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Performance was tested at 1.4\u00a0T, 3\u00a0T, and 11.7\u00a0T using\n                      <jats:sup>1<\/jats:sup>\n                      H MRI,\n                      <jats:sup>13<\/jats:sup>\n                      C spectroscopy, and\n                      <jats:sup>13<\/jats:sup>\n                      C MRSI.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The reference solutions remained chemically and spectrally stable for up to 20\u00a0months under cooled, light-protected storage. Ethyl acetate provided a stable alternative to pyruvate, while gadolinium enabled the control of relaxation properties. Spectral assessment confirmed narrow linewidths, strong SNR, and reproducible peak separation across field strengths, validating the phantom\u2019s suitability for calibration and method development.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>\n                      This low-cost, open-source design provides a durable and reproducible\n                      <jats:sup>13<\/jats:sup>\n                      C phantom that complements existing dynamic and metabolite-specific models. It enables long-term standardization, supports multi-center studies, and facilitates robust quality assurance in hyperpolarized and thermal\n                      <jats:sup>13<\/jats:sup>\n                      C MRSI.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s10334-026-01330-1","type":"journal-article","created":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T08:14:00Z","timestamp":1770884040000},"page":"559-570","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Design and chemical composition of a reference phantom for 13C metabolic MRSI"],"prefix":"10.1007","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-7484-1068","authenticated-orcid":false,"given":"Julian","family":"Sch\u00fcle","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8187-9170","authenticated-orcid":false,"given":"Christoph A.","family":"M\u00fcller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Lucas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonard","family":"Schraff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Menzel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Speidel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilai","family":"Schwartz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8844-3583","authenticated-orcid":false,"given":"Volker","family":"Rasche","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,2,12]]},"reference":[{"issue":"8","key":"1330_CR1","doi-asserted-by":"publisher","first-page":"e71274","DOI":"10.1371\/journal.pone.0071274","volume":"8","author":"CM Walker","year":"2013","unstructured":"Walker CM, Lee J, Ramirez MS, Schellingerhout D, Millward S, Bankson JA (2013) A catalyzing phantom for reproducible dynamic conversion of hyperpolarized [1-13C]-pyruvate. 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