{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T15:13:24Z","timestamp":1791645204324,"version":"4.3.4"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"3-4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Wien Med Wochenschr"],"published-print":{"date-parts":[[2013,2]]},"DOI":"10.1007\/s10354-012-0169-x","type":"journal-article","created":{"date-parts":[[2012,12,19]],"date-time":"2012-12-19T08:17:50Z","timestamp":1355905070000},"page":"65-72","source":"Crossref","is-referenced-by-count":95,"title":["STW 5 (Iberogast\u00ae)\u2014a safe and effective standard in the treatment of functional gastrointestinal disorders","STW 5 (Iberogast\u00ae) \u2013 Ein wirksamer und vertr\u00e4glicher Standard in der Therapie funktioneller Magen-Darm-Erkrankungen"],"prefix":"10.1007","volume":"163","author":[{"given":"Bertram","family":"Ottillinger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Storr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Malfertheiner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans-Dieter","family":"Allescher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2012,12,20]]},"reference":[{"key":"169_CR1","first-page":"1","volume":"37","author":"Arzneimittelkommission der deutschen \u00c4rzteschaft","year":"2010","unstructured":"Arzneimittelkommission der deutschen \u00c4rzteschaft. Empfehlungen zur Therapie bei Funktioneller Dyspepsie und Reizdarmsyndrom. 2. Aufl. Arzneiverordn Prax. 2010;37:1\u201329.","journal-title":"Arzneiverordn Prax"},{"key":"169_CR2","first-page":"6","volume":"1","author":"V Eckardt","year":"2009","unstructured":"Eckardt V. Funktionelle Magen-Darm-Erkrankungen. Selecta. 2009;1:6\u201311.","journal-title":"Selecta"},{"issue":"5","key":"169_CR3","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1053\/j.gastro.2006.03.008","volume":"130","author":"DA Drossmann","year":"2006","unstructured":"Drossmann DA. The functional gastrointestinal disorders and the Rome III process. Gastroenterology. 2006;130(5):1377\u201390.","journal-title":"Gastroenterology"},{"key":"169_CR4","doi-asserted-by":"crossref","first-page":"1552","DOI":"10.1053\/j.gastro.2006.03.011","volume":"130","author":"WG Thompson","year":"2006","unstructured":"Thompson WG. The road to Rome. Gastroenterology. 2006;130:1552\u20136.","journal-title":"Gastroenterology"},{"issue":"5","key":"169_CR5","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.1053\/j.gastro.2005.11.059","volume":"130","author":"J Tack","year":"2006","unstructured":"Tack J, Talley NJ, Camilleri M, et al. Functional gastroduodenal disorders. Gastroenterology. 2006;130(5):1466\u201379.","journal-title":"Gastroenterology"},{"issue":"5","key":"169_CR6","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1053\/j.gastro.2005.11.061","volume":"130","author":"GF Longstreth","year":"2006","unstructured":"Longstreth GF, Thompson WG, Chey WD, et al. Functional bowel disorders. Gastroenterology. 2006;130(5):1480\u201391.","journal-title":"Gastroenterology"},{"key":"169_CR7","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1055\/s-0029-1245976","volume":"49","author":"P Layer","year":"2011","unstructured":"Layer P, Andresen V, Pehl C, et al. S3-Leitlinie Reizdarmsyndrom: Definition, Pathophysiologie, Diagnostik und Therapie. Gemeinsame Leitlinie der Deutschen Gesellschaft f\u00fcr Verdauungs- und Stoffwechselkrankheiten (DGVS) und der Deutschen Gesellschaft f\u00fcr Neurogastroenterologie und Motilit\u00e4t (DGNM). AWMF-Registriernummer: 021\/016,2011. Z Gastroenterol. 2011;49:237\u201393.","journal-title":"Z Gastroenterol"},{"key":"169_CR8","first-page":"169","volume":"6","author":"A Teubner","year":"2007","unstructured":"Teubner A, J\u00fcrgensen C, St\u00f6lzel U. Funktionelle Dyspepsie und Reizdarmsyndrom. Arzt Krankenh. 2007;6:169\u201374.","journal-title":"Arzt Krankenh"},{"issue":"Suppl 7","key":"169_CR9","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1111\/j.1365-2036.2004.02183.x","volume":"20","author":"L Chang","year":"2004","unstructured":"Chang L. Review article: epidemiology and quality of life in functional gastrointestinal disorders. Aliment Pharmacol Ther. 2004;20(Suppl 7):31\u20139.","journal-title":"Aliment Pharmacol Ther"},{"key":"169_CR10","first-page":"167","volume-title":"Botanical medicine: from bench to bedside","author":"B Vinson","year":"2009","unstructured":"Vinson B. Development of Iberogast: clinical evidence for multicomponent herbal mixtures. In: Cooper R, Kronenberg F, editors. Botanical medicine: from bench to bedside. New Rochelle: Mary Ann Liebert; 2009. pp. 167\u201389."},{"key":"169_CR11","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1111\/j.1572-0241.2006.01183.x","volume":"102","author":"U Arnim von","year":"2007","unstructured":"von Arnim U, Peitz U, Vinson B, et al. STW 5, a phytopharmacon for patients with functional dyspepsia: results of a multicenter, placebo-controlled double-blind study. Am J Gastroenterol. 2007;102:1268\u201375.","journal-title":"Am J Gastroenterol"},{"issue":"1","key":"169_CR12","first-page":"45","volume":"15","author":"D Buchert","year":"1994","unstructured":"Buchert D. Wirksamkeit und Vertr\u00e4glichkeit von Iberogast bei Patienten mit gesicherter Non Ulcus Dyspepsie. Z Phytotherapie. 1994;15(1):45\u20136.","journal-title":"Z Phytotherapie"},{"key":"169_CR13","first-page":"1","volume":"39","author":"A Madisch","year":"2001","unstructured":"Madisch A, Melderis H, Mayr G, et al. Ein Phytotherapeutikum und seine modifizierte Rezeptur bei funktioneller Dyspepsie. Z Gastroenterologie. 2001;39:1\u20138.","journal-title":"Z Gastroenterologie"},{"issue":"6","key":"169_CR14","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1111\/j.1365-2982.2008.01249.x","volume":"21","author":"B Braden","year":"2009","unstructured":"Braden B, Caspary W, B\u00f6rner N, et al. Clinical effects of STW 5 (Iberogast) are not based on acceleration of gastric emptying in patients with functional dyspepsia and gastroparesis. Neurogastroenterol Motil. 2009;21(6):632\u20138, e25.","journal-title":"Neurogastroenterol Motil"},{"issue":"6","key":"169_CR15","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1055\/s-2002-32130","volume":"40","author":"W R\u00f6sch","year":"2002","unstructured":"R\u00f6sch W, Vinson B, Sassin I. A randomised clinical trial comparing the efficacy of a herbal preparation STW 5 with the prokinetic drug cisapride in patients with dysmotility type of functional dyspepsia. Z Gastroenterol. 2002;40(6):401\u20138.","journal-title":"Z Gastroenterol"},{"issue":"3","key":"169_CR16","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1111\/j.1365-2036.2004.01859.x","volume":"19","author":"A Madisch","year":"2004","unstructured":"Madisch A, Holtmann G, Plein K, et al. Treatment of irritable bowel syndrome with herbal preparations: results of a double-blind, randomized, placebo-controlled, multi-centre trial. Aliment Pharmacol Ther. 2004;19(3):271\u20139.","journal-title":"Aliment Pharmacol Ther"},{"issue":"1","key":"169_CR17","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/BF02850118","volume":"20","author":"K Gundermann","year":"2003","unstructured":"Gundermann K, Godehardt E, Ulbrich M. Efficacy of a herbal preparation in patients with functional dyspepsia: a meta-analysis of double-blind, randomized, clinical trials. Adv Ther. 2003;20(1):43\u20139.","journal-title":"Adv Ther"},{"issue":"11\u201312","key":"169_CR18","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1111\/j.1365-2036.2004.02275.x","volume":"20","author":"J Melzer","year":"2004","unstructured":"Melzer J, R\u00f6sch W, Reichling J, et al. Meta-analysis: phytotherapy of functional dyspepsia with the herbal drug preparation STW 5 (Iberogast). Aliment Pharmacol Ther. 2004;20(11\u201312):1279\u201387.","journal-title":"Aliment Pharmacol Ther"},{"key":"169_CR19","unstructured":"Holtmann G, Nandurkar S, Talley NJ, et al. Herbal medicine for the treatment of functional dyspepsia: a systematic review of the literature and meta-analysis. Gastroenterology. 2007;132(4) Supp 2 (Abstract W1204)."},{"issue":"Suppl. II","key":"169_CR20","first-page":"91","volume":"7","author":"I Sassin","year":"2000","unstructured":"Sassin I, Buchert D. Efficacy and tolerability of the herbal preparation Iberogast\u00ae in the therapy of functional dyspepsia. Phytomedicine. 2000;7(Suppl. II):91\u20132 (69P).","journal-title":"Phytomedicine."},{"key":"169_CR21","unstructured":"Klein-Galczinsky C, Sassin I. Anwendungsbeobachtung zur Wirksamkeit und Vertr\u00e4glichkeit von Iberogast\u00ae in der Therapie des Colon irritabile. Phytotherapie an der Schwelle zum neuen Jahrtausend 1999;125 (Abstract P25)."},{"issue":"10","key":"169_CR22","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1055\/s-2007-963357","volume":"45","author":"R Raedsch","year":"2007","unstructured":"Raedsch R, Hanisch J, Bock P, et al. Wirksamkeit und Unbedenklichkeit des Phytopharmakons STW 5 versus Metoclopramid oral bei funktioneller Dyspepsie unter Praxisbedinungen. Z Gastroenterol. 2007;45(10):1041\u20138.","journal-title":"Z Gastroenterol"},{"key":"169_CR23","first-page":"1","volume":"10","author":"KJ Gundermann","year":"2004","unstructured":"Gundermann KJ, Vinson B, H\u00e4nicke S. Die funktionelle Dyspepsie bei Kindern \u2013 eine retrospektive Studie mit einem Phytopharmakon. P\u00e4d. 2004;10:1\u20136.","journal-title":"P\u00e4d"},{"key":"169_CR24","volume-title":"Experience reports of the application of Iberogast in children. Research report","author":"K Leichtle","year":"1999","unstructured":"Leichtle K. Experience reports of the application of Iberogast in children. Research report. Steigerwald: Arzneimittelwerk; 1999."},{"key":"169_CR25","doi-asserted-by":"crossref","unstructured":"Vinson BR, Radke M. The herbal preparation STW 5 for the treatment of functional gastrointestinal diseases in children aged 3\u201314 years\u2014a prospective non interventional study. Digestive disease week, Chicago, IL, USA. 8 May 2011 (Abstract #523).","DOI":"10.1016\/S0016-5085(11)60415-0"},{"issue":"4","key":"169_CR26","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1111\/j.1365-2036.2005.02572.x","volume":"22","author":"B Adam","year":"2005","unstructured":"Adam B, Liebregts T, Saadat-Gilani K, et al. Validation of the gastrointestinal symptom score for the assessment of symptoms in patients with functional dyspepsia. Aliment Pharmacol Ther. 2005;22(4):357\u201363.","journal-title":"Aliment Pharmacol Ther"},{"key":"169_CR27","doi-asserted-by":"crossref","unstructured":"von Arnim U, Vinson BR, Malfertheiner P, et al. Functional dyspepsia: are relapse rates influenced by active treatment. Gastroenterology. 2008;134 (Abstract W1085).","DOI":"10.1016\/S0016-5085(08)62942-X"},{"key":"169_CR28","unstructured":"Summary of product characteristics (SmPC, Fachinformation) Iberogast\u00ae. STEIGERWALD Arzneimittelwerk GmbH. Oktober 2010."},{"key":"169_CR29","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1055\/s-0031-1298578","volume":"78","author":"W Kn\u00f6ss","year":"2012","unstructured":"Kn\u00f6ss W, Chinou I. Regulation of medicinal plants for public health\u2014European community monographs on herbal substances. Planta Med. 2012;78:1311\u20136.","journal-title":"Planta Med"},{"issue":"Suppl. 5","key":"169_CR30","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.phymed.2006.03.021","volume":"13","author":"H Wagner","year":"2006","unstructured":"Wagner H. Multitarget therapy: the future of treatment for more than just functional dyspepsia. Phytomedicine. 2006;13(Suppl. 5):122\u201399.","journal-title":"Phytomedicine"},{"issue":"Suppl. 5","key":"169_CR31","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.phymed.2006.07.001","volume":"13","author":"T Wegener","year":"2006","unstructured":"Wegener T, Wagner H. The active components and the pharmacological multi-target principle of STW 5 (Iberogast). Phytomedicine. 2006;13(Suppl. 5):20\u201335.","journal-title":"Phytomedicine"},{"key":"169_CR32","unstructured":"Bundesinstitut f\u00fcr Arzneimittel und Medizinprodukte. Abwehr von Gefahren durch Arzneimittel, Stufe II. Metoclopramid-haltige Arzneimittel: Wirksamkeits- und Sicherheitsbedenken (hinsichtlich neurologischer und kardiovaskul\u00e4rer Ereignisse). Bonn 2. Jan. 2012."},{"issue":"35\/36","key":"169_CR33","first-page":"A1779","volume":"109","author":"Arzneimittelkommission der deutschen \u00c4rzteschaft","year":"2012","unstructured":"Arzneimittelkommission der deutschen \u00c4rzteschaft. UAW-News International. Ventrikul\u00e4re Arrhythmien und pl\u00f6tzlicher Herztod im Zusammenhang mit Domperidon. Deutsches \u00c4rzteblatt. 2012;109(35\/36):A1779\u201380.","journal-title":"Deutsches \u00c4rzteblatt"},{"issue":"4","key":"169_CR34","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1177\/1756283X12437358","volume":"5","author":"JJ Heidelbaugh","year":"2012","unstructured":"Heidelbaugh JJ, Kim AH, Chang R, et al. Overutilization of proton-pump inhibitors: what the clinician needs to know. Therap Adv Gastroenterol. 2012;5(4):219\u201332.","journal-title":"Therap Adv Gastroenterol"},{"issue":"11","key":"169_CR35","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1055\/s-2001-18536","volume":"39","author":"P Malfertheiner","year":"2001","unstructured":"Malfertheiner P, Holtmann G, Peitz U, et al. Guidelines of the German society of metabolic and digestive diseases for the therapy of dyspepsia. Z Gastroenterol. 2001;39(11):937\u201356.","journal-title":"Z Gastroenterol"}],"container-title":["Wiener Medizinische Wochenschrift"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10354-012-0169-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,7]],"date-time":"2019-07-07T07:00:11Z","timestamp":1562482811000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10354-012-0169-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,12,20]]},"references-count":35,"journal-issue":{"issue":"3-4","published-print":{"date-parts":[[2013,2]]}},"alternative-id":["169"],"URL":"https:\/\/doi.org\/10.1007\/s10354-012-0169-x","relation":{},"ISSN":["0043-5341","1563-258X"],"issn-type":[{"value":"0043-5341","type":"print"},{"value":"1563-258X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,12,20]]}}}