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IB is supported by grants R01HL161095 and U01NS122419, and the Overton and Jeannette Smith Foundation. IB is consultant for Theravance Biopharma, Amneal Pharmaceuticals, Regeneron Pharmaceutical, Takeda Pharmaceutical, and Neurawell Therapeutics. Satish R Raj has served as a consultant for Theravance Biopharma, Regeneron, Argenx BV, Antag Therapeutics, and Lumia Health, and receives an honorarium from Elsevier for being Associate Editor of\n                      Autonomic Neurosciences\n                      , and research grants from the Heart and Stroke Foundation of Canada, Dysautonomia International, Standing Up To POTS, and the Canerector Foundation. Horacio Kaufmann is Editor-in-Chief of\n                      Clinical Autonomic Research\n                      , published by Springer Nature, serves as PI of study sponsored by Biogen MA Inc. (TRACK MSA, S19-01846), received consultancy fees from Takeda Pharmaceutical Company Ltd, Ono Pharma UK Ltd, Lundbeck LLC, Theravance Biopharma US Inc., and Vaxxinity, Inc. He received royalties from Up To Date. He receives research support from NIH-NINDS (U01NS122419) and Familial Dysautonomia Foundation. CAS is supported by grants R01HL157584-01, R01HL159203-01. CAS received research support from Alnylam and is consultant for Antag Therapeutics and Theravance Biopharma.","order":1,"name":"Ethics","label":"Conflicts of interest","group":{"name":"EthicsHeading","label":"Declarations"}}]}}