{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T14:16:56Z","timestamp":1788013016790,"version":"build-2784847793"},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2018,1,24]],"date-time":"2018-01-24T00:00:00Z","timestamp":1516752000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Auton Res"],"published-print":{"date-parts":[[2018,12]]},"DOI":"10.1007\/s10286-018-0502-6","type":"journal-article","created":{"date-parts":[[2018,1,24]],"date-time":"2018-01-24T06:12:02Z","timestamp":1516774322000},"page":"569-576","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Lateral medullary infarction with cardiovascular autonomic dysfunction: an unusual presentation with review of the literature"],"prefix":"10.1007","volume":"28","author":[{"given":"Tridu R.","family":"Huynh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Decker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy J.","family":"Fries","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajay","family":"Tunguturi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,1,24]]},"reference":[{"key":"502_CR1","doi-asserted-by":"publisher","first-page":"6301430","DOI":"10.1155\/2017\/6301430","volume":"2017","author":"AA Alsaad","year":"2017","unstructured":"Alsaad AA, Austin CO, Robinson MT, Phillips MB (2017) Pacemaker placement in patients with stroke-mediated autonomic dysregulation. Case Rep Med 2017:6301430","journal-title":"Case Rep Med"},{"key":"502_CR2","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1007\/s10194-012-0427-8","volume":"13","author":"R Altavilla","year":"2012","unstructured":"Altavilla R, Landi D, Altamura C, Bussone G, Maggio P, Corbetto M, Scrascia F, Vernieri F (2012) Dorsolateral medullary ischemic infarction causing autonomic dysfunction and headache: a case report. J Headache Pain 13:327\u2013330","journal-title":"J Headache Pain"},{"key":"502_CR3","doi-asserted-by":"publisher","first-page":"R1269","DOI":"10.1152\/ajpregu.00422.2010","volume":"299","author":"SM Barman","year":"2010","unstructured":"Barman SM, Orer HS (2010) Rostral ventrolateral medullary but not medullary lateral tegmental field neurons mediate sympatho-sympathetic reflexes in cats. Am J Physiol Regul Integr Comp Physiol 299:R1269\u2013R1278","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"502_CR4","doi-asserted-by":"publisher","first-page":"882","DOI":"10.1212\/WNL.48.4.882","volume":"48","author":"C Bassetti","year":"1997","unstructured":"Bassetti C, Bogousslavsky J, Mattle H, Bernasconi A (1997) Medial medullary stroke: report of seven patients and review of the literature. Neurology 48:882\u2013890","journal-title":"Neurology"},{"key":"502_CR5","doi-asserted-by":"publisher","first-page":"1733","DOI":"10.1212\/01.wnl.0000335246.93495.92","volume":"71","author":"EE Benarroch","year":"2008","unstructured":"Benarroch EE (2008) The arterial baroreflex: functional organization and involvement in neurologic disease. Neurology 71:1733\u20131738","journal-title":"Neurology"},{"key":"502_CR6","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1161\/01.HYP.23.4.491","volume":"23","author":"I Biaggioni","year":"1994","unstructured":"Biaggioni I, Whetsell WO, Jobe J, Nadeau JH (1994) Baroreflex failure in a patient with central nervous system lesions involving the nucleus tractus solitarii. Hypertension 23:491\u2013495","journal-title":"Hypertension"},{"key":"502_CR7","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1111\/j.1468-1331.2008.02381.x","volume":"16","author":"C Eggers","year":"2009","unstructured":"Eggers C, Fink GR, Moller-Hartmann W, Nowak DA (2009) Correlation of anatomy and function in medulla oblongata infarction. Eur J Neurol 16:201\u2013204","journal-title":"Eur J Neurol"},{"key":"502_CR8","doi-asserted-by":"publisher","first-page":"594","DOI":"10.1016\/j.jstrokecerebrovasdis.2011.01.008","volume":"21","author":"T Fukuoka","year":"2012","unstructured":"Fukuoka T, Takeda H, Dembo T, Nagoya H, Kato Y, Deguchi I, Maruyama H, Horiuchi Y, Uchino A, Yamazaki S, Tanahashi N (2012) Clinical review of 37 patients with medullary infarction. J Stroke Cerebrovasc Dis 21:594\u2013599","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"502_CR9","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1111\/j.1526-4610.2004.04012.x","volume":"44","author":"AV Galende","year":"2004","unstructured":"Galende AV, Camacho A, Gomez-Escalonilla C, Penas M, Juntas R, Ramos A, Esteban J (2004) Lateral medullary infarction secondary to vertebral artery dissection presenting as a trigeminal autonomic cephalalgia. Headache 44:70\u201374","journal-title":"Headache"},{"key":"502_CR10","first-page":"130","volume":"69","author":"B Gandhavadi","year":"1988","unstructured":"Gandhavadi B (1988) Hypertension after brainstem stroke. Arch Phys Med Rehabil 69:130\u2013131","journal-title":"Arch Phys Med Rehabil"},{"key":"502_CR11","doi-asserted-by":"publisher","first-page":"1460","DOI":"10.1002\/cne.22283","volume":"518","author":"JC Geerling","year":"2010","unstructured":"Geerling JC, Shin JW, Chimenti PC, Loewy AD (2010) Paraventricular hypothalamic nucleus: axonal projections to the brainstem. J Comp Neurol 518:1460\u20131499","journal-title":"J Comp Neurol"},{"key":"502_CR12","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1038\/nrn1902","volume":"7","author":"PG Guyenet","year":"2006","unstructured":"Guyenet PG (2006) The sympathetic control of blood pressure. Nat Rev Neurosci 7:335\u2013346","journal-title":"Nat Rev Neurosci"},{"key":"502_CR13","doi-asserted-by":"publisher","first-page":"1963","DOI":"10.1007\/s10072-013-1420-y","volume":"34","author":"JM Hong","year":"2013","unstructured":"Hong JM, Kim TJ, Shin DH, Lee JS, Joo IS (2013) Cardiovascular autonomic function in lateral medullary infarction. Neurol Sci 34:1963\u20131969","journal-title":"Neurol Sci"},{"key":"502_CR14","first-page":"63","volume":"24","author":"CT Huang","year":"2015","unstructured":"Huang CT, Lo CP, Chen YC, Tu MC (2015) A rare case of painful trigeminal neuropathy secondary to lateral medullary infarct: neuroimaging and electrophysiological studies. Acta Neurol Taiwan 24:63\u201368","journal-title":"Acta Neurol Taiwan"},{"key":"502_CR15","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1186\/s10194-016-0604-2","volume":"17","author":"D Jin","year":"2016","unstructured":"Jin D, Lian YJ, Zhang HF (2016) Secondary SUNCT syndrome caused by dorsolateral medullary infarction. J Headache Pain 17:12","journal-title":"J Headache Pain"},{"key":"502_CR16","doi-asserted-by":"publisher","first-page":"694","DOI":"10.1161\/01.STR.0000117570.41153.35","volume":"35","author":"W Kameda","year":"2004","unstructured":"Kameda W, Kawanami T, Kurita K, Daimon M, Kayama T, Hosoya T, Kato T, Study Group of the Association of Cerebrovascular Disease in T (2004) Lateral and medial medullary infarction: a comparative analysis of 214 patients. Stroke 35:694\u2013699","journal-title":"Stroke"},{"key":"502_CR17","doi-asserted-by":"publisher","first-page":"1230","DOI":"10.1212\/WNL.57.7.1230","volume":"57","author":"JS Kim","year":"2001","unstructured":"Kim JS (2001) Sensory symptoms in ipsilateral limbs\/body due to lateral medullary infarction. Neurology 57:1230\u20131234","journal-title":"Neurology"},{"key":"502_CR18","doi-asserted-by":"publisher","first-page":"1864","DOI":"10.1093\/brain\/awg169","volume":"126","author":"JS Kim","year":"2003","unstructured":"Kim JS (2003) Pure lateral medullary infarction: clinical-radiological correlation of 130 acute, consecutive patients. Brain 126:1864\u20131872","journal-title":"Brain"},{"key":"502_CR19","doi-asserted-by":"publisher","first-page":"3221","DOI":"10.1161\/STROKEAHA.109.559864","volume":"40","author":"JS Kim","year":"2009","unstructured":"Kim JS, Han YS (2009) Medial medullary infarction: clinical, imaging, and outcome study in 86 consecutive patients. Stroke 40:3221\u20133225","journal-title":"Stroke"},{"key":"502_CR20","doi-asserted-by":"publisher","first-page":"1548","DOI":"10.1161\/01.STR.26.9.1548","volume":"26","author":"JS Kim","year":"1995","unstructured":"Kim JS, Kim HG, Chung CS (1995) Medial medullary syndrome. Report of 18 new patients and a review of the literature. Stroke 26:1548\u20131552","journal-title":"Stroke"},{"key":"502_CR21","doi-asserted-by":"publisher","first-page":"1405","DOI":"10.1161\/01.STR.25.7.1405","volume":"25","author":"JS Kim","year":"1994","unstructured":"Kim JS, Lee JH, Suh DC, Lee MC (1994) Spectrum of lateral medullary syndrome\u2014correlation between clinical findings and magnetic-resonance-imaging in 33 subjects. Stroke 25:1405\u20131410","journal-title":"Stroke"},{"key":"502_CR22","doi-asserted-by":"publisher","first-page":"116","DOI":"10.3988\/jcn.2012.8.2.116","volume":"8","author":"K Kim","year":"2012","unstructured":"Kim K, Lee HS, Jung YH, Kim YD, Nam HS, Nam CM, Kim SM, Heo JH (2012) Mechanism of medullary infarction based on arterial territory involvement. J Clin Neurol 8:116\u2013122","journal-title":"J Clin Neurol"},{"issue":"feb04 1","key":"502_CR23","doi-asserted-by":"publisher","first-page":"bcr2012007783","DOI":"10.1136\/bcr-2012-007783","volume":"2013","author":"S. Koay","year":"2013","unstructured":"Koay S, Dewan B (2013) An unexpected Holter monitor result: multiple sinus arrests in a patient with lateral medullary syndrome. BMJ Case Rep 2013. \n                    https:\/\/doi.org\/10.1136\/bcr-2012-007783","journal-title":"Case Reports"},{"key":"502_CR24","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1161\/01.STR.25.4.787","volume":"25","author":"JT Korpelainen","year":"1994","unstructured":"Korpelainen JT, Sotaniemi KA, Suominen K, Tolonen U, Myllyla VV (1994) Cardiovascular autonomic reflexes in brain infarction. Stroke 25:787\u2013792","journal-title":"Stroke"},{"key":"502_CR25","doi-asserted-by":"publisher","first-page":"1286","DOI":"10.1001\/archneur.62.8.1286","volume":"62","author":"AB Lassman","year":"2005","unstructured":"Lassman AB, Mayer SA (2005) Paroxysmal apnea and vasomotor instability following medullary infarction. Arch Neurol 62:1286\u20131288","journal-title":"Arch Neurol"},{"key":"502_CR26","doi-asserted-by":"publisher","first-page":"773","DOI":"10.1179\/016164102101200870","volume":"24","author":"H Lee","year":"2002","unstructured":"Lee H, Sohn CH (2002) Axial lateropulsion as a sole manifestation of lateral medullary infarction: a clinical variant related to rostral-dorsolateral lesion. Neurol Res 24:773\u2013774","journal-title":"Neurol Res"},{"key":"502_CR27","doi-asserted-by":"publisher","first-page":"1433","DOI":"10.1111\/j.1468-1331.2012.03722.x","volume":"19","author":"MJ Lee","year":"2012","unstructured":"Lee MJ, Park YG, Kim SJ, Lee JJ, Bang OY, Kim JS (2012) Characteristics of stroke mechanisms in patients with medullary infarction. Eur J Neurol 19:1433\u20131439","journal-title":"Eur J Neurol"},{"key":"502_CR28","doi-asserted-by":"publisher","first-page":"R364","DOI":"10.1152\/ajpregu.2000.279.2.R364","volume":"279","author":"M Natarajan","year":"2000","unstructured":"Natarajan M, Morrison SF (2000) Sympathoexcitatory CVLM neurons mediate responses to caudal pressor area stimulation. Am J Physiol Regul Integr Comp Physiol 279:R364\u2013R374","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"502_CR29","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1212\/WNL.0000000000000605","volume":"83","author":"JA Palma","year":"2014","unstructured":"Palma JA, Benarroch EE (2014) Neural control of the heart: recent concepts and clinical correlations. Neurology 83:261\u2013271","journal-title":"Neurology"},{"key":"502_CR30","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1016\/j.jstrokecerebrovasdis.2008.02.007","volume":"17","author":"JH Park","year":"2008","unstructured":"Park JH, Yoo HU, Shin HW (2008) Peripheral type facial palsy in a patient with dorsolateral medullary infarction with infranuclear involvement of the caudal pons. J Stroke Cerebrovasc Dis 17:263\u2013265","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"502_CR31","doi-asserted-by":"publisher","first-page":"1997","DOI":"10.1161\/01.STR.31.8.1997","volume":"31","author":"AM Phillips","year":"2000","unstructured":"Phillips AM, Jardine DL, Parkin PJ, Hughes T, Ikram H (2000) Brain stem stroke causing baroreflex failure and paroxysmal hypertension. Stroke 31:1997\u20132001","journal-title":"Stroke"},{"key":"502_CR32","doi-asserted-by":"publisher","first-page":"1675","DOI":"10.1097\/00004872-200209000-00002","volume":"20","author":"PM Pilowsky","year":"2002","unstructured":"Pilowsky PM, Goodchild AK (2002) Baroreceptor reflex pathways and neurotransmitters: 10\u00a0years on. J Hypertens 20:1675\u20131688","journal-title":"J Hypertens"},{"key":"502_CR33","first-page":"297","volume":"64","author":"M Planjar-Prvan","year":"2010","unstructured":"Planjar-Prvan M, Krmpotic P, Jergovic I, Bielen I (2010) Central sleep apnea (Ondine\u2019s curse syndrome) in medullary infarction. Acta Med Croatica 64:297\u2013301","journal-title":"Acta Med Croatica"},{"key":"502_CR34","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1016\/0006-8993(76)90738-1","volume":"117","author":"CB Saper","year":"1976","unstructured":"Saper CB, Loewy AD, Swanson LW, Cowan WM (1976) Direct hypothalamo-autonomic connections. Brain Res 117:305\u2013312","journal-title":"Brain Res"},{"key":"502_CR35","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1159\/000319887","volume":"30","author":"Y Shono","year":"2010","unstructured":"Shono Y, Koga M, Toyoda K, Matsuoka H, Yokota C, Uehara T, Yamamoto H, Minematsu K (2010) Medial medullary infarction identified by diffusion-weighted magnetic resonance imaging. Cerebrovasc Dis 30:519\u2013524","journal-title":"Cerebrovasc Dis"},{"key":"502_CR36","doi-asserted-by":"publisher","first-page":"R768","DOI":"10.1152\/ajpregu.00184.2002","volume":"283","author":"W Sun","year":"2002","unstructured":"Sun W, Panneton WM (2002) The caudal pressor area of the rat: its precise location and projections to the ventrolateral medulla. Am J Physiol Regul Integr Comp Physiol 283:R768\u2013R778","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"502_CR37","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1159\/000317105","volume":"30","author":"M Sykora","year":"2010","unstructured":"Sykora M, Diedler J, Poli S, Rupp A, Turcani P, Steiner T (2010) Blood pressure course in acute stroke relates to baroreflex dysfunction. Cerebrovasc Dis 30:172\u2013179","journal-title":"Cerebrovasc Dis"},{"key":"502_CR38","doi-asserted-by":"publisher","first-page":"716","DOI":"10.1212\/01.WNL.0000152040.27264.1A","volume":"64","author":"F Thomke","year":"2005","unstructured":"Thomke F, Marx JJ, Iannetti GD, Cruccu G, Fitzek S, Urban PP, Stoeter P, Dieterich M, Hopf HC (2005) A topodiagnostic investigation on body lateropulsion in medullary infarcts. Neurology 64:716\u2013718","journal-title":"Neurology"},{"key":"502_CR39","doi-asserted-by":"publisher","first-page":"1903","DOI":"10.1016\/j.jstrokecerebrovasdis.2014.02.010","volume":"23","author":"Y Tsuyusaki","year":"2014","unstructured":"Tsuyusaki Y, Sakakibara R, Kishi M, Tateno F, Aiba Y, Ogata T, Nagao T, Terada H, Inaoka T (2014) \u201cInvisible\u201d brain stem infarction at the first day. J Stroke Cerebrovasc Dis 23:1903\u20131907","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"502_CR40","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1007\/BF02680179","volume":"34","author":"A Wallenberg","year":"1901","unstructured":"Wallenberg A (1901) Anatomischer Befund in einem als \u201cacute Bulb\u00e4raffection (Embolie der Art. cerebellar. post. inf. sinistr.?)\u201d1) beschriebenen Falle. Archiv Psychiatr Nervenkr 34:923\u2013959","journal-title":"Archiv Psychiatr Nervenkr"},{"key":"502_CR41","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1186\/s12883-014-0231-y","volume":"14","author":"S Wu","year":"2014","unstructured":"Wu S, Li N, Xia F, Sidlauskas K, Lin X, Qian Y, Gao W, Zhang Q (2014) Neurotrophic keratopathy due to dorsolateral medullary infarction (Wallenberg syndrome): case report and literature review. BMC Neurol 14:231","journal-title":"BMC Neurol"}],"container-title":["Clinical Autonomic Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10286-018-0502-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10286-018-0502-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10286-018-0502-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,1,24]],"date-time":"2019-01-24T14:35:01Z","timestamp":1548340501000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10286-018-0502-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1,24]]},"references-count":41,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2018,12]]}},"alternative-id":["502"],"URL":"https:\/\/doi.org\/10.1007\/s10286-018-0502-6","relation":{},"ISSN":["0959-9851","1619-1560"],"issn-type":[{"value":"0959-9851","type":"print"},{"value":"1619-1560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,1,24]]},"assertion":[{"value":"30 June 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 January 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 January 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declared that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The manuscript does not contain clinical studies or patient data.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Human and animal rights"}}]}}