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Joana Schauermann, Svenja H\u00fcsch: none. Bruno Fimm: grants: Institute for Statutory Accident Insurance and Prevention in the Energy, Textile, Electrical, and Media Industry (BGETEM). Christina Haubrich: grants: ParkinsonFonds International Kathrin Reetz: grants: German Federal Ministry of Education and Research (BMBF 01GQ1402, 01DN18022), German Research Foundation (IRTG 2150, ZUK32\/1), Alzheimer Forschung Initiative e.V. (AFI 13812, NL-18002CB); honoraria\/advisory boards: Lilly, Roche; clinical trial grants: Pfizer, Merck, Minoryx, Biogen, Roche. J\u00f6rg B. Schulz: Advisory Board: Biogen, Grifols, Novartis; grant: German Research Foundation, German Ministry of Research and Education. Andrea Maier: Advisory Board: Deutsche EDS Initiative, Deutsche Ehlers-Danlos Selbsthilfe, PoTS und andere Dysautonomien; grants: Takeda Pharmaceuticas, Standing Up to POTS Research Fund, Centogene GmbH.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The study was approved by the local ethics committee (EK 060\/14), registered at clinical trials.gov (NCT03900000), and conducted under the principles of the Declaration of Helsinki. All patients gave written informed consent prior to enrollment.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}