{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:07:13Z","timestamp":1786118833881,"version":"build-2736575974"},"reference-count":32,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,1]]},"DOI":"10.1007\/s10350-007-9099-x","type":"journal-article","created":{"date-parts":[[2007,11,20]],"date-time":"2007-11-20T16:26:33Z","timestamp":1195575993000},"page":"32-37","source":"Crossref","is-referenced-by-count":40,"title":["Impact of Pelvic Radiotherapy on Morbidity and Durability of Sphincter Preservation After Coloanal Anastomosis for Rectal Cancers"],"prefix":"10.1097","volume":"51","author":[{"given":"Imran","family":"Hassan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David W.","family":"Larson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce G.","family":"Wolff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert R.","family":"Cima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heidi K.","family":"Chua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dieter","family":"Hahnloser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan M.","family":"O'Byrne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dirk R.","family":"Larson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John H.","family":"Pemberton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"9099_CR1","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1016\/S0039-6109(02)00048-8","volume":"82","author":"DM Ota","year":"2002","unstructured":"Ota DM, Jacobs L, Kuvshinoff B. Rectal cancer: the sphincter-sparing approach. Surg Clin North Am 2002;82:983\u201393.","journal-title":"Surg Clin North Am"},{"key":"9099_CR2","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.soc.2004.11.008","volume":"14","author":"VW Fazio","year":"2005","unstructured":"Fazio VW, Heriot AG. Proctectomy with coloanal anastomosis. Surg Oncol Clin North Am 2005;14:157\u201381.","journal-title":"Surg Oncol Clin North Am"},{"key":"9099_CR3","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1002\/bjs.4296","volume":"90","author":"MG Tytherleigh","year":"2003","unstructured":"Tytherleigh MG, Mortensen NJ. Options for sphincter preservation in surgery for low rectal cancer. Br J Surg 2003;90:922\u201333.","journal-title":"Br J Surg"},{"key":"9099_CR4","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1007\/s002689900297","volume":"21","author":"JG Guillem","year":"1997","unstructured":"Guillem JG. Ultra-low anterior resection and coloanal pouch reconstruction for carcinoma of the distal rectum. World J Surg 1997;21:721\u20137.","journal-title":"World J Surg"},{"key":"9099_CR5","doi-asserted-by":"crossref","unstructured":"Adjuvant radiotherapy for rectal cancer: a systematic overview of 8,507 patients from 22 randomised trials. Lancet 2001;358:1291\u2013304.","DOI":"10.1016\/S0140-6736(01)06409-1"},{"key":"9099_CR6","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1001\/jama.284.8.1008","volume":"284","author":"C Camma","year":"2000","unstructured":"Camma C, Giunta M, Fiorica F, et al. Preoperative radiotherapy for resectable rectal cancer: a meta-analysis. JAMA 2000;284:1008\u201315.","journal-title":"JAMA"},{"key":"9099_CR7","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/0002-9610(94)90058-2","volume":"167","author":"PB Paty","year":"1994","unstructured":"Paty PB, Enker WE, Cohen AM, et al. Long-term functional results of coloanal anastomosis for rectal cancer. Am J Surg 1994;167:90\u20135.","journal-title":"Am J Surg"},{"key":"9099_CR8","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/S1053-4296(98)80034-9","volume":"8","author":"BD Minsky","year":"1998","unstructured":"Minsky BD. Sphincter preservation in rectal cancer. Preoperative radiation therapy followed by low anterior resection with coloanal anastomosis. Semin Radiat Oncol 1998;8:30\u20135.","journal-title":"Semin Radiat Oncol"},{"key":"9099_CR9","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1054\/bjoc.1999.1052","volume":"82","author":"AS Allal","year":"2000","unstructured":"Allal AS, Bieri S, Pelloni A, et al. Sphincter-sparing surgery after preoperative radiotherapy for low rectal cancers: feasibility, oncologic results and quality of life outcomes. Br J Cancer 2000;82:1131\u20137.","journal-title":"Br J Cancer"},{"key":"9099_CR10","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1007\/s003840100306","volume":"16","author":"NK Kim","year":"2001","unstructured":"Kim NK, Lim DJ, Yun SH, et al. Ultralow anterior resection and coloanal anastomosis for distal rectal cancer: functional and oncological results. Int J Colorectal Dis 2001;16:234\u20137.","journal-title":"Int J Colorectal Dis"},{"key":"9099_CR11","doi-asserted-by":"crossref","first-page":"1578","DOI":"10.1007\/s10350-004-0654-4","volume":"47","author":"J Hida","year":"2004","unstructured":"Hida J, Yoshifuji T, Tokoro T, et al. Comparison of long-term functional results of colonic J-pouch and straight anastomosis after low anterior resection for rectal cancer: a five-year follow-up. Dis Colon Rectum 2004;47:1578\u201385.","journal-title":"Dis Colon Rectum"},{"key":"9099_CR12","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1007\/s10350-004-6679-x","volume":"46","author":"DR Nathanson","year":"2003","unstructured":"Nathanson DR, Espat NJ, Nash GM, et al. Evaluation of preoperative and postoperative radiotherapy on long-term functional results of straight coloanal anastomosis. Dis Colon Rectum 2003;46:888\u201394.","journal-title":"Dis Colon Rectum"},{"key":"9099_CR13","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0360-3016(98)00180-1","volume":"42","author":"R Wagman","year":"1998","unstructured":"Wagman R, Minsky BD, Cohen AM, et al. Sphincter preservation in rectal cancer with preoperative radiation therapy and coloanal anastomosis: long term follow-up. Int J Radiat Oncol Biol Phys 1998;42:51\u20137.","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"9099_CR14","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1097\/00000658-200111000-00008","volume":"234","author":"E Rullier","year":"2001","unstructured":"Rullier E, Goffre B, Bonnel C, et al. Preoperative radiochemotherapy and sphincter-saving resection for T3 carcinomas of the lower third of the rectum. Ann Surg 2001;234:633\u201340.","journal-title":"Ann Surg"},{"key":"9099_CR15","doi-asserted-by":"crossref","first-page":"1778","DOI":"10.1007\/BF02234455","volume":"44","author":"TE Read","year":"2001","unstructured":"Read TE, Ogunbiyi OA, Fleshman JW, et al. Neoadjuvant external beam radiation and proctectomy for adenocarcinoma of the rectum. Dis Colon Rectum 2001;44:1778\u201390.","journal-title":"Dis Colon Rectum"},{"key":"9099_CR16","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.1007\/s10350-004-7251-4","volume":"45","author":"N Dehni","year":"2002","unstructured":"Dehni N, McNamara DA, Schlegel RD, et al. Clinical effects of preoperative radiation therapy on anorectal function after proctectomy and colonic J-pouch-anal anastomosis. Dis Colon Rectum 2002;45:1635\u201340.","journal-title":"Dis Colon Rectum"},{"key":"9099_CR17","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1007\/BF02235256","volume":"41","author":"M Dahlberg","year":"1998","unstructured":"Dahlberg M, Glimelius B, Graf W, Pahlman L. Preoperative irradiation affects functional results after surgery for rectal cancer: results from a randomized study. Dis Colon Rectum 1998;41:543\u201351.","journal-title":"Dis Colon Rectum"},{"key":"9099_CR18","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1007\/BF00298533","volume":"10","author":"WG Lewis","year":"1995","unstructured":"Lewis WG, Williamson ME, Kuzu A, et al. Potential disadvantages of post-operative adjuvant radiotherapy after anterior resection for rectal cancer: a pilot study of sphincter function, rectal capacity and clinical outcome. Int J Colorectal Dis 1995;10:133\u20137.","journal-title":"Int J Colorectal Dis"},{"key":"9099_CR19","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1097\/00000658-199411000-00012","volume":"220","author":"CF Kollmorgen","year":"1994","unstructured":"Kollmorgen CF, Meagher AP, Wolff BG, et al. The long-term effect of adjuvant postoperative chemoradiotherapy for rectal carcinoma on bowel function. Ann Surg 1994;220:676\u201382.","journal-title":"Ann Surg"},{"key":"9099_CR20","doi-asserted-by":"crossref","first-page":"1667","DOI":"10.1007\/BF02234388","volume":"44","author":"P Gervaz","year":"2001","unstructured":"Gervaz P, Rotholtz N, Wexner SD, et al. Colonic J-pouch function in rectal cancer patients: impact of adjuvant chemoradiotherapy. Dis Colon Rectum 2001;44:1667\u201375.","journal-title":"Dis Colon Rectum"},{"key":"9099_CR21","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S1091-255X(01)80027-5","volume":"5","author":"A Fichera","year":"2001","unstructured":"Fichera A, Michelassi F. Long-term prospective assessment of functional results after proctectomy with coloanal anastomosis. J Gastrointest Surg 2001;5:153\u20137.","journal-title":"J Gastrointest Surg"},{"key":"9099_CR22","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1097\/00000658-199806000-00003","volume":"227","author":"S Zaheer","year":"1998","unstructured":"Zaheer S, Pemberton JH, Farouk R, et al. Surgical treatment of adenocarcinoma of the rectum. Ann Surg 1998;227:800\u201311.","journal-title":"Ann Surg"},{"key":"9099_CR23","first-page":"115","volume-title":"Nonparametric statistical methods","author":"M Hollander","year":"1973","unstructured":"Hollander M, Wolfe DA. Nonparametric statistical methods. New York: John Wiley and Sons, 1973:115\u201320."},{"key":"9099_CR24","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1080\/01621459.1952.10483441","volume":"47","author":"WH Kruskal","year":"1952","unstructured":"Kruskal WH, Wallis WA. Use of ranks in one-criterion variance analysis. J Am Stat Assoc 1952;47:583\u2013621.","journal-title":"J Am Stat Assoc"},{"key":"9099_CR25","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1080\/01621459.1958.10501452","volume":"53","author":"EL Kaplan","year":"1958","unstructured":"Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc 1958;53:457\u201381.","journal-title":"J Am Stat Assoc"},{"key":"9099_CR26","doi-asserted-by":"crossref","first-page":"185","DOI":"10.2307\/2344317","volume":"135","author":"R Peto","year":"1972","unstructured":"Peto R, Peto J. Asymptotically efficient rank invariant procedures. J Royal Stat Soc 1972;135:185\u2013207.","journal-title":"J Royal Stat Soc"},{"key":"9099_CR27","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1002\/bjs.5188","volume":"93","author":"AG Heriot","year":"2006","unstructured":"Heriot AG, Tekkis PP, Constantinides V, et al. Meta-analysis of colonic reservoirs versus straight coloanal anastomosis after anterior resection. Br J Surg 2006;93:19\u201332.","journal-title":"Br J Surg"},{"key":"9099_CR28","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1097\/00000658-200207000-00009","volume":"236","author":"YH Ho","year":"2002","unstructured":"Ho YH, Brown S, Heah SM, et al. Comparison of J-pouch and coloplasty pouch for low rectal cancers: a randomized, controlled trial investigating functional results and comparative anastomotic leak rates. Ann Surg 2002;236:49\u201355.","journal-title":"Ann Surg"},{"key":"9099_CR29","first-page":"214","volume":"238","author":"M Machado","year":"2003","unstructured":"Machado M, Nygren J, Goldman S, Ljungqvist O. Similar outcome after colonic pouch and side-to-end anastomosis in low anterior resection for rectal cancer: a prospective randomized trial. Ann Surg 2003;238:214\u201320.","journal-title":"Ann Surg"},{"key":"9099_CR30","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1007\/BF02235358","volume":"41","author":"N Dehni","year":"1998","unstructured":"Dehni N, Tiret E, Singland JD, et al. Long-term functional outcome after low anterior resection: comparison of low colorectal anastomosis and colonic J-pouch-anal anastomosis. Dis Colon Rectum 1998;41:817\u201323.","journal-title":"Dis Colon Rectum"},{"key":"9099_CR31","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1097\/00000658-199607000-00009","volume":"224","author":"O Hallbook","year":"1996","unstructured":"Hallbook O, Pahlman L, Krog M, et al. Randomized comparison of straight and colonic J pouch anastomosis after low anterior resection. Ann Surg 1996;224:58\u201365.","journal-title":"Ann Surg"},{"key":"9099_CR32","doi-asserted-by":"crossref","first-page":"6199","DOI":"10.1200\/JCO.2005.14.779","volume":"23","author":"KC Peeters","year":"2005","unstructured":"Peeters KC, van de Velde CJ, Leer JW, et al. Late side effects of short-course preoperative radiotherapy combined with total mesorectal excision for rectal cancer: increased bowel dysfunction in irradiated patients\u2014a Dutch colorectal cancer group study. J Clin Oncol 2005;23:6199\u2013206.","journal-title":"J Clin Oncol"}],"container-title":["Diseases of the Colon &amp; Rectum"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00003453-200851010-00006","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T16:54:08Z","timestamp":1786035248000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00003453-200851010-00006"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,1]]},"references-count":32,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008]]}},"URL":"https:\/\/doi.org\/10.1007\/s10350-007-9099-x","relation":{},"ISSN":["0012-3706"],"issn-type":[{"value":"0012-3706","type":"print"}],"subject":[],"published":{"date-parts":[[2008,1]]}}}