{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:15:48Z","timestamp":1792782948838,"version":"4.5.0"},"reference-count":46,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T00:00:00Z","timestamp":1765324800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T00:00:00Z","timestamp":1765324800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Mansoura University","id":[{"id":"https:\/\/ror.org\/01k8vtd75","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Odontology"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    In implant dentistry, demineralized dentin matrix is frequently utilized as a bone substitute as it contains many growth factors. This study aimed to evaluate the clinical and radiographic outcomes of an autogenous dentin-derived barrier membrane compared with a collagen membrane for guided bone regeneration in immediate dental implant placement in the mandibular posterior region. A total of 40 implants were placed in this randomized clinical study involving 35 patients who required extraction and replacement of non-restorable mandibular premolar or molar teeth with implants. The patients were randomly divided into two equal groups. In Group I, 20 implants were placed immediately after extraction using a dentin-derived barrier membrane, while in Group II, 20 implants were placed immediately with a collagen membrane. Evaluations were performed immediately postoperatively and after 3 and 9\u00a0months to assess implant stability, Landry healing index, modified sulcus bleeding index, peri-implant pocket depth, marginal bone loss, and relative bone density. A total of 20 female patients and 15 male patients were enrolled in this study. No statistically significant differences were found between the two groups regarding implant stability, soft tissue parameters, marginal bone loss, and relative bone density at different time intervals (\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&gt;\u20090.05). The dentin-derived barrier membrane appears to be effective for successful guided bone regeneration. Therefore, in implant dentistry, it could be considered a novel, natural collagen membrane and may represent a cost-effective autogenous alternative to commercially available collagen membranes.\n                    <jats:italic>Trial registration:<\/jats:italic>\n                    This study was registered under registration number NCT06615362 on\n                    <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/www.clinicaltrials.gov\" ext-link-type=\"uri\">www.clinicaltrials.gov<\/jats:ext-link>\n                    on 26\/9\/2024.\n                  <\/jats:p>","DOI":"10.1007\/s10266-025-01271-6","type":"journal-article","created":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T16:23:35Z","timestamp":1765383815000},"page":"2109-2122","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Autogenous dentin-derived membrane as a biologic alternative to collagen membrane for guided bone regeneration in immediate implant placement in the posterior mandible: a randomized clinical trial"],"prefix":"10.1007","volume":"114","clinical-trial-number":[{"clinical-trial-number":"nct06615362","registry":"10.18810\/clinical-trials-gov"}],"author":[{"given":"El Hussein Farag Alsayed","family":"Mohamad","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sally","family":"Awad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahy Hassouna","family":"Abbas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2583-9211","authenticated-orcid":false,"given":"Heba Abo-Elfetouh","family":"Elsheikh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,12,10]]},"reference":[{"issue":"1","key":"1271_CR1","doi-asserted-by":"publisher","first-page":"18","DOI":"10.3126\/jnspoi.v3i1.24823","volume":"3","author":"B Dhami","year":"2019","unstructured":"Dhami B, Shrestha P, Gupta S, Pandey N. Immediate implant placement: current concepts. J Nepal Soc Periodontol Oral Implantol. 2019;3(1):18\u201324. https:\/\/doi.org\/10.3126\/jnspoi.v3i1.24823.","journal-title":"J Nepal Soc Periodontol Oral Implantol"},{"issue":"1","key":"1271_CR2","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1111\/prd.12167","volume":"73","author":"V Chappuis","year":"2017","unstructured":"Chappuis V, Ara\u00fajo MG, Buser D. Clinical relevance of dimensional bone and soft tissue alterations post\u2010extraction in esthetic sites. Periodontol 2000. 2017;73(1):73\u201383. https:\/\/doi.org\/10.1111\/prd.12167.","journal-title":"Periodontol 2000"},{"issue":"6","key":"1271_CR3","doi-asserted-by":"publisher","first-page":"1549","DOI":"10.3390\/jcm13061549","volume":"13","author":"M de Ara\u00fajo Nobre","year":"2024","unstructured":"de Ara\u00fajo Nobre M, Antunes C, Lopes A, Ferro A, Nunes M, Gouveia M, et al. Partial implant rehabilitations in the posterior regions of the jaws supported by short dental implants (7.0 mm): a 7-year clinical and 5-year radiographical prospective study. J Clin Med. 2024;13(6):1549. https:\/\/doi.org\/10.3390\/jcm13061549.","journal-title":"J Clin Med"},{"key":"1271_CR4","doi-asserted-by":"publisher","first-page":"2659893","DOI":"10.1155\/crid\/2659893","volume":"1","author":"T Franke","year":"2024","unstructured":"Franke T, Korzinskas T. Guided bone regeneration in the posterior mandible using a resorbable metal magnesium membrane and fixation screws: a case report. Case Rep Dent. 2024;1:2659893. https:\/\/doi.org\/10.1155\/crid\/2659893.","journal-title":"Case Rep Dent"},{"issue":"3","key":"1271_CR5","doi-asserted-by":"publisher","first-page":"e13488","DOI":"10.1016\/j.heliyon.2023.e13488","volume":"9","author":"S Patil","year":"2023","unstructured":"Patil S, Bhandi S, Bakri MMH, Albar DH, Alzahrani KJ, Al-Ghamdi MS, et al. Evaluation of efficacy of non-resorbable membranes compared to resorbable membranes in patients undergoing guided bone regeneration. Heliyon. 2023;9(3):e13488. https:\/\/doi.org\/10.1016\/j.heliyon.2023.e13488.","journal-title":"Heliyon"},{"issue":"23","key":"1271_CR6","doi-asserted-by":"publisher","first-page":"8284","DOI":"10.3390\/ma15238284","volume":"15","author":"S Bianchi","year":"2022","unstructured":"Bianchi S, Bernardi S, Simeone D, Torge D, Macchiarelli G, Marchetti E. Proliferation and morphological assessment of human periodontal ligament fibroblast towards bovine pericardium membranes: an in vitro study. Materials. 2022;15(23):8284. https:\/\/doi.org\/10.3390\/ma15238284.","journal-title":"Materials"},{"issue":"5","key":"1271_CR7","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1111\/eos.12364","volume":"125","author":"I Elgali","year":"2017","unstructured":"Elgali I, Omar O, Dahlin C, Thomsen P. Guided bone regeneration: materials and biological mechanisms revisited. Eur J Oral Sci. 2017;125(5):315\u201337. https:\/\/doi.org\/10.1111\/eos.12364.","journal-title":"Eur J Oral Sci"},{"key":"1271_CR8","doi-asserted-by":"publisher","first-page":"521547","DOI":"10.1155\/2013\/521547","volume":"2013","author":"G Pellegrini","year":"2013","unstructured":"Pellegrini G, Pagni G, Rasperini G. Surgical approaches based on biological objectives: GTR versus GBR techniques. Int J Dent. 2013;2013:521547. https:\/\/doi.org\/10.1155\/2013\/521547.","journal-title":"Int J Dent"},{"issue":"8","key":"1271_CR9","doi-asserted-by":"publisher","first-page":"1185","DOI":"10.14670\/HH-18-860","volume":"40","author":"S Bernardi","year":"2025","unstructured":"Bernardi S, Marchetti E, Torge D, Simeone D, Macchiarelli G, Bianchi S. Ultrastructural assessment of human periodontal ligament fibroblast interaction with bovine pericardium membranes: an in vitro study. Histol Histopathol. 2025;40(8):1185\u201394. https:\/\/doi.org\/10.14670\/HH-18-860.","journal-title":"Histol Histopathol"},{"issue":"21","key":"1271_CR10","doi-asserted-by":"publisher","first-page":"1806","DOI":"10.3390\/cells13211806","volume":"13","author":"L Sapoznikov","year":"2024","unstructured":"Sapoznikov L, Humphrey M. Progress in dentin-derived bone graft materials: a new xenogeneic dentin-derived material with retained organic component allows for broader and easier application. Cells. 2024;13(21):1806. https:\/\/doi.org\/10.3390\/cells13211806.","journal-title":"Cells"},{"key":"1271_CR11","doi-asserted-by":"publisher","DOI":"10.5772\/intechopen.85452","author":"M Murata","year":"2019","unstructured":"Murata M, Okubo N, Shakya M, Kabir MA, Yokozeki K, Zhu B, et al. Dentin materials as biological scaffolds for tissue engineering. Biomater Tissue Reconstr or Regen. 2019. https:\/\/doi.org\/10.5772\/intechopen.85452.","journal-title":"Biomater Tissue Reconstr or Regen"},{"issue":"3","key":"1271_CR12","doi-asserted-by":"publisher","first-page":"123","DOI":"10.5125\/jkaoms.2019.45.3.123","volume":"45","author":"IW Um","year":"2019","unstructured":"Um IW, Ku JK, Lee BK, Yun PY, Lee JK, Nam JH. Postulated release profile of recombinant human bone morphogenetic protein-2 (rhBMP-2) from demineralized dentin matrix. J Korean Assoc Oral Maxillofac Surg. 2019;45(3):123\u20138. https:\/\/doi.org\/10.5125\/jkaoms.2019.45.3.123.","journal-title":"J Korean Assoc Oral Maxillofac Surg"},{"issue":"9","key":"1271_CR13","doi-asserted-by":"publisher","first-page":"5273","DOI":"10.3390\/ijms23095273","volume":"23","author":"S Bianchi","year":"2022","unstructured":"Bianchi S, Bernardi S, Mattei A, Cristiano L, Mancini L, Torge D, et al. Morphological and biological evaluations of human periodontal ligament fibroblasts in contact with different bovine bone grafts treated with low-temperature deproteinisation protocol. Int J Mol Sci. 2022;23(9):5273. https:\/\/doi.org\/10.3390\/ijms23095273.","journal-title":"Int J Mol Sci"},{"issue":"2","key":"1271_CR14","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1111\/adj.12814","volume":"66","author":"M Korsch","year":"2021","unstructured":"Korsch M. Tooth shell technique: a proof of concept with the use of autogenous dentin block grafts. Aust Dent J. 2021;66(2):159\u201368. https:\/\/doi.org\/10.1111\/adj.12814.","journal-title":"Aust Dent J"},{"issue":"3","key":"1271_CR15","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1089\/ten.teb.2019.0291","volume":"26","author":"IW Um","year":"2020","unstructured":"Um IW, Ku JK, Kim YK, Lee BK, Leem DH. Histological review of demineralized dentin matrix as a carrier of rhBMP-2. Tissue Eng Part B Rev. 2020;26(3):284\u201393. https:\/\/doi.org\/10.1089\/ten.teb.2019.0291.","journal-title":"Tissue Eng Part B Rev"},{"issue":"2","key":"1271_CR16","doi-asserted-by":"publisher","first-page":"189","DOI":"10.21608\/aadj.2021.208221","volume":"4","author":"MA Mizar","year":"2021","unstructured":"Mizar MA, Hassan KS, Mohammed AK, Mwafy IM. Platelet rich fibrin versus collagen membrane combined with beta tri calcium phosphate\/collagen for treatment of dehiscence around immediately placed implants clinical and radiographic comparative study. Al-Azhar Assiut Dental J. 2021;4(2):189\u201396. https:\/\/doi.org\/10.21608\/aadj.2021.208221.","journal-title":"Al-Azhar Assiut Dental J"},{"issue":"9","key":"1271_CR17","doi-asserted-by":"publisher","first-page":"2166","DOI":"10.3390\/ma14092166","volume":"14","author":"JK Ku","year":"2021","unstructured":"Ku JK, Um IW, Jun MK, Kim I. Dentin-derived-barrier membrane in guided bone regeneration: a case report. Materials. 2021;14(9):2166. https:\/\/doi.org\/10.3390\/ma14092166.","journal-title":"Materials"},{"issue":"5","key":"1271_CR18","first-page":"491","volume":"11","author":"N Meredith","year":"1998","unstructured":"Meredith N. Assessment of implant stability as a prognostic determinant. Int J Prosthodont. 1998;11(5):491\u2013501.","journal-title":"Int J Prosthodont"},{"issue":"6","key":"1271_CR19","doi-asserted-by":"publisher","first-page":"1030","DOI":"10.1111\/cid.12680","volume":"20","author":"Y Hamzani","year":"2018","unstructured":"Hamzani Y, Chaushu G. Evaluation of early wound healing scales\/indexes in oral surgery: a literature review. Clin Implant Dent Relat Res. 2018;20(6):1030\u20135. https:\/\/doi.org\/10.1111\/cid.12680.","journal-title":"Clin Implant Dent Relat Res"},{"issue":"4","key":"1271_CR20","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1111\/j.1399-302x.1987.tb00298.x","volume":"2","author":"A Mombelli","year":"1987","unstructured":"Mombelli A, van Oosten MA, Schurch E Jr, Land NP. The microbiota associated with successful or failing osseointegrated titanium implants. Oral Microbiol Immunol. 1987;2(4):145\u201351. https:\/\/doi.org\/10.1111\/j.1399-302x.1987.tb00298.x.","journal-title":"Oral Microbiol Immunol"},{"issue":"1","key":"1271_CR21","first-page":"13","volume":"23","author":"JR Morgulis","year":"1975","unstructured":"Morgulis JR. Indices of periodontal disease. Periodontal Abstr. 1975;23(1):13\u201320.","journal-title":"Periodontal Abstr"},{"issue":"11","key":"1271_CR22","doi-asserted-by":"publisher","first-page":"1373","DOI":"10.1016\/j.ijom.2014.05.021","volume":"43","author":"M Mounir","year":"2014","unstructured":"Mounir M, Beheiri G, El-Beialy W. Assessment of marginal bone loss using full thickness versus partial thickness flaps for alveolar ridge splitting and immediate implant placement in the anterior maxilla. Int J Oral Maxillofac Surg. 2014;43(11):1373\u201380. https:\/\/doi.org\/10.1016\/j.ijom.2014.05.021.","journal-title":"Int J Oral Maxillofac Surg"},{"issue":"7","key":"1271_CR23","doi-asserted-by":"publisher","first-page":"33","DOI":"10.7537\/marsjas160720.06","volume":"16","author":"M Haggag","year":"2020","unstructured":"Haggag M, Said W, Attia A, Tawfik M. Evaluation of bone density after bone condensation around immediate loaded dental implants using different techniques. J Am Sci. 2020;16(7):33\u201342. https:\/\/doi.org\/10.7537\/marsjas160720.06.","journal-title":"J Am Sci"},{"issue":"1","key":"1271_CR24","doi-asserted-by":"publisher","first-page":"46","DOI":"10.4103\/njms.NJMS_59_19","volume":"11","author":"S Kabi","year":"2020","unstructured":"Kabi S, Kar R, Samal D, Deepak KC, Kar IB, Mishra N. Immediate dental implant placement with or without autogenous bone graft: a comparative study. Natl J Maxillofac Surg. 2020;11(1):46\u201352. https:\/\/doi.org\/10.4103\/njms.NJMS_59_19.","journal-title":"Natl J Maxillofac Surg"},{"issue":"3","key":"1271_CR25","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1002\/cap.10202","volume":"13","author":"M Cirmeni","year":"2023","unstructured":"Cirmeni M, Fedele O, Giammarinaro E, Marconcini S, Covani U, Caso G. Immediate implant and socket preservation using sticky bone and leukocyte-platelet-rich fibrin in the anterior maxilla: a 3-year case report. Clin Adv Periodontics. 2023;13(3):144\u20138. https:\/\/doi.org\/10.1002\/cap.10202.","journal-title":"Clin Adv Periodontics"},{"issue":"31","key":"1271_CR26","doi-asserted-by":"publisher","first-page":"8642","DOI":"10.1021\/acs.langmuir.5b02362","volume":"31","author":"W Li","year":"2015","unstructured":"Li W, Ma G, Brazile B, Li N, Dai W, Butler JR, et al. Investigating the potential of amnion-based scaffolds as a barrier membrane for guided bone regeneration. Langmuir. 2015;31(31):8642\u201353. https:\/\/doi.org\/10.1021\/acs.langmuir.5b02362.","journal-title":"Langmuir"},{"issue":"13","key":"1271_CR27","doi-asserted-by":"publisher","first-page":"4661","DOI":"10.3390\/app10134686","volume":"10","author":"IW Um","year":"2020","unstructured":"Um IW, Ku JK, Kim YM, Yun PY, Chang NH, Kim YK, et al. Allogeneic demineralized dentin matrix graft for guided bone regeneration in dental implants. Appl Sci. 2020;10(13):4661\u201374. https:\/\/doi.org\/10.3390\/app10134686.","journal-title":"Appl Sci"},{"issue":"1","key":"1271_CR28","doi-asserted-by":"publisher","first-page":"56","DOI":"10.3390\/medicina58010056","volume":"58","author":"JM Cervera-Maillo","year":"2021","unstructured":"Cervera-Maillo JM, Morales-Schwarz D, Morales-Melendez H, Mahesh L, Calvo-Guirado JL. Autologous tooth dentin graft: a retrospective study in humans. Medicina (B Aires). 2021;58(1):56. https:\/\/doi.org\/10.3390\/medicina58010056.","journal-title":"Medicina (B Aires)"},{"issue":"3","key":"1271_CR29","doi-asserted-by":"publisher","first-page":"211","DOI":"10.21608\/ajdsm.2019.108445","volume":"22","author":"AM Fathy","year":"2019","unstructured":"Fathy AM, Abd-ElAkher MH, Elfeky AA. Effect of using mineralized dentin particulate grafted for socket preservation. Al-Azhar J Dent Sci. 2019;22(3):211\u20135. https:\/\/doi.org\/10.21608\/ajdsm.2019.108445.","journal-title":"Al-Azhar J Dent Sci"},{"issue":"1","key":"1271_CR30","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1186\/s40729-021-00389-w","volume":"7","author":"S Li","year":"2021","unstructured":"Li S, Gao M, Zhou M, Zhu Y. Bone augmentation with autologous tooth shell in the esthetic zone for dental implant restoration: a pilot study. Int J Implant Dent. 2021;7(1):108. https:\/\/doi.org\/10.1186\/s40729-021-00389-w.","journal-title":"Int J Implant Dent"},{"issue":"1","key":"1271_CR31","doi-asserted-by":"publisher","first-page":"642","DOI":"10.1186\/s12903-025-05940-4","volume":"25","author":"KAI Awad","year":"2025","unstructured":"Awad KAI, Tawik MAM, Hussein MM, El-Farag SAA, Sameaa SESA. Tooth shell versus bone shell technique for horizontal maxillary alveolar ridge augmentation. BMC Oral Health. 2025;25(1):642. https:\/\/doi.org\/10.1186\/s12903-025-05940-4.","journal-title":"BMC Oral Health"},{"issue":"6","key":"1271_CR32","doi-asserted-by":"publisher","first-page":"584","DOI":"10.1097\/ID.0000000000000011","volume":"22","author":"YK Kim","year":"2013","unstructured":"Kim YK, Kim SG, Um IW, Kim KW. Bone grafts using autogenous tooth blocks: a case series. Implant Dent. 2013;22(6):584\u201393. https:\/\/doi.org\/10.1097\/ID.0000000000000011.","journal-title":"Implant Dent"},{"issue":"1","key":"1271_CR33","doi-asserted-by":"publisher","first-page":"977","DOI":"10.1186\/s12903-023-03678-5","volume":"23","author":"HAE Elsheikh","year":"2023","unstructured":"Elsheikh HAE, Abdelsameaa SE, Elbahnasi AA, Abdel-Rahman FH. Comparison between platelet rich fibrin as space filling material versus xenograft and alloplastic bone grafting materials in immediate implant placement: a randomized clinical trial. BMC Oral Health. 2023;23(1):977. https:\/\/doi.org\/10.1186\/s12903-023-03678-5.","journal-title":"BMC Oral Health"},{"issue":"1","key":"1271_CR34","doi-asserted-by":"publisher","first-page":"57","DOI":"10.5125\/jkaoms.2021.47.1.57","volume":"47","author":"W Lee","year":"2021","unstructured":"Lee W. Immediate implant placement in fresh extraction sockets. J Korean Assoc Oral Maxillofac Surg. 2021;47(1):57\u201361. https:\/\/doi.org\/10.5125\/jkaoms.2021.47.1.57.","journal-title":"J Korean Assoc Oral Maxillofac Surg"},{"issue":"6","key":"1271_CR35","doi-asserted-by":"publisher","first-page":"3216","DOI":"10.1097\/MS9.0000000000002142","volume":"86","author":"NSH Issa","year":"2024","unstructured":"Issa NSH, Othman TA, Sleman BM. A comparative radiographic study of bone density changes around titanium implants in the posterior mandible, preoperative, and postoperative. Ann Med Surg (Lond). 2024;86(6):3216\u201321. https:\/\/doi.org\/10.1097\/MS9.0000000000002142.","journal-title":"Ann Med Surg (Lond)"},{"issue":"1","key":"1271_CR36","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1111\/cid.12702","volume":"21","author":"A Brizuela-Velasco","year":"2019","unstructured":"Brizuela-Velasco A, Ch\u00e1varri-Prado D. The functional loading of implants increases their stability: a retrospective clinical study. Clin Implant Dent Relat Res. 2019;21(1):122\u20139. https:\/\/doi.org\/10.1111\/cid.12702.","journal-title":"Clin Implant Dent Relat Res"},{"issue":"4","key":"1271_CR37","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1016\/j.ijom.2024.12.011","volume":"54","author":"P Witoonkitvanich","year":"2025","unstructured":"Witoonkitvanich P, Amornsettachai P, Panyayong W, Rokaya D, Vongsirichat N, Suphangul S. Comparison of the stability of immediate dental implant placement in fresh molar extraction sockets in the maxilla and mandible: a controlled, prospective, non-randomized clinical trial. Int J Oral Maxillofac Surg. 2025;54(4):365\u201373. https:\/\/doi.org\/10.1016\/j.ijom.2024.12.011.","journal-title":"Int J Oral Maxillofac Surg"},{"issue":"3","key":"1271_CR38","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1034\/j.1600-0501.2003.00972.x","volume":"14","author":"T Berglundh","year":"2003","unstructured":"Berglundh T, Abrahamsson I, Lang NP, Lindhe J. De novo alveolar bone formation adjacent to endosseous implants: a model study in the dog. Clin Oral Implants Res. 2003;14(3):251\u201362. https:\/\/doi.org\/10.1034\/j.1600-0501.2003.00972.x.","journal-title":"Clin Oral Implants Res"},{"issue":"10","key":"1271_CR39","doi-asserted-by":"publisher","first-page":"1725","DOI":"10.3390\/jpm12101725","volume":"12","author":"E Ferr\u00e9s-Amat","year":"2022","unstructured":"Ferr\u00e9s-Amat E, Al Madhoun A, Ferr\u00e9s-Amat E, Carri\u00f3 N, Barajas M, Al-Madhoun AS, et al. Comparison of 0.12% chlorhexidine and a new bone bioactive liquid, BBL, in mouthwash for oral wound healing: a randomized, double blind clinical human trial. J Pers Med. 2022;12(10):1725. https:\/\/doi.org\/10.3390\/jpm12101725.","journal-title":"J Pers Med"},{"issue":"1","key":"1271_CR40","doi-asserted-by":"publisher","first-page":"110","DOI":"10.21608\/adjalexu.2024.240808.1424","volume":"50","author":"S Elsheikh","year":"2025","unstructured":"Elsheikh S, Noureldin M. Evaluation of bone augmentation using autologous tooth shell in the esthetic zone of narrow maxilla (a clinical study). Alexandria Dent J. 2025;50(1):110\u20136. https:\/\/doi.org\/10.21608\/adjalexu.2024.240808.1424.","journal-title":"Alexandria Dent J"},{"issue":"1","key":"1271_CR41","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1186\/s40729-019-0201-7","volume":"6","author":"HJA Meijer","year":"2020","unstructured":"Meijer HJA, Raghoebar GM. Immediate implant placement in molar extraction sites: a 1-year prospective case series pilot study. Int J Implant Dent. 2020;6(1):3. https:\/\/doi.org\/10.1186\/s40729-019-0201-7.","journal-title":"Int J Implant Dent"},{"issue":"1","key":"1271_CR42","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1111\/prd.12584","volume":"95","author":"A Monje","year":"2024","unstructured":"Monje A, Salvi GE. Diagnostic methods\/parameters to monitor peri\u2010implant conditions. Periodontol 2000. 2024;95(1):20\u201339. https:\/\/doi.org\/10.1111\/prd.12584.","journal-title":"Periodontol 2000"},{"issue":"6","key":"1271_CR43","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1016\/S0300-9785(81)80077-4","volume":"10","author":"R Adell","year":"1981","unstructured":"Adell R, Lekholm U, Rockler B, Br\u00e5nemark PI. A 15-year study of osseointegrated implants in the treatment of the edentulous jaw. Int J Oral Surg. 1981;10(6):387\u2013416. https:\/\/doi.org\/10.1016\/S0300-9785(81)80077-4.","journal-title":"Int J Oral Surg"},{"issue":"3","key":"1271_CR44","doi-asserted-by":"publisher","first-page":"608","DOI":"10.3390\/molecules27030608","volume":"27","author":"W Bungthong","year":"2022","unstructured":"Bungthong W, Amornsettachai P, Luangchana P, Chuenjitkuntaworn B, Suphangul S. Bone dimensional change following immediate implant placement in posterior teeth with CBCT: a 6-month prospective clinical study. Molecules. 2022;27(3):608. https:\/\/doi.org\/10.3390\/molecules27030608.","journal-title":"Molecules"},{"issue":"2","key":"1271_CR45","first-page":"169","volume":"10","author":"M Tallarico","year":"2017","unstructured":"Tallarico M, Xhanari E, Pisano M, Gatti F, Meloni SM. Molar replacement with 7 mm-wide diameter implants: to place the implant immediately or to wait 4 months after socket preservation? 1 year after loading results from a randomised controlled trial. Eur J Oral Implant. 2017;10(2):169\u201378.","journal-title":"Eur J Oral Implant"},{"issue":"3","key":"1271_CR46","first-page":"263","volume":"10","author":"V Checchi","year":"2017","unstructured":"Checchi V, Felice P, Zucchelli G, Barausse C, Piattelli M, Pistilli R, et al. Wide diameter immediate post-extractive implants vs delayed placement of normal-diameter implants in preserved sockets in the molar region: 1-year post-loading outcome of a randomised controlled trial. Eur J Oral Implantol. 2017;10(3):263\u201378.","journal-title":"Eur J Oral Implantol"}],"container-title":["Odontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10266-025-01271-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10266-025-01271-6","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10266-025-01271-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T21:15:55Z","timestamp":1790889355000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10266-025-01271-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,10]]},"references-count":46,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["1271"],"URL":"https:\/\/doi.org\/10.1007\/s10266-025-01271-6","relation":{},"ISSN":["1618-1247","1618-1255"],"issn-type":[{"value":"1618-1247","type":"print"},{"value":"1618-1255","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,10]]},"assertion":[{"value":"16 October 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 November 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 December 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no conflict of interests.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Under protocol number A04010222, the current study was authorized by the Ethical Committee of the Faculty of Dentistry, Mansoura University, Mansoura, Egypt, in accordance with the seventh revision of the Helsinki Declaration in 2013. On 26\/9\/2024, Clinical-Trials.gov PRS (\n                      \n                      ) has this study registered under the identifier number. NCT06615362.","order":2,"name":"Ethics","label":"Ethical approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Each participant signed a written informed consent form for participation in this study.","order":3,"name":"Ethics","label":"Informed consent","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":4,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}}]}}