{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T07:08:12Z","timestamp":1789110492869,"version":"build-2803163510"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,7,26]],"date-time":"2026-07-26T00:00:00Z","timestamp":1785024000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T00:00:00Z","timestamp":1789084800000},"content-version":"vor","delay-in-days":47,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"DOI":"10.13039\/501100007128","name":"Natural Science Foundation of Shaanxi Province","doi-asserted-by":"crossref","award":["no.2024JC-YBQN-0807"],"award-info":[{"award-number":["no.2024JC-YBQN-0807"]}],"id":[{"id":"10.13039\/501100007128","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Exp Med"],"DOI":"10.1007\/s10238-026-02264-7","type":"journal-article","created":{"date-parts":[[2026,7,26]],"date-time":"2026-07-26T05:42:59Z","timestamp":1785044579000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pan-cancer analysis identifies KANSL2 as a cell-cycle\u2013associated regulator of tumor progression and immunity in liver hepatocellular carcinoma"],"prefix":"10.1007","volume":"26","author":[{"given":"Nanbin","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junqiao","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenbin","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Senyang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keping","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,26]]},"reference":[{"issue":"9","key":"2264_CR1","doi-asserted-by":"publisher","first-page":"6151","DOI":"10.1097\/JS9.0000000000002711","volume":"111","author":"Y Han","year":"2025","unstructured":"Han Y, Liu JC, Zhang YY, Li Y, Chen X, Liu BQ, et al. Sex differences in the association of planetary health diet, genetic risk, with overall cancer incidence: a prospective study from UK Biobank. Int J Surg. 2025;111(9):6151\u201361.","journal-title":"Int J Surg"},{"issue":"1","key":"2264_CR2","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1158\/1055-9965.EPI-25-1197","volume":"35","author":"HG Cheng","year":"2026","unstructured":"Cheng HG, Hong S, Palesh O, Winn RA, Martins R, Tossas KY. Multiple primary cancer incidence by county-level smoking prevalence among U.S. cancer survivors. Cancer Epidemiol Biomarkers Prev. 2026;35(1):165\u201372.","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"2264_CR3","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2025.1615492","volume":"15","author":"J Qin","year":"1973","unstructured":"Qin J, Wu M, Zhao S, Gu K, Cai R, Tang Z, et al. Trends in cancer incidence and mortality in the process of metropolitanization of Shanghai, 1973-2017. Front Oncol. 1973;15:1615492.","journal-title":"Front Oncol"},{"issue":"4","key":"2264_CR4","doi-asserted-by":"publisher","DOI":"10.3390\/cancers17040609","volume":"17","author":"P Danpanichkul","year":"2000","unstructured":"Danpanichkul P, Pang Y, Diaz LA, Arab JP, Hwang SY, Dejvajara D, et al. Young adults and alcohol-associated liver cancer: incidence and death from 2000 to 2021. Cancers (Basel). 2000;17(4):609.","journal-title":"Cancers (Basel)"},{"issue":"6","key":"2264_CR5","volume":"16","author":"D Hu","year":"2022","unstructured":"Hu D, Yu J, Feng J, Liu P, Chen JM, Zhang HL. Comparison and trend analysis of cancer incidence in China and globally in 2022. World J Clin Oncol. 2022;16(6):107016.","journal-title":"World J Clin Oncol"},{"issue":"1","key":"2264_CR6","doi-asserted-by":"publisher","DOI":"10.1186\/s12935-025-04088-z","volume":"26","author":"ED Zhang","year":"2025","unstructured":"Zhang ED, Li C, Cheng Z, Jin L, Zeng Z, Huang H. Single-cell transcriptome analysis reveals regulatory programs of prognosis-associated RNA binding proteins during LIHC development. Cancer Cell Int. 2025;26(1):6.","journal-title":"Cancer Cell Int"},{"issue":"6","key":"2264_CR7","doi-asserted-by":"publisher","DOI":"10.3390\/bios13060617","volume":"13","author":"S Park","year":"2023","unstructured":"Park S, Cho E, Chueng SD, Yoon JS, Lee T, Lee JH. Aptameric fluorescent biosensors for liver cancer diagnosis. Biosens. 2023;13(6):617.","journal-title":"Biosens"},{"key":"2264_CR8","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2024.1534723","volume":"15","author":"S Huang","year":"2025","unstructured":"Huang S, Tu T. Integrating single cell analysis and machine learning methods reveals stem cell-related gene S100A10 as an important target for prediction of liver cancer diagnosis and immunotherapy. Front Immunol. 2025;15:1534723.","journal-title":"Front Immunol"},{"issue":"9","key":"2264_CR9","doi-asserted-by":"publisher","first-page":"929","DOI":"10.1101\/gad.240200.114","volume":"28","author":"J Dias","year":"2014","unstructured":"Dias J, Van Nguyen N, Georgiev P, Gaub A, Brettschneider J, Cusack S, et al. Structural analysis of the KANSL1\/WDR5\/KANSL2 complex reveals that WDR5 is required for efficient assembly and chromatin targeting of the NSL complex. Genes Dev. 2014;28(9):929\u201342.","journal-title":"Genes Dev"},{"key":"2264_CR10","volume-title":"Practical Guide to Life Science Databases","author":"M Safran","year":"2021","unstructured":"Safran M, et al. The GeneCards Suite. In: Abugessaisa I, Kasukawa T, editors., et al., Practical Guide to Life Science Databases. Singapore: Springer; 2021."},{"issue":"7","key":"2264_CR11","doi-asserted-by":"publisher","first-page":"4268","DOI":"10.1074\/jbc.C109.087981","volume":"285","author":"Y Cai","year":"2010","unstructured":"Cai Y, Jin J, Swanson SK, Cole MD, Choi SH, Florens L, et al. Subunit composition and substrate specificity of a MOF-containing histone acetyltransferase distinct from the male-specific lethal (MSL) complex. J Biol Chem. 2010;285(7):4268\u201372.","journal-title":"J Biol Chem"},{"issue":"8","key":"2264_CR12","doi-asserted-by":"publisher","first-page":"1749","DOI":"10.1016\/j.molcel.2021.02.012","volume":"81","author":"A Radzisheuskaya","year":"2021","unstructured":"Radzisheuskaya A, Shliaha PV, Grinev VV, Shlyueva D, Damhofer H, Koche R, et al. Complex-dependent histone acetyltransferase activity of KAT8 determines its role in transcription and cellular homeostasis. Mol Cell. 2021;81(8):1749-1765.e8.","journal-title":"Mol Cell"},{"issue":"6","key":"2264_CR13","doi-asserted-by":"publisher","DOI":"10.1111\/gbb.12648","volume":"19","author":"KM Price","year":"2020","unstructured":"Price KM, Wigg KG, Feng Y, Blokland K, Wilkinson M, He G, et al. Genome-wide association study of word reading: overlap with risk genes for neurodevelopmental disorders. Genes Brain Behav. 2020;19(6):e12648.","journal-title":"Genes Brain Behav"},{"issue":"12","key":"2264_CR14","doi-asserted-by":"publisher","DOI":"10.26508\/lsa.202101205","volume":"5","author":"J Viard","year":"2022","unstructured":"Viard J, Loe-Mie Y, Daudin R, Khelfaoui M, Plancon C, Boland A, et al. Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer\u2019s disease. Life Sci Alliance. 2022;5(12):e202101205.","journal-title":"Life Sci Alliance"},{"issue":"7","key":"2264_CR15","doi-asserted-by":"publisher","first-page":"828","DOI":"10.1038\/s41556-020-0526-8","volume":"22","author":"BN Sheikh","year":"2020","unstructured":"Sheikh BN, Guhathakurta S, Tsang TH, Schwabenland M, Renschler G, Herquel B, et al. Neural metabolic imbalance induced by MOF dysfunction triggers pericyte activation and breakdown of vasculature. Nat Cell Biol. 2020;22(7):828\u201341.","journal-title":"Nat Cell Biol"},{"issue":"1","key":"2264_CR16","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-58448-y","volume":"10","author":"PO Oladimeji","year":"2020","unstructured":"Oladimeji PO, Bakke J, Wright WC, Chen T. KANSL2 and MBNL3 are regulators of pancreatic ductal adenocarcinoma invasion. Sci Rep. 2020;10(1):1485.","journal-title":"Sci Rep"},{"issue":"8","key":"2264_CR17","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-022-05146-4","volume":"13","author":"O Yedier-Bayram","year":"2022","unstructured":"Yedier-Bayram O, Gokbayrak B, Kayabolen A, Aksu AC, Cavga AD, Cing\u00f6z A, et al. EPIKOL, a chromatin-focused CRISPR\/Cas9-based screening platform, to identify cancer-specific epigenetic vulnerabilities. Cell Death Dis. 2022;13(8):710.","journal-title":"Cell Death Dis"},{"issue":"18","key":"2264_CR18","doi-asserted-by":"publisher","first-page":"5383","DOI":"10.1158\/0008-5472.CAN-15-3159","volume":"76","author":"NE Ferreyra Solari","year":"2016","unstructured":"Ferreyra Solari NE, Belforte FS, Canedo L, Videla-Richardson GA, Espinosa JM, Rossi M, et al. The NSL chromatin-modifying complex subunit KANSL2 regulates cancer stem-like properties in glioblastoma that contribute to tumorigenesis. Cancer Res. 2016;76(18):5383\u201394.","journal-title":"Cancer Res"},{"issue":"6","key":"2264_CR19","doi-asserted-by":"publisher","first-page":"1016","DOI":"10.1158\/1535-7163.MCT-25-0379","volume":"25","author":"K Jiang","year":"2025","unstructured":"Jiang K, Kirchner M, Herzberg F, Zhao Y, Gasper A, Baumgartner F, et al. The histone modifier KANSL2 is an actionable biomarker in multiple myeloma. Mol Cancer Ther. 2025;25(6):1016\u201329.","journal-title":"Mol Cancer Ther"},{"issue":"7","key":"2264_CR20","doi-asserted-by":"publisher","DOI":"10.1002\/mco2.70243","volume":"6","author":"T Wolde","year":"2020","unstructured":"Wolde T, Bhardwaj V, Pandey V. Current bioinformatics tools in precision oncology. MedComm. 2020;6(7):e70243.","journal-title":"MedComm"},{"issue":"17","key":"2264_CR21","doi-asserted-by":"publisher","first-page":"5515","DOI":"10.7150\/jca.98449","volume":"15","author":"H Qin","year":"2024","unstructured":"Qin H, Lu H, Qin C, Huang X, Peng K, Li Y, et al. Pan-cancer analysis suggests that LY6H is a potential biomarker of diagnosis, immunoinfiltration, and prognosis. J Cancer. 2024;15(17):5515\u201339.","journal-title":"J Cancer"},{"issue":"11","key":"2264_CR22","doi-asserted-by":"publisher","first-page":"7686","DOI":"10.1097\/JS9.0000000000002903","volume":"111","author":"B Zhang","year":"2025","unstructured":"Zhang B, Cho WC, Leung PC, Wong CK, Wang D. Pan-cancer multi-omics profiling of MS4A2 unveils its functional landscape in lung adenocarcinoma. Int J Surg. 2025;111(11):7686\u201397.","journal-title":"Int J Surg"},{"issue":"Pt 1","key":"2264_CR23","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2025.148136","volume":"331","author":"Z Yu","year":"2025","unstructured":"Yu Z, Hu F, Nie C, Fang X, Shen Y, Shang R, et al. Bone morphogenetic protein 1 as a macromolecular pan-cancer biomarker modulating the immune microenvironment and malignant phenotypes in glioblastoma. Int J Biol Macromol. 2025;331(Pt 1):148136.","journal-title":"Int J Biol Macromol"},{"issue":"7","key":"2264_CR24","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2024.e29098","volume":"10","author":"H Xiong","year":"2024","unstructured":"Xiong H, Chen Z, Li Y, Wu Z, Qian D, Chen L, et al. Pan-cancer analysis of the prognostic and immunological role of FKBP4. Heliyon. 2024;10(7):e29098.","journal-title":"Heliyon"},{"issue":"11","key":"2264_CR25","doi-asserted-by":"publisher","first-page":"1747","DOI":"10.1101\/gr.239244.118","volume":"28","author":"A Mayakonda","year":"2018","unstructured":"Mayakonda A, Lin DC, et al. Maftools: efficient and comprehensive analysis of somatic variants in cancer. Genome Res. 2018;28(11):1747\u201356.","journal-title":"Genome Res"},{"key":"2264_CR26","doi-asserted-by":"publisher","DOI":"10.1186\/s12935-020-01472-9","author":"F Bi","year":"2020","unstructured":"Bi F, Chen Y, Yang Q. Significance of tumor mutation burden combined with immune infiltrates in the progression and prognosis of ovarian cancer. Cancer Cell Int. 2020. https:\/\/doi.org\/10.1186\/s12935-020-01472-9.","journal-title":"Cancer Cell Int"},{"key":"2264_CR27","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2022.998336","volume":"12","author":"J Cai","year":"2022","unstructured":"Cai J, Ye Z, Hu Y, Wang Y, Ye L, Gao L, et al. FAIM2 is a potential pan-cancer biomarker for prognosis and immune infiltration. Front Oncol. 2022;12:998336.","journal-title":"Front Oncol"},{"key":"2264_CR28","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.831542","volume":"13","author":"R Chen","year":"2022","unstructured":"Chen R, Wu W, Chen SY, Liu ZZ, Wen ZP, Yu J, et al. A pan-cancer analysis reveals CLEC5A as a biomarker for cancer immunity and prognosis. Front Immunol. 2022;13:831542.","journal-title":"Front Immunol"},{"issue":"2","key":"2264_CR29","doi-asserted-by":"crossref","DOI":"10.21859\/ijb.1610","volume":"21","author":"Z Chen","year":"2023","unstructured":"Chen Z, Xiao Y, Yang P, Wang R. Pan-cancer analysis reveals SRC may link lipid metabolism and macrophages. Iran J Biotechnol. 2023;21(2):e3325.","journal-title":"Iran J Biotechnol"},{"issue":"6","key":"2264_CR30","doi-asserted-by":"publisher","DOI":"10.1016\/j.gendis.2025.101677","volume":"12","author":"C Li","year":"2025","unstructured":"Li C, Liang Z, Vontz G, Kent C, Ma W, Liu L, et al. Exploring CISD1 as a multifaceted biomarker in cancer: implications for diagnosis, prognosis, and immunotherapeutic response. Genes Dis. 2025;12(6):101677.","journal-title":"Genes Dis"},{"issue":"5","key":"2264_CR31","doi-asserted-by":"publisher","first-page":"793","DOI":"10.2174\/0115665232331353240911080642","volume":"25","author":"Y Zhang","year":"2025","unstructured":"Zhang Y, Zhao Z, Huang W, Kim BS, Lin L, Li X, et al. Pan-cancer single-cell analysis revealing the heterogeneity of cancer- associated fibroblasts in skin tumors. Curr Gene Ther. 2025;25(5):793\u2013821.","journal-title":"Curr Gene Ther"},{"issue":"1","key":"2264_CR32","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-025-09075-y","volume":"15","author":"B Bhinder","year":"2025","unstructured":"Bhinder B, Friedl V, Sethuraman S, Risso D, Chiotti KE, Mashl RJ, et al. Pan-cancer immune and stromal deconvolution predicts clinical outcomes and mutation profiles. Sci Rep. 2025;15(1):23921.","journal-title":"Sci Rep"},{"issue":"1","key":"2264_CR33","doi-asserted-by":"publisher","DOI":"10.1080\/15384047.2025.2458773","volume":"26","author":"Z Quan","year":"2025","unstructured":"Quan Z, Fan S, Zheng H, Ning Y, Yang Y. A pan-cancer analysis of MARCH8: molecular characteristics, clinical relevance, and immuno-oncology features. Cancer Biol Ther. 2025;26(1):2458773.","journal-title":"Cancer Biol Ther"},{"issue":"1","key":"2264_CR34","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1007\/s13577-021-00630-z","volume":"35","author":"C Yang","year":"2022","unstructured":"Yang C, Zhang Z, Tang X, Zhang X, Chen Y, Hu T, et al. Pan-cancer analysis reveals homologous recombination deficiency score as a predictive marker for immunotherapy responders. Hum Cell. 2022;35(1):199\u2013213.","journal-title":"Hum Cell"},{"issue":"1","key":"2264_CR35","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-025-96389-6","volume":"15","author":"X Yang","year":"2025","unstructured":"Yang X, Cao X, Zhu Q, Wu H. Pan-cancer analysis of GJB5 as a novel prognostic and immunological biomarker. Sci Rep. 2025;15(1):14879.","journal-title":"Sci Rep"},{"issue":"13","key":"2264_CR36","doi-asserted-by":"publisher","first-page":"1557761","DOI":"10.3389\/fcell.2025.1557761","volume":"31","author":"H Dong","year":"2025","unstructured":"Dong H, Tian Y, Xin S, Guo Y, Jiang S, Wan Z, et al. Pan-cancer analysis of CHRDL1 expression and its mechanistic role in inhibiting EMT via the TGF-\u03b2 pathway in lung adenocarcinoma. Front Cell Dev Biol. 2025;31(13):1557761.","journal-title":"Front Cell Dev Biol"},{"key":"2264_CR37","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkac394","author":"Y Liu","year":"2022","unstructured":"Liu Y, Yang X, Gan J, Chen S, Xiao Z-X, Cao Y. CB-Dock2: improved protein-ligand blind docking by integrating cavity detection, docking and homologous template fitting. Nucleic Acids Res. 2022. https:\/\/doi.org\/10.1093\/nar\/gkac394.","journal-title":"Nucleic Acids Res"},{"issue":"6","key":"2264_CR38","doi-asserted-by":"publisher","DOI":"10.3390\/biom13060883","volume":"13","author":"X Huang","year":"2023","unstructured":"Huang X, Tan J, Chen M, Zheng W, Zou S, Ye X, et al. Prognostic, immunological, and mutational analysis of MTA2 in pan-cancer and drug screening for hepatocellular carcinoma. Biomolecules. 2023;13(6):883.","journal-title":"Biomolecules"},{"key":"2264_CR39","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1007\/978-1-0716-3441-7_6","volume":"2714","author":"Y Liu","year":"2024","unstructured":"Liu Y, Cao Y. Protein-ligand blind docking using CB-Dock2. Methods Mol Biol. 2024;2714:113\u201325.","journal-title":"Methods Mol Biol"},{"issue":"2","key":"2264_CR40","doi-asserted-by":"publisher","DOI":"10.1016\/j.gendis.2025.101873","volume":"13","author":"W Chen","year":"2025","unstructured":"Chen W, Han L, Wang J, Song L. Ferroptosis: the dawn of reversing drug resistance in digestive cancers. Genes Dis. 2025;13(2):101873.","journal-title":"Genes Dis"},{"issue":"26","key":"2264_CR41","first-page":"00046","volume":"S2090\u20131232","author":"C Wen","year":"2026","unstructured":"Wen C, Jiao Y, Wang Z, Shi T, Wang Y, Xu J, et al. m6A methylation in ferroptosis regulation: mechanisms, targets, and therapeutic interventions. J Adv Res. 2026;S2090\u20131232(26):00046\u20139.","journal-title":"J Adv Res"},{"issue":"7","key":"2264_CR42","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2020.101302","volume":"23","author":"Z Liu","year":"2020","unstructured":"Liu Z, Zhao Q, Zuo ZX, Yuan SQ, Yu K, Zhang Q, et al. Systematic analysis of the aberrances and functional implications of ferroptosis in cancer. iScience. 2020;23(7):101302.","journal-title":"iScience"},{"issue":"1","key":"2264_CR43","doi-asserted-by":"publisher","DOI":"10.1186\/s12943-019-1066-3","volume":"18","author":"Y Li","year":"2019","unstructured":"Li Y, Xiao J, Bai J, Tian Y, Qu Y, Chen X, et al. Molecular characterization and clinical relevance of m6A regulators across 33 cancer types. Mol Cancer. 2019;18(1):137.","journal-title":"Mol Cancer"},{"key":"2264_CR44","doi-asserted-by":"publisher","DOI":"10.1186\/s12864-016-2590-9","volume":"17","author":"F S\u00fcndermann","year":"2016","unstructured":"S\u00fcndermann F, Fernandez MP, Morgan RO. An evolutionary roadmap to the microtubule-associated protein MAP tau. BMC Genomics. 2016;17:264.","journal-title":"BMC Genomics"},{"issue":"4","key":"2264_CR45","doi-asserted-by":"publisher","DOI":"10.4161\/21624054.2014.982967","volume":"3","author":"M Hoe","year":"2014","unstructured":"Hoe M, Nicholas HR. Evidence of a MOF histone acetyltransferase-containing NSL complex in C. elegans. Worm. 2014;3(4):e982967.","journal-title":"Worm"},{"issue":"5","key":"2264_CR46","doi-asserted-by":"publisher","DOI":"10.1002\/mrd.23760","volume":"91","author":"A Chander","year":"2024","unstructured":"Chander A, Mager J. Loss of KANSL3 leads to defective inner cell mass and early embryonic lethality. Mol Reprod Dev. 2024;91(5):e23760.","journal-title":"Mol Reprod Dev"},{"issue":"2","key":"2264_CR47","doi-asserted-by":"publisher","first-page":"589","DOI":"10.3892\/etm.2016.3424","volume":"12","author":"C Li","year":"2016","unstructured":"Li C, Chen M, Zhao P, Ayana DA, Wang L, Jiang Y. Expression of MCRS1 and MCRS2 and their correlation with serum carcinoembryonic antigen in colorectal cancer. Exp Ther Med. 2016;12(2):589\u201396.","journal-title":"Exp Ther Med"},{"issue":"7","key":"2264_CR48","doi-asserted-by":"publisher","first-page":"1335","DOI":"10.1158\/2767-9764.CRC-23-0036","volume":"3","author":"BJ Bulen","year":"2023","unstructured":"Bulen BJ, Khazanov NA, Hovelson DH, Lamb LE, Matrana M, Burkard ME, et al. Validation of immunotherapy response score as predictive of pan-solid tumor Anti-PD-1\/PD-L1 benefit. Cancer Res Commun. 2023;3(7):1335\u201349.","journal-title":"Cancer Res Commun"},{"issue":"2","key":"2264_CR49","doi-asserted-by":"publisher","first-page":"329","DOI":"10.3390\/cancers18020329","volume":"18","author":"IP Ganesan","year":"2026","unstructured":"Ganesan IP, Kiyokawa H. Frontiers in cell-cycle-targeting therapies: addressing the heterogeneity of the cancer cell cycle. Cancers (Basel). 2026;18(2):329.","journal-title":"Cancers (Basel)"}],"container-title":["Clinical and Experimental Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10238-026-02264-7","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10238-026-02264-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10238-026-02264-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T06:43:02Z","timestamp":1789108982000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10238-026-02264-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,26]]},"references-count":49,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["2264"],"URL":"https:\/\/doi.org\/10.1007\/s10238-026-02264-7","relation":{},"ISSN":["1591-9528"],"issn-type":[{"value":"1591-9528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,26]]},"assertion":[{"value":"15 May 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 July 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 July 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Informed consent was obtained from all subjects involved in the study. Written informed consent has been obtained from the patient(s) to publish this paper.","order":1,"name":"Ethics","label":"Informed consent","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","label":"Conflicts of interest","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"329"}}