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The procedures were performed in accordance with the guidelines established by the National Institutes of Health (NIH) Guide for the Care and Use of Laboratory Animals (8th Edition, 2011), ensuring humane treatment of animals and minimizing their pain and discomfort.","order":2,"name":"Ethics","label":"Ethics approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":3,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"292"}}