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Subjects with esthetic demands showing multiple upper gingival recessions of at least 2\u00a0mm, without interproximal attachment loss and cervical abrasion no more than 1\u00a0mm were recruited and randomized to CAF plus CMX or CAF alone. The Smile Esthetic Index (SEI) was adopted to quantify the quality of the smile recorded at baseline and 12\u00a0months after treatment for each treatment group. In addition, between group difference in the SEI was calculated. 24 Patients were treated and analysed. At baseline, mean gingival recession depths were 2.3\u2009\u00b1\u20090.7\u00a0mm for Test group and 2.6\u2009\u00b1\u20091.0\u00a0mm for Control group. After 1\u00a0year, the residual recession depth was 0.3\u2009\u00b1\u20090.4\u00a0mm in the CAF\u2009+\u2009CMX group and 0.6\u2009\u00b1\u20090.3\u00a0mm in the control group. The SEI at baseline was 8.1\u2009\u00b1\u20091.0 and 7.9\u2009\u00b1\u20090.7 for Test and Control group, respectively. The between groups difference at 12\u00a0months in SEI was 0.4 (95% C.I.\u2009<jats:bold>\u2212\u2009<\/jats:bold>0.0 to 0.8, <jats:italic>P<\/jats:italic>\u2009=\u20090.0697). Twelve months after treatment, CAF\u2009+\u2009CMX provided a similar SEI compared to CAF alone and the adjunct of a collagen matrix did not show a different impact on the smile esthetic appearance.<\/jats:p>","DOI":"10.1007\/s10266-020-00544-6","type":"journal-article","created":{"date-parts":[[2020,8,9]],"date-time":"2020-08-09T04:02:16Z","timestamp":1596945736000},"page":"295-302","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Smile esthetic evaluation of mucogingival reconstructive surgery"],"prefix":"10.1007","volume":"109","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9090-0624","authenticated-orcid":false,"given":"Roberto","family":"Rotundo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luigi","family":"Genzano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michele","family":"Nieri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ugo","family":"Covani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Pe\u00f1arrocha-Oltra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel","family":"Pe\u00f1arrocha-Diago","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,8,9]]},"reference":[{"key":"544_CR1","unstructured":"American Academy of Cosmetic Dentistry (AACD). 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The study was self-funded by the authors.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}