{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:15:52Z","timestamp":1792782952826,"version":"4.5.0"},"reference-count":12,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T00:00:00Z","timestamp":1781222400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T00:00:00Z","timestamp":1781222400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100005688","name":"Gottfried und Julia Bangerter-Rhyner-Stiftung","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005688","id-type":"DOI","asserted-by":"publisher"}]},{"name":"University of Bern","id":[{"id":"https:\/\/ror.org\/02k7v4d05","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Wien Med Wochenschr"],"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Scedosporium apiospermum<\/jats:italic>\n                    is a\u00a0ubiquitous species of ascomycete fungi. Human infections occur mostly as opportunistic infections in immunocompromised patients. Risk factors for immunocompetent patients are penetrating trauma, surgery, and near-drowning accidents. We report a\u00a0complicated postsurgical infection with\n                    <jats:italic>S.\u00a0apiospermum<\/jats:italic>\n                    in a\u00a066-year-old immunocompetent adult. After microsurgical lumbar decompression, the patient developed an extensive infection in the area of the operation with sub- and epidural abscess collection, spondylodiscitis, polyradiculitis, and arachnoiditis.\n                    <jats:italic>S.\u00a0apiospermum<\/jats:italic>\n                    was recovered from multiple cultures of tissue samples as well as from implant material. Despite early initiation of voriconazole therapy and surgical intervention, the progressive infection of multiple lumbar nerve roots could not be prevented and the patient developed distal sensorimotor paraparesis. Only after 10\u00a0months of continuous oral voriconazole therapy and repeated surgical procedures to replace all implant material did stabilization and clinical improvement occur. Finally, fungus was no longer detected and the patient slowly but steadily regained walking ability.\n                  <\/jats:p>","DOI":"10.1007\/s10354-026-01164-5","type":"journal-article","created":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T07:16:54Z","timestamp":1781248614000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A\u00a0complicated case of a\u00a0spinal Scedosporium apiospermum infection with a\u00a0favorable outcome\u2014case report","Ein komplizierter Fall einer spinalen Scedosporium apiospermum Infektion mit gutem Outcome \u2013 Kasuistik"],"prefix":"10.1007","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8949-0645","authenticated-orcid":false,"given":"Anelia","family":"Dietmann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arsany","family":"Hakim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hana","family":"You","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Bigdon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus","family":"Hanke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Scheidegger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Zimmerli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,6,12]]},"reference":[{"key":"1164_CR1","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1128\/CMR.00039-07","volume":"21","author":"KJ Cortez","year":"2008","unstructured":"Cortez\u00a0KJ, Roilides\u00a0E, Quiroz-Telles\u00a0F, Meletiadis\u00a0J, Antachopoulos\u00a0C, Knudsen\u00a0T, et\u00a0al. Infections Caused by Scedosporium spp. Clinical Microbiology Reviews. 2008;21:157\u201397. https:\/\/doi.org\/10.1128\/CMR.00039-07.","journal-title":"Clinical Microbiology Reviews"},{"key":"1164_CR2","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1056\/NEJMra1216008","volume":"371","author":"M McCarthy","year":"2014","unstructured":"McCarthy\u00a0M, Rosengart\u00a0A, Schuetz\u00a0AN, Kontoyiannis\u00a0DP, Walsh\u00a0TJ. Mold Infections of the Central Nervous System. New England Journal of Medicine. 2014;371:150\u201360. https:\/\/doi.org\/10.1056\/NEJMra1216008.","journal-title":"New England Journal of Medicine"},{"key":"1164_CR3","doi-asserted-by":"publisher","first-page":"1743","DOI":"10.1128\/AAC.01388-07","volume":"52","author":"P Troke","year":"2008","unstructured":"Troke\u00a0P, Aguirrebengoa\u00a0K, Arteaga\u00a0C, Ellis\u00a0D, Heath\u00a0CH, Lutsar\u00a0I, et\u00a0al. Treatment of Scedosporiosis with Voriconazole: Clinical Experience with 107 Patients. Antimicrobial Agents and Chemotherapy. 2008;52:1743\u201350. https:\/\/doi.org\/10.1128\/AAC.01388-07.","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"1164_CR4","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1111\/1469-0691.12465","volume":"20","author":"AM Tortorano","year":"2014","unstructured":"Tortorano\u00a0AM, Richardson\u00a0M, Roilides\u00a0E, van Diepeningen\u00a0A, Caira\u00a0M, Munoz\u00a0P, et\u00a0al. ESCMID and ECMM joint guidelines on diagnosis and management of hyalohyphomycosis: Fusarium spp., Scedosporium spp. and others. Clinical Microbiology and Infection. 2014;20:27\u201346. https:\/\/doi.org\/10.1111\/1469-0691.12465.","journal-title":"Clinical Microbiology and Infection"},{"key":"1164_CR5","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1111\/j.1439-0507.2007.01388.x","volume":"50","author":"A Katragkou","year":"2007","unstructured":"Katragkou\u00a0A, Dotis\u00a0J, Kotsiou\u00a0M, Tamiolaki\u00a0M, Roilides\u00a0E. Scedosporium apiospermum infection after near-drowning. Mycoses. 2007;50:412\u201321. https:\/\/doi.org\/10.1111\/j.1439-0507.2007.01388.x.","journal-title":"Mycoses"},{"key":"1164_CR6","doi-asserted-by":"publisher","first-page":"550","DOI":"10.4103\/IJPM.IJPM_742_16","volume":"60","author":"D Rynga","year":"2017","unstructured":"Rynga\u00a0D, Capoor\u00a0M, Varshney\u00a0S, Naik\u00a0M, Gupta\u00a0V. Scedosporium apiospermum, an emerging pathogen in India: Case series and review of literature. Indian Journal of Pathology and Microbiology. 2017;60:550. https:\/\/doi.org\/10.4103\/IJPM.IJPM_742_16.","journal-title":"Indian Journal of Pathology and Microbiology"},{"key":"1164_CR7","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1016\/j.amjoto.2006.08.017","volume":"28","author":"BJ Baumgartner","year":"2007","unstructured":"Baumgartner\u00a0BJ, Rakita\u00a0RM, Backous\u00a0DD. Scedosporium apiospermum otomycosis. Am J Otolaryngol. 2007;28:254\u20136. https:\/\/doi.org\/10.1016\/j.amjoto.2006.08.017.","journal-title":"American Journal of Otolaryngology"},{"key":"1164_CR8","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2011\/460313","volume":"2011","author":"B Luijk","year":"2011","unstructured":"Luijk\u00a0B, Ekkelenkamp\u00a0MB, De Jong\u00a0PA, Kwakkel-van Erp\u00a0JM, Grutters\u00a0JC, van Kessel\u00a0DA, et\u00a0al. Effective Prolonged Therapy with Voriconazole in a Lung Transplant Recipient with Spondylodiscitis Induced by Scedosporium apiospermum. Case Reports in Infectious Diseases. 2011;2011:1\u20134. https:\/\/doi.org\/10.1155\/2011\/460313.","journal-title":"Case Reports in Infectious Diseases"},{"key":"1164_CR9","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1097\/00024720-200210000-00014","volume":"15","author":"NB Levine","year":"2002","unstructured":"Levine\u00a0NB, Kurokawa\u00a0R, Fichtenbaum\u00a0CJ, Howington\u00a0JA, Kuntz\u00a0C. 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Ther Adv Infect Dis. 2024; https:\/\/doi.org\/10.1177\/20499361231224980.","journal-title":"Ther Adv Infect Dis"}],"container-title":["Wiener Medizinische Wochenschrift"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10354-026-01164-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10354-026-01164-5","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10354-026-01164-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T12:43:07Z","timestamp":1792672987000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10354-026-01164-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,12]]},"references-count":12,"alternative-id":["1164"],"URL":"https:\/\/doi.org\/10.1007\/s10354-026-01164-5","relation":{},"ISSN":["0043-5341","1563-258X"],"issn-type":[{"value":"0043-5341","type":"print"},{"value":"1563-258X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,12]]},"assertion":[{"value":"27 February 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 May 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 June 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"A.\u00a0Dietmann, A.\u00a0Hakim, H.\u00a0You, S.\u00a0Bigdon, M.\u00a0Hanke, O.\u00a0Scheidegger and S.\u00a0Zimmerli declare that they have no competing interests.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Written informed consent was obtained from the patient for the publication of this case report.","order":2,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":3,"name":"Ethics","label":"Ethics approval and consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}}]}}