{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T14:05:45Z","timestamp":1785852345786,"version":"3.56.0"},"reference-count":27,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2002,10]]},"DOI":"10.1007\/s10350-004-6420-9","type":"journal-article","created":{"date-parts":[[2004,12,6]],"date-time":"2004-12-06T16:12:47Z","timestamp":1102349567000},"page":"1332-1336","source":"Crossref","is-referenced-by-count":28,"title":["Topical L-Arginine Gel Lowers Resting Anal Pressure"],"prefix":"10.1097","volume":"45","author":[{"given":"N.","family":"Griffin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. D. E.","family":"Zimmerman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. W.","family":"Briel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.-J.","family":"Gruss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Jonas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. G.","family":"Acheson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Neal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. H.","family":"Scholefield","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W. R.","family":"Schouten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"CR1","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1007\/BF02076185","volume":"37","author":"R Farouk","year":"1994","journal-title":"Dis Colon Rectum"},{"key":"CR2","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1002\/bjs.1800730609","volume":"73","author":"CP Gibbons","year":"1986","journal-title":"Br J Surg"},{"key":"CR3","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1002\/bjs.1800640204","volume":"64","author":"BD Hancock","year":"1977","journal-title":"Br J Surg"},{"key":"CR4","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/BF01647999","volume":"2","author":"J Olsen","year":"1987","journal-title":"Int J Colorectal Dis"},{"key":"CR5","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1002\/bjs.1800830120","volume":"83","author":"WR Schouten","year":"1996","journal-title":"Br J Surg"},{"key":"CR6","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1002\/bjs.1800760504","volume":"76","author":"IT Khubchandani","year":"1989","journal-title":"Br J Surg"},{"key":"CR7","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S0140-6736(96)06090-4","volume":"349","author":"JN Lund","year":"1997","journal-title":"Lancet"},{"key":"CR8","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1007\/BF02258394","volume":"40","author":"JN Lund","year":"1997","journal-title":"Dis Colon Rectum"},{"key":"CR9","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1001\/archsurg.1996.01430190097023","volume":"131","author":"HB Hechtman","year":"1996","journal-title":"Arch Surg"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1007\/BF02237218","volume":"43","author":"W Schouten","year":"2000","journal-title":"Dis Colon Rectum"},{"key":"CR11","first-page":"984","volume":"274","author":"YC Luiking","year":"1998","journal-title":"Am J Physiol"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/S0022-5347(01)64297-6","volume":"158","author":"SD Smith","year":"1997","journal-title":"J Urol"},{"key":"CR13","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1007\/BF02236692","volume":"42","author":"G Dorfman","year":"1999","journal-title":"Dis Colon Rectum"},{"key":"CR14","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1038\/sj.bjp.0703322","volume":"130","author":"MK Mundey","year":"2000","journal-title":"Br J Pharmacol"},{"key":"CR15","first-page":"7","volume":"264","author":"S Chakder","year":"1993","journal-title":"Am J Physiol"},{"key":"CR16","first-page":"107","volume":"262","author":"S Rattan","year":"1992","journal-title":"Am J Physiol"},{"key":"CR17","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/0016-5085(92)90084-C","volume":"102","author":"A Tottrup","year":"1992","journal-title":"Gastroenterology"},{"key":"CR18","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1136\/gut.34.5.689","volume":"34","author":"T O?Kelly","year":"1993","journal-title":"Gut"},{"key":"CR19","first-page":"31","volume":"78","author":"TJ O?Kelly","year":"1996","journal-title":"Ann R Coll Surg Engl"},{"key":"CR20","first-page":"1075","volume":"272","author":"EB Glavind","year":"1997","journal-title":"Am J Physiol"},{"key":"CR21","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.3109\/00365529609036909","volume":"31","author":"S Buntzen","year":"1996","journal-title":"Scand J Gastroenterol"},{"key":"CR22","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1002\/bjs.1800830417","volume":"83","author":"JF Stebbing","year":"1996","journal-title":"Br J Surg"},{"key":"CR23","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1007\/BF02053596","volume":"37","author":"TJ O?Kelly","year":"1994","journal-title":"Dis Colon Rectum"},{"key":"CR24","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1038\/347768a0","volume":"347","author":"DS Bredt","year":"1990","journal-title":"Nature"},{"key":"CR25","first-page":"277","volume":"263","author":"S Ward","year":"1992","journal-title":"Am J Physio"},{"key":"CR26","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/0016-5085(92)91093-J","volume":"103","author":"S Rattan","year":"1992","journal-title":"Gastroenterology"},{"key":"CR27","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/0016-5085(93)90901-N","volume":"105","author":"S Rattan","year":"1993","journal-title":"Gastroenterology"}],"container-title":["Diseases of the Colon & Rectum"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00003453-200245100-00008","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T13:41:36Z","timestamp":1785850896000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00003453-200245100-00008"}},"subtitle":["Possible Treatment for Anal Fissure"],"short-title":[],"issued":{"date-parts":[[2002,10]]},"references-count":27,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2002]]}},"URL":"https:\/\/doi.org\/10.1007\/s10350-004-6420-9","relation":{},"ISSN":["0012-3706"],"issn-type":[{"value":"0012-3706","type":"print"}],"subject":[],"published":{"date-parts":[[2002,10]]}}}