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CM reports consultancies with Acorda Therapeutics; honoraria for teaching from EMD Serono, steering committee for Michael J. Fox Foundation; grants from the Michael J. Fox Foundation, Canadian Institutes of Health Research, International Parkinson and Movement Disorder Society, and National Institutes of Health Research; and employment with University Health Network. NPV reports none. DJC reports none. LS reports none. BS reports none. SMG reports employment with the University of California-San Francisco, San Francisco Veterans Affairs Health Care System, and grants from the Michael J. Fox Foundation, National Institute for Occupational Safety and Health (NIOSH), Biogen, and the U.S. Department of Defense. ME reports none. PKS reports none. AEL has served as an advisor for Abbvie, Acorda, Biogen, Bristol-Myers Squibb, Janssen, Sun Pharma, Kallyope, Merck, Paladin, and Corticobasal Degeneration Solutions; received honoraria from Sun Pharma, Medichem, Medtronic, AbbVie and Sunovion; received grants from Brain Canada, Canadian Institutes of Health Research, Corticobasal Degeneration Solutions, Edmond J. Safra Philanthropic Foundation, Michael J. Fox Foundation, the Ontario Brain Institute, National Parkinson Foundation, Parkinson Society Canada, and W. Garfield Weston Foundation; received publishing royalties from Elsevier, Saunders, Wiley-Blackwell, Johns Hopkins Press, and Cambridge University Press. HFJ reports none. AM reports employment with Universidad de La Habana.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The study protocol was approved by the University Health Network Research Ethics Board (Toronto) and El Camino Hospital Institutional Review Board (Parkinson\u2019s Institute). The study was performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical standards"}},{"value":"All participants provided written informed consent prior to their inclusion in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}