{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:27:16Z","timestamp":1740126436526,"version":"3.37.3"},"reference-count":11,"publisher":"Springer Science and Business Media LLC","issue":"11-12","license":[{"start":{"date-parts":[[2022,5,20]],"date-time":"2022-05-20T00:00:00Z","timestamp":1653004800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,5,20]],"date-time":"2022-05-20T00:00:00Z","timestamp":1653004800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100005788","name":"Medical University of Vienna","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100005788","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Wien Med Wochenschr"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Immediate-type hypersensitivity reactions (IHRs) to carboplatin (CA) are most commonly reported in ovarian cancer patients. A\u00a054-year-old woman with stage\u00a0IV melanoma suffering from metastasis in the entire right lower extremity was presented to our allergy outpatient clinic for diagnostic work-up due to an anaphylactic reaction with palmoplantar erythema, conjunctivitis along with facial erythema, and an incipient decrease in blood pressure during a\u00a0chemotherapy regimen with dacarbazine and carboplatin upon re-administration. A\u00a0subsequently carried out allergological work-up with skin testing (ST) revealed CA to be the culprit drug, whereas cisplatin (CI) was confirmed to be a\u00a0safe alternative for the patient for following treatments. Here, we report a\u00a0case of an IHR to carboplatin in a\u00a0melanoma patient, with CI serving as a\u00a0safe alternative diagnosed by skin testing.<\/jats:p>","DOI":"10.1007\/s10354-022-00938-x","type":"journal-article","created":{"date-parts":[[2022,5,20]],"date-time":"2022-05-20T17:25:04Z","timestamp":1653067504000},"page":"256-259","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Anaphylactic reaction to carboplatin diagnosed by skin testing\u2014a\u00a0reliable tool in platinum-based immediate-type hypersensitivity reactions","Diagnose einer anaphylaktischen Reaktion auf Carboplatin durch allergologische Hauttestungen\u00a0\u2013 eine zuverl\u00e4ssige Methode bei platinbasierten allergischen Reaktionen"],"prefix":"10.1007","volume":"173","author":[{"given":"Elias","family":"Marquart","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmad","family":"Jalili","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadine","family":"Mothes-Luksch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephan N.","family":"Wagner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8238-2561","authenticated-orcid":false,"given":"Tamar","family":"Kinaciyan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,5,20]]},"reference":[{"issue":"8","key":"938_CR1","doi-asserted-by":"publisher","first-page":"827","DOI":"10.1093\/oxfordjournals.annonc.a010762","volume":"7","author":"SS Legha","year":"1996","unstructured":"Legha\u00a0SS, et al. Treatment of metastatic melanoma with combined chemotherapy containing cisplatin, vinblastine and dacarbazine (CVD) and biotherapy using interleukin\u20112 and interferon-alpha. Ann Oncol. 1996;7(8):827\u201335.","journal-title":"Ann Oncol"},{"key":"938_CR2","doi-asserted-by":"publisher","unstructured":"Makrilia N, Syrigou E, Kaklamanos I, et\u00a0al. Hypersensitivity reactions associated with platinum antineoplastic agents: a\u00a0systematic review. Met Based Drugs. 2010:207084. https:\/\/doi.org\/10.1155\/2010\/207084.","DOI":"10.1155\/2010\/207084"},{"key":"938_CR3","doi-asserted-by":"publisher","first-page":"800","DOI":"10.3389\/fphar.2017.00800","volume":"8","author":"YH Tai","year":"2017","unstructured":"Tai\u00a0YH, Tai\u00a0YJ, Hsu\u00a0HC, et\u00a0al. Risk factors of hypersensitivity to carboplatin in patients with gynecologic malignancies. Front Pharmacol. 2017;8:800.","journal-title":"Front Pharmacol"},{"issue":"6","key":"938_CR4","doi-asserted-by":"publisher","first-page":"702","DOI":"10.1111\/all.12142","volume":"68","author":"K Brockow","year":"2013","unstructured":"Brockow\u00a0K, Garvey\u00a0LH, Aberer\u00a0W, et\u00a0al. Skin test concentrations for systemically administered drugs\u2014an ENDA\/EAACI Drug Allergy Interest Group position paper. Allergy. 2013;68(6):702\u201312.","journal-title":"Allergy"},{"issue":"3","key":"938_CR5","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1097\/CAD.0b013e32833418c0","volume":"21","author":"E Syrigou","year":"2010","unstructured":"Syrigou\u00a0E, Makrilia\u00a0N, Vassias\u00a0A, et\u00a0al. Administration of cisplatin in three patients with carboplatin hypersensitivity: is skin testing useful? Anticancer Drugs. 2010;21(3):333\u20138.","journal-title":"Anticancer Drugs"},{"key":"938_CR6","doi-asserted-by":"publisher","unstructured":"Cernadas J, Vasconcelos MJ, Fernandes AP, et al. Desensitization to carboplatin in low-grade glioma. A revision of 100 treatments in children. Pediatr Allergy Immunol. 2021. https:\/\/doi.org\/10.22541\/au.160636142.23443328\/v1.","DOI":"10.22541\/au.160636142.23443328\/v1"},{"issue":"3","key":"938_CR7","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1016\/S0090-8258(03)00178-1","volume":"89","author":"PG Rose","year":"2003","unstructured":"Rose\u00a0PG, Fusco\u00a0N, Smrekar\u00a0M, et\u00a0al. Successful administration of carboplatin in patients with clinically documented carboplatin hypersensitivity. Gynecol Oncol. 2003;89(3):429\u201333.","journal-title":"Gynecol Oncol"},{"issue":"7","key":"938_CR8","doi-asserted-by":"publisher","first-page":"844","DOI":"10.1111\/all.12161","volume":"68","author":"K Scherer","year":"2013","unstructured":"Scherer\u00a0K, Brockow\u00a0K, Aberer\u00a0W, et\u00a0al. Desensitization in delayed drug hypersensitivity reactions\u2014an EAACI position paper of the Drug Allergy Interest Group. Allergy. 2013;68(7):844\u201352.","journal-title":"Allergy"},{"issue":"6","key":"938_CR9","doi-asserted-by":"publisher","first-page":"856","DOI":"10.1016\/j.jaip.2015.07.003","volume":"3","author":"T Lax","year":"2015","unstructured":"Lax\u00a0T, Long\u00a0A, Banerji\u00a0A. Skin testing in the evaluation and management of carboplatin-related hypersensitivity reactions. J\u00a0Allergy Clin Immunol Pract. 2015;3(6):856\u201362.","journal-title":"J Allergy Clin Immunol Pract"},{"issue":"1","key":"938_CR10","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1016\/j.ygyno.2016.10.023","volume":"144","author":"A Bergamini","year":"2017","unstructured":"Bergamini\u00a0A, Pisano\u00a0C, Di Napoli\u00a0M, et\u00a0al. Cisplatin can be safely administered to ovarian cancer patients with hypersensitivity to carboplatin. Gynecol Oncol. 2017;144(1):72\u20136.","journal-title":"Gynecol Oncol"},{"issue":"6","key":"938_CR11","doi-asserted-by":"publisher","first-page":"1894","DOI":"10.1016\/j.jaip.2019.01.057","volume":"7","author":"J Pasteur","year":"2019","unstructured":"Pasteur\u00a0J, Favier\u00a0L, Pernot\u00a0C, et al. Low cross-reactivity between cisplatin and other platinum salts. J\u00a0Allergy Clin Immunol Pract. 2019;7(6):1894\u2013900.","journal-title":"J Allergy Clin Immunol Pract"}],"container-title":["Wiener Medizinische Wochenschrift"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10354-022-00938-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10354-022-00938-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10354-022-00938-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T09:27:07Z","timestamp":1693819627000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10354-022-00938-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,20]]},"references-count":11,"journal-issue":{"issue":"11-12","published-print":{"date-parts":[[2023,9]]}},"alternative-id":["938"],"URL":"https:\/\/doi.org\/10.1007\/s10354-022-00938-x","relation":{},"ISSN":["0043-5341","1563-258X"],"issn-type":[{"type":"print","value":"0043-5341"},{"type":"electronic","value":"1563-258X"}],"subject":[],"published":{"date-parts":[[2022,5,20]]},"assertion":[{"value":"27 December 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 April 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 May 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"E.\u00a0Marquart, A.\u00a0Jalili, N.\u00a0Mothes-Luksch, S.N.\u00a0Wagner, and T.\u00a0Kinaciyan declare that they have no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"For this case report no studies with human subjects or animals were performed. All investigations performed were in accordance with the ethical standards. As no images or other information within the manuscript identifies the patient, consent was not deemed necessary.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical standards"}}]}}