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As such, saccharides can be applied in the food and pharmaceutical industries to stimulate our immune system (e.g., prebiotics), to control diabetes (e.g., low-calorie sweeteners), or as building blocks for anticancer and antiviral drugs (e.g., l-nucleosides). Unfortunately, only a small number of all possible monosaccharides are found in nature in sufficient amounts to allow their commercial exploitation. Consequently, so-called rare sugars have to be produced by (bio)chemical processes starting from cheap and widely available substrates. Three enzyme classes that can be used for rare sugar production are keto\u2013aldol isomerases, epimerases, and oxidoreductases. In this review, the recent developments in rare sugar production with these biocatalysts are discussed.<\/jats:p>","DOI":"10.1007\/s10295-012-1089-x","type":"journal-article","created":{"date-parts":[[2012,2,13]],"date-time":"2012-02-13T14:42:10Z","timestamp":1329144130000},"page":"823-834","source":"Crossref","is-referenced-by-count":192,"title":["Enzymes for the biocatalytic production of rare sugars"],"prefix":"10.1093","volume":"39","author":[{"given":"Koen","family":"Beerens","sequence":"first","affiliation":[{"name":"grid.5342.0 0000000120697798 Centre for Industrial Biotechnology and Biocatalysis, Faculty of Bioscience Engineering Ghent University Coupure links 653 9000 Gent Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom","family":"Desmet","sequence":"additional","affiliation":[{"name":"grid.5342.0 0000000120697798 Centre for Industrial Biotechnology and Biocatalysis, Faculty of Bioscience Engineering Ghent University Coupure links 653 9000 Gent 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