{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T23:44:16Z","timestamp":1790811856866,"version":"4.1.0"},"reference-count":48,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,7,8]],"date-time":"2021-07-08T00:00:00Z","timestamp":1625702400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,7,8]],"date-time":"2021-07-08T00:00:00Z","timestamp":1625702400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Odontology"],"published-print":{"date-parts":[[2022,1]]},"DOI":"10.1007\/s10266-021-00634-z","type":"journal-article","created":{"date-parts":[[2021,7,8]],"date-time":"2021-07-08T12:05:21Z","timestamp":1625745921000},"page":"183-192","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Consecutive tooth agenesis patterns in non-syndromic oligodontia"],"prefix":"10.1007","volume":"110","author":[{"given":"Ryuichi","family":"Baba","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayaka","family":"Sato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6245-8709","authenticated-orcid":false,"given":"Kazuhito","family":"Arai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,7,8]]},"reference":[{"key":"634_CR1","doi-asserted-by":"publisher","first-page":"650","DOI":"10.1016\/S0889-5406(00)70173-9","volume":"117","author":"H Vastardis","year":"2000","unstructured":"Vastardis H. The genetics of human tooth agenesis: new discoveries for understanding dental anomalies. Am J Orthod Dentofacl Orthop. 2000;117:650\u20136.","journal-title":"Am J Orthod Dentofacl Orthop"},{"key":"634_CR2","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1007\/s00056-013-0138-z","volume":"74","author":"S Ruf","year":"2013","unstructured":"Ruf S, Klimas D, Honemann M, Jabir S. Genetic background of nonsyndromic oligodontia: a systematic review and meta-analysis. J Orofac Orthop. 2013;74:295\u2013308. https:\/\/doi.org\/10.1007\/s00056-013-0138-z.","journal-title":"J Orofac Orthop"},{"key":"634_CR3","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1016\/j.jdsr.2017.08.001","volume":"54","author":"NH Fauzi","year":"2018","unstructured":"Fauzi NH, Ardini YD, Zainuddin Z, Lestari W. A review on non-syndromic tooth agenesis associated with PAX9 mutations. Jpn Dent Sci Rev. 2018;54:30\u20136. https:\/\/doi.org\/10.1016\/j.jdsr.2017.08.001.","journal-title":"Jpn Dent Sci Rev"},{"key":"634_CR4","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1111\/ecc.12038","volume":"22","author":"S Nishimura","year":"2013","unstructured":"Nishimura S, Inada H, Sawa Y, Ishikawa H. Risk factors to cause tooth formation anomalies in chemotherapy of paediatric cancers. Eur J Cancer Care. 2013;22:353\u201360. https:\/\/doi.org\/10.1111\/ecc.12038.","journal-title":"Eur J Cancer Care"},{"key":"634_CR5","doi-asserted-by":"publisher","first-page":"1014","DOI":"10.1177\/0022034517711156","volume":"96","author":"AH Al-Ani","year":"2017","unstructured":"Al-Ani AH, Antoun JS, Thomson WM, Merriman TR, Farella M. Maternal smoking during pregnancy is associated with offspring hypodontia. J Dent Res. 2017;96:1014\u20139. https:\/\/doi.org\/10.1177\/0022034517711156.","journal-title":"J Dent Res"},{"key":"634_CR6","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1111\/clr.13033","volume":"29","author":"K Bertl","year":"2018","unstructured":"Bertl K, Bertl MH, Heimel P, Burt M, Gahleitner A, Stavropoulos A, et al. Alveolar bone resorption after primary tooth loss has a negative impact on straightforward implant installation in patients with agenesis of the lower second premolar. Clin Oral Implants Res. 2018;29:155\u201363. https:\/\/doi.org\/10.1111\/clr.13033.","journal-title":"Clin Oral Implants Res"},{"key":"634_CR7","doi-asserted-by":"publisher","first-page":"697","DOI":"10.1093\/ejo\/22.6.697","volume":"22","author":"S Robertsson","year":"2000","unstructured":"Robertsson S, Mohlin B. The congenitally missing upper lateral incisor. A retrospective study of orthodontic space closure versus restorative treatment. Eur J Orthod. 2000;22:697\u2013710. https:\/\/doi.org\/10.1093\/ejo\/22.6.697.","journal-title":"Eur J Orthod"},{"key":"634_CR8","first-page":"409","volume":"20","author":"MA Creton","year":"2007","unstructured":"Creton MA, Cune MS, Verhoeven W, Meijer GJ. Patterns of missing teeth in a population of oligodontia patients. Int J Prosthodont. 2007;20:409\u201313.","journal-title":"Int J Prosthodont"},{"key":"634_CR9","first-page":"46","volume":"38","author":"KR Mathu-Muju","year":"2016","unstructured":"Mathu-Muju KR, Kennedy DB. Loss of permanent first molars in the mixed dentition: circumstances resulting in extraction and requiring orthodontic management. Pediatr Dent. 2016;38:46\u201353.","journal-title":"Pediatr Dent"},{"key":"634_CR10","doi-asserted-by":"publisher","first-page":"1980","DOI":"10.1002\/ajmg.a.32864","volume":"149A","author":"AF Visinoni","year":"2009","unstructured":"Visinoni AF, Lisboa-Costa T, Pagnan NA, Chautard-Freire-Maia EA. Ectodermal dysplasias: clinical and molecular review. Am J Med Genet A. 2009;149A:1980\u20132002. https:\/\/doi.org\/10.1002\/ajmg.a.32864.","journal-title":"Am J Med Genet A"},{"key":"634_CR11","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1177\/154405910308200303","volume":"82","author":"AR Vieira","year":"2003","unstructured":"Vieira AR. Oral clefts and syndromic forms of tooth agenesis as models for genetics of isolated tooth agenesis. J Dent Res. 2003;82:162\u20135. https:\/\/doi.org\/10.1177\/154405910308200303.","journal-title":"J Dent Res"},{"key":"634_CR12","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1597\/12-180","volume":"51","author":"JH Reitsma","year":"2014","unstructured":"Reitsma JH, Ongkosuwito EM, van Wijk AJ, Prahl-Andersen B. Patterns of tooth agenesis in patients with Crouzon or Apert syndrome. Cleft Palate Craniofac J. 2014;51:178\u201383. https:\/\/doi.org\/10.1597\/12-180.","journal-title":"Cleft Palate Craniofac J"},{"key":"634_CR13","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1111\/j.1365-2842.1980.tb00447.x","volume":"7","author":"JA Hobkirk","year":"1980","unstructured":"Hobkirk JA, Brook AH. The management of patients with severe hypodontia. J Oral Rehabil. 1980;7:289\u201398. https:\/\/doi.org\/10.1111\/j.1365-2842.1980.tb00447.x.","journal-title":"J Oral Rehabil"},{"key":"634_CR14","first-page":"133","volume":"59","author":"Y Schalk-van der Weide","year":"1992","unstructured":"Schalk-van der Weide Y, Steen WH, Bosman F. Distribution of missing teeth and tooth morphology in patients with oligodontia. ASDC J Dent Child. 1992;59:133\u201340.","journal-title":"ASDC J Dent Child"},{"key":"634_CR15","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1093\/oxfordjournals.ejo.a035999","volume":"11","author":"PH Brook","year":"1989","unstructured":"Brook PH, Shaw WC. The development of an index of orthodontic treatment priority. Eur J Orthod. 1989;11:309\u201320. https:\/\/doi.org\/10.1093\/oxfordjournals.ejo.a035999.","journal-title":"Eur J Orthod"},{"key":"634_CR16","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1016\/j.ajodo.2018.09.015","volume":"156","author":"K Arai","year":"2019","unstructured":"Arai K. Tooth agenesis patterns in Japanese orthodontic patients with nonsyndromic oligodontia. Am J Orthod Dentofac Orthop. 2019;156:238\u201347. https:\/\/doi.org\/10.1016\/j.ajodo.2018.09.015.","journal-title":"Am J Orthod Dentofac Orthop"},{"key":"634_CR17","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1093\/ejo\/cjq046","volume":"33","author":"SP Tan","year":"2011","unstructured":"Tan SP, van Wijk AJ, Prahl-Andersen B. Severe hypodontia: identifying patterns of human tooth agenesis. Eur J Orthod. 2011;33:150\u20134. https:\/\/doi.org\/10.1093\/ejo\/cjq046.","journal-title":"Eur J Orthod"},{"key":"634_CR18","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1111\/j.1600-0528.2004.00158.x","volume":"32","author":"BJ Polder","year":"2004","unstructured":"Polder BJ, Van\u2019t Hof MA, Van der Linden FP, Kuijpers-Jagtman AM. A meta-analysis of the prevalence of dental agenesis of permanent teeth. Community Dent Oral Epidemiol. 2004;32:217\u201326. https:\/\/doi.org\/10.1111\/j.1600-0528.2004.00158.x.","journal-title":"Community Dent Oral Epidemiol"},{"key":"634_CR19","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1093\/ejo\/cjt021","volume":"36","author":"K Dreesen","year":"2014","unstructured":"Dreesen K, Swinnen S, Devriendt K, Carels C. Tooth agenesis patterns and phenotype variation in a cohort of Belgian patients with hypodontia and oligodontia clustered in 79 families with their pedigrees. Eur J Orthod. 2014;36:99\u2013106. https:\/\/doi.org\/10.1093\/ejo\/cjt021.","journal-title":"Eur J Orthod"},{"key":"634_CR20","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1111\/joor.12384","volume":"43","author":"MA Filius","year":"2016","unstructured":"Filius MA, Cune MS, Raghoebar GM, Vissink A, Visser A. Prosthetic treatment outcome in patients with severe hypodontia: a systematic review. J Oral Rehabil. 2016;43:373\u201387. https:\/\/doi.org\/10.1111\/joor.12384.","journal-title":"J Oral Rehabil"},{"key":"634_CR21","doi-asserted-by":"publisher","first-page":"886","DOI":"10.1177\/0022034515581644","volume":"94","author":"K Carter","year":"2015","unstructured":"Carter K, Worthington S. Morphologic and demographic predictors of third molar agenesis: a systematic review and meta-analysis. J Dent Res. 2015;94:886\u201394. https:\/\/doi.org\/10.1177\/0022034515581644.","journal-title":"J Dent Res"},{"key":"634_CR22","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1016\/j.ajodo.2014.05.030","volume":"147","author":"H Tomonari","year":"2015","unstructured":"Tomonari H, Yagi T, Kuninori T, Ikemori T, Miyawaki S. Replacement of a first molar and 3 second molars by the mesial inclination of 4 impacted third molars in an adult with a Class II Division 1 malocclusion. Am J Orthod Dentofac Orthop. 2015;147:755\u201365. https:\/\/doi.org\/10.1016\/j.ajodo.2014.05.030.","journal-title":"Am J Orthod Dentofac Orthop"},{"key":"634_CR23","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1038\/s41415-020-1264-9","volume":"228","author":"L Armstrong","year":"2020","unstructured":"Armstrong L, O\u2019Reilly C, Ahmed B. Autotransplantation of third molars: a literature review and preliminary protocols. Br Dent J. 2020;228:247\u201351. https:\/\/doi.org\/10.1038\/s41415-020-1264-9.","journal-title":"Br Dent J"},{"key":"634_CR24","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1111\/j.1365-2842.1991.tb00070.x","volume":"18","author":"LV Foster","year":"1991","unstructured":"Foster LV. The relationship between failure and design in conventional bridgework from general dental practice. J Oral Rehabil. 1991;18:491\u20135. https:\/\/doi.org\/10.1111\/j.1365-2842.1991.tb00070.x.","journal-title":"J Oral Rehabil"},{"issue":"Suppl 1","key":"634_CR25","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1111\/j.1365-2842.2007.01826.x","volume":"35","author":"B Thilander","year":"2008","unstructured":"Thilander B. Orthodontic space closure versus implant placement in subjects with missing teeth. J Oral Rehabil. 2008;35(Suppl 1):64\u201371. https:\/\/doi.org\/10.1111\/j.1365-2842.2007.01826.x.","journal-title":"J Oral Rehabil"},{"key":"634_CR26","doi-asserted-by":"publisher","first-page":"1048","DOI":"10.1111\/j.1600-051X.2009.01482.x","volume":"36","author":"F Van der Weijden","year":"2009","unstructured":"Van der Weijden F, Dell\u2019Acqua F, Slot DE. Alveolar bone dimensional changes of post-extraction sockets in humans: a systematic review. J Clin Periodontol. 2009;36:1048\u201358. https:\/\/doi.org\/10.1111\/j.1600-051X.2009.01482.x.","journal-title":"J Clin Periodontol"},{"key":"634_CR27","first-page":"569","volume":"20","author":"PK Moy","year":"2005","unstructured":"Moy PK, Medina D, Shetty V, Aghaloo TL. Dental implant failure rates and associated risk factors. Int J Oral Maxillofac Implants. 2005;20:569\u201377.","journal-title":"Int J Oral Maxillofac Implants"},{"key":"634_CR28","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1016\/j.archoralbio.2018.11.018","volume":"98","author":"S Heuberer","year":"2019","unstructured":"Heuberer S, Ulm C, Zechner W, Laky B, Watzak G. Patterns of congenitally missing teeth of non-syndromic and syndromic patients treated at a single-center over the past thirty years. Arch Oral Biol. 2019;98:140\u20137. https:\/\/doi.org\/10.1016\/j.archoralbio.2018.11.018.","journal-title":"Arch Oral Biol"},{"key":"634_CR29","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.archoralbio.2018.08.014","volume":"96","author":"BN Souza-Silva","year":"2018","unstructured":"Souza-Silva BN, Vieira WA, Bernardino IM, Batista MJ, Bittencourt MAV, Paranhos LR. Non-syndromic tooth agenesis patterns and their association with other dental anomalies: a retrospective study. Arch Oral Biol. 2018;96:26\u201332. https:\/\/doi.org\/10.1016\/j.archoralbio.2018.08.014.","journal-title":"Arch Oral Biol"},{"key":"634_CR30","first-page":"7","volume":"4","author":"CE Misch","year":"1987","unstructured":"Misch CE, Judy KW. Classification of partially edentulous arches for implant dentistry. Int J Oral Implantol. 1987;4:7\u201313.","journal-title":"Int J Oral Implantol"},{"key":"634_CR31","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1093\/ejo\/cjr061","volume":"34","author":"S Meaney","year":"2012","unstructured":"Meaney S, Anweigi L, Ziada H, Allen F. The impact of hypodontia: a qualitative study on the experiences of patients. Eur J Orthod. 2012;34:547\u201352. https:\/\/doi.org\/10.1093\/ejo\/cjr061.","journal-title":"Eur J Orthod"},{"key":"634_CR32","doi-asserted-by":"publisher","DOI":"10.5037\/jomr.2017.8203","volume":"8","author":"AMG Costa","year":"2017","unstructured":"Costa AMG, Trevizan M, Matsumoto MAN, da Silva RAB, da Silva LAB, Horta KC, Romano FL, Nelson-Filho P, K\u00fcchler EC. Association between tooth agenesis and skeletal malocclusions. J Oral Maxillofac Res. 2017;8: e3. https:\/\/doi.org\/10.5037\/jomr.2017.8203.","journal-title":"J Oral Maxillofac Res"},{"key":"634_CR33","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1186\/1477-7525-8-126","volume":"8","author":"AE Gerritsen","year":"2010","unstructured":"Gerritsen AE, Allen PF, Witter DJ, Bronkhorst EM, Creugers NH. Tooth loss and oral health-related quality of life: a systematic review and meta-analysis. Health Qual Life Outcomes. 2010;8:126. https:\/\/doi.org\/10.1186\/1477-7525-8-126.","journal-title":"Health Qual Life Outcomes"},{"key":"634_CR34","doi-asserted-by":"publisher","first-page":"573","DOI":"10.7326\/0003-4819-147-8-200710160-00010","volume":"147","author":"E Von Elm","year":"2007","unstructured":"Von Elm E, Altman DG, Egger M, Pocock SJ, G\u00f8tzsche PC, Vandenbroucke JP. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. Ann Intern Med. 2007;147:573\u20137.","journal-title":"Ann Intern Med"},{"key":"634_CR35","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1093\/ejo\/cjv008","volume":"38","author":"V Rakhshan","year":"2016","unstructured":"Rakhshan V, Rakhshan H. Meta-analysis and systematic review of the number of non-syndromic congenitally missing permanent teeth per affected individual and its influencing factors. Eur J Orthod. 2016;38:170\u20137. https:\/\/doi.org\/10.1093\/ejo\/cjv008.","journal-title":"Eur J Orthod"},{"key":"634_CR36","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.odw.2019.04.001","volume":"78","author":"A Sato","year":"2019","unstructured":"Sato A, Arai K. Estimation of tooth agenesis risks between tooth types in orthodontic patients with non-syndromic oligodontia. Orthod Waves. 2019;78:49\u201355. https:\/\/doi.org\/10.1016\/j.odw.2019.04.001.","journal-title":"Orthod Waves"},{"key":"634_CR37","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2021.105038","volume":"124","author":"A Sato","year":"2021","unstructured":"Sato A, Arai K. Sexual dimorphism of tooth agenesis patterns in non-syndromic oligodontia in Japanese patients. Arch Oral Biol. 2021;124: 105038. https:\/\/doi.org\/10.1016\/j.archoralbio.2021.105038.","journal-title":"Arch Oral Biol"},{"key":"634_CR38","first-page":"75","volume":"21","author":"H De Backer","year":"2008","unstructured":"De Backer H, Van Maele G, De Moor N, Van den Berghe L. Long-term results of short-span versus long-span fixed dental prostheses: an up to 20-year retrospective study. Int J Prosthodont. 2008;21:75\u201385.","journal-title":"Int J Prosthodont"},{"key":"634_CR39","doi-asserted-by":"publisher","first-page":"1306","DOI":"10.1177\/0022034518777460","volume":"97","author":"BP Fournier","year":"2018","unstructured":"Fournier BP, Bruneau MH, Toupenay S, Kerner S, Berdal A, Cormier-Daire V, Hadj-Rabia S, Coudert AE, Dure-Molla ML. Patterns of dental agenesis highlight the nature of the causative mutated genes. J Dent Res. 2018;97:1306\u201316. https:\/\/doi.org\/10.1177\/0022034518777460.","journal-title":"J Dent Res"},{"key":"634_CR40","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1177\/154405910608500312","volume":"85","author":"JW Kim","year":"2006","unstructured":"Kim JW, Simmer JP, Lin BP, Hu JC. Novel MSX1 frameshift causes autosomal-dominant oligodontia. J Dent Res. 2006;85:267\u201371. https:\/\/doi.org\/10.1177\/154405910608500312.","journal-title":"J Dent Res"},{"key":"634_CR41","doi-asserted-by":"publisher","first-page":"e22","DOI":"10.1111\/clr.12323","volume":"26","author":"S Heuberer","year":"2015","unstructured":"Heuberer S, Dvorak G, Mayer C, Watzek G, Zechner W. Dental implants are a viable alternative for compensating oligodontia in adolescents. Clin Oral Implants Res. 2015;26:e22\u20137. https:\/\/doi.org\/10.1111\/clr.12323.","journal-title":"Clin Oral Implants Res"},{"key":"634_CR42","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1111\/clr.12531","volume":"27","author":"JS Kern","year":"2016","unstructured":"Kern JS, Kern T, Wolfart S, Heussen N. A systematic review and meta-analysis of removable and fixed implant-supported prostheses in edentulous jaws: post-loading implant loss. Clin Oral Implants Res. 2016;27:174\u201395. https:\/\/doi.org\/10.1111\/clr.12531.","journal-title":"Clin Oral Implants Res"},{"key":"634_CR43","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1007\/s10266-019-00462-2","volume":"108","author":"Y Kabasawa","year":"2020","unstructured":"Kabasawa Y, Seto-Sugiki Y, Endo T. Maxillary sinus size and posterior tooth inclination in Japanese orthodontic patients with agenesis of maxillary second premolars. Odontology. 2020;108:312\u201320. https:\/\/doi.org\/10.1007\/s10266-019-00462-2.","journal-title":"Odontology"},{"key":"634_CR44","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1038\/ng0896-417","volume":"13","author":"H Vastardis","year":"1996","unstructured":"Vastardis H, Karimbux N, Guthua SW, Seidman JG, Seidman CE. A human MSX1 homeodomain missense mutation causes selective tooth agenesis. Nat Genet. 1996;13:417\u201321. https:\/\/doi.org\/10.1038\/ng0896-417.","journal-title":"Nat Genet"},{"issue":"8","key":"634_CR45","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.10367","volume":"17","author":"M Scheiwiller","year":"2020","unstructured":"Scheiwiller M, Oeschger ES, Gkantidis N. Third molar agenesis in modern humans with and without agenesis of other teeth. PeerJ. 2020;17(8): e10367. https:\/\/doi.org\/10.7717\/peerj.10367.","journal-title":"PeerJ"},{"key":"634_CR46","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1016\/s1079-2104(03)00461-x","volume":"97","author":"B Mej\u00e0re","year":"2004","unstructured":"Mej\u00e0re B, Wannfors K, Jansson L. A prospective study on transplantation of third molars with complete root formation. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004;97:231\u20138. https:\/\/doi.org\/10.1016\/s1079-2104(03)00461-x.","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"634_CR47","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1016\/j.archoralbio.2017.02.020","volume":"79","author":"N Gkantidis","year":"2017","unstructured":"Gkantidis N, Katib H, Oeschger E, Karamolegkou M, Topouzelis N, Kanavakis G. Patterns of non-syndromic permanent tooth agenesis in a large orthodontic population. Arch Oral Biol. 2017;79:42\u20137. https:\/\/doi.org\/10.1016\/j.archoralbio.2017.02.020.","journal-title":"Arch Oral Biol"},{"key":"634_CR48","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1093\/ejo\/cjz090","volume":"42","author":"CL Hvaring","year":"2019","unstructured":"Hvaring CL, Birkeland K. The long-term fate of persisting deciduous molars and canines in 42 patients with severe hypodontia: a 12-year follow-up. Eur J Orthod. 2019;42:581\u20136. https:\/\/doi.org\/10.1093\/ejo\/cjz090.","journal-title":"Eur J Orthod"}],"container-title":["Odontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10266-021-00634-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10266-021-00634-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10266-021-00634-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,5]],"date-time":"2022-01-05T22:15:48Z","timestamp":1641420948000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10266-021-00634-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,8]]},"references-count":48,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["634"],"URL":"https:\/\/doi.org\/10.1007\/s10266-021-00634-z","relation":{},"ISSN":["1618-1247","1618-1255"],"issn-type":[{"value":"1618-1247","type":"print"},{"value":"1618-1255","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7,8]]},"assertion":[{"value":"29 March 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 June 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 July 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no relevant financial or non-financial interests to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The protocol of the present study was reviewed and approved by the Ethics Committee of The Nippon Dental University, School of Life Dentistry at Tokyo (NDUH-RINRI2018-18).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"The need for informed consent from each patient was waived by the Ethics Committee because of the retrospective and observational design of this epidemiological study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}