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Simple equations were derived to calculate the appropriate concentrations of soy lecithin and agar in aqueous solutions to achieve the desired relaxation times. Phantoms were tested for correspondence between measurements and calculated T1 and T2 values, reproducibility, spatial homogeneity, and temporal stability. T1 and T2 mapping techniques and a 3D T1-weighted sequence with high spatial resolution were applied.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Except for the liver relaxation phantom, all phantoms were successfully and reproducibly produced. Good agreement was found between the targeted and measured relaxation times. The percentage deviations from the targeted relaxation times were less than 3% for T1 and less than 6.5% for T2. In addition, the phantoms were homogeneous and had little to no air bubbles. However, the phantoms were unstable over time: after a storage period of 4\u00a0weeks, mold growth and also changes in relaxation times were detected in almost all phantoms.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Soy-lecithin-agar gels are a non-toxic material for the construction of relaxometry phantoms with tissue-like relaxation times. They are easy to prepare, inexpensive and allow independent adjustment of T1 and T2. However, there is still work to be done to improve the long-term stability of the phantoms.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s10334-024-01166-7","type":"journal-article","created":{"date-parts":[[2024,5,11]],"date-time":"2024-05-11T05:01:57Z","timestamp":1715403717000},"page":"899-907","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["A straightforward procedure to build a non-toxic relaxometry phantom with desired T1 and T2 times at 3T"],"prefix":"10.1007","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0601-9901","authenticated-orcid":false,"given":"Victor","family":"Fritz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabine","family":"Eisele","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petros","family":"Martirosian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00fcrgen","family":"Machann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fritz","family":"Schick","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,5,11]]},"reference":[{"issue":"1","key":"1166_CR1","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1002\/mrm.26982","volume":"79","author":"KE Keenan","year":"2018","unstructured":"Keenan KE, Ainslie M, Barker AJ, Boss MA, Cecil KM, Charles C, Chenevert TL, Clarke L, Evelhoch JL, Finn P, Gembris D, Gunter JL, Hill DLG, Jack CR Jr, Jackson EF, Liu G, Russek SE, Sharma SD, Steckner M, Stupic KF, Trzasko JD, Yuan C, Zheng J (2018) Quantitative magnetic resonance imaging phantoms: A review and the need for a system phantom. 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