{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T22:22:50Z","timestamp":1782944570503,"version":"3.54.5"},"reference-count":61,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,10,17]],"date-time":"2024-10-17T00:00:00Z","timestamp":1729123200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,10,17]],"date-time":"2024-10-17T00:00:00Z","timestamp":1729123200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100014440","name":"Ministerio de Ciencia, Innovaci\u00f3n y Universidades","doi-asserted-by":"publisher","award":["PID2022-139731OB-I00"],"award-info":[{"award-number":["PID2022-139731OB-I00"]}],"id":[{"id":"10.13039\/100014440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007064","name":"Universidad de Ja\u00e9n","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100007064","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin. Auton. Res."],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Alterations of autonomic cardiovascular control are implicated in the origin of chronic low blood pressure (BP) (hypotension), but comprehensive analysis of baroreflex function is still lacking. This study explored baroreflex function in its cardiac, vascular and myocardial branches<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Continuous BP was recorded at rest and during a mental arithmetic task in 40 hypotensive and 40 normotensive participants. Assessed cardiovascular variables included stroke volume (SV) (calculated by the Modelflow method), heart rate (HR), cardiac output (CO), total peripheral resistance (TPR) and heart rate variability (HRV). Baroreflex sensitivity (BRS) was calculated using the spontaneous sequence method.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Hypotensive participants exhibited greater BRS in the three baroreflex branches, in addition to lower SV, HR and CO and higher HRV and TPR. Reactivity for BP, HRV and CO during the stress task was reduced in hypotensive individuals. The greater cardiac BRS can explain the lower HR and higher HRV observed in hypotension, suggestive of increased vagal cardiac influences. The higher vasomotor BRS may contribute to the greater TPR observed in the hypotensive participants. Abnormal associations between myocardial BRS and SV arose, suggesting aberrant autonomic control of myocardial contractility in hypotension.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The results indicate that hemodynamic deficits in hypotension are related to preload factors, probably triggered by hypovolemia and reduced unstressed blood reserves, resulting in lower venous return, ventricular preload and SV. In contrast, afterload mechanisms seem to work appropriately.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s10286-024-01076-7","type":"journal-article","created":{"date-parts":[[2024,10,17]],"date-time":"2024-10-17T07:02:16Z","timestamp":1729148536000},"page":"87-99","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The cardiac, vasomotor and myocardial branches of the baroreflex in hypotension: indications of reduced venous return to the heart"],"prefix":"10.1007","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2188-8673","authenticated-orcid":false,"given":"Gustavo A.","family":"Reyes del Paso","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Casandra I.","family":"Montoro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dmitry M.","family":"Davydov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Duschek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,10,17]]},"reference":[{"key":"1076_CR1","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1023\/A:1007729229483","volume":"12","author":"M De Buyzere","year":"1998","unstructured":"De Buyzere M, Clement DL, Duprez D (1998) Chronic low blood pressure: a review. Cardiovasc Drugs Ther 12:29\u201335","journal-title":"Cardiovasc Drugs Ther"},{"key":"1076_CR2","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1007\/s10286-011-0119-5","volume":"21","author":"R Freeman","year":"2011","unstructured":"Freeman R, Wieling W, Axelrod FB et al (2011) Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome. Clin Auton Res 21:69\u201372","journal-title":"Clin Auton Res"},{"key":"1076_CR3","doi-asserted-by":"publisher","first-page":"767","DOI":"10.1111\/psyp.12055","volume":"50","author":"N Covassin","year":"2013","unstructured":"Covassin N, de Zambotti M, Cellini N, Sarlo M, Stegagno L (2013) Cardiovascular down-regulation in essential hypotension: relationships with autonomic control and sleep. Psychophysiology 50:767\u2013776","journal-title":"Psychophysiology"},{"key":"1076_CR4","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1016\/j.ijpsycho.2012.05.002","volume":"85","author":"M De Zambotti","year":"2012","unstructured":"De Zambotti M, Covassin N, Cellini N, Sarlo M, Stegagno L (2012) Cardiac autonomic profile during rest and working memory load in essential hypotensive women. Int J Psychophysiol 85:200\u2013205","journal-title":"Int J Psychophysiol"},{"key":"1076_CR5","doi-asserted-by":"publisher","first-page":"442","DOI":"10.1007\/s12160-016-9868-7","volume":"51","author":"S Duschek","year":"2017","unstructured":"Duschek S, Hoffmann A, Reyes del Paso GA, Ettinger U (2017) Autonomic cardiovascular control and executive function in chronic hypotension. Ann Behav Med 51:442\u2013453","journal-title":"Ann Behav Med"},{"key":"1076_CR6","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1007\/s10865-012-9410-8","volume":"36","author":"M Sarlo","year":"2013","unstructured":"Sarlo M, de Zambotti M, Gallicchio G, Devigili A, Stegagno L (2013) Impaired cerebral and systemic hemodynamics under cognitive load in young hypotensives: a transcranial doppler study. J Behav Med 36:134\u2013142","journal-title":"J Behav Med"},{"key":"1076_CR7","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/j.jpsychores.2016.12.008","volume":"93","author":"S Duschek","year":"2017","unstructured":"Duschek S, Hoffmann A, Reyes del Paso GA (2017) Affective impairment in chronic low blood pressure. J Psychosom Res 93:33\u201340","journal-title":"J Psychosom Res"},{"key":"1076_CR8","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1016\/j.biopsycho.2005.06.011","volume":"72","author":"S Duschek","year":"2006","unstructured":"Duschek S, Meinhardt J, Schandry R (2006) Reduced cortical activity due to chronic low blood pressure: an EEG study. Biol Psychol 72:241\u2013250","journal-title":"Biol Psychol"},{"key":"1076_CR9","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1016\/j.biopsycho.2005.12.003","volume":"72","author":"S Duschek","year":"2006","unstructured":"Duschek S, Schandry R (2006) Deficient adjustment of cerebral blood flow to cognitive activity due to chronically low blood pressure. Biol Psychol 72:311\u2013317","journal-title":"Biol Psychol"},{"key":"1076_CR10","doi-asserted-by":"publisher","first-page":"905","DOI":"10.1111\/j.1469-8986.2004.00249.x","volume":"41","author":"S Duschek","year":"2004","unstructured":"Duschek S, Schandry R (2004) Cognitive performance and cerebral blood flow in essential hypotension. Psychophysiology 41:905\u2013913","journal-title":"Psychophysiology"},{"key":"1076_CR11","doi-asserted-by":"publisher","unstructured":"Duschek S, Heiss H, Buechner B, Werner N, Schandry R, Reyes del Paso GA (2009) Hemodynamic determinants of chronic hypotension and their modification through vasopressor application. J Physiol Sci 59(2):105-112 https:\/\/doi.org\/10.1007\/s12576-008-0015-5","DOI":"10.1007\/s12576-008-0015-5"},{"key":"1076_CR12","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1007\/s10286-006-0379-7","volume":"17","author":"S Duschek","year":"2007","unstructured":"Duschek S, Schandry R (2007) Reduced brain perfusion and cognitive performance due to constitutional hypotension. Clin Auton Res 17:69\u201376","journal-title":"Clin Auton Res"},{"key":"1076_CR13","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1027\/0269-8803\/a000204","volume":"33","author":"S Duschek","year":"2019","unstructured":"Duschek S, Hoffmann A, Montoro CI, Reyes del Paso GA (2019) Autonomic cardiovascular dysregulation at rest and during stress in chronically low blood pressure. J Psychophysiol 33:39\u201353","journal-title":"J Psychophysiol"},{"key":"1076_CR14","doi-asserted-by":"publisher","first-page":"952","DOI":"10.1097\/PSY.0b013e318272db69","volume":"74","author":"N Covassin","year":"2012","unstructured":"Covassin N, de Zambotti M, Cellini N, Sarlo M, Stegagno L (2012) Nocturnal cardiovascular activity in essential hypotension: evidence of differential autonomic regulation. Psychosom Med 74:952\u2013960","journal-title":"Psychosom Med"},{"key":"1076_CR15","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1016\/j.biopsycho.2012.05.009","volume":"91","author":"M De Zambotti","year":"2012","unstructured":"De Zambotti M, Covassin N, Cellini N, Sarlo M, Torre J, Stegagno L (2012) Hemodynamic and autonomic modifications during sleep stages in young hypotensive women. Biol Psychol 91:22\u201327","journal-title":"Biol Psychol"},{"key":"1076_CR16","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1093\/eurheartj\/13.suppl_E.7","volume":"13","author":"R Jacob","year":"1992","unstructured":"Jacob R, Dierberger B, Kissling G (1992) Functional significance of the Frank-Starling mechanism under physiological and pathophysiological conditions. Eur Heart J 13:7\u201314","journal-title":"Eur Heart J"},{"key":"1076_CR17","unstructured":"Hall JE, Hall ME (2020) Guyton and Hall textbook of medical physiology. Saunders Elsevier, Philadelphia"},{"key":"1076_CR18","doi-asserted-by":"crossref","unstructured":"Berntson GG, Quigley KS, Norman GJ, Lozano DL (2016) In: Cacioppo JT, Tassinary LG, Berntson G (eds) Cardiovascular psychophysiology. In: Handbook of psychophysiology. Cambridge University Press, Cambridge, pp 183\u2013216","DOI":"10.1017\/9781107415782.009"},{"key":"1076_CR19","doi-asserted-by":"publisher","first-page":"477","DOI":"10.1111\/psyp.12027","volume":"50","author":"GA Reyes del Paso","year":"2013","unstructured":"Reyes del Paso GA, Langewitz W, Mulder LJM, van Roon A, Duschek S (2013) The utility of low frequency heart rate variability as an index of sympathetic cardiac tone: a review with emphasis on a reanalysis of previous studies. Psychophysiology 50:477\u2013487","journal-title":"Psychophysiology"},{"key":"1076_CR20","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1016\/0167-8760(96)00020-7","volume":"22","author":"GA Reyes del Paso","year":"1996","unstructured":"Reyes del Paso GA, Langewitz W, Robles H, P\u00e9rez N (1996) A between-subjects comparison of respiratory sinus arrhythmia and baroreceptor cardiac reflex sensitivity as non-invasive measures of tonic parasympathetic cardiac control. Int J Psychophysiol 22:163\u2013171","journal-title":"Int J Psychophysiol"},{"key":"1076_CR21","doi-asserted-by":"publisher","first-page":"1873","DOI":"10.1291\/hypres.31.1873","volume":"31","author":"S Duschek","year":"2008","unstructured":"Duschek S, Dietel A, Schandry R, Reyes Del Paso GA (2008) Increased baroreflex sensitivity and reduced cardiovascular reactivity in individuals with chronic low blood pressure. Hypertens Res 31:1873\u20131878","journal-title":"Hypertens Res"},{"key":"1076_CR22","doi-asserted-by":"publisher","first-page":"1183","DOI":"10.1111\/psyp.12136","volume":"50","author":"S Duschek","year":"2013","unstructured":"Duschek S, Werner NS, Reyes del Paso GA (2013) The behavioral impact of baroreflex function: a review. Psychophysiology 50:1183\u20131193","journal-title":"Psychophysiology"},{"key":"1076_CR23","doi-asserted-by":"publisher","first-page":"1528","DOI":"10.1111\/psyp.12898","volume":"54","author":"GA Reyes del Paso","year":"2017","unstructured":"Reyes del Paso GA, de la Coba P, Mart\u00edn-V\u00e1zquez M, Thayer JF (2017) Time domain measurement of the vascular and myocardial branches of the baroreflex: a study in physically active versus sedentary individuals. Psychophysiology 54:1528\u20131540","journal-title":"Psychophysiology"},{"key":"1076_CR24","first-page":"S79","volume":"3","author":"G Bertinieri","year":"1985","unstructured":"Bertinieri G, di Rienzo M, Cavallazzi A, Ferrari AU, Pedotti A, Mancia G (1985) A new approach to analysis of the arterial baroreflex. J Hypertens Suppl 3:S79-81","journal-title":"J Hypertens Suppl"},{"key":"1076_CR25","doi-asserted-by":"publisher","first-page":"627","DOI":"10.1093\/cvr\/24.8.627","volume":"24","author":"A Steptoe","year":"1990","unstructured":"Steptoe A, Vogele C (1990) Cardiac baroreflex function during postural change assessed using non-invasive spontaneous sequence analysis in young men. Cardiovasc Res 24:627\u2013632","journal-title":"Cardiovasc Res"},{"key":"1076_CR26","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1016\/j.amsu.2013.11.002","volume":"3","author":"ER Carthy","year":"2014","unstructured":"Carthy ER (2014) Autonomic dysfunction in essential hypertension: a systematic review. Ann Med Surg (Lond) 3:2\u20137","journal-title":"Ann Med Surg (Lond)"},{"key":"1076_CR27","first-page":"148","volume":"30","author":"TE Lohmeier","year":"2015","unstructured":"Lohmeier TE, Iliescu R (2015) The baroreflex as a long-term controller of arterial pressure. Physiology (Bethesda) 30:148\u2013158","journal-title":"Physiology (Bethesda)"},{"key":"1076_CR28","doi-asserted-by":"publisher","first-page":"259","DOI":"10.2170\/physiolsci.RP008807","volume":"57","author":"S Duschek","year":"2007","unstructured":"Duschek S, Reyes del Paso GA (2007) Quantification of cardiac baroreflex function at rest and during autonomic stimulation. J Physiol Sci 57:259\u2013268","journal-title":"J Physiol Sci"},{"key":"1076_CR29","doi-asserted-by":"publisher","first-page":"775","DOI":"10.1016\/j.amjhyper.2005.07.019","volume":"19","author":"M Ducher","year":"2006","unstructured":"Ducher M, Fauvel J, Cerutti C (2006) Risk profile in hypertension genesis: a five-year follow-up study. Am J Hypertens 19:775\u2013780","journal-title":"Am J Hypertens"},{"key":"1076_CR30","doi-asserted-by":"publisher","first-page":"852","DOI":"10.1097\/PSY.0b013e3181b8bb7a","volume":"71","author":"M Koschke","year":"2009","unstructured":"Koschke M, Boettger MK, Schulz S, Berger S, Terhaar J, Voss A, Yeragani VK, B\u00e4r K-J (2009) Autonomy of autonomic dysfunction in major depression. Psychosom Med 71:852\u2013860","journal-title":"Psychosom Med"},{"issue":"5","key":"1076_CR31","doi-asserted-by":"publisher","DOI":"10.1111\/psyp.13800","volume":"58","author":"GA Reyes del Paso","year":"2021","unstructured":"Reyes del Paso GA, Contreras-Merino AM, de la Coba P, Duschek S (2021) The cardiac, vasomotor, and myocardial branches of the baroreflex in fibromyalgia: associations with pain, affective impairments, sleep problems, and fatigue. Psychophysiology 58(5):e13800","journal-title":"Psychophysiology"},{"key":"1076_CR32","doi-asserted-by":"publisher","first-page":"R744","DOI":"10.1152\/ajpregu.2001.280.3.R744","volume":"280","author":"M Di Rienzo","year":"2001","unstructured":"Di Rienzo M, Parati G, Castiglioni P, Tordi R, Mancia G, Pedotti A (2001) Baroreflex effectiveness index: an additional measure of baroreflex control of heart rate in daily life. Am J Physiol Regul Integr Comp Physiol 280:R744\u2013R751","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"1076_CR33","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/j.ijpsycho.2005.02.006","volume":"59","author":"GA Reyes del Paso","year":"2006","unstructured":"Reyes del Paso GA, Hern\u00e1ndez JA, Gonz\u00e1lez MI (2006) Differential evaluation of the baroreceptor cardiac reflex effectiveness as a function of sequence length. Int J Psychophysiol 59:91\u201396","journal-title":"Int J Psychophysiol"},{"key":"1076_CR34","doi-asserted-by":"publisher","first-page":"149","DOI":"10.3200\/BMED.30.4.149-160","volume":"30","author":"S Duschek","year":"2005","unstructured":"Duschek S, Matthia E, Schandry R (2005) Essential hypotension is accompanied by deficits in attention and working memory. Behav Med 30:149\u2013160","journal-title":"Behav Med"},{"key":"1076_CR35","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1016\/j.bandc.2018.06.008","volume":"125","author":"S Duschek","year":"2018","unstructured":"Duschek S, Hoffmann A, Bair A, Reyes Del Paso GA, Montoro CI (2018) Cerebral blood flow modulations during proactive control in chronic hypotension. Brain Cogn 125:135\u2013141","journal-title":"Brain Cogn"},{"key":"1076_CR36","doi-asserted-by":"publisher","DOI":"10.1111\/psyp.13305","volume":"56","author":"S Duschek","year":"2019","unstructured":"Duschek S, Hoffmann A, Montoro CI, Bair A, Reyes Del Paso GA, Ettinger U (2019) Cerebral blood flow modulations during antisaccade preparation in chronic hypotension. Psychophysiology 56:e13305","journal-title":"Psychophysiology"},{"key":"1076_CR37","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1111\/j.1469-8986.2007.00507.x","volume":"44","author":"L Stegagno","year":"2007","unstructured":"Stegagno L, Patritti D, Duschek S, Herbert B, Schandry R (2007) Cerebral blood flow in essential hypotension during emotional activation. Psychophysiology 44:226\u2013232","journal-title":"Psychophysiology"},{"key":"1076_CR38","doi-asserted-by":"publisher","first-page":"737","DOI":"10.1111\/1469-8986.3560737","volume":"35","author":"M Costa","year":"1998","unstructured":"Costa M, Stegagno L, Schandry R, Bitti PER (1998) Contingent negative variation and cognitive performance in hypotension. Psychophysiology 35:737\u2013744","journal-title":"Psychophysiology"},{"key":"1076_CR39","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1016\/S0167-8760(02)00032-6","volume":"45","author":"N Weisz","year":"2002","unstructured":"Weisz N, Schandry R, Jacobs AM, Mialet J-P, Duschek S (2002) Early contingent negative variation of the EEG and attentional flexibility are reduced in hypotension. Int J Psychophysiol 45:253\u2013260","journal-title":"Int J Psychophysiol"},{"key":"1076_CR40","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1016\/j.ejpain.2008.02.007","volume":"13","author":"S Duschek","year":"2009","unstructured":"Duschek S, Dietel A, Schandry R, del Paso GAR (2009) Increased sensitivity to heat pain in chronic low blood pressure. Eur J Pain 13:28\u201334","journal-title":"Eur J Pain"},{"key":"1076_CR41","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1027\/0269-8803.23.3.104","volume":"23","author":"S Duschek","year":"2009","unstructured":"Duschek S, Heiss H, Buechner B, Schandry R (2009) Reduction in pain sensitivity from pharmacological elevation of blood pressure in persons with chronically low blood pressure. J Psychophysiol 23:104\u2013112","journal-title":"J Psychophysiol"},{"key":"1076_CR42","doi-asserted-by":"publisher","first-page":"938","DOI":"10.1038\/hr.2009.115","volume":"32","author":"S Duschek","year":"2009","unstructured":"Duschek S, Heiss H, Werner N, Reyes del Paso GA (2009) Modulations of autonomic cardiovascular control following acute alpha-adrenergic treatment in chronic hypotension. Hypertens Res 32:938\u2013943","journal-title":"Hypertens Res"},{"key":"1076_CR43","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1111\/j.1469-8986.2006.00472.x","volume":"44","author":"S Duschek","year":"2007","unstructured":"Duschek S, Hadjamu M, Schandry R (2007) Enhancement of cerebral blood flow and cognitive performance following pharmacological blood pressure elevation in chronic hypotension. Psychophysiology 44:145\u2013153","journal-title":"Psychophysiology"},{"key":"1076_CR44","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1016\/j.biopsycho.2007.03.007","volume":"75","author":"S Duschek","year":"2007","unstructured":"Duschek S, Hadjamu M, Schandry R (2007) Dissociation between cortical activation and cognitive performance under pharmacological blood pressure elevation in chronic hypotension. Biol Psychol 75:277\u2013285","journal-title":"Biol Psychol"},{"key":"1076_CR45","first-page":"67","volume":"36","author":"KH Wesseling","year":"1995","unstructured":"Wesseling KH, De Wit B, Van Der Hoeven GMA, Van Goudoever J, Settels JJ (1995) Physiocal, calibrating finger vascular physiology for Finapres. Homeostasis 36:67\u201382","journal-title":"Homeostasis"},{"key":"1076_CR46","doi-asserted-by":"publisher","first-page":"2566","DOI":"10.1152\/jappl.1993.74.5.2566","volume":"74","author":"KH Wesseling","year":"1993","unstructured":"Wesseling KH, Jansen JR, Settels JJ, Schreuder JJ (1993) Computation of aortic flow from pressure in humans using a nonlinear, three-element model. J Appl Physiol 74:2566\u20132573","journal-title":"J Appl Physiol"},{"key":"1076_CR47","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1113\/expphysiol.2005.030262","volume":"90","author":"LWJ Bogert","year":"2005","unstructured":"Bogert LWJ, van Lieshout JJ (2005) Non-invasive pulsatile arterial pressure and stroke volume changes from the human finger. Exp Physiol 90:437\u2013446","journal-title":"Exp Physiol"},{"key":"1076_CR48","doi-asserted-by":"publisher","first-page":"1317","DOI":"10.1097\/00000542-199905000-00016","volume":"90","author":"WT Jellema","year":"1999","unstructured":"Jellema WT, Wesseling KH, Groeneveld AB, Stoutenbeek CP, Thijs LG, van Lieshout JJ (1999) Continuous cardiac output in septic shock by simulating a model of the aortic input impedance: a comparison with bolus injection thermodilution. Anesthesiology 90:1317\u20131328","journal-title":"Anesthesiology"},{"key":"1076_CR49","first-page":"935","volume":"76","author":"DF Doerr","year":"2005","unstructured":"Doerr DF, Ratliff DA, Sithole J, Convertino VA (2005) Stroke volume during orthostatic challenge: comparison of two non-invasive methods. Aviat Space Environ Med 76:935\u2013939","journal-title":"Aviat Space Environ Med"},{"key":"1076_CR50","doi-asserted-by":"publisher","first-page":"464","DOI":"10.3758\/BF03203582","volume":"24","author":"GA Reyes del Paso","year":"1992","unstructured":"Reyes del Paso GA (1992) An on-line program to calculate respiratory sinus arrhythmia amplitude. Behav Res Methods Instrum Comput 24:464\u2013466","journal-title":"Behav Res Methods Instrum Comput"},{"key":"1076_CR51","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1097\/00004872-200018010-00003","volume":"18","author":"G Parati","year":"2000","unstructured":"Parati G, Di Rienzo M, Mancia G (2000) How to measure baroreflex sensitivity: from the cardiovascular laboratory to daily life. J Hypertens 18:7\u201319","journal-title":"J Hypertens"},{"key":"1076_CR52","first-page":"1102","volume":"47","author":"GAR Reyes del Paso","year":"2010","unstructured":"Reyes del Paso GAR, Gonz\u00e1lez MI, Hern\u00e1ndez JA (2010) Comparison of baroreceptor cardiac reflex sensitivity estimates from inter-systolic and ECG R-R intervals. Psychophysiology 47:1102\u20131108","journal-title":"Psychophysiology"},{"key":"1076_CR53","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1097\/00001648-199001000-00010","volume":"1","author":"KJ Rothman","year":"1990","unstructured":"Rothman KJ (1990) No adjustments are needed for multiple comparisons. Epidemiology 1:43\u201346","journal-title":"Epidemiology"},{"key":"1076_CR54","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1111\/j.1469-8986.2004.00178.x","volume":"41","author":"GA Reyes del Paso","year":"2004","unstructured":"Reyes del Paso GA, Hern\u00e1ndez JA, Gonz\u00e1lez MI (2004) Differential analysis in the time domain of the baroreceptor cardiac reflex sensitivity as a function of sequence length. Psychophysiology 41:483\u2013488","journal-title":"Psychophysiology"},{"key":"1076_CR55","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1016\/j.physbeh.2015.02.047","volume":"143","author":"N Cellini","year":"2015","unstructured":"Cellini N, de Zambotti M, Covassin N, Gallicchio G, Stegagno L, Sarlo M (2015) Reduced cerebral and cardiovascular hemodynamics during sustained affective stimulation in young women with chronic low blood pressure. Physiol Behav 143:83\u201389","journal-title":"Physiol Behav"},{"key":"1076_CR56","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1152\/jappl.1980.49.4.715","volume":"49","author":"ER Nadel","year":"1980","unstructured":"Nadel ER, Fortney SM, Wenger CB (1980) Effect of hydration state of circulatory and thermal regulations. J Appl Physiol 49:715\u2013721","journal-title":"J Appl Physiol"},{"key":"1076_CR57","doi-asserted-by":"publisher","first-page":"1229","DOI":"10.1152\/jappl.1997.82.4.1229","volume":"82","author":"J Gonz\u00e1lez-Alonso","year":"1997","unstructured":"Gonz\u00e1lez-Alonso J, Mora-Rodr\u00edguez R, Below PR, Coyle EF (1997) Dehydration markedly impairs cardiovascular function in hyperthermic endurance athletes during exercise. J Appl Physiol 82:1229\u20131236","journal-title":"J Appl Physiol"},{"key":"1076_CR58","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1186\/s13054-016-1438-7","volume":"20","author":"S Magder","year":"2016","unstructured":"Magder S (2016) Volume and its relationship to cardiac output and venous return. Crit Care 20:271","journal-title":"Crit Care"},{"key":"1076_CR59","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1097\/MNH.0b013e3283641a89","volume":"22","author":"EJ Johns","year":"2013","unstructured":"Johns EJ, Abdulla MH (2013) Renal nerves in blood pressure regulation. Curr Opin Nephrol Hypertens 22:504\u2013510","journal-title":"Curr Opin Nephrol Hypertens"},{"key":"1076_CR60","unstructured":"Klabunde RE (2021) Mechanical factors affecting central venous pressure and venous return: respiratory activity (abdominothoracic or respiratory pump). In: Klabunde RE (ed) Cardiovascular physiology concepts. Alphen aan den Rijn, Wolters Kluwer, pp 110\u2013112"},{"key":"1076_CR61","unstructured":"NIH\u2014National Heart, Lung, and Blood Institute. Low blood pressure. 2022. https:\/\/www.nhlbi.nih.gov\/health\/health-topics\/topics\/hyp. Accessed 4 Sep 2024"}],"updated-by":[{"DOI":"10.1007\/s10286-025-01170-4","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T00:00:00Z","timestamp":1761523200000}}],"container-title":["Clinical Autonomic Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10286-024-01076-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10286-024-01076-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10286-024-01076-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T08:08:09Z","timestamp":1761638889000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10286-024-01076-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,17]]},"references-count":61,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["1076"],"URL":"https:\/\/doi.org\/10.1007\/s10286-024-01076-7","relation":{},"ISSN":["0959-9851","1619-1560"],"issn-type":[{"value":"0959-9851","type":"print"},{"value":"1619-1560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,17]]},"assertion":[{"value":"12 September 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 October 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 October 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 October 2025","order":5,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":6,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"A Correction to this paper has been published:","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"https:\/\/doi.org\/10.1007\/s10286-025-01170-4","URL":"https:\/\/doi.org\/10.1007\/s10286-025-01170-4","order":8,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The study was approved by the Board for Ethical Questions in Science of the University of Innsbruck, and the study has been performed in accordance with the ethical standards of the 1964 Declaration of Helsinki and its later amendments. All participants gave their writing informed consent prior to their inclusion in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}