{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T02:47:02Z","timestamp":1782096422600,"version":"3.54.5"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T00:00:00Z","timestamp":1782086400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T00:00:00Z","timestamp":1782086400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"The project of the scientific research team of Kunming Medical University Haiyuan College","award":["2024TD003"],"award-info":[{"award-number":["2024TD003"]}]},{"name":"Research Fund Project of the Education Department of Yunnan Province","award":["2026J1374"],"award-info":[{"award-number":["2026J1374"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Odontology"],"DOI":"10.1007\/s10266-026-01468-3","type":"journal-article","created":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T01:48:04Z","timestamp":1782092884000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Long non-coding RNA FOXD2-AS1 promotes inflammation but suppresses osteogenesis in pulpitis via miR-338-3p\/THBS1 axis"],"prefix":"10.1007","author":[{"given":"Huawen","family":"Cui","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanmei","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yajun","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengyi","family":"Chu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,6,22]]},"reference":[{"issue":"1","key":"1468_CR1","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1186\/s40814-022-01029-9","volume":"8","author":"JE Clarkson","year":"2022","unstructured":"Clarkson JE, Ramsay CR, Mannocci F, Jarad F, Albadri S, Ricketts D, et al. Pulpotomy for the management of irreversible pulpitis in mature teeth (PIP): a feasibility study. Pilot feasibility Stud. 2022;8(1):77. https:\/\/doi.org\/10.1186\/s40814-022-01029-9.","journal-title":"Pilot feasibility Stud"},{"key":"1468_CR2","doi-asserted-by":"publisher","DOI":"10.3390\/dj8040131","author":"S Hirata-Tsuchiya","year":"2020","unstructured":"Hirata-Tsuchiya S, Suzuki S, Nakamoto T, Kakimoto N, Yamada S, Shiba H. Surgical sealing of laterally localized accessory root canal with resin containing S-PRG filler in combination with non-surgical endodontic treatment: a case report. Dentistry J. 2020 https:\/\/doi.org\/10.3390\/dj8040131.","journal-title":"Dentistry"},{"issue":"1","key":"1468_CR3","doi-asserted-by":"publisher","first-page":"7552","DOI":"10.1080\/21655979.2021.1979914","volume":"12","author":"P Zhang","year":"2021","unstructured":"Zhang P, Cui Z, Li S. The protective effects of S14G-humanin (HNG) against lipopolysaccharide (LPS)- induced inflammatory response in human dental pulp cells (hDPCs) mediated by the TLR4\/MyD88\/NF-\u03baB pathway. Bioengineered. 2021;12(1):7552\u201362. https:\/\/doi.org\/10.1080\/21655979.2021.1979914.","journal-title":"Bioengineered"},{"key":"1468_CR4","doi-asserted-by":"publisher","first-page":"3892685","DOI":"10.1155\/2016\/3892685","volume":"2016","author":"L Liu","year":"2016","unstructured":"Liu L, Shu S, Cheung GS, Wei X. Effect of miR-146a\/bFGF\/PEG-PEI Nanoparticles on inflammation response and tissue regeneration of human dental pulp cells. Biomed Res Int. 2016;2016:3892685. https:\/\/doi.org\/10.1155\/2016\/3892685.","journal-title":"Biomed Res Int"},{"issue":"3","key":"1468_CR5","first-page":"201","volume":"2","author":"F Fonzar","year":"2009","unstructured":"Fonzar F, Fonzar A, Buttolo P, Worthington HV, Esposito M. The prognosis of root canal therapy: a 10-year retrospective cohort study on 411 patients with 1175 endodontically treated teeth. Eur J Oral Implantol. 2009;2(3):201\u20138.","journal-title":"Eur J Oral Implantol"},{"issue":"1","key":"1468_CR6","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1007\/s11033-025-10281-0","volume":"52","author":"F Kavakebian","year":"2025","unstructured":"Kavakebian F, Rezapour A, Seyedebrahimi R, Eslami Farsani M, Jabbari Fakhr M, Zare Jalise S, et al. Intrinsic and extrinsic modulators of human dental pulp stem cells: advancing strategies for tissue engineering applications. Mol Biol Rep. 2025;52(1):190. https:\/\/doi.org\/10.1007\/s11033-025-10281-0.","journal-title":"Mol Biol Rep"},{"issue":"2","key":"1468_CR7","doi-asserted-by":"publisher","first-page":"884","DOI":"10.3892\/etm.2021.10316","volume":"22","author":"L Qiao","year":"2021","unstructured":"Qiao L, Peng SY, Zhou YP, Yin J, Xu JP, Chen B, et al. Long non-coding RNA RP11-81H3.2 suppresses apoptosis by targeting microRNA-1539\/COL2A1 in human nucleus pulposus cells. Experimental therapeutic Med. 2021;22(2):884. https:\/\/doi.org\/10.3892\/etm.2021.10316.","journal-title":"Experimental therapeutic Med"},{"issue":"16","key":"1468_CR8","doi-asserted-by":"publisher","first-page":"e25244","DOI":"10.1097\/md.0000000000025244","volume":"100","author":"H Hua","year":"2021","unstructured":"Hua H, Wang J, Zhong P, Mou T, Liu P, Xie F. The clinical prognostic value of lncRNA LINC00675 in cancer patients: a meta-analysis. Medicine. 2021;100(16):e25244. https:\/\/doi.org\/10.1097\/md.0000000000025244.","journal-title":"Medicine"},{"key":"1468_CR9","doi-asserted-by":"publisher","first-page":"7222092","DOI":"10.1155\/2022\/7222092","volume":"2022","author":"J Du","year":"2022","unstructured":"Du J, Liu L, Yang F, Leng S, Zhang L, Huang D. Identification of immune-related lncRNA regulatory network in pulpitis. Dis Markers. 2022;2022:7222092. https:\/\/doi.org\/10.1155\/2022\/7222092.","journal-title":"Dis Markers"},{"issue":"1","key":"1468_CR10","doi-asserted-by":"publisher","first-page":"104027","DOI":"10.1016\/j.identj.2025.104027","volume":"76","author":"J Xu","year":"2026","unstructured":"Xu J, Lv D, Yuan C, Huang L. Dysregulation of pulpitis progression through modulation of the lncRNA ITGB2-AS1 \/miR-1224-5p axis. Int Dent J. 2026;76(1):104027. https:\/\/doi.org\/10.1016\/j.identj.2025.104027.","journal-title":"Int Dent J"},{"key":"1468_CR11","doi-asserted-by":"publisher","first-page":"263","DOI":"10.3290\/j.ohpd.b3147193","volume":"20","author":"L Xia","year":"2022","unstructured":"Xia L, Wang J, Qi Y, Fei Y, Wang D. Long non-coding RNA PVT1 is involved in the pathological mechanism of pulpitis by regulating miR-128-3p. Oral Health Prev Dent. 2022;20:263\u201370. https:\/\/doi.org\/10.3290\/j.ohpd.b3147193.","journal-title":"Oral Health Prev Dent"},{"issue":"36","key":"1468_CR12","doi-asserted-by":"publisher","first-page":"5020","DOI":"10.1038\/s41388-018-0308-y","volume":"37","author":"TP Xu","year":"2018","unstructured":"Xu TP, Wang WY, Ma P, Shuai Y, Zhao K, Wang YF, et al. Upregulation of the long noncoding RNA FOXD2-AS1 promotes carcinogenesis by epigenetically silencing EphB3 through EZH2 and LSD1, and predicts poor prognosis in gastric cancer. Oncogene. 2018;37(36):5020\u201336. https:\/\/doi.org\/10.1038\/s41388-018-0308-y.","journal-title":"Oncogene"},{"issue":"1","key":"1468_CR13","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1186\/s12903-024-04388-2","volume":"24","author":"S Guo","year":"2024","unstructured":"Guo S, Huang B, You Z, Luo Z, Xu D, Zhang J, et al. FOXD2-AS1 promotes malignant cell behavior in oral squamous cell carcinoma via the miR-378\u00a0g\/CRABP2 axis. BMC Oral Health. 2024;24(1):625. https:\/\/doi.org\/10.1186\/s12903-024-04388-2.","journal-title":"BMC Oral Health"},{"issue":"1","key":"1468_CR14","doi-asserted-by":"publisher","first-page":"1241","DOI":"10.1080\/21691401.2019.1596940","volume":"47","author":"Y Wang","year":"2019","unstructured":"Wang Y, Cao L, Wang Q, Huang J, Xu S. LncRNA FOXD2-AS1 induces chondrocyte proliferation through sponging miR-27a-3p in osteoarthritis. Artif cells Nanomed Biotechnol. 2019;47(1):1241\u20137. https:\/\/doi.org\/10.1080\/21691401.2019.1596940.","journal-title":"Artif cells Nanomed Biotechnol"},{"issue":"1","key":"1468_CR15","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1186\/s13018-023-03681-0","volume":"18","author":"X Ke","year":"2023","unstructured":"Ke X, Zhang W. Pro-inflammatory activity of long noncoding RNA FOXD2-AS1 in Achilles tendinopathy. J Orthop Surg Res. 2023;18(1):361. https:\/\/doi.org\/10.1186\/s13018-023-03681-0.","journal-title":"J Orthop Surg Res"},{"issue":"5","key":"1468_CR16","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1016\/j.prp.2019.01.033","volume":"215","author":"Q Hu","year":"2019","unstructured":"Hu Q, Tai S, Wang J. Oncogenicity of lncRNA FOXD2-AS1 and its molecular mechanisms in human cancers. Pathol Res Pract. 2019;215(5):843\u20138. https:\/\/doi.org\/10.1016\/j.prp.2019.01.033.","journal-title":"Pathol Res Pract"},{"issue":"10","key":"1468_CR17","doi-asserted-by":"publisher","first-page":"1954","DOI":"10.1007\/s12094-022-02850-7","volume":"24","author":"D Luo","year":"2022","unstructured":"Luo D, Salai A, Lv H, Wang Y, Gao Y. FOXD2-AS1 acts an oncogene in esophageal squamous cell carcinoma through sponging miR-204-3p. Clin Trans Oncol. 2022;24(10):1954\u201363. https:\/\/doi.org\/10.1007\/s12094-022-02850-7.","journal-title":"Clin Trans Oncol"},{"key":"1468_CR18","doi-asserted-by":"publisher","first-page":"1220","DOI":"10.1016\/j.biopha.2018.07.048","volume":"106","author":"L Cao","year":"2018","unstructured":"Cao L, Wang Y, Wang Q, Huang J. LncRNA FOXD2-AS1 regulates chondrocyte proliferation in osteoarthritis by acting as a sponge of miR-206 to modulate CCND1 expression. Biomed Pharmacother. 2018;106:1220\u20136. https:\/\/doi.org\/10.1016\/j.biopha.2018.07.048.","journal-title":"Biomed Pharmacother"},{"issue":"3","key":"1468_CR19","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1007\/s10735-022-10070-0","volume":"53","author":"J Zhou","year":"2022","unstructured":"Zhou J, Sun C, Dong X, Wang H. A novel miR-338-3p\/SLC1A5 axis reprograms retinal pigment epithelium to increases its resistance to high glucose-induced cell ferroptosis. J Mol Histol. 2022;53(3):561\u201371. https:\/\/doi.org\/10.1007\/s10735-022-10070-0.","journal-title":"J Mol Histol"},{"issue":"7","key":"1468_CR20","doi-asserted-by":"publisher","first-page":"8514","DOI":"10.3390\/ijms13078514","volume":"13","author":"X Fu","year":"2012","unstructured":"Fu X, Tan D, Hou Z, Hu Z, Liu G. miR-338-3p is down-regulated by hepatitis B virus X and inhibits cell proliferation by targeting the 3\u2019-UTR region of CyclinD1. Int J Mol Sci. 2012;13(7):8514\u201339. https:\/\/doi.org\/10.3390\/ijms13078514.","journal-title":"Int J Mol Sci"},{"key":"1468_CR21","doi-asserted-by":"publisher","DOI":"10.1016\/j.trim.2022.101681","author":"J Yang","year":"2023","unstructured":"Yang J, Huang Q, Liao P, Zhang P, Sun S, Xu Q. Mechanism of miR-338-3p in sepsis-induced acute lung injury via indirectly modulating ATF4. Transpl Immunol. 2023 https:\/\/doi.org\/10.1016\/j.trim.2022.101681.","journal-title":"Transpl Immunol"},{"issue":"3","key":"1468_CR22","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1007\/s10863-023-09992-5","volume":"56","author":"L Lin","year":"2024","unstructured":"Lin L, Wang L, Li A, Li Y, Gu X. CircDiaph3 aggravates H\/R-induced cardiomyocyte apoptosis and inflammation through miR-338-3p\/SRSF1 axis. J Bioenerg Biomembr. 2024;56(3):235\u201345. https:\/\/doi.org\/10.1007\/s10863-023-09992-5.","journal-title":"J Bioenerg Biomembr"},{"issue":"1","key":"1468_CR23","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1186\/s13018-022-03437-2","volume":"17","author":"C Li","year":"2022","unstructured":"Li C, Li W, Pu G, Wu J, Qin F. Exosomes derived from miR-338-3p-modified adipose stem cells inhibited inflammation injury of chondrocytes via targeting RUNX2 in osteoarthritis. J Orthop Surg Res. 2022;17(1):567. https:\/\/doi.org\/10.1186\/s13018-022-03437-2.","journal-title":"J Orthop Surg Res"},{"issue":"1","key":"1468_CR24","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1186\/s12916-024-03318-x","volume":"22","author":"HM Hassan","year":"2024","unstructured":"Hassan HM, Liang X, Xin J, Lu Y, Cai Q, Shi D, et al. Thrombospondin 1 enhances systemic inflammation and disease severity in acute-on-chronic liver failure. BMC Med. 2024;22(1):95. https:\/\/doi.org\/10.1186\/s12916-024-03318-x.","journal-title":"BMC Med"},{"issue":"1","key":"1468_CR25","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1186\/s12974-025-03382-x","volume":"22","author":"C Liu","year":"2025","unstructured":"Liu C, Sui H, Li Z, Sun Z, Li C, Chen G, et al. THBS1 in macrophage-derived exosomes exacerbates cerebral ischemia-reperfusion injury by inducing ferroptosis in endothelial cells. J Neuroinflamm. 2025;22(1):48. https:\/\/doi.org\/10.1186\/s12974-025-03382-x.","journal-title":"J Neuroinflamm"},{"issue":"3","key":"1468_CR26","doi-asserted-by":"publisher","first-page":"168139","DOI":"10.1016\/j.bbadis.2025.168139","volume":"1872","author":"W Huang","year":"2026","unstructured":"Huang W, Zhou C, Wu R, Zhao K, Wu J, Song D. Neutrophil-derived thrombospondin-1 (THBS1) drives type 2 diabetes-induced osteoporosis via CD36-PPAR\u03b3-POU2F2 signaling. Biochim et Biophys Acta Mol Basis Dis. 2026;1872(3):168139. https:\/\/doi.org\/10.1016\/j.bbadis.2025.168139.","journal-title":"Biochim et Biophys Acta Mol Basis Dis"},{"key":"1468_CR27","doi-asserted-by":"publisher","first-page":"1166934","DOI":"10.3389\/fcell.2023.1166934","volume":"11","author":"W Zhang","year":"2023","unstructured":"Zhang W, Xu T, Li X, Zhang Y, Zou X, Chen F, et al. Single-cell atlas of dental pulp stem cells exposed to the oral bacteria Porphyromonas gingivalis and Enterococcus faecalis. Front Cell Dev Biol. 2023;11:1166934. https:\/\/doi.org\/10.3389\/fcell.2023.1166934.","journal-title":"Front Cell Dev Biol"},{"issue":"Suppl 3","key":"1468_CR28","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1111\/iej.13974","volume":"56","author":"HF Duncan","year":"2023","unstructured":"Duncan HF, Kirkevang LL, Peters OA, El-Karim I, Krastl G, Del Fabbro M, et al. Treatment of pulpal and apical disease: The European Society of Endodontology (ESE) S3-level clinical practice guideline. Int Endod J. 2023;56(Suppl 3):238\u201395. https:\/\/doi.org\/10.1111\/iej.13974.","journal-title":"Int Endod J"},{"key":"1468_CR29","doi-asserted-by":"publisher","first-page":"4459","DOI":"10.2147\/jir.S504048","volume":"18","author":"L Li","year":"2025","unstructured":"Li L, Wang Y, Hu M. Dysregulation of lncRNA GATA3-AS1 is Involved in the pathogenesis of pulpitis by the regulation of miR-17-3p. J Inflamm Res. 2025;18:4459\u201369. https:\/\/doi.org\/10.2147\/jir.S504048.","journal-title":"J Inflamm Res"},{"issue":"4","key":"1468_CR30","doi-asserted-by":"publisher","first-page":"100866","DOI":"10.1016\/j.identj.2025.100866","volume":"75","author":"F Wu","year":"2025","unstructured":"Wu F, Jiang Z, Long Noncoding. RNA MIR4435-2HG is involved in osteogenic differentiation and inflammation in human dental pulp stem cells. Int Dent J. 2025;75(4):100866. https:\/\/doi.org\/10.1016\/j.identj.2025.100866.","journal-title":"Int Dent J"},{"issue":"11","key":"1468_CR31","doi-asserted-by":"publisher","first-page":"e70083","DOI":"10.1111\/1440-1681.70083","volume":"52","author":"T Yi","year":"2025","unstructured":"Yi T, Gu F, Liu S, Li Q, Wang L, Yin W. The health education during root canal therapy reduces the use of antibiotics. Clin Exp Pharmacol Physiol. 2025;52(11):e70083. https:\/\/doi.org\/10.1111\/1440-1681.70083.","journal-title":"Clin Exp Pharmacol Physiol"},{"issue":"9","key":"1468_CR32","doi-asserted-by":"publisher","first-page":"e0185512","DOI":"10.1371\/journal.pone.0185512","volume":"12","author":"D Su","year":"2017","unstructured":"Su D, Hu X, Wang D, Cui T, Yao R, Sun H. Semiconductor laser irradiation improves root canal sealing during routine root canal therapy. PLoS ONE. 2017;12(9):e0185512. https:\/\/doi.org\/10.1371\/journal.pone.0185512","journal-title":"PLoS ONE"},{"issue":"5","key":"1468_CR33","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1080\/08916934.2021.1919879","volume":"54","author":"Q Zhao","year":"2021","unstructured":"Zhao Q, Zhao F, Liu C, Xu T, Song K. LncRNA FOXD2-AS1 promotes cell proliferation and invasion of fibroblast-like synoviocytes by regulation of miR-331-3p\/PIAS3 pathway in rheumatoid arthritis. Autoimmunity. 2021;54(5):254\u201363. https:\/\/doi.org\/10.1080\/08916934.2021.1919879.","journal-title":"Autoimmunity"},{"key":"1468_CR34","doi-asserted-by":"publisher","DOI":"10.1042\/bsr20190372","author":"Y Zhang","year":"2020","unstructured":"Zhang Y, Liang C, Zhang Y, Wang Z, Li R, Wei Z, et al. The role of FOXD2-AS1 in cancer: a comprehensive study based on data mining and published articles. Biosci Rep. 2020 https:\/\/doi.org\/10.1042\/bsr20190372.","journal-title":"Biosci Rep"},{"issue":"2","key":"1468_CR35","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1016\/j.amjms.2021.01.020","volume":"362","author":"F Duan","year":"2021","unstructured":"Duan F, Li H, Liu W, Zhao J, Yang Z, Zhang J, Long Non-Coding RNA. FOXD2-AS1 serves as a potential prognostic biomarker for patients with cancer: a meta-analysis and database testing. Am J Med Sci. 2021;362(2):173\u201381. https:\/\/doi.org\/10.1016\/j.amjms.2021.01.020.","journal-title":"Am J Med Sci"},{"issue":"16","key":"1468_CR36","doi-asserted-by":"publisher","first-page":"e35442","DOI":"10.1016\/j.heliyon.2024.e35442","volume":"10","author":"C Zhou","year":"2024","unstructured":"Zhou C, Wu Y, Teng Y, Zhang J, Liu J. BRF1 promotes the odontogenic differentiation of dental pulp stem cells in pulpitis by inducing autophagy. Heliyon. 2024;10(16):e35442. https:\/\/doi.org\/10.1016\/j.heliyon.2024.e35442.","journal-title":"Heliyon"},{"key":"1468_CR37","doi-asserted-by":"publisher","DOI":"10.3390\/biom14030368","author":"Y Wang","year":"2024","unstructured":"Wang Y, Xie Y, Xue N, Xu H, Zhang D, Ji N, et al. TSG-6 Inhibits the NF-\u03baB signaling pathway and promotes the odontogenic differentiation of dental pulp stem cells via CD44 in an inflammatory environment. Biomolecules. 2024 https:\/\/doi.org\/10.3390\/biom14030368.","journal-title":"Biomolecules"},{"key":"1468_CR38","doi-asserted-by":"publisher","first-page":"e7135","DOI":"10.7717\/peerj.7135","volume":"7","author":"F Lei","year":"2019","unstructured":"Lei F, Zhang H, Xie X. Comprehensive analysis of an lncRNA-miRNA-mRNA competing endogenous RNA network in pulpitis. PeerJ. 2019;7:e7135. https:\/\/doi.org\/10.7717\/peerj.7135.","journal-title":"PeerJ"},{"issue":"3","key":"1468_CR39","doi-asserted-by":"publisher","first-page":"1579","DOI":"10.1016\/j.jds.2022.05.010","volume":"20","author":"J Li","year":"2025","unstructured":"Li J, Wang Z. A novel NUTM2A-AS1\/miR-769-5p axis regulates LPS-evoked damage in human dental pulp cells via the TLR4\/MYD88\/NF-\u03baB signaling. J Dent Sci. 2025;20(3):1579\u201389. https:\/\/doi.org\/10.1016\/j.jds.2022.05.010.","journal-title":"J Dent Sci"},{"key":"1468_CR40","doi-asserted-by":"publisher","DOI":"10.12307\/2025.281","author":"ZY Lang Mecuo","year":"2025","unstructured":"Lang Mecuo ZY, Wang Li. MiR-338-3p affects proliferation and apoptosis of alveolar bone osteoblasts by targeting receptor activator of nuclear factor-kappaB ligand. Chin J Tissue Eng Res. 2025. https:\/\/doi.org\/10.12307\/2025.281.","journal-title":"Chin J Tissue Eng Res"},{"key":"1468_CR41","doi-asserted-by":"publisher","DOI":"10.3390\/proteomes13020025","author":"D Perico","year":"2025","unstructured":"Perico D, Mauri P. Deciphering radiotherapy resistance: a proteomic perspective. Proteomes. 2025 https:\/\/doi.org\/10.3390\/proteomes13020025","journal-title":"Proteomes"},{"key":"1468_CR42","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinsp.2025.100631","author":"X Xie","year":"2025","unstructured":"Xie X, Li R, Mi F. hsa_circ_0095812 accelerates periodontitis progression by adsorbing miR-485-3p-mediated THBS1 expression. Clinics (Sao Paulo Brazil). 2025 https:\/\/doi.org\/10.1016\/j.clinsp.2025.100631.","journal-title":"Clinics (Sao Paulo Brazil)"},{"key":"1468_CR43","doi-asserted-by":"publisher","DOI":"10.1007\/s00795-025-00451-1","author":"Y Tu","year":"2025","unstructured":"Tu Y, Gu X. THBS1 inhibition alleviates inflammatory response by inhibiting TGF-\u03b2 and NLRP3 inflammasome in experimental murine dry eye. Med Mol Morphol. 2025. https:\/\/doi.org\/10.1007\/s00795-025-00451-1.","journal-title":"Med Mol Morphol"},{"issue":"3","key":"1468_CR44","doi-asserted-by":"publisher","first-page":"17","DOI":"10.15586\/aei.v53i3.1225","volume":"53","author":"F Wang","year":"2025","unstructured":"Wang F, Xie R. Knockdown of THBS1 inhibits inflammatory damage and oxidative stress in in vitro pneumonia model by regulating NF-\u03baB signaling pathway. Allergol Immunopathol. 2025;53(3):17\u201322. https:\/\/doi.org\/10.15586\/aei.v53i3.1225.","journal-title":"Allergol Immunopathol"}],"container-title":["Odontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10266-026-01468-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10266-026-01468-3","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10266-026-01468-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T01:48:06Z","timestamp":1782092886000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10266-026-01468-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,22]]},"references-count":44,"alternative-id":["1468"],"URL":"https:\/\/doi.org\/10.1007\/s10266-026-01468-3","relation":{},"ISSN":["1618-1247","1618-1255"],"issn-type":[{"value":"1618-1247","type":"print"},{"value":"1618-1255","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,22]]},"assertion":[{"value":"23 March 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 June 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 June 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The Ethics Committee of Harbin Stomatological Hospital approved this study (Approval Number: No. 2022-015). All methods were performed in accordance with relevant guidelines, regulations and the Declaration of Helsinki. Written informed consent was collected from all participants.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical considerations and patient consent statement"}},{"value":"The authors declare that they did not use artificial intelligence (AI) or any AI-assisted technologies in the elaboration of the article.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Artificial intelligence"}}]}}