{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T17:28:33Z","timestamp":1790270913551,"version":"4.1.0"},"reference-count":28,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The study was focused on developing a continuous method to produce an alcohol mixture suitable to be used as a gasoline supplement. The immobilized column reactor with wood pulp fibers was successfully used for the continuous production of butanol and isopropanol using Clostridium beijerinckii DSM 6423. A sugar mixture (glucose, mannose, galactose, arabinose and xylose) representing lignocellulose hydrolysate was used as a substrate for the production of solvents. The effect of dilution rate on solvent production was studied during continuous operation. The maximum total solvent concentration of 11.99\u00a0g\/l was obtained at a dilution rate of 0.16\u00a0h\u22121. The maximum solvent productivity (5.58\u00a0g\/l\u00a0h) was obtained at a dilution rate of 1.5\u00a0h\u22121. The maximum solvent yield of 0.45\u00a0g\/g from sugar mixture was observed at 0.25\u00a0h\u22121. The system will be further used for the solvent production using wood hydrolysate as a substrate.<\/jats:p>","DOI":"10.1007\/s10295-012-1219-5","type":"journal-article","created":{"date-parts":[[2012,11,26]],"date-time":"2012-11-26T12:51:36Z","timestamp":1353934296000},"page":"209-215","source":"Crossref","is-referenced-by-count":41,"title":["Wood pulp as an immobilization matrix for the continuous production of isopropanol and butanol"],"prefix":"10.1093","volume":"40","author":[{"given":"Shrikant A","family":"Survase","sequence":"first","affiliation":[{"name":"grid.5373.2 0000000108389418 Department of Biotechnology and Chemical Technology Aalto University School of Chemical Technology POB 16100 00076 Aalto Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriaan","family":"van Heiningen","sequence":"additional","affiliation":[{"name":"grid.21106.34 0000000121820794 Department of Chemical and Biological Engineering University of Maine 5737 Jenness Hall 04469-5737 Orono ME USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom","family":"Granstr\u00f6m","sequence":"additional","affiliation":[{"name":"grid.5373.2 0000000108389418 Department of Biotechnology and Chemical Technology Aalto University School of Chemical Technology POB 16100 00076 Aalto Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2013,2,1]]},"reference":[{"issue":"5","key":"2021033102590776900_CR1","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1007\/BF01040869","article-title":"Acetone-butanol-isopropanol production by Clostridium beijerinckii (Synonym, Clostridium butylicum)","volume":"8","author":"Chen","year":"1986","journal-title":"Biotechnol Letts"},{"key":"2021033102590776900_CR2","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1186\/1754-6834-5-44","article-title":"Introducing a single secondary alcohol dehydrogenase into butanol-tolerant Clostridium acetobutylicum Rh8 switches ABE fermentation to high level IBE fermentation","volume":"5","author":"Dai","year":"2012","journal-title":"Biotechnol Biofuels"},{"issue":"12","key":"2021033102590776900_CR3","doi-asserted-by":"publisher","first-page":"5232","DOI":"10.1016\/j.biortech.2007.09.032","article-title":"Fermentation of dried distillers\u2019 grains and solubles (DDGS) hydrolysates to solvents and value-added products by solventogenic clostridia","volume":"99","author":"Ezeji","year":"2008","journal-title":"Bioresour Technol"},{"issue":"6","key":"2021033102590776900_CR4","doi-asserted-by":"crossref","first-page":"2306","DOI":"10.1128\/AEM.63.6.2306-2310.1997","article-title":"Enhanced butanol production by Clostridium beijerinckii BA101 grown in semi defined P2 medium containing 6 percent maltodextrin or glucose","volume":"63","author":"Formanek","year":"1997","journal-title":"Appl Environ Microbiol"},{"issue":"2","key":"2021033102590776900_CR5","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1128\/AEM.46.2.321-327.1983","article-title":"Acidic conditions are not obligatory for onset of butanol formation by Clostridium beijerinckii (Synonym, C. butylicum)","volume":"46","author":"George","year":"1983","journal-title":"Appl Environ Microbiol"},{"issue":"3","key":"2021033102590776900_CR6","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1128\/AEM.45.3.1160-1163.1983","article-title":"Acetone, isopropanol, and butanol production by Clostridium beijerinckii (syn. 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