author":"S Docherty","year":"2022","unstructured":"Docherty S, Harley R, McAuley JJ, Crowe LAN, Pedret C, Kirwan PD, et al. The effect of exercise on cytokines: implications for musculoskeletal health: a narrative review. BMC Sports Sci Med Rehabil. 2022;14(1):5.","journal-title":"BMC Sports Sci Med Rehabil"},{"issue":"1","key":"1852_CR149","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.smhs.2019.08.006","volume":"1","author":"E Anderson","year":"2019","unstructured":"Anderson E, Durstine JL. Physical activity, exercise, and chronic diseases: a brief review. Sports Med Health Sci. 2019;1(1):3\u201310.","journal-title":"Sports Med Health Sci"},{"key":"1852_CR150","doi-asserted-by":"crossref","first-page":"100126","DOI":"10.1016\/j.ynpai.2023.100126","volume":"13","author":"JB Lesnak","year":"2023","unstructured":"Lesnak JB, Berardi G, Sluka KA. Influence of routine exercise on the peripheral immune system to prevent and alleviate pain. Neurobiol Pain. 2023;13:100126.","journal-title":"Neurobiol Pain"},{"issue":"1","key":"1852_CR151","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/1465-9921-14-32","volume":"14","author":"PB van de Weert-van Leeuwen","year":"2013","unstructured":"van de Weert-van Leeuwen PB, Arets HG, van der Ent CK, Beekman JM. Infection, inflammation and exercise in cystic fibrosis. Respir Res. 2013;14(1):32.","journal-title":"Respir Res"},{"key":"1852_CR152","doi-asserted-by":"crossref","first-page":"102058","DOI":"10.1016\/j.molmet.2024.102058","volume":"90","author":"Y Voskoboynik","year":"2024","unstructured":"Voskoboynik Y, McCulloch AD, Sahoo D. Macrophages on the run: exercise balances macrophage polarization for improved health. Mol Metab. 2024;90:102058.","journal-title":"Mol Metab"},{"key":"1852_CR153","doi-asserted-by":"publisher","DOI":"10.3390\/cells12091214","author":"CY Cui","year":"2023","unstructured":"Cui CY, Ferrucci L, Gorospe M. Macrophage involvement in aging-associated skeletal muscle regeneration. Cells. 2023. https:\/\/doi.org\/10.3390\/cells12091214.","journal-title":"Cells"},{"key":"1852_CR154","doi-asserted-by":"publisher","DOI":"10.3390\/ijms251910393","author":"F Hernandez-Torres","year":"2024","unstructured":"Hernandez-Torres F, Matias-Valiente L, Alzas-Gomez V, Aranega AE. Macrophages in the context of muscle regeneration and Duchenne muscular dystrophy. Int J Mol Sci. 2024. https:\/\/doi.org\/10.3390\/ijms251910393.","journal-title":"Int J Mol Sci"},{"issue":"5","key":"1852_CR155","doi-asserted-by":"crossref","first-page":"83","DOI":"10.21315\/mjms2024.31.5.6","volume":"31","author":"NSN Zaid","year":"2024","unstructured":"Zaid NSN, Muhamad AS, Jawis MN, Ooi FK, Mohamed M, Mohamud R, et al. The effect of exercise on immune response in population with increased risk factors for cardiovascular disease: a systematic review. Malays J Med Sci. 2024;31(5):83\u2013108.","journal-title":"Malays J Med Sci"},{"key":"1852_CR156","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23094636","author":"R Balakrishnan","year":"2022","unstructured":"Balakrishnan R, Thurmond DC. Mechanisms by which skeletal muscle myokines ameliorate insulin resistance. Int J Mol Sci. 2022. https:\/\/doi.org\/10.3390\/ijms23094636.","journal-title":"Int J Mol Sci"},{"key":"1852_CR157","doi-asserted-by":"publisher","DOI":"10.3390\/biom14101205","author":"Z Lu","year":"2024","unstructured":"Lu Z, Wang Z, Zhang XA, Ning K. Myokines may be the answer to the beneficial immunomodulation of tailored exercise-a narrative review. Biomolecules. 2024. https:\/\/doi.org\/10.3390\/biom14101205.","journal-title":"Biomolecules"},{"key":"1852_CR158","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00971.2016","author":"JM Peake","year":"2017","unstructured":"Peake JM, Neubauer O, Della Gatta PA, Nosaka K. Muscle damage and inflammation during recovery from exercise. J Appl Physiol. 2017. https:\/\/doi.org\/10.1152\/japplphysiol.00971.2016.","journal-title":"J Appl Physiol"},{"key":"1852_CR159","first-page":"424","volume":"6","author":"MR Deyhle","year":"2015","unstructured":"Deyhle MR, Gier AM, Evans KC, Eggett DL, Nelson WB, Parcell AC, et al. Skeletal muscle inflammation following repeated bouts of lengthening contractions in humans. Front Physiol. 2015;6:424.","journal-title":"Front Physiol"},{"key":"1852_CR160","doi-asserted-by":"crossref","first-page":"424","DOI":"10.3389\/fphys.2015.00424","volume":"6","author":"MR Deyhle","year":"2016","unstructured":"Deyhle MR, Gier AM, Evens KC, Eggett DL, Nelson WB, Parcell AC, et al. Skeletal muscle inflammation following repeated bouts of lengthening contractions in humans. Front Physiol. 2016;6:424.","journal-title":"Front Physiol"},{"issue":"7","key":"1852_CR161","doi-asserted-by":"crossref","first-page":"e001872","DOI":"10.1136\/jitc-2020-001872","volume":"9","author":"MP Gustafson","year":"2021","unstructured":"Gustafson MP, Wheatley-Guy CM, Rosenthal AC, Gastineau DA, Katsanis E, Johnson BD, et al. Exercise and the immune system: taking steps to improve responses to cancer immunotherapy. J Immunother Cancer. 2021;9(7):e001872.","journal-title":"J Immunother Cancer"},{"key":"1852_CR162","doi-asserted-by":"crossref","first-page":"836999","DOI":"10.3389\/fimmu.2022.836999","volume":"13","author":"JM Murphy","year":"2022","unstructured":"Murphy JM, Ngai L, Mortha A, Crome SQ. Tissue-dependent adaptations and functions of innate lymphoid cells. Front Immunol. 2022;13:836999.","journal-title":"Front Immunol"},{"issue":"1","key":"1852_CR163","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1038\/s41392-024-02050-5","volume":"10","author":"J Li","year":"2025","unstructured":"Li J, Xiao C, Li C, He J. Tissue-resident immune cells: from defining characteristics to roles in diseases. Signal Transduct Target Ther. 2025;10(1):12.","journal-title":"Signal Transduct Target Ther"},{"issue":"6284","key":"1852_CR164","doi-asserted-by":"crossref","first-page":"aaf1098","DOI":"10.1126\/science.aaf1098","volume":"352","author":"MG Netea","year":"2016","unstructured":"Netea MG, Joosten LA, Latz E, Mills KH, Natoli G, Stunnenberg HG, et al. Trained immunity: a program of innate immune memory in health and disease. Science. 2016;352(6284):aaf1098.","journal-title":"Science"},{"key":"1852_CR165","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.coviro.2016.11.011","volume":"22","author":"PC Rosato","year":"2017","unstructured":"Rosato PC, Beura LK, Masopust D. Tissue resident memory T cells and viral immunity. Curr Opin Virol. 2017;22:44\u201350.","journal-title":"Curr Opin Virol"},{"issue":"22","key":"1852_CR166","doi-asserted-by":"crossref","first-page":"5918","DOI":"10.1182\/blood-2011-03-340281","volume":"118","author":"RS Scotland","year":"2011","unstructured":"Scotland RS, Stables MJ, Madalli S, Watson P, Gilroy DW. Sex differences in resident immune cell phenotype underlie more efficient acute inflammatory responses in female mice. Blood. 2011;118(22):5918\u201327.","journal-title":"Blood"},{"issue":"3","key":"1852_CR167","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/j.bj.2020.02.005","volume":"44","author":"J Arag\u00f3n-Vela","year":"2021","unstructured":"Arag\u00f3n-Vela J, Fontana L, Casuso RA, Plaza-D\u00edaz J, Huertas JR. Differential inflammatory response of men and women subjected to an acute resistance exercise. Biomed J. 2021;44(3):338\u201345.","journal-title":"Biomed J"},{"issue":"5","key":"1852_CR168","doi-asserted-by":"crossref","first-page":"R581","DOI":"10.1152\/ajpregu.00010.2025","volume":"328","author":"JB Ducharme","year":"2025","unstructured":"Ducharme JB, Specht JW, Bailly AR, Deyhle MR. Serum cytokines and their soluble receptors are differently regulated between trained and untrained men after vigorous endurance exercise. Am J Physiol Regul Integr Comp Physiol. 2025;328(5):R581-r7.","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"1852_CR169","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.freeradbiomed.2024.07.026","volume":"223","author":"R Furrer","year":"2024","unstructured":"Furrer R, Handschin C. Molecular aspects of the exercise response and training adaptation in skeletal muscle. Free Radical Biol Med. 2024;223:53\u201368.","journal-title":"Free Radical Biol Med"},{"issue":"6","key":"1852_CR170","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.1016\/j.cell.2018.10.022","volume":"175","author":"BJ Schmiedel","year":"2018","unstructured":"Schmiedel BJ, Singh D, Madrigal A, Valdovino-Gonzalez AG, White BM, Zapardiel-Gonzalo J, et al. Impact of genetic polymorphisms on human immune cell gene expression. Cell. 2018;175(6):1701-15.e16.","journal-title":"Cell"},{"issue":"1","key":"1852_CR171","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1186\/s12985-024-02597-3","volume":"21","author":"JQ Yip","year":"2024","unstructured":"Yip JQ, Oo A, Ng YL, Chin KL, Tan KK, Chu JJH, et al. The role of inflammatory gene polymorphisms in severe COVID-19: a review. Virol J. 2024;21(1):327.","journal-title":"Virol J"}],"container-title":["Clinical and Experimental Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10238-025-01852-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10238-025-01852-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10238-025-01852-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T06:47:33Z","timestamp":1764917253000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10238-025-01852-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,27]]},"references-count":171,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["1852"],"URL":"https:\/\/doi.org\/10.1007\/s10238-025-01852-3","relation":{},"ISSN":["1591-9528"],"issn-type":[{"value":"1591-9528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,27]]},"assertion":[{"value":"8 June 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 August 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 August 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"Not applicable.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Clinical trial number"}}],"article-number":"306"}}