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To date, the meaning of angiogenesis in primary cutaneous lymphomas has not been fully clarified, with most data coming from T cell lymphomas, in particular mycosis fungoides. Herein, we provide a comprehensive review about their significance in both primary cutaneous T cell and B cell lymphomas, with the aim to deepen the underlying molecular mechanism and role in tumor development and progression.<\/jats:p>","DOI":"10.1007\/s10238-025-01853-2","type":"journal-article","created":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T06:50:26Z","timestamp":1761893426000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Angiogenesis and lymphangiogenesis in primary cutaneous lymphomas: a narrative review"],"prefix":"10.1007","volume":"25","author":[{"given":"Mario Della","family":"Mura","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joana","family":"Sorino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerardo","family":"Cazzato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Ingravallo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessio","family":"Giubellino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Domenico","family":"Ribatti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,10,31]]},"reference":[{"key":"1853_CR1","unstructured":"The 2018 update of the WHO-EORTC classification for primary cutaneous lymphomas."},{"key":"1853_CR2","unstructured":"WHO Classification of Tumours Editorial Board. 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