{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:29:37Z","timestamp":1786980577534,"version":"build-2736575974"},"reference-count":40,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T00:00:00Z","timestamp":1764028800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T00:00:00Z","timestamp":1764028800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Exp Med"],"DOI":"10.1007\/s10238-025-01969-5","type":"journal-article","created":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T05:13:59Z","timestamp":1764047639000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Endoscopic ultrasound elastography in solid pancreatic lesions: individual and combined performance of strain ratio, fat-lesion strain ratio, and mean strain histogram for diagnosing pancreatic ductal adenocarcinoma"],"prefix":"10.1007","volume":"26","author":[{"given":"Fangzhou","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haonan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cancan","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Hao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuai","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaoxing","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruiqi","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengyuan","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zheng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weikun","family":"Qian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zheng","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,11,25]]},"reference":[{"key":"1969_CR1","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1038\/s41575-021-00457-x","volume":"18","author":"AP Klein","year":"2021","unstructured":"Klein AP. Pancreatic cancer epidemiology: understanding the role of lifestyle and inherited risk factors. Nat Rev Gastroenterol Hepatol. 2021;18:493\u2013502. https:\/\/doi.org\/10.1038\/s41575-021-00457-x.","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"1969_CR2","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1016\/S0140-6736(10)62307-0","volume":"378","author":"A Vincent","year":"2011","unstructured":"Vincent A, Herman J, Schulick R, Hruban RH, Goggins M. Pancreatic cancer. Lancet. 2011;378:607\u201320. https:\/\/doi.org\/10.1016\/S0140-6736(10)62307-0.","journal-title":"Lancet"},{"key":"1969_CR3","doi-asserted-by":"publisher","DOI":"10.1186\/s12943-020-01169-7","volume":"19","author":"C Qin","year":"2020","unstructured":"Qin C, et al. Metabolism of pancreatic cancer: paving the way to better anticancer strategies. Mol Cancer. 2020;19:50. https:\/\/doi.org\/10.1186\/s12943-020-01169-7.","journal-title":"Mol Cancer"},{"key":"1969_CR4","doi-asserted-by":"publisher","first-page":"752","DOI":"10.1053\/j.gastro.2023.02.012","volume":"164","author":"EM Stoffel","year":"2023","unstructured":"Stoffel EM, Brand RE, Goggins M. Pancreatic cancer: changing epidemiology and new approaches to risk assessment, early detection, and prevention. Gastroenterology. 2023;164:752\u201365. https:\/\/doi.org\/10.1053\/j.gastro.2023.02.012.","journal-title":"Gastroenterology"},{"key":"1969_CR5","doi-asserted-by":"publisher","first-page":"591","DOI":"10.1055\/a-1811-7025","volume":"54","author":"P Pimentel-Nunes","year":"2022","unstructured":"Pimentel-Nunes P, et al. Endoscopic submucosal dissection for superficial gastrointestinal lesions: European society of gastrointestinal endoscopy (ESGE) guideline - update 2022. Endoscopy. 2022;54:591\u2013622. https:\/\/doi.org\/10.1055\/a-1811-7025.","journal-title":"Endoscopy"},{"issue":"4","key":"1969_CR6","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD010213.pub2","volume":"2017","author":"LM Best","year":"2017","unstructured":"Best LM, Rawji V, Pereira SP, Davidson BR, Gurusamy KS. Imaging modalities for characterising focal pancreatic lesions. Cochrane Database Syst Rev. 2017;(4):CD010213. https:\/\/doi.org\/10.1002\/14651858.CD010213.pub2.","journal-title":"Cochrane Database Syst Rev"},{"key":"1969_CR7","doi-asserted-by":"publisher","first-page":"786","DOI":"10.1016\/j.gie.2024.06.002","volume":"100","author":"AS Committee","year":"2024","unstructured":"Committee AS, o. P, et al. American society for Gastrointestinal endoscopy guideline on the role of endoscopy in the diagnosis and management of solid pancreatic masses: summary and recommendations. Gastrointest Endosc. 2024;100:786\u201396. https:\/\/doi.org\/10.1016\/j.gie.2024.06.002.","journal-title":"Gastrointest Endosc"},{"key":"1969_CR8","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1055\/a-2524-2596","volume":"57","author":"A Facciorusso","year":"2025","unstructured":"Facciorusso A, et al. Endoscopic ultrasound-guided tissue sampling: European society of gastrointestinal endoscopy (ESGE) technical and technology review. Endoscopy. 2025;57:390\u2013418. https:\/\/doi.org\/10.1055\/a-2524-2596.","journal-title":"Endoscopy"},{"key":"1969_CR9","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1016\/j.pan.2021.11.008","volume":"22","author":"M Gorris","year":"2022","unstructured":"Gorris M, et al. Sensitivity of CT, MRI, and EUS-FNA\/B in the preoperative workup of histologically proven left-sided pancreatic lesions. Pancreatology. 2022;22:136\u201341. https:\/\/doi.org\/10.1016\/j.pan.2021.11.008.","journal-title":"Pancreatology"},{"key":"1969_CR10","doi-asserted-by":"publisher","first-page":"1464","DOI":"10.1016\/j.gie.2017.12.031","volume":"87","author":"S Carrara","year":"2018","unstructured":"Carrara S, et al. EUS elastography (strain ratio) and fractal-based quantitative analysis for the diagnosis of solid pancreatic lesions. Gastrointest Endosc. 2018;87:1464\u201373. https:\/\/doi.org\/10.1016\/j.gie.2017.12.031.","journal-title":"Gastrointest Endosc"},{"key":"1969_CR11","doi-asserted-by":"publisher","first-page":"30","DOI":"10.4103\/2303-9027.175879","volume":"5","author":"AH Mohammad Alizadeh","year":"2016","unstructured":"Mohammad Alizadeh AH, Shahrokh S, Hadizadeh M, Padashi M, Zali MR. Diagnostic potency of EUS-guided FNA for the evaluation of pancreatic mass lesions. Endosc Ultrasound. 2016;5:30\u20134. https:\/\/doi.org\/10.4103\/2303-9027.175879.","journal-title":"Endosc Ultrasound"},{"key":"1969_CR12","doi-asserted-by":"publisher","first-page":"284","DOI":"10.4103\/eus.eus_25_20","volume":"9","author":"CF Dietrich","year":"2020","unstructured":"Dietrich CF. Do we need elastography for EUS? Endosc Ultrasound. 2020;9:284\u201390. https:\/\/doi.org\/10.4103\/eus.eus_25_20.","journal-title":"Endosc Ultrasound"},{"key":"1969_CR13","doi-asserted-by":"publisher","first-page":"574","DOI":"10.1016\/j.gie.2022.10.029","volume":"97","author":"SM Lewey","year":"2023","unstructured":"Lewey SM. Top tips in EUS elastography (with videos). Gastrointest Endosc. 2023;97:574\u201384. https:\/\/doi.org\/10.1016\/j.gie.2022.10.029.","journal-title":"Gastrointest Endosc"},{"key":"1969_CR14","doi-asserted-by":"publisher","first-page":"20","DOI":"10.14366\/usg.22103","volume":"42","author":"CM Shin","year":"2023","unstructured":"Shin CM, Villa E. The efficiency of contrast-enhanced endoscopic ultrasound (EUS) combined with EUS elastography for pancreatic cancer diagnosis: a systematic review and meta-analysis. Ultrasonography. 2023;42:20\u201330. https:\/\/doi.org\/10.14366\/usg.22103.","journal-title":"Ultrasonography"},{"key":"1969_CR15","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics13101686","author":"J Iglesias-Garcia","year":"2023","unstructured":"Iglesias-Garcia J, de la Iglesia-Garcia D, Larino-Noia J, Dominguez-Munoz JE. Endoscopic ultrasound (EUS) guided elastography. Diagnostics. 2023. https:\/\/doi.org\/10.3390\/diagnostics13101686.","journal-title":"Diagnostics"},{"key":"1969_CR16","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1097\/MPA.0000000000000758","volume":"46","author":"N Rustemovic","year":"2017","unstructured":"Rustemovic N, et al. Differentiation of pancreatic masses via endoscopic ultrasound strain ratio elastography using adjacent pancreatic tissue as the reference. Pancreas. 2017;46:347\u201351. https:\/\/doi.org\/10.1097\/MPA.0000000000000758.","journal-title":"Pancreas"},{"key":"1969_CR17","doi-asserted-by":"publisher","first-page":"1192","DOI":"10.1016\/j.pan.2024.09.011","volume":"24","author":"TS Lee","year":"2024","unstructured":"Lee TS, et al. Increased needle passes for comparable diagnostic yield in endoscopic ultrasound-guided tissue acquisition for pancreatic stiff lesions measured by elastography. Pancreatology. 2024;24:1192\u20138. https:\/\/doi.org\/10.1016\/j.pan.2024.09.011.","journal-title":"Pancreatology"},{"key":"1969_CR18","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1016\/j.gie.2024.10.064","volume":"101","author":"DL Diehl","year":"2025","unstructured":"Diehl DL, et al. Reproducibility of EUS-guided shear wave elastography for assessment of hepatic fibrosis: a prospective pilot cohort study. Gastrointest Endosc. 2025;101:659\u201362. https:\/\/doi.org\/10.1016\/j.gie.2024.10.064.","journal-title":"Gastrointest Endosc"},{"key":"1969_CR19","doi-asserted-by":"publisher","first-page":"2236","DOI":"10.1016\/j.jse.2017.08.001","volume":"26","author":"J Schmalzl","year":"2017","unstructured":"Schmalzl J, Fenwick A, Boehm D, Gilbert F. The application of ultrasound elastography in the shoulder. J Shoulder Elbow Surg. 2017;26:2236\u201346. https:\/\/doi.org\/10.1016\/j.jse.2017.08.001.","journal-title":"J Shoulder Elbow Surg"},{"key":"1969_CR20","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-21178-4","volume":"12","author":"E Ohno","year":"2022","unstructured":"Ohno E, et al. The role of EUS elastography-guided fine needle biopsy in the histological diagnosis of solid pancreatic lesions: a prospective exploratory study. Sci Rep. 2022;12:16603. https:\/\/doi.org\/10.1038\/s41598-022-21178-4.","journal-title":"Sci Rep"},{"key":"1969_CR21","doi-asserted-by":"publisher","unstructured":"Cho IR et al. Diagnostic performance of EUS-guided elastography for differential diagnosis of gallbladder polyp. Gastrointest Endosc 100, 449\u2013456 e441 (2024). https:\/\/doi.org\/10.1016\/j.gie.2024.02.015","DOI":"10.1016\/j.gie.2024.02.015"},{"key":"1969_CR22","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-36102-1","volume":"14","author":"Z Yao","year":"2023","unstructured":"Yao Z, et al. Virtual elastography ultrasound via generative adversarial network for breast cancer diagnosis. Nat Commun. 2023;14:788. https:\/\/doi.org\/10.1038\/s41467-023-36102-1.","journal-title":"Nat Commun"},{"key":"1969_CR23","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics14202329","author":"Y Abboud","year":"2024","unstructured":"Abboud Y, Gaddam S. The role of endoscopic ultrasound-guided shear wave elastography in pancreatic diseases. Diagnostics. 2024. https:\/\/doi.org\/10.3390\/diagnostics14202329.","journal-title":"Diagnostics"},{"key":"1969_CR24","doi-asserted-by":"publisher","first-page":"659","DOI":"10.5009\/gnl19170","volume":"14","author":"Y Yamashita","year":"2020","unstructured":"Yamashita Y, et al. Utility of elastography with endoscopic ultrasonography shear-wave measurement for diagnosing chronic pancreatitis. Gut Liver. 2020;14:659\u201364. https:\/\/doi.org\/10.5009\/gnl19170.","journal-title":"Gut Liver"},{"key":"1969_CR25","doi-asserted-by":"publisher","first-page":"439","DOI":"10.6004\/jnccn.2021.0017","volume":"19","author":"MA Tempero","year":"2021","unstructured":"Tempero MA, et al. Pancreatic adenocarcinoma, version 2.2021, NCCN clinical practice guidelines in oncology. J Natl Compr Canc Netw. 2021;19:439\u201357. https:\/\/doi.org\/10.6004\/jnccn.2021.0017.","journal-title":"J Natl Compr Canc Netw"},{"key":"1969_CR26","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1038\/s41575-018-0005-x","volume":"15","author":"JP Neoptolemos","year":"2018","unstructured":"Neoptolemos JP, et al. Therapeutic developments in pancreatic cancer: current and future perspectives. Nat Rev Gastroenterol Hepatol. 2018;15:333\u201348. https:\/\/doi.org\/10.1038\/s41575-018-0005-x.","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"1969_CR27","doi-asserted-by":"publisher","first-page":"603","DOI":"10.6004\/jnccn.2019.5007","volume":"17","author":"MA Tempero","year":"2019","unstructured":"Tempero MA. NCCN guidelines updates: pancreatic cancer. J Natl Compr Canc Netw. 2019;17:603\u20135. https:\/\/doi.org\/10.6004\/jnccn.2019.5007.","journal-title":"J Natl Compr Canc Netw"},{"key":"1969_CR28","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1016\/j.ejca.2015.12.026","volume":"57","author":"T Conroy","year":"2016","unstructured":"Conroy T, et al. Current standards and new innovative approaches for treatment of pancreatic cancer. Eur J Cancer. 2016;57:10\u201322. https:\/\/doi.org\/10.1016\/j.ejca.2015.12.026.","journal-title":"Eur J Cancer"},{"key":"1969_CR29","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1016\/j.gie.2018.09.002","volume":"88","author":"H El","year":"2018","unstructured":"El H, II, Al-Haddad M. Impact of preoperative EUS-guided FNA for pancreatic cancer on overall and cancer-free survival: is the jury still out? Gastrointest Endosc. 2018;88:935\u20138. https:\/\/doi.org\/10.1016\/j.gie.2018.09.002.","journal-title":"Gastrointest Endosc"},{"key":"1969_CR30","doi-asserted-by":"publisher","first-page":"5900","DOI":"10.1158\/1078-0432.CCR-21-1107","volume":"27","author":"J Lundy","year":"2021","unstructured":"Lundy J, et al. Targeted transcriptome and KRAS mutation analysis improve the diagnostic performance of EUS-FNA biopsies in pancreatic cancer. Clin Cancer Res. 2021;27:5900\u201311. https:\/\/doi.org\/10.1158\/1078-0432.CCR-21-1107.","journal-title":"Clin Cancer Res"},{"key":"1969_CR31","doi-asserted-by":"publisher","first-page":"926","DOI":"10.1016\/j.gie.2018.06.024","volume":"88","author":"SH Kim","year":"2018","unstructured":"Kim SH, et al. Preoperative EUS-guided FNA: effects on peritoneal recurrence and survival in patients with pancreatic cancer. Gastrointest Endosc. 2018;88:926\u201334. https:\/\/doi.org\/10.1016\/j.gie.2018.06.024.","journal-title":"Gastrointest Endosc"},{"key":"1969_CR32","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1016\/j.cgh.2009.07.038","volume":"7","author":"A Masamune","year":"2009","unstructured":"Masamune A, Watanabe T, Kikuta K, Shimosegawa T. Roles of pancreatic stellate cells in pancreatic inflammation and fibrosis. Clin Gastroenterol Hepatol. 2009;7:48\u201354. https:\/\/doi.org\/10.1016\/j.cgh.2009.07.038.","journal-title":"Clin Gastroenterol Hepatol"},{"key":"1969_CR33","doi-asserted-by":"publisher","first-page":"550","DOI":"10.1136\/gut.2008.154401","volume":"58","author":"A Masamune","year":"2009","unstructured":"Masamune A, et al. Fibrinogen induces cytokine and collagen production in pancreatic stellate cells. Gut. 2009;58:550\u20139. https:\/\/doi.org\/10.1136\/gut.2008.154401.","journal-title":"Gut"},{"key":"1969_CR34","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2317141121","volume":"121","author":"T Yi","year":"2024","unstructured":"Yi T, Wagner G. Malignant tumor cells engender second membrane-lined organelles for self-protection and tumor progression. Proc Natl Acad Sci U S A. 2024;121:e2317141121. https:\/\/doi.org\/10.1073\/pnas.2317141121.","journal-title":"Proc Natl Acad Sci U S A"},{"key":"1969_CR35","doi-asserted-by":"publisher","first-page":"681","DOI":"10.1038\/s41568-020-00300-6","volume":"20","author":"CA Klein","year":"2020","unstructured":"Klein CA. Cancer progression and the invisible phase of metastatic colonization. Nat Rev Cancer. 2020;20:681\u201394. https:\/\/doi.org\/10.1038\/s41568-020-00300-6.","journal-title":"Nat Rev Cancer"},{"key":"1969_CR36","doi-asserted-by":"publisher","first-page":"3712","DOI":"10.3748\/wjg.v22.i14.3712","volume":"22","author":"N Kawada","year":"2016","unstructured":"Kawada N, Tanaka S. Elastography for the pancreas: current status and future perspective. World J Gastroenterol. 2016;22:3712\u201324. https:\/\/doi.org\/10.3748\/wjg.v22.i14.3712.","journal-title":"World J Gastroenterol"},{"key":"1969_CR37","doi-asserted-by":"publisher","first-page":"1172","DOI":"10.1053\/j.gastro.2010.06.059","volume":"139","author":"J Iglesias-Garcia","year":"2010","unstructured":"Iglesias-Garcia J, Larino-Noia J, Abdulkader I, Forteza J, Dominguez-Munoz JE. Quantitative endoscopic ultrasound elastography: an accurate method for the differentiation of solid pancreatic masses. Gastroenterology. 2010;139:1172\u201380. https:\/\/doi.org\/10.1053\/j.gastro.2010.06.059.","journal-title":"Gastroenterology"},{"key":"1969_CR38","doi-asserted-by":"publisher","first-page":"953","DOI":"10.1016\/j.gie.2012.05.034","volume":"76","author":"MF Dawwas","year":"2012","unstructured":"Dawwas MF, Taha H, Leeds JS, Nayar MK, Oppong KW. Diagnostic accuracy of quantitative EUS elastography for discriminating malignant from benign solid pancreatic masses: a prospective, single-center study. Gastrointest Endosc. 2012;76:953\u201361. https:\/\/doi.org\/10.1016\/j.gie.2012.05.034.","journal-title":"Gastrointest Endosc"},{"key":"1969_CR39","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000011689","volume":"97","author":"HH Okasha","year":"2018","unstructured":"Okasha HH, et al. Endoscopic ultrasound (EUS) elastography and strain ratio, could it help in differentiating malignant from benign pancreatic lesions? Medicine (Baltimore). 2018;97:e11689. https:\/\/doi.org\/10.1097\/MD.0000000000011689.","journal-title":"Medicine (Baltimore)"},{"key":"1969_CR40","doi-asserted-by":"publisher","first-page":"360","DOI":"10.5946\/ce.2018.160","volume":"52","author":"AY Altonbary","year":"2019","unstructured":"Altonbary AY, Hakim H, El-Shamy AM. Diagnostic efficacy of endoscopic ultrasound elastography in differentiating solid pancreatic lesions: a single-center experience. Clin Endosc. 2019;52:360\u20134. https:\/\/doi.org\/10.5946\/ce.2018.160.","journal-title":"Clin Endosc"}],"container-title":["Clinical and Experimental Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10238-025-01969-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10238-025-01969-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10238-025-01969-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T05:14:00Z","timestamp":1764047640000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10238-025-01969-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,25]]},"references-count":40,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["1969"],"URL":"https:\/\/doi.org\/10.1007\/s10238-025-01969-5","relation":{},"ISSN":["1591-9528"],"issn-type":[{"value":"1591-9528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,25]]},"assertion":[{"value":"3 January 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 November 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 November 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"48"}}