{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T06:14:32Z","timestamp":1792649672408,"version":"4.5.0"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2012,6,5]],"date-time":"2012-06-05T00:00:00Z","timestamp":1338854400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Jpn J Ophthalmol"],"published-print":{"date-parts":[[2012,7]]},"DOI":"10.1007\/s10384-012-0150-7","type":"journal-article","created":{"date-parts":[[2012,6,4]],"date-time":"2012-06-04T11:48:38Z","timestamp":1338810518000},"page":"383-389","source":"Crossref","is-referenced-by-count":202,"title":["Clinical features and diagnostic significance of the intraocular fluid of 217 patients with intraocular lymphoma"],"prefix":"10.1007","volume":"56","author":[{"name":"The Japanese Intraocular Lymphoma Study Group","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keisuke","family":"Kimura","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihiko","family":"Usui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Goto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2012,6,5]]},"reference":[{"key":"150_CR1","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1177\/107327489800500403","volume":"5","author":"DS Bardenstein","year":"1998","unstructured":"Bardenstein DS. Intraocular Lymphoma. Cancer Control. 1998;5:317\u201325.","journal-title":"Cancer Control"},{"key":"150_CR2","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/s10384-006-0383-4","volume":"51","author":"H Goto","year":"2007","unstructured":"Goto H, Mochizuki M, Yamaki K, Kotake S, Usui M, Ohno S. Epidemiological survey of intraocular inflammation in Japan. Jpn J Ophthalmol. 2007;51:41\u20134.","journal-title":"Jpn J Ophthalmol"},{"key":"150_CR3","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1016\/S0161-6420(93)31469-7","volume":"100","author":"SM Whitcup","year":"1993","unstructured":"Whitcup SM, de Smet MD, Rubin BI, Palestine AG, Martin DF, Burnier M Jr, et al. Intraocular lymphoma. Clinical and histopathologic diagnosis. Ophthalmology. 1993;100:1399\u2013406.","journal-title":"Ophthalmology"},{"key":"150_CR4","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1080\/09273940902834413","volume":"17","author":"D Wakefield","year":"2009","unstructured":"Wakefield D, Zierhut M. Intraocular lymphoma: more questions than answers. Ocul Immunol Inflamm. 2009;17:6\u201310.","journal-title":"Ocul Immunol Inflamm"},{"key":"150_CR5","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1016\/S0161-6420(88)33145-3","volume":"95","author":"DH Char","year":"1988","unstructured":"Char DH, Ljung BM, Miller T, Phillips T. Primary intraocular lymphoma (ocular reticulum cell sarcoma) diagnosis and management. Ophthalmology. 1988;95:625\u201330.","journal-title":"Ophthalmology"},{"key":"150_CR6","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1001\/archopht.1997.01100160327010","volume":"115","author":"SM Whitcup","year":"1997","unstructured":"Whitcup SM, Stark-Vancs V, Wittes RE, Solomon D, Podgor MJ, Nussenblatt RB, et al. Association of interleukin 10 in the vitreous and cerebrospinal fluid and primary central nervous system lymphoma. Arch Ophthalmol. 1997;115:1157\u201360.","journal-title":"Arch Ophthalmol"},{"key":"150_CR7","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1002\/cncr.21191","volume":"104","author":"JM Baehring","year":"2005","unstructured":"Baehring JM, Androudi S, Longtine JJ, Betensky RA, Sklar J, Foster CS, et al. Analysis of clonal immunoglobulin heavy chain rearrangements in ocular lymphoma. Cancer. 2005;104:591\u20137.","journal-title":"Cancer"},{"key":"150_CR8","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1007\/s10384-009-0662-y","volume":"53","author":"S Sugita","year":"2009","unstructured":"Sugita S, Takase H, Sugamoto Y, Arai A, Miura O, Mochizuki M. Diagnosis of intraocular lymphoma by polymerase chain reaction analysis and cytokine profiling of the vitreous fluid. Jpn J Ophthalmol. 2009;53:209\u201314.","journal-title":"Jpn J Ophthalmol"},{"key":"150_CR9","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1007\/s10384-006-0406-1","volume":"51","author":"K Ohta","year":"2007","unstructured":"Ohta K, Sano K, Suzuki T, Hidaka E, Yoshida A, Kikuchi T. B cell clonality of primary central nervous system and primary intraocular lymphomas. Jpn J Ophthalmol. 2007;51:147\u20139.","journal-title":"Jpn J Ophthalmol"},{"key":"150_CR10","doi-asserted-by":"crossref","first-page":"1664","DOI":"10.1016\/S0161-6420(98)99036-4","volume":"105","author":"DF Shen","year":"1998","unstructured":"Shen DF, Zhuang Z, LeHoang P, Boni R, Zheng S, Nussenblatt RB, et al. Utility of microdissection and polymerase chain reaction for the detection of immunoglobulin gene rearrangement and translocation in primary intraocular lymphoma. Ophthalmology. 1998;105:1664\u20139.","journal-title":"Ophthalmology"},{"key":"150_CR11","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.5858\/133.8.1233","volume":"133","author":"K Raparia","year":"2009","unstructured":"Raparia K, Chang CC, Chevez-Barrios P. Intraocular lymphoma: diagnostic approach and immunophenotypic findings in vitrectomy specimens. Arch Pathol Lab Med. 2009;133:1233\u20137.","journal-title":"Arch Pathol Lab Med"},{"key":"150_CR12","doi-asserted-by":"crossref","unstructured":"Chan CC, Gonzales JA. Primary intraocular lymphoma. Singapore: World Scientific; 2007. p. 19\u201342.","DOI":"10.1142\/9789812771049_0004"},{"key":"150_CR13","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1016\/S0161-6420(87)33256-7","volume":"94","author":"LN Freeman","year":"1987","unstructured":"Freeman LN, Schachat AP, Knox DL, Michels RG, Green WR. Clinical features, laboratory investigations, and survival in ocular reticulum cell sarcoma. Ophthalmology. 1987;94:1631\u20139.","journal-title":"Ophthalmology"},{"key":"150_CR14","doi-asserted-by":"crossref","first-page":"1851","DOI":"10.1093\/annonc\/mdm340","volume":"18","author":"SA Grimm","year":"2007","unstructured":"Grimm SA, Pulido JS, Jahnke K, Schiff D, Hall AJ, Shenkier TN, et al. Primary intraocular lymphoma: an International Primary Central Nervous System Lymphoma Collaborative Group Report. Ann Oncol. 2007;18:1851\u20135.","journal-title":"Ann Oncol"},{"key":"150_CR15","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1007\/s00417-005-0138-9","volume":"244","author":"K Jahnke","year":"2006","unstructured":"Jahnke K, Korfel A, Komm J, Bechrakis NE, Stein H, Thiel E, et al. Intraocular lymphoma 2000\u20132005: results of a retrospective multicentre trial. Graefes Arch Clin Exp Ophthalmol. 2006;244:663\u20139.","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"150_CR16","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1038\/sj.eye.6700378","volume":"17","author":"PM Hoffman","year":"2003","unstructured":"Hoffman PM, McKelvie P, Hall AJ, Stawell RJ, Santamaria JD. Intraocular lymphoma: a series of 14 patients with clinicopathological features and treatment outcomes. Eye (Lond). 2003;17:513\u201321.","journal-title":"Eye (Lond)"},{"key":"150_CR17","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1016\/0002-9394(51)90691-5","volume":"34","author":"EL Cooper","year":"1951","unstructured":"Cooper EL, Riker JL. Malignant lymphoma of the uveal tract. Am J Ophthalmol. 1951;34:1153\u20138.","journal-title":"Am J Ophthalmol"},{"key":"150_CR18","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1023\/A:1006290032052","volume":"43","author":"M Schabet","year":"1999","unstructured":"Schabet M. Epidemiology of primary CNS lymphoma. J Neurooncol. 1999;43:199\u2013201.","journal-title":"J Neurooncol"},{"key":"150_CR19","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1007\/s11912-005-0029-6","volume":"7","author":"SK Kim","year":"2005","unstructured":"Kim SK, Chan CC, Wallace DJ. Management of primary intraocular lymphoma. Curr Oncol Rep. 2005;7:74\u20139.","journal-title":"Curr Oncol Rep"},{"key":"150_CR20","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1007\/s00417-004-0973-0","volume":"242","author":"SE Coupland","year":"2004","unstructured":"Coupland SE, Heimann H, Bechrakis NE. Primary intraocular lymphoma: a review of the clinical histopathological and molecular biological features. Graefes Arch Clin Exp Ophthalmol. 2004;242:901\u201313.","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"150_CR21","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1212\/01.wnl.0000327672.04729.8c","volume":"71","author":"SA Grimm","year":"2008","unstructured":"Grimm SA, McCannel CA, Omuro AM, Ferreri AJ, Blay JY, Neuwelt EA, et al. Primary CNS lymphoma with intraocular involvement: International PCNSL Collaborative Group Report. Neurology. 2008;71:1355\u201360.","journal-title":"Neurology"},{"key":"150_CR22","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/0002-9394(75)90453-5","volume":"79","author":"TG Klingele","year":"1975","unstructured":"Klingele TG, Hogan MJ. Ocular reticulum cell sarcoma. Am J Ophthalmol. 1975;79:39\u201347.","journal-title":"Am J Ophthalmol"},{"key":"150_CR23","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1001\/archopht.1975.01010020961005","volume":"93","author":"RG Michels","year":"1975","unstructured":"Michels RG, Knox DL, Erozan YS, Green WR. Intraocular reticulum cell sarcoma. Diagnosis by pars plana vitrectomy. Arch Ophthalmol. 1975;93:1331\u20135.","journal-title":"Arch Ophthalmol"},{"key":"150_CR24","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1046\/j.1365-2141.2003.04800.x","volume":"124","author":"H Merle-Beral","year":"2004","unstructured":"Merle-Beral H, Davi F, Cassoux N, Baudet S, Colin C, Gourdet T, et al. Biological diagnosis of primary intraocular lymphoma. Br J Haematol. 2004;124:469\u201373.","journal-title":"Br J Haematol"},{"key":"150_CR25","doi-asserted-by":"crossref","first-page":"1671","DOI":"10.1016\/S0161-6420(03)00811-X","volume":"110","author":"LA Wolf","year":"2003","unstructured":"Wolf LA, Reed GF, Buggage RR, Nussenblatt RB, Chan CC. Vitreous cytokine levels. Ophthalmology. 2003;110:1671\u20132.","journal-title":"Ophthalmology"},{"key":"150_CR26","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1097\/00006982-200106000-00023","volume":"21","author":"GA Levy-Clarke","year":"2001","unstructured":"Levy-Clarke GA, Byrnes GA, Buggage RR, Shen DF, Filie AC, Caruso RC, et al. Primary intraocular lymphoma diagnosed by fine needle aspiration biopsy of a subretinal lesion. Retina. 2001;21:281\u20134.","journal-title":"Retina"},{"key":"150_CR27","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1080\/09273940903108544","volume":"17","author":"HN Sen","year":"2009","unstructured":"Sen HN, Bodaghi B, Hoang PL, Nussenblatt R. Primary intraocular lymphoma: diagnosis and differential diagnosis. Ocul Immunol Inflamm. 2009;17:133\u201341.","journal-title":"Ocul Immunol Inflamm"},{"key":"150_CR28","doi-asserted-by":"crossref","first-page":"1800","DOI":"10.1080\/10428190600632881","volume":"47","author":"K Isobe","year":"2006","unstructured":"Isobe K, Ejima Y, Tokumaru S, Shikama N, Suzuki G, Takemoto M, et al. Treatment of primary intraocular lymphoma with radiation therapy: a multi-institutional survey in Japan. Leuk Lymphoma. 2006;47:1800\u20135.","journal-title":"Leuk Lymphoma"},{"key":"150_CR29","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1001\/archopht.1997.01100160322009","volume":"115","author":"BC Fishburne","year":"1997","unstructured":"Fishburne BC, Wilson DJ, Rosenbaum JT, Neuwelt EA. Intravitreal methotrexate as an adjunctive treatment of intraocular lymphoma. Arch Ophthalmol. 1997;115:1152\u20136.","journal-title":"Arch Ophthalmol"},{"key":"150_CR30","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1007\/s10384-005-0327-4","volume":"50","author":"JK Wang","year":"2006","unstructured":"Wang JK, Yang CM, Lin CP, Shan YD, Lo AY, Tien HF. An Asian patient with intraocular lymphoma treated by intravitreal methotrexate. Jpn J Ophthalmol. 2006;50:474\u20138.","journal-title":"Jpn J Ophthalmol"},{"key":"150_CR31","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1007\/s10384-008-0519-9","volume":"52","author":"R Sou","year":"2008","unstructured":"Sou R, Ohguro N, Maeda T, Saishin Y, Tano Y. Treatment of primary intraocular lymphoma with intravitreal methotrexate. Jpn J Ophthalmol. 2008;52:167\u201374.","journal-title":"Jpn J Ophthalmol"},{"key":"150_CR32","first-page":"711","volume":"9","author":"TT Batchelor","year":"2003","unstructured":"Batchelor TT, Kolak G, Ciordia R, Foster CS, Henson JW. High-dose methotrexate for intraocular lymphoma. Clin Cancer Res. 2003;9:711\u20135.","journal-title":"Clin Cancer Res"}],"container-title":["Japanese Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10384-012-0150-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10384-012-0150-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10384-012-0150-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,16]],"date-time":"2022-01-16T12:00:36Z","timestamp":1642334436000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10384-012-0150-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,6,5]]},"references-count":32,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012,7]]}},"alternative-id":["150"],"URL":"https:\/\/doi.org\/10.1007\/s10384-012-0150-7","relation":{},"ISSN":["0021-5155","1613-2246"],"issn-type":[{"value":"0021-5155","type":"print"},{"value":"1613-2246","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,6,5]]}}}